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List of works by Eitan Amir

25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1

scientific article

A Matched Cohort Study of Patients With End-Stage Heart Failure from Anthracycline-Induced Cardiomyopathy Requiring Advanced Cardiac Support

scientific article published on 23 August 2016

A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229)

scientific article published on 16 August 2019

A Population-Based Study of Cardiovascular Mortality Following Early-Stage Breast Cancer

scientific article

A Risk-benefit Analysis of Prophylactic Anticoagulation for Patients with Metastatic Germ Cell Tumours Undergoing First-line Chemotherapy

scientific article published on 05 October 2020

A case-control study analyzing mannitol dosing for prevention of cisplatin-induced acute nephrotoxicity

scientific article published on 03 May 2018

A critique of the fragility index

A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO

scientific article

A phase 2 trial exploring the effects of high-dose (10,000 IU/day) vitamin D(3) in breast cancer patients with bone metastases

scientific article published in January 2010

A phase II, multicentre trial evaluating the efficacy of de-escalated bisphosphonate therapy in metastatic breast cancer patients at low-risk of skeletal-related events.

scientific article published on 18 March 2014

A prospective intervention to improve happiness and reduce burnout in oncologists

scientific article published on 30 November 2018

A randomized phase II trial of geriatric assessment and management for older cancer patients.

scientific article published on 25 July 2017

A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer

scientific article published in January 2010

A randomized, phase III trial exploring the effects of neoadjuvant sequential treatment with steroidal (exemestane) and nonsteroidal (anastrozole) aromatase inhibitors on biomarkers in postmenopausal women with hormone receptor-positive locally adva

ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone.

scientific article

Absolute benefit from adjuvant chemotherapy in contemporary clinical trials: A systemic review and meta-analysis

article

Absolute benefits of aromatase inhibitors in adjuvant treatment of breast cancer: should we know more?

scientific article published on 10 May 2010

Acquisition of metastatic tissue from patients with bone metastases from breast cancer.

scientific article published on 27 November 2010

Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

scientific article

Acute Kidney Injury in Patients Receiving Systemic Treatment for Cancer: A Population-Based Cohort Study

scientific article published on 13 November 2018

Acute kidney injury associated with immune checkpoint inhibitor therapy: incidence, risk factors and outcomes

scientific article published on 01 June 2020

Addition of bevacizumab to chemotherapy for treatment of solid tumors: similar results but different conclusions

scientific article published on 13 December 2010

Addition of pathology and biomarker information significantly improves the performance of the Manchester scoring system for BRCA1 and BRCA2 testing

article

Adjuvant Radiation Therapy After Radical Nephrectomy in Patients with Localized Renal Cell Carcinoma: A Systematic Review and Meta-analysis

scientific article published on 05 November 2018

Adjuvant bisphosphonate therapy for breast cancer patients: Standard of care or future direction?

scientific article published on 23 March 2009

Adjuvant chemotherapy and outcomes in patients with nodal and resection margin-negative pancreatic ductal adenocarcinoma: A systematic review and meta-analysis

scientific article published on 05 March 2019

Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis.

scientific article

Advances in cancer therapeutics and patient access to new drugs.

scientific article published on March 2011

Altered calcium metabolism in patients on long-term bisphosphonate therapy for metastatic breast cancer.

scientific article published in July 2009

Amenorrhoea, menopause, and endocrine therapy for breast cancer

scientific article published on 3 December 2009

An economic analysis of the INTEREST trial, a randomized trial of docetaxel versus gefitinib as second-/third-line therapy in advanced non-small-cell lung cancer

scientific article published on 27 January 2011

Androgen receptor expression and outcomes in early breast cancer: a systematic review and meta-analysis

scientific article

Anticancer drugs approved by the Food and Drug Administration for gastrointestinal malignancies: Clinical benefit and price considerations

scientific article published on 07 March 2019

Antivascular agents for non-small-cell lung cancer: current status and future directions.

scientific article

Are adjuvant bisphosphonates now standard of care of women with early stage breast cancer? A debate from the Canadian Bone and the Oncologist New Updates meeting

scientific article

Aromatase inhibitors for prevention of breast cancer in postmenopausal women: a narrative review

scientific article

Assessing women at high risk of breast cancer: a review of risk assessment models

scientific article published on 28 April 2010

Assessment of Frequency and Reporting of Changes in Cancer Trial Design After Initiation of Patient Accrual

scientific article published on 01 January 2019

Assessment of frequency and reporting of design changes among clinical drug trials published in influential medical journals

scientific article published on 19 August 2019

Assisting with Decision-Making: How Standardized Information Impacts Breast Cancer Patient Decisions Regarding Fertility Trade-Offs and Chemotherapy

scientific article published on 26 June 2019

Association Between Data Sources and US Food and Drug Administration Drug Safety Communications

scientific article published on 03 September 2019

Association between BMI, vitamin D, and estrogen levels in postmenopausal women using adjuvant letrozole: a prospective study

scientific article published on 12 June 2020

Association between androgen receptor expression, Ki-67 and the 21-gene recurrence score in non-metastatic, lymph node-negative, estrogen receptor-positive and HER2-negative breast cancer

scientific article published on 15 June 2015

Association of Early-Stage Breast Cancer and Subsequent Chemotherapy With Risk of Atrial Fibrillation

scientific article published on 04 September 2019

Association of Metabolic, Inflammatory, and Tumor Markers With Circulating Tumor Cells in Metastatic Breast Cancer

scientific article published on 01 April 2018

Association of aromatase inhibitors with coronary heart disease in women with early breast cancer

scientific article published on 18 February 2014

Association of the Timing of Pregnancy With Survival in Women With Breast Cancer

scientific article published on 9 March 2017

Associations between safety, tolerability, and toxicity and the reporting of health-related quality of life in phase III randomized trials in common solid tumors

scientific article published on 04 September 2020

Author financial conflicts of interest, industry funding, and clinical practice guidelines for anticancer drugs

scientific article

Benefit and harms of new anti-cancer drugs

scientific article published on June 2013

Benefits and harms of detecting clinically occult breast cancer

scientific article

Bias in reporting of end points of efficacy and toxicity in randomized, clinical trials for women with breast cancer

scientific article published on 9 January 2013

Bias in reporting of randomised clinical trials in oncology

scientific article

Biological insights into effective and antagonistic combinations of targeted agents with chemotherapy in solid tumors

scientific article published on March 2014

Biopsy confirmation of metastatic breast cancer: interim results of a prospective biopsy study

Biosimilars of biological drug therapies: regulatory, clinical and commercial considerations.

scientific article

Bone Modifier Use as Adjuvant Therapy for Early Breast Cancer

scientific article published on March 2017

Bone-targeted therapy for metastatic breast cancer-Where do we go from here? A commentary from the BONUS 8 meeting.

scientific article

Breast Cancer Chemoprevention Gets Personal ⬇️

scientific article published on 02 May 2011

Breast Cancer Therapy-Related Cardiac Dysfunction in Adult Women Treated in Routine Clinical Practice: A Population-Based Cohort Study

scientific article

CCN3 impairs osteoblast and stimulates osteoclast differentiation to favor breast cancer metastasis to bone

scientific article

CMR and Tissue Characterization: Don't Forget the Strain!

scientific article published on 01 July 2019

Can Quantitative CMR Tissue Characterization Adequately Identify Cardiotoxicity During Chemotherapy?: Impact of Temporal and Observer Variability

scientific article published on 18 December 2019

Capecitabine in early breast cancer: A meta-analysis of randomised controlled trials

scientific article published on 26 March 2017

Cardiac Outcomes in Pregnant Women With Treated Cancer

scientific article published on 01 October 2018

Cardiac Outcomes in Survivors of Pediatric and Adult Cancers

scientific article published on 2 March 2016

Cardioprotective Effect of Statins in Patients With HER2-Positive Breast Cancer Receiving Trastuzumab Therapy

scientific article published on 04 December 2018

Cardiovascular toxicity of angiogenesis inhibitors in treatment of malignancy: A systematic review and meta-analysis.

scientific article published on 30 December 2016

Cardiovascular toxicity of multi-tyrosine kinase inhibitors in advanced solid tumors: a population-based observational study

scientific article

Change in Neutrophil-to-lymphocyte Ratio in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma as a Prognosticator and Biomarker of Efficacy.

scientific article

Characteristics of Immune Checkpoint Inhibitors Trials Associated With Inclusion of Patients With HIV: A Systematic Review and Meta-analysis

scientific article published on 01 November 2019

Chemotherapy treatment decision-making experiences of older adults with cancer, their family members, oncologists and family physicians: a mixed methods study

scientific article published on 9 November 2016

Chemotherapy: dose-dense treatment for triple-negative breast cancer

scientific article published on 01 February 2010

Circulating DNA and Survival in Solid Tumors

scientific article

Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes

scientific article

Clinical and Cost-effectiveness of a Comprehensive geriatric assessment and management for Canadian elders with Cancer-the 5C study: a study protocol for a randomised controlled phase III trial

scientific article published on 10 May 2019

Clinical benefit and cost of breakthrough cancer drugs approved by the US Food and Drug Administration

scientific article published on 22 July 2020

Clinical predictors of benefit from fulvestrant in advanced breast cancer: A Meta-analysis of randomized controlled trials

scientific article published on 22 February 2016

Clinical research: show us the data

scientific article

Clinical trial design in biosimilar drug development.

scientific article

Comparison of absolute benefits of anticancer therapies determined by snapshot and area methods

scientific article published on 24 June 2012

Comparison of treatment-related adverse events of different Cyclin-dependent kinase 4/6 inhibitors in metastatic breast cancer: A network meta-analysis

scientific article published on 17 August 2020

Competing risks of extended adjuvant aromatase inhibitors

scientific article published on 30 November 2018

Cost effectiveness of outpatient treatment for febrile neutropaenia in adult cancer patients.

scientific article

Cost-effectiveness analysis of extended adjuvant endocrine therapy in the treatment of post-menopausal women with hormone receptor positive breast cancer.

scientific article published on 26 April 2014

Cost-effectiveness of outpatient management for febrile neutropenia in children with cancer

scientific article published on 10 January 2011

Cytochrome P450 2D6 and outcomes of adjuvant tamoxifen therapy: results of a meta-analysis

scientific article published on 8 May 2010

Deescalating Adjuvant Trastuzumab in HER2-Positive Early-Stage Breast Cancer: A Systemic Review and Meta-Analysis

scientific article published on 11 May 2019

Defining ovarian failure in amenorrheic young breast cancer patients.

scientific article published on 07 July 2010

Delivering affordable cancer care in high-income countries

article

Demystifying the role of tumor HPV status in recurrent and/or metastatic squamous cell carcinoma of the head and neck.

scientific article published on 25 February 2014

Determinants of the recommended phase 2 dose of molecular targeted agents

scientific article published on 9 February 2017

Developing a prediction model for benefit from fulvestrant in heavily pretreated metastatic breast cancer patients.

scientific article published on 23 June 2009

Development and validation of a multivariable prediction model for major adverse cardiovascular events after early stage breast cancer: a population-based cohort study

scientific article published on 18 July 2019

Discordance between receptor status in primary and metastatic breast cancer: an exploratory study of bone and bone marrow biopsies

scientific article published on 27 September 2008

Do we have to change the way targeted drugs are developed?

scientific article published on 21 June 2010

Does a dedicated program for young breast cancer patients affect the likelihood of fertility preservation discussion and referral?

scientific article published on 21 March 2016

Does estrogen play a role in response to adjuvant bone-targeted therapies?

scientific article

Dual blockade of HER2 - twice as good or twice as toxic?

scientific article published on 28 June 2012

Dual targeting of HER2-positive breast cancer with trastuzumab emtansine and pertuzumab: understanding clinical trial results

scientific article published on 07 August 2018

EQUATOR-Oncology: reducing the latitude of cancer trial design and reporting

scientific article published on 22 February 2018

Economic evaluation of hormonal therapies for postmenopausal women with estrogen receptor-positive early breast cancer in Canada

scientific article

Effect of multifocality and multicentricity on outcome in early stage breast cancer: a systematic review and meta-analysis

scientific article

Effects of de-escalated bisphosphonate therapy on bone turnover biomarkers in breast cancer patients with bone metastases

scientific article

Effects of de-escalated bisphosphonate therapy on the Functional Assessment of Cancer Therapy-Bone Pain, Brief Pain Inventory and bone biomarkers

scientific article

Efficacy of extended adjuvant therapy with aromatase inhibitors in early breast cancer among common clinicopathologically-defined subgroups: A systematic review and meta-analysis

scientific article published on 24 August 2017

Efficacy, safety, tolerability and price of newly approved drugs in solid tumors.

scientific article

Efficacy-effectiveness gap as an obstacle to translating clinical trials to clinical practice

scientific article published on 6 April 2015

Endpoint selection in HER2-positive early breast cancer

scientific article published on 29 January 2019

Epidermal growth factor receptor overexpression and outcomes in early breast cancer: A systematic review and a meta-analysis

scientific article published on 31 October 2017

Epigenetic modulation of FOXM1-gene interacting network by BET inhibitors in breast cancer

scientific article published on 11 September 2018

Erratum to: 25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1.

scientific article published on 5 August 2012

Evaluation of breast cancer risk assessment packages in the family history evaluation and screening programme

scientific article

Evaluation of circulating tumor cells and serological cell death biomarkers in small cell lung cancer patients undergoing chemotherapy

scientific article published on 23 July 2009

Evolution in sites of recurrence over time in breast cancer patients treated with adjuvant endocrine therapy

scientific article published on 24 August 2018

Evolution in the eligibility criteria of randomized controlled trials for systemic cancer therapies

scientific article published on 31 December 2015

Evolution in the risk of adverse events of adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer

scientific article published on 01 June 2020

Evolution of Randomized Trials in Advanced/Metastatic Soft Tissue Sarcoma: End Point Selection, Surrogacy, and Quality of Reporting

scientific article published on 7 March 2016

Evolution of clinical trial design in early drug development: systematic review of expansion cohort use in single-agent phase I cancer trials

scientific article published on 14 October 2013

Evolution of sites of recurrence after early breast cancer over the last 20 years: implications for patient care and future research

scientific article published on 17 May 2013

Examination of the mechanisms of osteolysis in patients with metastatic breast cancer.

scientific article published on May 2009

Expedited approval of cancer drugs without randomized controlled trials: Too good to be true?

scientific article published on 24 July 2018

Expression of MHC class I, HLA-A and HLA-B identifies immune-activated breast tumors with favorable outcome

scientific article published on 03 July 2019

Extended adjuvant tamoxifen for early breast cancer: a meta-analysis.

scientific article

Failures in Phase III: Causes and Consequences

scientific article published on 01 October 2015

Feasibility randomised controlled trial of remote symptom chemotherapy toxicity monitoring using the Canadian adapted Advanced Symptom Management System (ASyMS-Can): a study protocol

scientific article published on 17 June 2020

Fertility preservation in post-pubescent female cancer patients: A practical guideline for clinicians

scientific article published on 3 November 2017

Filling in the gaps: reporting of concurrent supportive care therapies in breast cancer chemotherapy trials.

scientific article

Fulvestrant for advanced breast cancer: a meta-analysis

scientific article published on 10 June 2013

Functional transcriptomic annotation and protein-protein interaction analysis identify EZH2 and UBE2C as key upregulated proteins in ovarian cancer.

scientific article published on 25 March 2018

Future directions for bone metastasis research - highlights from the 2015 bone and the Oncologist new updates conference (BONUS)

scientific article

General Overview and Treatment Recommendations for Young Women with Breast Cancer.

scientific article published on March 2017

Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors

article

Genetic polymorphisms as predictive and prognostic biomarkers in gynecological cancers: a systematic review

scientific article

HER2 heterogeneity and resistance to anti-HER2 antibody-drug conjugates

scientific article published on 31 January 2020

HER3 overexpression and survival in solid tumors: a meta-analysis

scientific article published on 8 December 2012

HYPE or HOPE: the prognostic value of infiltrating immune cells in cancer

scientific article published on 13 July 2017

HYPE or HOPE: the prognostic value of infiltrating immune cells in cancer

scientific article published on 9 January 2018

Health status, emergency department visits, and oncologists' feedback: An analysis of secondary endpoints from a randomized phase II geriatric assessment trial

scientific article published in January 2019

Honorary and ghost authorship in reports of randomised clinical trials in oncology

scientific article published on 5 August 2016

How valid are claims for synergy in published clinical studies?

scientific article published on 07 February 2012

Human papillomavirus and host genetic polymorphisms in carcinogenesis: a systematic review and meta-analysis.

scientific article published on 07 August 2014

Hyperglycaemia and Survival in Solid Tumours: A Systematic Review and Meta-analysis.

scientific article published on 29 January 2018

Immune Therapy for Breast Cancer in 2010—Hype or Hope? ⬇️

scientific article published on January 1, 2011

Impact of Availability of Companion Diagnostics on the Clinical Development of Anticancer Drugs

scientific article published on 28 February 2017

Impact of Geographic Region on Benefit of Approved Anticancer Drugs Evaluated in International Phase III Clinical Trials

scientific article published on 2 November 2015

Impact of Granulocyte-colony Stimulating Factor on Bleomycin-induced Pneumonitis in Chemotherapy-treated Germ Cell Tumors

scientific article published on 4 September 2017

Impact of comorbidity on the outcome in men with advanced prostate cancer treated with docetaxel.

scientific article

Impact of high tumor mutational burden in solid tumors and challenges for biomarker application

scientific article published on 22 July 2020

Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer.

scientific article published on 24 November 2017

Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation

scientific article published on 01 July 2018

In silico analyses identify gene-sets, associated with clinical outcome in ovarian cancer: role of mitotic kinases.

scientific article published on 16 March 2016

Incidence of taxane-induced pain and distress in patients receiving chemotherapy for early-stage breast cancer: a retrospective, outcomes-based survey

scientific article

Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Review.

scientific article published on 7 December 2017

Influence of Competing Risks on Estimates of Recurrence Risk and Breast Cancer-specific Mortality in Analyses of the Early Breast Cancer Trialists Collaborative Group

scientific article published on 05 March 2020

Influence of censoring on conclusions of trials for women with metastatic breast cancer

scientific article

Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses

scientific article

Influence of control group therapy on the benefit from dose-dense chemotherapy in early breast cancer: a systemic review and meta-analysis.

scientific article published on 8 February 2018

Influence of non-measurable disease on progression-free survival in patients with metastatic breast cancer.

scientific article

Informative censoring - a neglected cause of bias in oncology trials

scientific article published on 09 April 2020

Integrin ανβ6 Protein Expression and Prognosis in Solid Tumors: A Meta-Analysis

scientific article published on 01 April 2020

Interaction between Hormonal Receptor Status, Age and Survival in Patients with BRCA1/2 Germline Mutations: A Systematic Review and Meta-Regression

scientific article

Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis

scientific article published on 26 December 2016

Irreversible pan-ErbB tyrosine kinase inhibitors and breast cancer: current status and future directions.

scientific article published on 04 September 2009

Is hormonal therapy effective in advanced endometrial cancer? A systematic review and meta-analysis.

scientific article

Is the neutrophil-to-lymphocyte ratio prognostic of survival outcomes in gynecologic cancers? A systematic review and meta-analysis.

scientific article published on 17 February 2017

Lapatinib and HER2 status: results of a meta-analysis of randomized phase III trials in metastatic breast cancer.

scientific article published on 25 January 2010

Lapatinib plus paclitaxel as first-line therapy for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: inappropriate conclusions from a company-sponsored study?

scientific article published on 2 March 2009

Large retroperitoneal lymphadenopathy and increased risk of venous thromboembolism in patients receiving first-line chemotherapy for metastatic germ cell tumors: A study by the global germ cell cancer group (G3)

scientific article published on 12 November 2019

Large retroperitoneal lymphadenopathy as a predictor of venous thromboembolism in patients with disseminated germ cell tumors treated with chemotherapy.

scientific article

Left Ventricular Dysfunction With Trastuzumab Therapy: Is Primary Prevention the Best Option?

scientific article published on 28 December 2016

Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration Based on Single-Arm Trials

scientific article published on 01 November 2018

Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration.

scientific article published on 13 December 2017

Management of small HER2 overexpressing tumours

scientific article published on 06 September 2012

Mechanisms and pathways of bone metastasis: challenges and pitfalls of performing molecular research on patient samples

scientific article

Medical oncology: Zoledronic acid for breast cancer therapy-induced bone loss

scientific article published in April 2010

Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis.

scientific article published on 04 April 2013

Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors.

scientific article published on March 2017

Modified Routine Cardiac Imaging Surveillance of Adult Cancer Patients and Survivors during the COVID-19 Pandemic

scientific article published on 16 April 2020

Multi-agent chemotherapy in advanced soft tissue sarcoma (STS) - A systematic review and meta-analysis

scientific article

Multidimensional challenges in clinical drug development, regulatory approval, and marketing.

scientific article published on 11 February 2013

National comprehensive cancer network recommendations for drugs without US food and drug administration approval in metastatic breast cancer: A cross-sectional study

scientific article published on 20 October 2020

Neuregulin expression in solid tumors: prognostic value and predictive role to anti-HER3 therapies

scientific article published on 08 April 2016

Neutrophil-to-lymphocyte ratio as a prognostic biomarker for men with metastatic castration-resistant prostate cancer receiving first-line chemotherapy: data from two randomized phase III trials.

scientific article

Neutrophil/lymphocyte ratio as a prognostic factor in biliary tract cancer

scientific article published on 11 March 2014

Oncogenic targets, magnitude of benefit, and market pricing of antineoplastic drugs

scientific article published on 23 May 2011

Oncologic Drugs Advisory Committee Recommendations and Approval of Cancer Drugs by the US Food and Drug Administration.

scientific article

One step forward, two steps back: The story of everolimus in advanced breast cancer.

scientific article

Optimisation of steroid prophylaxis schedules in breast cancer patients receiving docetaxel chemotherapy-a survey of health care providers and patients.

scientific article published on 3 May 2015

Optimising the use of bone-targeted agents in patients with metastatic cancers: a practical guide for medical oncologists

scientific article published on 22 July 2011

Outcome of adjuvant therapy in biliary tract cancers

scientific article published in August 2015

Outcomes of Estrogen Receptor Negative and Progesterone Receptor Positive Breast Cancer.

scientific article published on 10 July 2015

Outcomes of single versus double hormone receptor-positive breast cancer. A GEICAM/9906 sub-study

scientific article published on 21 March 2018

PD-L1 expression and clinical outcomes in patients with advanced urothelial carcinoma treated with checkpoint inhibitors: A meta-analysis

scientific article published on 16 May 2019

PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

scientific article published on 9 September 2015

Pathological complete response in breast cancer.

scientific article

Patient-Centered Cancer Drug Development: Clinical Trials, Regulatory Approval, and Value Assessment

scientific article published on 01 January 2019

Personalized medicine in immuno-oncology: a novel prognostic index in non-small cell lung cancer.

scientific article published in April 2018

Pharmacogenetic and Germline Prognostic Markers of Lung Cancer

article

Phase III trials of targeted anticancer therapies: redesigning the concept

scientific article published on 23 July 2013

Platinum-based chemotherapy in early-stage triple negative breast cancer: A meta-analysis

scientific article published on 28 August 2021

Poor correlation between progression-free and overall survival in modern clinical trials: are composite endpoints the answer?

scientific article published on 22 November 2011

Postmarketing Modifications of Drug Labels for Cancer Drugs Approved by the US Food and Drug Administration Between 2006 and 2016 With and Without Supporting Randomized Controlled Trials

scientific article published on 11 April 2018

Postmarketing Safety-Related Modifications of Drugs Approved by the US Food and Drug Administration Between 1999 and 2014 Without Randomized Controlled Trials

scientific article published on 01 January 2019

Predicting benefit from fulvestrant in pretreated metastatic breast cancer patients.

scientific article published on 24 June 2009

Prevalence of overt metastases in locally advanced breast cancer.

scientific article published on June 2008

Prevention, Detection, and Management of Chemotherapy-Related Cardiac Dysfunction

scientific article published on February 2016

Prognostic Value of Lymphocyte-Activation Gene 3 (LAG3) in Cancer: A Meta-Analysis

scientific article published on 15 October 2019

Prognostic relevance of receptor tyrosine kinase expression in breast cancer: a meta-analysis.

scientific article published on 3 September 2014

Prognostic role for the derived neutrophil-to-lymphocyte ratio in early breast cancer: a GEICAM/9906 substudy

scientific article published on 15 May 2018

Prognostic role of neutrophil-to-lymphocyte ratio in breast cancer: a systematic review and meta-analysis

scientific article published on 05 January 2017

Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis

scientific article

Prognostic role of platelet to lymphocyte ratio in solid tumors: a systematic review and meta-analysis

scientific article

Prognostic role of telomere length in malignancies: A meta-analysis and meta-regression

scientific article published on 12 May 2017

Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis

scientific article published on 29 May 2019

Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer

scientific article

Prostate cancer: Androgen deprivation therapy and bone loss

scientific article published on 01 December 2009

Radiological changes following second-line zoledronic acid treatment in breast cancer patients with bone metastases

scientific article published on 6 March 2009

Raising concern about the American Society of Clinical Oncology conflict of interest policy amendment

scientific article published on 4 August 2014

Randomized feasibility study of de-escalated (every 12 wk) versus standard (every 3 to 4 wk) intravenous pamidronate in women with low-risk bone metastases from breast cancer

scientific article

Refining Early Antitumoral Drug Development

article

Regional myocardial edema detected by T2 mapping is a feature of cardiotoxicity in breast cancer patients receiving sequential therapy with anthracyclines and trastuzumab.

scientific article published on 16 January 2014

Relevance of randomised controlled trials in oncology.

scientific article

Reply to L.A. Renfro et al

scientific article published on 01 November 2016

Reporting of Randomized Trials in Common Cancers in the Lay Media

scientific article published on 18 November 2017

Representation of Patients With Chronic Kidney Disease in Trials of Cancer Therapy

scientific article published on 01 June 2018

Response

Response

scientific article published in October 2018

Response to letter to the editor: The impact of the nodal status and resection margin on the effectiveness of adjuvant chemotherapy for pancreatic cancer: It calls for more careful evaluation

scientific article published on 30 August 2019

Response to: Assessing the risk of bias and publication bias should be integral parts of the systematic review

scientific article published on 02 July 2019

Rethinking end-points for bone-targeted therapy in advanced cancer

scientific article published on 11 June 2016

Right Ventricular Dysfunction in Patients Experiencing Cardiotoxicity during Breast Cancer Therapy

scientific article

Risk of incremental toxicities and associated costs of new anticancer drugs: a meta-analysis

scientific article published on 29 September 2014

Risk-Imaging Mismatch in Cardiac Imaging Practices for Women Receiving Systemic Therapy for Early-Stage Breast Cancer: A Population-Based Cohort Study

scientific article published on 23 May 2018

Role of Bisphosphonates in Breast Cancer Therapy

scientific article published on 14 March 2019

Role of cooperative groups and funding source in clinical trials supporting guidelines for systemic therapy of breast cancer.

scientific article

Second-line treatment in patients with advanced extra-pulmonary poorly differentiated neuroendocrine carcinoma: a systematic review and meta-analysis

scientific article published on 27 April 2020

Serial Cardiovascular Magnetic Resonance Strain Measurements to Identify Cardiotoxicity in Breast Cancer: Comparison With Echocardiography

scientific article published on 25 November 2020

Should a biopsy be recommended to confirm metastatic disease in women with breast cancer?

scientific article published in October 2009

Simple prognostic score for metastatic castration-resistant prostate cancer with incorporation of neutrophil-to-lymphocyte ratio.

scientific article published on 3 July 2014

Sorafenib as first-line therapy in patients with advanced Child-Pugh B hepatocellular carcinoma-a meta-analysis

scientific article published on 29 October 2018

Statin Exposure and Risk of Heart Failure After Anthracycline- or Trastuzumab-Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study

scientific article published on 06 January 2021

Statistical Considerations in Clinical Trial Design of Immunotherapeutic Cancer Agents

scientific article published on September 2015

Systemic therapy for non-clear cell renal cell carcinomas: a systematic review and meta-analysis

scientific article published on 02 June 2014

Targeting DNA repair in breast cancer: a clinical and translational update

scientific article published on 10 April 2010

Targeting the Epidermal Growth Factor Receptor in Addition to Chemotherapy in Patients with Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis

scientific article

The Effect of Exercise on Quality of Life, Fatigue, Physical Function, and Safety in Advanced Solid Tumor Cancers: A Meta-analysis of Randomized Control Trials

scientific article published on 15 July 2019

The Impact of Big Data Research on Practice, Policy, and Cancer Care

scientific article published on 01 January 2019

The Impact of Diabetes on Breast Cancer Treatments and Outcomes: A Population-Based Study.

scientific article published on 19 January 2018

The Price We Pay for Progress: A Meta-Analysis of Harms of Newly Approved Anticancer Drugs

scientific article published on 16 July 2012

The Risk of Heart Failure and Other Cardiovascular Hospitalizations After Early Stage Breast Cancer: A Matched Cohort Study

scientific article published on 01 August 2019

The Role of the 21-Gene Recurrence Score in Breast Cancer Treatment

scientific article published on 28 May 2016

The Voices of Young Women with Breast Cancer: Providing Support and Information for Improved Fertility Preservation Discussions

scientific article published on 03 June 2019

The Yield of Routine Cardiac Imaging in Breast Cancer Patients Receiving Trastuzumab-based Treatment: A Retrospective Cohort Study

scientific article published on 28 December 2019

The evolving landscape of protein kinases in breast cancer: clinical implications.

scientific article published on 15 June 2012

The risk of myocardial infarction with aromatase inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer.

scientific article published on 29 September 2016

The use of myocardial strain and newer echocardiography imaging techniques in cancer patients.

scientific article

Tissue confirmation of disease recurrence in breast cancer patients: pooled analysis of multi-centre, multi-disciplinary prospective studies.

scientific article

Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial.

scientific article

Toward Value-Based Pricing to Boost Cancer Research and Innovation

scientific article

Toxicity and clinical outcomes of partial breast irradiation compared to whole breast irradiation for early-stage breast cancer: a systematic review and meta-analysis

scientific article published on 30 March 2019

Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis

scientific article published in January 2018

Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: a systematic review and meta-analysis

scientific article published on 09 July 2011

Transcriptomic analyses identify association between mitotic kinases, PDZ-binding kinase and BUB1, and clinical outcome in breast cancer

scientific article published on 20 February 2016

Transcriptomic immunologic signature associated with favorable clinical outcome in basal-like breast tumors

scientific article

Translating clinical trials to clinical practice: outcomes of men with metastatic castration resistant prostate cancer treated with docetaxel and prednisone in and out of clinical trials.

scientific article published on 14 October 2013

Trastuzumab-Related Cardiotoxicity and Cardiac Care in Patients With HER2 Positive Metastatic Breast Cancer

scientific article published on 27 January 2020

Tumor necrosis and clinical outcomes following neoadjuvant therapy in soft tissue sarcoma: A systematic review and meta-analysis

scientific article published on 19 May 2018

Tumor-infiltrating lymphocytes in breast cancer: ready for prime time?

scientific article published on 9 March 2015

Ubiquitin-conjugating enzyme E2T (UBE2T) and denticleless protein homolog (DTL) are linked to poor outcome in breast and lung cancers.

scientific article published on 13 December 2017

Under-reporting of harm in clinical trials

scientific article published on 27 April 2016

Underestimation of risk by Gail model extends beyond women with atypical hyperplasia

scientific article published on 09 February 2009

Undisclosed Financial Conflicts of Interest of Authors of Clinical Drug Trials Published in Influential Medical Journals: A Cohort Study

scientific article published on 01 November 2019

Undisclosed financial conflicts of interest among authors of American Society of Clinical Oncology clinical practice guidelines

scientific article published on 29 July 2019

Update in treatment of early breast cancer in post-menopausal women

scientific article published on 18 April 2016

Variability in echocardiography and MRI for detection of cancer therapy cardiotoxicity

scientific article published on 25 February 2020

Vascular endothelial growth factor activity after switching of bisphosphonate treatment for metastatic breast cancer.

scientific article published in May 2009

Vascular endothelial growth factor pathway polymorphisms as prognostic and pharmacogenetic factors in cancer: a systematic review and meta-analysis

scientific article published on 25 June 2012

p53 Arg72Pro polymorphism, HPV status and initiation, progression, and development of cervical cancer: a systematic review and meta-analysis

scientific article

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