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List of works by Thomas Prebet

A new Leukemia Prognostic Scoring System for refractory/relapsed adult acute myelogeneous leukaemia patients: a GOELAMS study

scientific article published on 18 February 2011

A phase 1 trial of the anti-inhibitory KIR mAb IPH2101 for AML in complete remission

scientific article published on 21 September 2012

A phase I/II trial of Erlotinib in higher risk myelodysplastic syndromes and acute myeloid leukemia after azacitidine failure

scientific article published on 7 October 2014

A phase II study of intensive chemotherapy with fludarabine, cytarabine, and mitoxantrone in P glycoprotein-negative high-risk myelodysplastic syndromes

scientific article

A phase Ib GOELAMS study of the mTOR inhibitor RAD001 in association with chemotherapy for AML patients in first relapse.

scientific article published on 16 January 2013

A randomized phase II trial of azacitidine +/- epoetin-β in lower-risk myelodysplastic syndromes resistant to erythropoietic stimulating agents

scientific article published on 26 May 2016

A simplified, 96-well-adapted, ATP luminescence-based motility assay

scientific article published in October 2009

Acute myeloid leukemia with translocation (8;21) or inversion (16) in elderly patients treated with conventional chemotherapy: a collaborative study of the French CBF-AML intergroup

scientific article published on 31 August 2009

Addition of suberoylanilide hydroxamic acid (Vorinostat) to azacitidine for patients with higher risk myelodysplastic syndromes and azacitidine failure: a phase II add-on study from the Groupe Francophone des Myelodysplasies

scientific article

Allogeneic hematopoietic SCT and mechanical heart valve: feasibility of reduced toxicity myeloablative conditioning

scientific article published on 22 February 2010

Allogeneic hematopoietic cell transplantation following the use of hypomethylating agents among patients with relapsed or refractory AML: Findings from an international retrospective study.

scientific article published on 9 April 2018

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia ⬇️

scientific article published on 13 June 2016

Anthracycline dose intensification improves molecular response and outcome of patients treated for core binding factor acute myeloid leukemia

scientific article published on 27 June 2014

Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.

scientific article published on 7 October 2011

Autologous hematopoietic stem cell transplantation for adults with acute myeloid leukemia in complete remission: the Edouard Herriot Hospital experience

scientific article published on 01 June 2006

Azacitidine for the treatment of relapsed and refractory AML in older patients

scientific article published on 24 November 2014

Azacitidine treatment for patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 3q abnormalities

scientific article published on 25 June 2015

Azacitidine with or without Entinostat for the treatment of therapy-related myeloid neoplasm: further results of the E1905 North American Leukemia Intergroup study.

scientific article published on 18 November 2015

BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.

scientific article

Can the revised IPSS predict response to erythropoietic-stimulating agents in patients with classical IPSS low or intermediate-1 MDS?

scientific article published in September 2013

Cancer-Induced Alterations of NK-Mediated Target Recognition: Current and Investigational Pharmacological Strategies Aiming at Restoring NK-Mediated Anti-Tumor Activity

scientific article published on 24 March 2014

Chronic myelomoncytic leukemia: Are we finally solving the identity crisis?

scientific article published on 25 April 2016

Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study.

scientific article published on 14 April 2017

Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes

scientific article published on 25 July 2017

Combination of cytarabine and topotecan in patients treated for acute myeloid leukemia with persistent disease after frontline induction

scientific article published on 07 August 2012

Combination of vorinostat and low dose cytarabine for patients with azacitidine-refractory/relapsed high risk myelodysplastic syndromes

scientific article

Comparative clinical effectiveness of azacitidine versus decitabine in older patients with myelodysplastic syndromes

scientific article published on 21 September 2016

Comparison of 60 or 90 mg/m(2) of daunorubicin in induction therapy for acute myeloid leukemia with intermediate or unfavorable cytogenetics

scientific article published on 19 November 2014

Concomitant germ-line RUNX1 and acquired ASXL1 mutations in a T-cell acute lymphoblastic leukemia.

scientific article published on 28 June 2013

Core-binding factor acute myeloid leukemia in first relapse: a retrospective study from the French AML Intergroup

scientific article published on 08 July 2014

Daily practice management of myelodysplastic syndromes in France: data from 907 patients in a one-week cross-sectional study by the Groupe Francophone des Myelodysplasies

scientific article

Dasatinib in high-risk core binding factor acute myeloid leukemia in first complete remission: a French Acute Myeloid Leukemia Intergroup trial.

scientific article published on 24 February 2015

Drug response profiling can predict response to ponatinib in a patient with t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia

scientific article published on 13 March 2015

Efficacy and safety of lenalidomide in intermediate-2 or high-risk myelodysplastic syndromes with 5q deletion: results of a phase 2 study

scientific article published on 5 November 2008

Emerging treatment options for patients with high-risk myelodysplastic syndrome

scientific article published on 11 November 2020

Evaluation of comorbidity indexes in the outcome of elderly patients treated for acute lymphoblastic leukemia

scientific article published on 28 January 2014

Extensive chronic GVHD is associated with donor blood CD34+ cell count after G-CSF mobilization in non-myeloablative allogeneic PBSC transplantation

scientific article published on 21 May 2012

Gene mutations differently impact the prognosis of the myelodysplastic and myeloproliferative classes of chronic myelomonocytic leukemia

article

High dose cyclophosphamide for cytoreduction in patients with acute myeloid leukemia with hyperleukocytosis or leukostasis

scientific article published on 16 December 2020

Histone méthyltransférases

article from 2011

Hypomethylating agent based combinations in higher risk myelodysplastic syndrome

scientific article published on 09 December 2019

Hypomethylating agent combination strategies in myelodysplastic syndromes: hopes and shortcomings

scientific article published on 21 September 2016

Hypomethylating agents (HMA) treatment for myelodysplastic syndromes: alternatives in the frontline and relapse settings

scientific article published on 4 July 2017

Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort

scientific article published on 01 April 2018

Impact of baseline cytogenetic findings and cytogenetic response on outcome of high-risk myelodysplastic syndromes and low blast count AML treated with azacitidine

scientific article

Impact of reduced-intensity conditioning allogeneic stem cell transplantation on women's fertility.

scientific article published on 24 September 2013

Improved outcome of patients with low- and intermediate-risk cytogenetics acute myeloid leukemia (AML) in first relapse with gemtuzumab and cytarabine versus cytarabine: results of a retrospective comparative study

scientific article published on 18 October 2010

Incidence of 17p deletions and TP53 mutation in myelodysplastic syndrome and acute myeloid leukemia with 5q deletion

scientific article published on 30 August 2012

Incidence of ATRX mutations in myelodysplastic syndromes, the value of microcytosis.

scientific article

Influence of NPM1 and FLT3-ITD status on outcome in relapsed/refractory AML patients receiving salvage therapy including gemtuzumab ozogamicin.

scientific article

Insights into novel emerging epigenetic drugs in myeloid malignancies

scientific article published on 06 August 2019

Lenalidomide in lower-risk myelodysplastic syndromes with karyotypes other than deletion 5q and refractory to erythropoiesis-stimulating agents

scientific article published on 23 December 2011

Lenalidomide treatment for patients with myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure

scientific article published on 29 November 2012

Lost in translation? Ten years of development of histone deacetylase inhibitors in acute myeloid leukemia and myelodysplastic syndromes

scientific article

Minimizing risk of hypomethylating agent failure in patients with higher-risk MDS and practical management recommendations

scientific article

Modest improvement in survival of patients with refractory anemia with excess blasts in the hypomethylating agents era in the United States

scientific article published on 25 August 2016

Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes.

scientific article

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

scientific article published on 15 April 2009

New Insights into the Pathogenesis of MDS and the rational therapeutic opportunities

scientific article

Outcome of High-Risk Myelodysplastic Syndrome After Azacitidine Treatment Failure ⬇️

scientific article published on July 25, 2011

Outcome of acute myeloid leukaemia following myelodysplastic syndrome after azacitidine treatment failure.

scientific article published on 06 March 2012

Outcome of patients with low-risk myelodysplasia after azacitidine treatment failure

scientific article published on 14 September 2012

Outcome of relapse after allogeneic stem cell transplant in patients with acute myeloid leukemia

scientific article

Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer

scientific article published on 11 May 2015

PICALM-MLLT10 acute myeloid leukemia: a French cohort of 18 patients

scientific article

PTK7: a cell polarity receptor with multiple facets

scientific article published on 15 April 2011

Patterns of Venous Thromboembolism Prophylaxis During Treatment of Acute Leukemia: Results of a North American Web-Based Survey

scientific article

PcG methylation of the HIST1 cluster defines an epigenetic marker of acute myeloid leukemia

scientific article published on 8 December 2014

Pegylated IFN-α2a combined to imatinib mesylate 600mg daily can induce complete cytogenetic and molecular responses in a subset of chronic phase CML patients refractory to IFN alone or to imatinib 600mg daily alone

scientific article published on 03 June 2010

Performance of the Medical Research Council (MRC) and the Leukemia Research Foundation (LRF) score in predicting survival benefit with hypomethylating agent use in patients with relapsed or refractory acute myeloid leukemia

scientific article published on 02 July 2018

Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia

scientific article

Phase I and pharmacokinetic study of elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies

scientific article published on 06 January 2012

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia

scientific article published on 11 April 2016

Planctomycetes DNA in febrile aplastic patients with leukemia, rash, diarrhea, and micronodular pneumonia

scientific article

Platelet recovery and transfusion needs after reduced intensity conditioning allogeneic peripheral blood stem cell transplantation

scientific article published on 01 January 2010

Poor outcome with nonmyeloablative conditioning regimen before cord blood transplantation for patients with high-risk acute myeloid leukemia compared with matched related or unrelated donor transplantation

scientific article published on 14 June 2014

Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia

scientific article published on 28 April 2011

Predicting outcome of patients with myelodysplastic syndromes after failure of azacitidine: validation of the North American MDS consortium scoring system

scientific article published on October 2016

Predictive factors for outcomes after reduced intensity conditioning hematopoietic stem cell transplantation for hematological malignancies: a 10-year retrospective analysis from the Société Française de Greffe de Moelle et de Thérapie Cellulaire

scientific article

Presence of a minor Philadelphia-positive clone in young adults with de novo T-cell ALL

scientific article published on 01 March 2009

Prior treatment with gemtuzumab ozogamicin and the risk of veno-occlusive disease after allogeneic haematopoietic stem cell transplantation

scientific article published on 06 July 2009

Prognostic significance of myelodysplasia-related changes according to the WHO classification among ELN-intermediate-risk AML patients

scientific article published on 18 October 2014

Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.

scientific article published on 24 March 2014

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

scientific article

Reduced-intensity conditioning with Fludarabin, oral Busulfan, and thymoglobulin allows long-term disease control and low transplant-related mortality in patients with hematological malignancies

scientific article published on 17 September 2010

Risk stratification in myelodysplastic syndromes: is there a role for gene expression profiling?

scientific article

Secondary Philadelphia chromosome after non-myeloablative peripheral blood stem cell transplantation for a myelodysplastic syndrome in transformation

scientific article published on 01 January 2004

Single agent blinatumumab as frontline therapy for an 85-year-old patient with B cell precursor acute lymphoblastic leukemia

scientific article published on 29 July 2016

Sotatercept with long-term extension for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes: a phase 2, dose-ranging trial

scientific article published on 10 January 2018

Systemic learning planification for medical students during oncology clinical rotation

scientific article published in December 2011

The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome

scientific article published on 17 June 2010

The increase from 2.5 to 5 mg/kg of rabbit anti-thymocyte-globulin dose in reduced intensity conditioning reduces acute and chronic GVHD for patients with myeloid malignancies undergoing allo-SCT

scientific article published on 06 February 2012

Trends in Clinical Investigation for Myelodysplastic Syndromes

scientific article published on August 2016

Tumor cell contamination in ovarian tissue cryopreserved before gonadotoxic treatment: should we systematically exclude ovarian autograft in a cancer survivor?

scientific article published on 16 November 2009

Validation of a post-hypomethylating agent failure prognostic model in myelodysplastic syndromes patients treated in a randomized controlled phase III trial of rigosertib vs. best supportive care

scientific article published on 14 December 2017

Vorinostat in acute myeloid leukemia and myelodysplastic syndromes

scientific article published on 31 December 2010

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