List of works - Sayyed K. Zaidi

A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation

scientific article

A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation

scientific article published on 30 June 2013

Alterations in intranuclear localization of Runx2 affect biological activity

scientific article published on December 2006

Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network

scientific article

An architectural genetic and epigenetic perspective

scientific article published on 24 December 2010

An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.

scientific article published on December 2006

Analysis of in vivo gene expression using epitope-tagged proteins

scientific article published on 01 January 2004

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information

scientific article

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments

scientific article

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

scientific article published on 09 January 2014

Bookmarking the genome: maintenance of epigenetic information.

scientific article

Chromatin immunoprecipitation

scientific article published on 01 January 2004

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

scientific article

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

scientific article

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

scientific article

Epigenetic mechanisms in leukemia

scientific article published on 24 May 2012

Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity

scientific article published on 03 July 2018

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

scientific article published on November 2003

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

scientific article published on August 2008

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells

scientific article published on 17 April 2015

HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

scientific article

Identification of HiNF-P, a Key Activator of Cell Cycle-Controlled Histone H4 Genes at the Onset of S Phase ⬇️

scientific article published on November 1, 2003

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

scientific article

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

In situ nuclear organization of regulatory machinery

scientific article published on 01 January 2008

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

scientific article

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

scientific article (publication date: 23 July 2004)

Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

scientific article

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

scientific article

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

scientific article

Mitotic bookmarking of genes: a novel dimension to epigenetic control.

scientific article

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

scientific article

Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells

scientific journal article

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

scholarly article

Nuclear microenvironments and cancer

scientific article published on 01 August 2008

Nuclear microenvironments in biological control and cancer.

scientific article published on June 2007

Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells

scientific article published on August 2013

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

scientific article published on 23 March 2007

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

scientific article published on February 2009

Phenotypic transcription factors epigenetically mediate cell growth control.

scholarly article

Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.

scientific article

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

scientific article published on January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

scientific article published on 01 January 2004

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

scientific article published on 14 September 2004

RUNX1-dependent mechanisms in biological control and dysregulation in cancer

scientific article published on 04 December 2018

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

scientific article

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

scientific article published on May 2004

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

scholarly article

Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

scientific article published on October 2008

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

scientific article

Subnuclear localization and intranuclear trafficking of transcription factors

scientific article published on January 2010

Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

scientific article published on 03 July 2001

Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.

scientific article

The abbreviated pluripotent cell cycle.

scientific article published on January 2013

The architectural organization of human stem cell cycle regulatory machinery

scientific journal article

The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

scientific article published on June 2014

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

scientific article

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif

scientific article

The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.

scientific article

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer

scientific article

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

scientific article published on February 2009

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes

scientific article

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

scientific article published on 12 February 2004

List of works by Sayyed K. Zaidi

A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation

A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation

Alterations in intranuclear localization of Runx2 affect biological activity

Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network

An architectural genetic and epigenetic perspective

An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.

Analysis of in vivo gene expression using epitope-tagged proteins

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

Bookmarking the genome: maintenance of epigenetic information.

Chromatin immunoprecipitation

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

Epigenetic mechanisms in leukemia

Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells

HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

Identification of HiNF-P, a Key Activator of Cell Cycle-Controlled Histone H4 Genes at the Onset of S Phase ⬇️

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

In situ immunofluorescence analysis: immunofluorescence microscopy

In situ nuclear organization of regulatory machinery

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

Mitotic bookmarking of genes: a novel dimension to epigenetic control.

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

Nuclear microenvironments and cancer

Nuclear microenvironments in biological control and cancer.

Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

Phenotypic transcription factors epigenetically mediate cell growth control.

Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

RUNX1-dependent mechanisms in biological control and dysregulation in cancer

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

Subnuclear localization and intranuclear trafficking of transcription factors

Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.

The abbreviated pluripotent cell cycle.

The architectural organization of human stem cell cycle regulatory machinery

The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif

The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription