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List of works by Geraldo A. Passos

A Crispr-Cas9 System Designed to Introduce Point Mutations into the Human <em>ACE2</em> Gene to Weaken the Interaction of the ACE2 Receptor with the SARS-CoV-2 S Protein<strong> </strong>

A transcript finishing initiative for closing gaps in the human transcriptome

scientific article

Abnormal T-Cell Development in the Thymus of Non-obese Diabetic Mice: Possible Relationship With the Pathogenesis of Type 1 Autoimmune Diabetes

scientific article published on 12 July 2018

Adhesion between medullary thymic epithelial cells and thymocytes is regulated by miR-181b-5p and miR-30b

scientific article published on 26 September 2019

Affected and non-affected skin fibroblasts from systemic sclerosis patients share a gene expression profile deviated from the one observed in healthy individuals.

scientific article published on September 2008

Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1).

scientific article published on 23 April 2010

Aire Disruption Influences the Medullary Thymic Epithelial Cell Transcriptome and Interaction With Thymocytes.

scientific article

Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells

scientific article

Aire Gene Influences the Length of the 3' UTR of mRNAs in Medullary Thymic Epithelial Cells

scientific article published on 28 May 2020

Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction

scientific article published on 27 August 2014

Alterations in gene expression profiles correlated with cisplatin cytotoxicity in the glioma U343 cell line ⬇️

scientific article

Assessment of DNA damage and mRNA/miRNA transcriptional expression profiles in hyperglycemic versus non-hyperglycemic patients with type 2 diabetes mellitus

scientific article

Association between EcoRI fragment-length polymorphism of the immunoglobulin lambda variable 8 (IGLV8) gene family with rheumatoid arthritis and systemic lupus erythematosus

scientific article published on April 2001

Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells

scientific article

Autoimmune regulator act in synergism with thymocyte adhesion in the control of lncRNAs in medullary thymic epithelial cells

Autoimmune regulator act in synergism with thymocyte adhesion in the control of lncRNAs in medullary thymic epithelial cells

Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes

scientific article

Cell organisation, sulphur metabolism and ion transport-related genes are differentially expressed in Paracoccidioides brasiliensis mycelium and yeast cells

scientific article

Changes in the gene expression profiling of the thymus in response to fibrosarcoma growth

article

Chromosomal location of the human immunoglobulin lambda variable 8 (IGLV8) gene family outside the major lambda locus on chromosome 22q11.2.

scientific article published in December 1997

Chromosomal rearrangements involving telomeric DNA sequences in Balb/3T3 cells transfected with the Ha-ras oncogene.

scientific article

Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis

scholarly article

Cisplatin associated with LY294002 increases cytotoxicity and induces changes in transcript profiles of glioblastoma cells.

scientific article published on 12 November 2013

Collagen induced arthritis (CIA) in mice features regulatory transcriptional network connecting major histocompatibility complex (MHC H2) with autoantigen genes in the thymus

article

Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

scientific article published on 25 November 2015

Comprehensive gene expression profiling in lungs of mice infected with Mycobacterium tuberculosis following DNAhsp65 immunotherapy.

scientific article

Correction: T Cell Post-Transcriptional miRNA-mRNA Interaction Networks Identify Targets Associated with Susceptibility/Resistance to Collagen-induced Arthritis.

correction of a scientific article

Definition of a sequence-tagged site for the human immunoglobulin IGLV9S1 gene located at chromosome 22q11

article

Delayed effects of exposure to a moderate radiation dose on transcription profiles in human primary fibroblasts

scientific article published on March 2011

Development of type 1 diabetes mellitus in nonobese diabetic mice follows changes in thymocyte and peripheral T lymphocyte transcriptional activity

scientific article

Differential gene expression in gamma-irradiated BALB/3T3 fibroblasts under the influence of 3-aminobenzamide, an inhibitior of parp enzyme.

scientific article

Differential gene expression of peripheral blood mononuclear cells from rheumatoid arthritis patients may discriminate immunogenetic, pathogenic and treatment features

scientific article

Differential gene expression profiles may differentiate responder and nonresponder patients with rheumatoid arthritis for methotrexate (MTX) monotherapy and MTX plus tumor necrosis factor inhibitor combined therapy

scientific article

Differential transcript profiles of MHC class Ib(Qa-1, Qa-2, and Qa-10) and Aire genes during the ontogeny of thymus and other tissues

scientific article

Early transcriptional response of Paracoccidioides brasiliensis upon internalization by murine macrophages

article

Editorial: The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance

scientific article published on 14 December 2015

Effect of cell source and osteoblast differentiation on gene expression profiles of mesenchymal stem cells derived from bone marrow or adipose tissue

scientific article published on 11 February 2019

Emergence of TCR alpha/beta V(D)J recombination and transcription during ontogeny of inbred mouse strains

scientific article published on 01 October 1998

Evidence for a network transcriptional control of promiscuous gene expression in medullary thymic epithelial cells

scientific article

Expression of genes related to apoptosis, cell cycle and signaling pathways are independent of TP53 status in urinary bladder cancer cells

scientific article published on 30 November 2010

Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire).

scientific article published on 14 February 2012

Frequency of the delta ccr5 deletion allele in the urban Brazilian population

scientific article published on April 1998

Gene Expression Profiles in Human Lymphocytes IrradiatedIn Vitrowith Low Doses of Gamma Rays

article

Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease

article

Gene expression profiles in human cells submitted to genotoxic stress

scientific article published on November 2003

Gene expression profiles in radiation workers occupationally exposed to ionizing radiation.

scientific article

Gene expression profiles stratified according to type 1 diabetes mellitus susceptibility regions

scientific article

Gene expression profiling during thymus ontogeny and its association with TCRVbeta8.1-Dbeta2.1 rearrangements of inbred mouse strains

scientific article published in October 2003

Genes that code for T cell signaling proteins establish transcriptional regulatory networks during thymus ontogeny

scientific article

Genetic Susceptibility Loci in Rheumatoid Arthritis Establish Transcriptional Regulatory Networks with Other Genes

article

Genomic EcoRI polymorphism and cosmid sequencing reveal an insertion/deletion and a new IGLV5 allele in the human immunoglobulin lambda variable locus (22q11.2/IGLV).

scientific article published on 29 March 2003

Hybridization signatures during thymus ontogeny reveals modulation of genes coding for T-cell signaling proteins

scientific article

Hybridization signatures of gamma-irradiated murine fetal thymus organ culture (FTOC) reveal modulation of genes associated with T-cell receptor V(D)J recombination and DNA repair

article

Identification of Cell-Free Circulating MicroRNAs for the Detection of Early Breast Cancer and Molecular Subtyping

scientific article published on 08 August 2019

Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients

scientific article

Immunoglobulin V-lambda transcription profiling of systemic lupus erythematosus patients reveals biased usage of genes located near the Jlambda-Clambda segments

scientific article published in April 2004

Immunological memory for HIV-1 induced in rabbits by immune poly(A)+ RNA.

scientific article published in January 1991

In vivo induction of immunological memory to human tumor extract with poly (A)-containing immune RNA

scientific article published on 01 January 1988

Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation

scientific article

Ionizing radiation-induced gene expression changes in TP53 proficient and deficient glioblastoma cell lines

scientific article published on 29 June 2013

Is HLA class II profile relevant for the study of large-scale differentially expressed genes in type 1 diabetes mellitus patients?

scientific article published in October 2006

Large scale gene expression analysis of CBA/J mouse strain fetal thymus using cDNA-array hybridizations.

scientific article published in May 2004

Metabolism genes are among the differentially expressed ones observed in lymphomononuclear cells of recently diagnosed type 1 diabetes mellitus patients.

scientific article

MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus

article

MicroRNAs from peripheral blood mononuclear cells as biomarkers for detection of preclinical fibrosarcoma

scientific article published on 4 April 2013

Microarray-based gene expression analysis of human osteoblasts in response to different biomaterials.

scientific article published in February 2009

Murine dendritic cells transcriptional modulation upon Paracoccidioides brasiliensis infection.

scientific article

Novel Dual AChE and ROCK2 Inhibitor Induces Neurogenesis via PTEN/AKT Pathway in Alzheimer’s Disease Model

scientific article published in 2022

Occurrence of TRGV-BJ hybrid gene in SV40-transformed fibroblast cell lines.

scientific article

One-week intervention period led to improvements in glycemic control and reduction in DNA damage levels in patients with type 2 diabetes mellitus

scientific article published on 21 June 2014

Onset of T-cell receptor Vβ8.1 and Dβ2.1 V(D)J recombination during thymus development of inbred mouse strains

article

Onset of promiscuous gene expression in murine fetal thymus organ culture.

scientific article published on 10 August 2006

Oxidative Nanopatterning of Titanium Surface Influences mRNA and MicroRNA Expression in Human Alveolar Bone Osteoblastic Cells

scientific article (publication date: 2016)

P102

scholarly article by Eduardo A. Donadi et al published October 2014 in Human Immunology

Post-transcriptional markers associated with clinical complications in Type 1 and Type 2 diabetes mellitus

scientific article published on 26 March 2019

Posttranscriptional Interaction Between miR-450a-5p and miR-28-5p and STAT1 mRNA Triggers Osteoblastic Differentiation of Human Mesenchymal Stem Cells

scientific article published on 13 April 2017

Predicted miRNA-mRNA-mediated posttranscriptional control associated with differences in cervical and thoracic thymus function

scientific article published on 26 May 2018

Profiling Meta-Analysis Reveals Primarily Gene Coexpression Concordance between Systemic Lupus Erythematosus and Rheumatoid Arthritis

article

Promiscuous gene expression in the thymus: the root of central tolerance.

scientific article published on June 2006

RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion

scientific article

RNA-mediated genetic transformation in Aspergillus nidulans

scientific article published on 01 January 1989

Recurrent 22q11.2 deletion in a sibship suggestive of parental germline mosaicism in velocardiofacial syndrome

scientific article published in May 2002

Repopulation of a 3D-simulated periapical lesion cavity with triggered osteoblastic-differentiated dental pulp stem cell spheroids

Shared and unique gene expression in systemic lupus erythematosus depending on disease activity

scientific article published in September 2009

Systemic lupus erythematosus patients under immunosuppressive treatment express high levels of the immunoglobulin lambda variable IGLV8S1 gene with silent somatic mutations

scientific article published in January 2002

T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis

scientific article (publication date: 2013)

TNFa-e Microsatellite, HLA-DRB1 and -DQB1 Alleles and Haplotypes in Brazilian Patients Presenting Recently Diagnosed Type 1 Diabetes Mellitus

article

The AIRE G228W mutation disturbs the interaction of AIRE with its partner molecule SIRT1

The AIRE G228W mutation disturbs the interaction of AIRE with its partner molecule SIRT1

The Autoimmune Regulator (Aire) transactivates HLA-G gene expression in thymic epithelial cells

scientific article published on 19 August 2019

The Effect of TAK-778 on Gene Expression of Osteoblastic Cells Is Mediated Through Estrogen Receptor

article

The Impact of Transcriptomics on the Fight against Tuberculosis: Focus on Biomarkers, BCG Vaccination, and Immunotherapy ⬇️

scientific article published on December 20, 2010

The Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central Tolerance

scientific article (publication date: 2015)

The high infectivity of SARS-CoV-2 B.1.1.7 is associated with increased interaction force between Spike-ACE2 caused by the viral N501Y mutation

The human immunoglobulin variable lambda locus IGLV9 gene is a monomorphic marker in the urban Brazilian population

scientific article published on September 1999

Time course of c-fos, vasopressin and oxytocin mRNA expression in the hypothalamus following long-term dehydration.

scientific article

Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism

scientific article published on 22 May 2019

Transcript Expression Profiles and MicroRNA Regulation Indicate an Upregulation of Processes Linked to Oxidative Stress, DNA Repair, Cell Death, and Inflammation in Type 1 Diabetes Mellitus Patients

scientific article published on 01 February 2022

Transcription profiling of Prss16 (Tssp) can be used to find additional peptidase genes that are candidates for self-peptide generation in the thymus.

scientific article

Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiation

scientific article published on December 2008

Transcriptional profiles of the human pathogenic fungus Paracoccidioides brasiliensis in mycelium and yeast cells.

scientific article

Transcriptional response of murine macrophages upon infection with opsonized Paracoccidioides brasiliensis yeast cells

article

Transcriptional response of peripheral lymphocytes to early fibrosarcoma: a model system for cancer detection based on hybridization signatures

scientific article

Transcriptome Analysis During Normal Human Mesenchymal Stem Cell Differentiation

Transcriptome meta-analysis of peripheral lymphomononuclear cells indicates that gestational diabetes is closer to type 1 diabetes than to type 2 diabetes mellitus

scientific article published on 09 May 2013

Typical phenotypic spectrum of velocardiofacial syndrome occurs independently of deletion size in chromosome 22q11.2.

scientific article

Undifferentiated pulp cells and odontoblast-like cells share genes involved in the process of odontogenesis

scientific article

Update on Aire and thymic negative selection

scientific article published on 4 September 2017

Using cDNA microarrays to identify human CD19(+) B cell gene products (ESTs) originated from systemic lupus erythematosus susceptibility loci.

scientific article published on 6 January 2006

cDNA microarray analysis of cyclosporin A (CsA)-treated human peripheral blood mononuclear cells reveal modulation of genes associated with apoptosis, cell-cycle regulation and DNA repair

scientific article published on 30 May 2007

miR-155 exerts posttranscriptional control of autoimmune regulator (Aire) and tissue-restricted antigen genes in medullary thymic epithelial cells

scientific article published on 28 May 2022

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