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List of works by Kazuya Shinmura

8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity

scientific article published on 01 October 1997

A novel APC mosaicism in a patient with familial adenomatous polyposis

scientific article published on 10 December 2015

A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.

scientific article

A novel somatic FGFR3 mutation in primary lung cancer

scientific article

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.

scientific article

A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion

scientific article published on 02 May 2011

A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair genes results in reduced translation efficiency of its transcripts

scientific article

Aberrant expression and mutation-inducing activity of AID in human lung cancer.

scientific article

Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

scientific article published on 3 March 2016

Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4.

scientific article

Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer

scientific journal article

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

scientific article

Altered expression of the human base excision repair gene NTH1 in gastric cancer

scientific article published on 4 May 2009

Anaplastic changes of diffuse leptomeningeal glioneuronal tumor with polar spongioblastoma pattern

scientific article published on 26 July 2018

Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.

scientific article published in December 2007

Association between dopamine beta hydroxylase rs5320 polymorphism and smoking behaviour in elderly Japanese

scientific article

Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population

scientific article

Association between neurexin 1 (NRXN1) polymorphisms and the smoking behavior of elderly Japanese

scientific article published on 01 June 2010

Association between neuropeptide Y receptor 2 polymorphism and the smoking behavior of elderly Japanese

scientific article published on 2 September 2010

BSND and ATP6V1G3: Novel Immunohistochemical Markers for Chromophobe Renal Cell Carcinoma

scientific article published on June 2015

BSND is a Novel Immunohistochemical Marker for Oncocytic Salivary Gland Tumors

scientific article published on 3 May 2017

CD44-SLC1A2 fusion transcripts in primary colorectal cancer

scientific article

CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma

scientific article

CLCA2 as a novel immunohistochemical marker for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the lung

scientific article

Causation of Borrmann type 4 gastric cancer: heritable factors or environmental factors?

scientific article published on 01 January 2003

Characterization of V-set and immunoglobulin domain containing 1 exerting a tumor suppressor function in gastric, lung, and esophageal cancer cells.

scientific article

Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient.

scientific article published in November 2008

Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity

scientific journal article

Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH)

scientific article published on 01 November 2012

Clinical analysis of false-negative fine needle aspiration cytology of head and neck cancers

scientific article published on 17 December 2018

Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

scientific article published on April 2016

Clinicopathological and Survival Analysis of Japanese Patients with Resected Non-Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification

scientific article published on November 2015

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

scientific article

Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5-hydroxyuracil, an oxidation product of cytosine

scientific article published on 12 December 2018

Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization.

scientific article

Detection of lipid peroxidation-induced DNA adducts caused by 4-oxo-2(E)-nonenal and 4-oxo-2(E)-hexenal in human autopsy tissues

scientific article published on September 2010

Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication

scientific article published on 30 October 2006

Distinct prognostic roles and heterogeneity of TTF1 copy number and TTF1 protein expression in non-small cell lung cancer.

scientific article published on 5 April 2017

Downregulation of EphA7 by hypermethylation in colorectal cancer

scientific article published on August 2005

E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer

scientific article published on 01 October 2002

EML4-ALK fusion transcripts in immunohistochemically ALK-positive non-small cell lung carcinomas.

scientific article

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas

scientific article

EPH-EPHRIN in human gastrointestinal cancers

scientific article published on December 2010

EPHA2/EFNA1 expression in human gastric cancer.

scientific article

Effect of boron neutron capture therapy for recurrent anaplastic meningioma: an autopsy case report

scientific article published on 8 May 2014

Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression

scientific article published in August 2005

Enhancement of OGG1 protein AP lyase activity by increase of APEX protein

scientific article published on June 2001

Familial gastric cancer: clinicopathological characteristics, RER phenotype and germline p53 and E-cadherin mutations

scientific article published in June 1999

Fluorescence-labeled methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP) analysis for quantitative determination of DNA methylation and demethylation status

scientific article

Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.

scientific article published on 9 April 2016

Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach

scientific article published on 01 December 1995

Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population

scientific article published on 23 December 2015

Genes Located on 18q23 Are Epigenetic Markers and Have Prognostic Significance for Patients with Head and Neck Cancer

article

Genes encoding neuropeptide receptors are epigenetic markers in patients with head and neck cancer: a site-specific analysis.

scientific article published on 18 July 2017

Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population

scientific article

Germline p53 mutation in a patient with multiple primary cancers

scientific article published on 01 July 2001

Heterogeneity analysis of PD-L1 expression and copy number status in EBUS-TBNA biopsy specimens of non-small cell lung cancer: Comparative assessment of primary and metastatic sites

scientific article published on 05 June 2019

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts.

scientific article published on 20 August 2014

Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer

scientific article

Identification and association study with lung cancer for novel insertion polymorphisms of human endogenous retrovirus

scientific article published on 19 July 2013

Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population

scientific article published on 8 August 2007

Identification and characterization of a novel germline p53 mutation in a patient with glioblastoma and colon cancer

scientific article published in August 2009

Identification of 5 novel germline APC mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis

scientific article

Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer

scientific article published in January 2003

Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer

scientific article published on 23 March 2014

Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis

scientific article published on December 2012

Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer

scientific article

Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE).

scientific article

Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma

scientific article published on 01 November 2008

Lipid peroxidation-induced DNA adducts in human gastric mucosa

scientific article

Mediastinal mature teratoma with complete gastrointestinal and bronchial walls

scientific article published on 24 May 2015

Mesothelial/monocytic incidental cardiac excrescence with bone marrow.

scientific article

Microsatellite instability and K-ras mutations in gastric adenomas, with reference to associated gastric cancers

scientific article published on 01 January 1999

Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells

scientific article published on 30 September 2017

NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations

scientific article

Neoadjuvant imatinib treatment and laparoscopic anus-preserving surgery for a large gastrointestinal stromal tumor of the rectum

scientific article published on 8 March 2016

Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation

scientific article

OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells

scientific article

OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa

scientific article

POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma

scientific article

Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer

scientific article published on 02 January 2017

Promoter methylation of galanin receptors as epigenetic biomarkers for head and neck squamous cell carcinomas

scientific article published on 21 January 2019

RER phenotype and its associated mutations in familial gastric cancer

scientific article published on 01 February 1998

RSPO fusion transcripts in colorectal cancer in Japanese population

scientific article

Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer

scientific article

Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer

scientific article published on 07 August 2014

SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer

scientific article

Site-specific methylation patterns of the GAL and GALR1/2 genes in head and neck cancer: Potential utility as biomarkers for prognosis

scientific article published on 29 September 2016

Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA.

scientific article published on May 2001

Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma

scientific article

Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo

scientific article

TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer

scientific article published on 31 October 2013

Thr199 phosphorylation targets nucleophosmin to nuclear speckles and represses pre-mRNA processing

scientific journal article

Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2

scientific journal article

WDR62 overexpression is associated with a poor prognosis in patients with lung adenocarcinoma

scientific article published on 9 March 2017

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