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List of works by Adelino F Leite-Moreira

2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the Eur

scientific article published on 29 August 2015

A Critical Analysis of the Available In Vitro and Ex Vivo Methods to Study Retinal Angiogenesis.

scientific article published on 7 August 2017

A Western-type diet attenuates pulmonary hypertension with heart failure and cardiac cachexia in rats.

scientific article published on 21 September 2011

A fractionation approach applying chelating magnetic nanoparticles to characterize pericardial fluid's proteome

scientific article published on 23 September 2017

Acute changes of biventricular gene expression in volume and right ventricular pressure overload

scientific article published on 23 November 2005

Acute modulation of myocardial function by angiotensin 1-7.

scientific article

Additive value of magnetic resonance coronary angiography in a comprehensive cardiac magnetic resonance stress-rest protocol for detection of functionally significant coronary artery disease: a pilot study.

scientific article published on 5 July 2013

Adipokines and their receptors: potential new targets in cardiovascular diseases.

scientific article

Adiponectin levels are elevated in patients with pulmonary arterial hypertension.

scientific article published in October 2013

Afterload induced changes in myocardial relaxation A mechanism for diastolic dysfunction

scientific article published on 01 August 1999

Afterload-induced diastolic dysfunction contributes to high filling pressures in experimental heart failure with preserved ejection fraction.

scientific article published on 25 September 2015

Agreement between echocardiographic techniques in assessment of the left ventricular myocardial performance index in rabbits

scientific article

Analyses of aqueous humour ghrelin levels of eyes with and without glaucoma

scientific article published on 01 January 2009

Analysis of heart rate variability in a rat model of induced pulmonary hypertension

scientific article published on 23 May 2010

Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.

scientific article published on March 2006

Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart.

scientific article

Angiotensin-(1-7) modulates angiotensin II-induced vasoconstriction in human mammary artery

scientific article published on 01 December 2014

Antenatal vitamin A administration attenuates lung hypoplasia by interfering with early instead of late determinants of lung underdevelopment in congenital diaphragmatic hernia

scientific article published in April 2005

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

scientific article

Association between plasma leptin and adiponectin levels and diastolic function in the general population.

scientific article published on 18 March 2015

Atherosclerosis: Recent trials, new targets and future directions

scientific article published on 08 May 2015

Attenuation of the cardiovascular and metabolic complications of obesity in CD14 knockout mice

scientific article published on 12 August 2008

Attenuation of toll-like receptor 2-mediated innate immune response in patients with alcoholic chronic liver disease

scientific article published on 13 May 2010

Beat-to-beat modulation of right and left ventricular positive dP/dt by afterload

scientific article published on 01 August 2003

Blunted renal dopaminergic system in a mouse model of diet-induced obesity

article

CAD detection in patients with intermediate-high pre-test probability: low-dose CT delayed enhancement detects ischemic myocardial scar with moderate accuracy but does not improve performance of a stress-rest CT perfusion protocol

scientific article

CT myocardial perfusion and coronary CT angiography: Influence of coronary calcium on a stress-rest protocol.

scientific article published on 30 January 2016

Cardiac dysfunction in HgCl2-induced nephrotic syndrome

scientific article published in March 2010

Cardiac magnetic resonance myocardial perfusion imaging for detection of functionally significant obstructive coronary artery disease: a prospective study

scientific article published on 24 October 2012

Cardiac remodeling and dysfunction in nephrotic syndrome

scientific article published on 25 April 2007

Cardiac venous arterialization in acute myocardial infarction: how great is the benefit?

scientific article published on 30 November 2012

Cardiac, skeletal, and smooth muscle regulation by ghrelin.

scientific article published on January 2008

Cardioprotective effects of early and late aerobic exercise training in experimental pulmonary arterial hypertension.

scientific article published on 13 October 2015

Cardiotoxicity associated with cancer therapy: pathophysiology and prevention strategies

scientific article published on 24 April 2013

Cardiovascular effects of the angiotensin type 2 receptor.

scientific article published on 31 July 2014

Cardiovascular endothelins: essential regulators of cardiovascular homeostasis.

scientific article

Central nervous system circuits modified in heart failure: pathophysiology and therapeutic implications.

scientific article

Chronic exercise induces pathological left ventricular hypertrophy in adrenaline-deficient mice

scientific article

Comparison of different methods of heart rate entropy analysis during acute anoxia superimposed on a chronic rat model of pulmonary hypertension ⬇️

scientific article published on July 18, 2012

Concomitant unipolar radiofrequency ablation of nonparoxysmal atrial fibrillation in rheumatic and degenerative valve disease

scientific article published on 19 October 2014

Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology

scientific article published on March 2016

Correlation between plasma levels of apelin and myocardial hypertrophy in rats and humans: possible target for treatment?

scientific article published in March 2010

Current pathophysiological concepts and management of pulmonary hypertension.

scientific article published on March 2012

Cystic adenomatoid malformations are induced by localized FGF10 overexpression in fetal rat lung.

scientific article published on 17 April 2008

Decreased Toll-interacting protein and peroxisome proliferator-activated receptor γ are associated with increased expression of Toll-like receptors in colon carcinogenesis.

scientific article published on 7 January 2012

Determinants of clinical improvement after surgical replacement or transcatheter aortic valve implantation for isolated aortic stenosis

scientific article

Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.

scientific article

Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment.

scientific article published on May 2012

Diastolic dysfunction in the diabetic continuum: association with insulin resistance, metabolic syndrome and type 2 diabetes.

scientific article

Diastolic tolerance to systolic pressures closely reflects systolic performance in patients with coronary heart disease

scientific article published on 05 February 2012

Direct comparison of cardiac magnetic resonance and multidetector computed tomography stress-rest perfusion imaging for detection of coronary artery disease.

scientific article

Direct downregulation of Toll-like receptors by anti-IL-2 alpha chain-receptor antibody in cadaver kidney transplant recipients

scientific article published on 01 September 2009

Direct, inflammation-mediated and blood-pressure-mediated effects of total and abdominal adiposity on diastolic function: EPIPorto study

scientific article published on May 2015

Distinct load dependence of relaxation rate and diastolic function in Oryctolagus cuniculus and Ratus norvegicus.

scientific article

Distinct mechanisms for diastolic dysfunction in diabetes mellitus and chronic pressure-overload

scientific article published on 01 May 2011

Dose-Response Head-to-Head Comparison of Inodilators Dobutamine, Milrinone, and Levosimendan in Chronic Experimental Pulmonary Hypertension.

scientific article published in March 2017

Dual antiplatelet therapy after coronary artery bypass grafting: A safe option after all? Comment on a published meta-analysis

scientific article published on 24 March 2020

ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models

scientific article published on 23 February 2014

Early results of carotid endarterectomy versus carotid stenting: Outcomes from a Mediterranean country

scientific article published on 2 April 2019

Echocardiographic evaluation including tissue Doppler imaging in New Zealand white rabbits sedated with ketamine and midazolam.

scientific article published on 28 April 2008

Echocardiography and invasive hemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study.

scientific article published on 10 April 2015

Effect of ivabradine on heart failure with preserved ejection fraction

scientific article published on 21 November 2013

Effects of adrenomedullin on systolic and diastolic myocardial function

scientific article published on 24 December 2008

Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function

scientific article published on 10 September 2009

EndoProteoFASP as a Tool to Unveil the Peptidome-Protease Profile: Application to Salivary Diagnostics

scientific article published in January 2018

Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension.

scientific article

Endothelin ETA receptors and endothelium partially mediate the positive inotropic and lusitropic effects of angiotensin II

scientific article published on 15 June 2006

Epicardial adipose tissue is an independent predictor of coronary atherosclerotic burden

scientific article published on 20 January 2011

Establishment of heart teams in Portugal

scientific article published on 24 January 2014

Exercise Training in Pulmonary Hypertension and Right Heart Failure: Insights from Pre-clinical Studies

scientific article published in January 2017

Expert position paper on the management of antiplatelet therapy in patients undergoing coronary artery bypass graft surgery

scientific article

Fetal heart development in the nitrofen-induced CDH rat model: the role of mechanical and nonmechanical factors.

scientific article published in October 2003

Functional polymorphisms of Toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans

scientific article published on 19 September 2012

Gender differences in the association of epicardial adipose tissue and coronary artery calcification: EPICHEART study: EAT and coronary calcification by gender

scientific article published on 28 September 2017

Ghrelin and ghrelin receptor inhibitors: agents in the treatment of obesity

scientific article published on 01 September 2008

Ghrelin as a novel locally produced relaxing peptide of the iris sphincter and dilator muscles

scientific article published on 10 August 2006

Ghrelin expression in human and rat fetal lungs and the effect of ghrelin administration in nitrofen-induced congenital diaphragmatic hernia

scientific article

Ghrelin, des-acyl ghrelin and obestatin: three pieces of the same puzzle

scientific article

Guía ESC 2015 sobre el tratamiento de la endocarditis infecciosa

HIV patients have impaired diastolic function that is not aggravated by anti-retroviral treatment.

scientific article published on February 2015

HMGB1 down-regulation mediates terameprocol vascular anti-proliferative effect in experimental pulmonary hypertension.

scientific article

Haemodynamic and neuroendocrine effects of tezosentan in chronic experimental pulmonary hypertension

scientific article published on 14 February 2012

Heart failure with preserved ejection fraction: fighting misconceptions for a new approach.

scientific article published on June 2011

Heart failure: statins for all?

scientific article published on 10 April 2006

Heart-related indices in experimental diaphragmatic hernia

scientific article published on 01 October 2000

Helicobacter pylori induces increased expression of Toll-like receptors and decreased Toll-interacting protein in gastric mucosa that persists throughout gastric carcinogenesis

scientific article published on 3 September 2012

How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology

scientific article published on 11 April 2007

How to use and integrate bioinformatics tools to compare proteomic data from distinct conditions? A tutorial using the pathological similarities between Aortic Valve Stenosis and Coronary Artery Disease as a case-study

scientific article

Hypertension and angiogenesis in the aging kidney: a review

scientific article published on 21 December 2010

Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.

scientific article published on 29 January 2009

Identification of the ghrelin-GHSR 1 system and its influence in the modulation of induced ocular hypertension in rabbit and rat eyes

scientific article published on 26 April 2014

Immunomodulatory role of thymulin in lung diseases.

scientific article published on February 2010

Improvement in left intraventricular pressure gradients after aortic valve replacement in aortic stenosis patients

scientific article published on 14 February 2017

Increased hepatic expression of TLR2 and TLR4 in the hepatic inflammation-fibrosis-carcinoma sequence

scientific article published on 13 February 2012

Increased nitrosative/oxidative stress lowers myocardial protein kinase G activity in heart failure with preserved ejection fraction.

scientific article published on 29 August 2013

Incremental value of adenosine stress cardiac magnetic resonance in coronary artery disease detection.

scientific article published on 12 August 2013

Incremental value of an integrated adenosine stress-rest MDCT perfusion protocol for detection of obstructive coronary artery disease.

scientific article

Influence of epicardial and visceral fat on left ventricular diastolic and systolic functions in patients after myocardial infarction.

scientific article

Inotropic and lusitropic effects of ghrelin and their modulation by the endocardial endothelium, NO, prostaglandins, GHS-R1a and KCa channels.

scientific article published on 18 January 2006

Inotropic effects of ETB receptor stimulation and their modulation by endocardial endothelium, NO, and prostaglandins.

scientific article published on 6 May 2004

Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide

scientific article published on 06 January 2012

Intermittent cardiac overload results in adaptive hypertrophy and provides protection against left ventricular acute pressure overload insult.

scientific article published on 23 June 2015

Intraventricular pressure gradients throughout the cardiac cycle: effects of ischaemia and modulation by afterload.

scientific article published on 22 June 2012

Is new grade Ia of diastolic dysfunction relevant at the population level?

scientific article published on 01 February 2015

Lack of Benefit of Ischemic Postconditioning After Routine Thrombus Aspiration During Reperfusion

scientific article published on 27 March 2015

Left intraventricular diastolic and systolic pressure gradients.

scientific article

Left ventricular diastolic dysfunction and E/E' ratio as the strongest echocardiographic predictors of reduced exercise capacity after acute myocardial infarction

scientific article published on 23 February 2015

Left ventricular hypertrophy in isolated aortic stenosis: primetime for the ventricle.

scientific article published on October 2012

Levosimendan: The current situation and new prospects

scientific article

Linear and nonlinear heart-rate analysis in a rat model of acute anoxia

scientific article published on 10 September 2008

Load dependence of left ventricular contraction and relaxation.¶Effects of caffeine

article

Load independent impairment of reverse remodeling after valve replacement in hypertensive aortic stenosis patients

scientific article published on 12 November 2013

Local modulation of the natriuretic peptide system in the rat remnant kidney

scientific article published on 14 January 2009

Low myocardial protein kinase G activity in heart failure with preserved ejection fraction

scientific article published on 17 July 2012

M-mode and Doppler echocardiographic reference values for male New Zealand white rabbits

scientific article published on 01 October 2006

METformin in DIastolic Dysfunction of MEtabolic syndrome (MET-DIME) trial: rationale and study design : MET-DIME trial.

scientific article published in April 2014

Malassezia colonisation on a reconstructed human epidermis: Imaging studies

scientific article published on 21 October 2019

Manual thrombectomy efficiency in relationship to the area at risk in patients with myocardial infarction with TIMI 0-1 coronary flow: Insights from an all comers registry

scientific article published on 13 February 2017

Meconium dependence of bowel damage in gastroschisis.

scientific article published in January 2002

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research

scientific article published on 14 December 2013

Metabolic endotoxemia: a molecular link between obesity and cardiovascular risk

scientific article

Methodological approaches and insights on protein aggregation in biological systems

scientific article published on 28 November 2016

Moderate exercise training provides left ventricular tolerance to acute pressure overload

article

Modulation of the positive inotropic effect of pyruvate by energetic substrate availability.

scientific article

Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction

scientific article published on 7 December 2015

Myocardial Titin Hypophosphorylation Importantly Contributes to Heart Failure With Preserved Ejection Fraction in a Rat Metabolic Risk Model

article

Myocardial and anti-inflammatory effects of chronic bosentan therapy in monocrotaline-induced pulmonary hypertension

scientific article published on 26 April 2014

Myocardial dysfunction and neurohumoral activation without remodeling in left ventricle of monocrotaline-induced pulmonary hypertensive rats

scientific article published on 5 May 2006

Myocardial remote ischemic preconditioning: from pathophysiology to clinical application.

scientific article published on 11 October 2013

Myocardium expression of connexin 43, SERCA2a, and myosin heavy chain isoforms are preserved in nitrofen-induced congenital diaphragmatic hernia rat model

article

Negative inotropic effect of selective AT2 receptor stimulation and its modulation by the endocardial endothelium

scientific article published on 2 October 2007

Neuregulin-1 attenuates right ventricular diastolic stiffness in experimental pulmonary hypertension

scientific article published on 02 December 2018

Neuregulin-1 improves right ventricular function and attenuates experimental pulmonary arterial hypertension

scientific article published on 26 October 2015

New pathways of the renin-angiotensin system: the role of ACE2 in cardiovascular pathophysiology and therapy.

scientific article published on May 2010

Noninvasive anatomical and functional assessment of coronary artery disease

scientific article published in April 2015

Nonlinear biphasic relationship between the time constant tau and load

scientific article published on 01 March 2000

Novel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease

scientific article

Pathophysiology of infantile pulmonary arterial hypertension induced by monocrotaline

scientific article published on 22 January 2015

Pericardial fluid: an underrated molecular library of heart conditions and a potential vehicle for cardiac therapy

scientific article published on 18 January 2019

Physiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscle

scientific article

Physiological, pathological and potential therapeutic roles of adipokines.

scientific article published on 25 April 2012

Physiological, pathological and potential therapeutic roles of ghrelin.

scientific article published on March 2007

Portuguese Society of Cardiothoracic and Vascular Surgery/Portuguese Society of Cardiology recommendations for waiting times for cardiac surgery

scientific article published on 16 October 2015

Predictors of circulating endothelial progenitor cell levels in patients without known coronary artery disease referred for multidetector computed tomography coronary angiography.

scientific article published in October 2011

Preinfarction angina

scientific article published on 01 January 2015

Pressure relaxation of the left ventricle and filling pressures

scientific article published on 01 October 2000

Prospective randomised comparison of Marsh and Schnider pharmacokinetic models for propofol during induction of anaesthesia in elective cardiac surgery

scientific article published in October 2012

Randomized controlled trial of remote ischaemic conditioning in ST-elevation myocardial infarction as adjuvant to primary angioplasty (RIC-STEMI)

scientific article published on 07 March 2018

Rationale, design and methodology for Intraventricular Pressure Gradients Study: a novel approach for ventricular filling assessment in normal and falling hearts ⬇️

scientific article

Recommendations on pre-hospital & early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Em

scientific article published on 21 May 2015

Relevance of residual left ventricular hypertrophy after surgery for isolated aortic stenosis.

scientific article published on 18 July 2015

Remote ischemic conditioning in ST-elevation myocardial infarction as adjuvant to primary angioplasty (RIC-STEMI): study protocol for a randomized controlled trial

scientific article

Remote myocardium gene expression after 30 and 120 min of ischaemia in the rat.

scientific article published on 11 January 2006

Reply to Tannous et al

scientific article published on 09 April 2014

Reverse myocardial effects of intermedin in pressure-overloaded hearts: role of endothelial nitric oxide synthase activity

scientific article published on 19 November 2012

Revisiting the slow force response: the role of the PKG signaling pathway in the normal and the ischemic heart.

scientific article published on 18 September 2014

Risk Factors for Recoarctation and Mortality in Infants Submitted to Aortic Coarctation Repair: A Systematic Review

scientific article published on 27 February 2020

Rodent models of heart failure: an updated review.

scientific article published on March 2013

Role of toll-like receptor impairment in cirrhosis infection risk: are we making progress?

scientific article published on 02 September 2010

Signaling pathways underlying skeletal muscle wasting in experimental pulmonary arterial hypertension

scientific article published on 09 October 2015

Soluble TNF-related apoptosis induced ligand (sTRAIL) is augmented by Post-Conditioning and correlates to infarct size and left ventricle dysfunction in STEMI patients: a substudy from a randomized clinical trial

scientific article published on 26 May 2016

Spectral transfer function analysis of respiratory hemodynamic fluctuations predicts end-diastolic stiffness in preserved ejection fraction heart failure

scientific article published on 16 October 2015

Surgical treatment of atrial fibrillation: an updated review.

scientific article published on 19 January 2014

Synergistic impact of endurance training and intermittent hypobaric hypoxia on cardiac function and mitochondrial energetic and signaling

scientific article published on 15 August 2013

Targeted gene transfer to fetal rat lung interstitium by ultrasound-guided intrapulmonary injection.

scientific article published in February 2007

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

scientific article

The Effect of Exercise Training on Diastolic and Systolic Function After Acute Myocardial Infarction: A Randomized Study

scientific article

The apelinergic system: the role played in human physiology and pathology and potential therapeutic applications.

scientific article published on May 2008

The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.

scientific article published on 15 January 2018

The obestatin/ghrelin system as a novel regulatory mechanism of iris muscle contraction.

scientific article published in January 2008

The role of a structured exercise training program on cardiac structure and function after acute myocardial infarction: study protocol for a randomized controlled trial

scientific article

The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases.

scientific article published on 21 October 2010

The role of titin in the modulation of cardiac function and its pathophysiological implications.

scientific article published on 25 February 2011

Therapeutic potential of neuregulin-1 in cardiovascular disease

scientific article published on 04 February 2013

Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating interleukin-6 expression and suppressing p38 pathway

scientific article published on 29 May 2008

Thyroid hormones and modulation of diastolic function: a promising target for heart failure with preserved ejection fraction

scientific article published on 04 October 2020

Time course and mechanisms of left ventricular systolic and diastolic dysfunction in monocrotaline-induced pulmonary hypertension.

scientific article published on 14 March 2009

Titin mutations: the fall of Goliath.

scientific article published on September 2015

Toll-like receptors as therapeutic targets in gastrointestinal diseases.

scientific article published on April 2010

Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC.

scientific article published on 27 June 2011

Towards the standardization of stem cell therapy studies for ischemic heart diseases: Bridging the gap between animal models and the clinical setting

scientific article published on 14 November 2016

Understanding the molecular and cellular changes behind aortic valve stenosis.

scientific article published on October 2012

Update on pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity

scientific article published on 30 October 2018

Urocortin 2 in cardiovascular health and disease

scientific article

Urotensin II acutely increases myocardial length and distensibility: potential implications for diastolic function and ventricular remodeling

scientific article published on 14 August 2007

Ventricular-arterial coupling in heart failure with preserved ejection fraction: the devil is in the details

scientific article

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