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List of works by Paula Soares

"The other side of the coin": understanding noninvasive follicular tumor with papillary-like nuclear features in unifocal and multifocal settings

scientific article published on 08 December 2018

A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms-Granting a Positive Outcome

scientific article published on 26 May 2020

A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto's Thyroiditis Susceptibility

article

A clear cell renal cell carcinoma inhibiting the response to intravitreal antivascular endothelial growth factor therapy in wet age-related macular disease

scientific article published on September 2012

A follicular variant of papillary thyroid carcinoma in struma ovarii. Case report with unique molecular alterations.

scientific article

A founder SDHB mutation in Portuguese paraganglioma patients

article

A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney–Stratakis dyad

scientific article published on 01 June 2012

A stem cell role for thyroid solid cell nests

scientific article

A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation

scientific article published on 9 May 2007

AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines ⬇️

scientific article published on October 2, 2012

Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant

scientific article published on 01 July 2001

Absence of theBRAFand theGRIM-19Mutations in Oncocytic (Hürthle Cell) Solid Cell Nests of the Thyroid

scientific article published on 01 April 2012

Acquisition of BRAF gene mutations is not a requirement for nodal metastasis of papillary thyroid carcinoma

scientific article published on 18 March 2008

Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes

scientific article published on 01 July 2005

Age-Associated Mortality Risk in Papillary Thyroid Cancer: Does BRAF Make a Real Difference?

scientific article published on 23 March 2018

Alopecia in women submitted to childhood X-ray epilation for tinea capitis treatment

scientific article published on 08 May 2010

An assessment of the clonality of the components of canine mixed mammary tumours by mitochondrial DNA analysis

scientific article

Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas

scientific article published on 30 August 2010

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

scientific article published on 01 July 2003

BRAF mutations are associated with some histological types of papillary thyroid carcinoma

scientific article published on 01 February 2004

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations

scientific article published on February 2008

BRAFV600Emutation in papillary thyroid carcinoma: a potential target for therapy?

scientific article published on 01 September 2009

Benign and malignant thyroid lesions show instability at microsatellite loci

scientific article published on 01 February 1997

Biomarkers for Bladder Cancer Diagnosis and Surveillance: A Comprehensive Review

scientific article published on 13 January 2020

C-Cell-Derived Calcitonin-Free Neuroendocrine Carcinoma of the Thyroid

scientific article published on 04 March 2014

CDX2 Expression in Some Variants of Papillary Thyroid Carcinoma

scientific article published on 01 December 2012

CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension

scientific article published on 10 January 2018

Calcitonin receptor expression in medullary thyroid carcinoma

scientific article published on 13 September 2017

Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells

scientific article published on 8 November 2010

Clinical Validation of a Urine Test (Uromonitor-V2®) for the Surveillance of Non-Muscle-Invasive Bladder Cancer Patients

scientific article published on 24 September 2020

Clinicopathological Features as Prognostic Predictors of Poor Outcome in Papillary Thyroid Carcinoma

scientific article published on 29 October 2020

Clonal cytogenetic abnormalities and telomeric associations in a fibroxanthoma of the stomach

scientific article published on 01 November 1992

Coexistence of TERT promoter and BRAF mutations in papillary thyroid carcinoma: added value in patient prognosis?

scientific article published on 20 January 2015

Comments on: Mutations in Mitochondrial Control Region DNA in Gastric Tumours of Japanese Patients, Tamura, et al. Eur J Cancer 1999, 35, 316–319

scientific article published on 01 September 1999

Comprehensive Assessment of TERT mRNA Expression across a Large Cohort of Benign and Malignant Thyroid Tumours

scientific article published on 09 July 2020

Core I gene is overexpressed in Hürthle and non-Hürthle cell microfollicular adenomas and follicular carcinomas of the thyroid

scientific article

Corrigendum to "How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer".

scientific article published on 28 June 2016

Cribriform-Morular Variant of Papillary Thyroid Carcinoma

scientific article published on 01 January 2009

Cribriform-Morular Variant of Papillary Thyroid Carcinoma Displaying Poorly Differentiated Features

scientific article published on 24 January 2013

Cribriform-morular variant of thyroid carcinoma: a neoplasm with distinctive phenotype associated with the activation of the WNT/β-catenin pathway

scientific article published on 21 May 2018

Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation

scientific article published on 17 September 2008

Cystic tumor of the atrioventricular node of the heart appears to be the heart equivalent of the solid cell nests (ultimobranchial rests) of the thyroid

scientific article published on 01 March 2005

Cytogenetic findings in eleven gastric carcinomas

scientific article published in July 1993

Differential Expression of HMGA1 and HMGA2 in pituitary neuroendocrine tumors

scientific article published on 15 April 2019

Differentiated thyroid cancer in patients with resistance to thyroid hormone syndrome. A novel case and a review of the literature.

scientific article published on 2 September 2014

Diffuse (or multinodular) follicular variant of papillary thyroid carcinoma: a clinicopathologic and immunohistochemical analysis of ten cases of an aggressive form of differentiated thyroid carcinoma.

scientific article published on 12 December 2001

Dynamin-Related Protein 1 at the Crossroads of Cancer.

scientific article published on 21 February 2018

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

article

E-cadherin gene alterations are rare events in thyroid tumors

article

E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas

scientific article

EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide

scientific article published on January 2011

ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome

scientific article

Erratum to "Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism"

scientific article published on 18 June 2020

Erratum: Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells

scientific article published on 08 August 2016

Etiopathogenesis of oncocytomas

scientific article

Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma

scientific article published in April 2010

Extended structural variation of a pentanucleotide repeat in the GSTP1 gene: characterisation in a normal population and in thyroid and gastric tumours

article

Fetal adenomas and minimally invasive follicular carcinomas of the thyroid frequently display a triploid or near triploid DNA pattern

article

Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth

scientific article published on 07 July 2008

Follicular thyroid lesions: is there a discriminatory potential in the computerized nuclear analysis?

scientific article published on 04 July 2018

Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families

scientific article published on 01 January 2000

Frequency of TERT promoter mutations in human cancers

scientific article published on January 2013

Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis

scientific article published on 31 July 2017

GLUT1, MCT1/4 and CD147 overexpression supports the metabolic reprogramming in papillary renal cell carcinoma

scientific article published on 28 December 2016

GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells.

scientific article published on 23 July 2013

GRIM-19 function in cancer development

scientific article published on 02 June 2011

GRIM-19 in Health and Disease.

scientific article published in January 2008

Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism

scientific article published in August 2019

Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas

scientific article published on December 2011

Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment

scientific article published on 3 October 2013

Genomic and transcriptomic characterization of the mitochondrial-rich oncocytic phenotype on a thyroid carcinoma background

scientific article published on 6 April 2018

Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia.

scientific article published in October 2003

Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer.

scientific article

H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid

scientific article published on 13 March 2006

Head and neck basal cell carcinoma prevalence in individuals submitted to childhood X-ray epilation for tinea capitis treatment

scientific article

Head and neck lesions in a cohort irradiated in childhood for tinea capitis treatment

scientific article published on 01 March 2011

Hobnail Variant of Papillary Thyroid Carcinoma: Clinicopathologic and Molecular Evidence of Progression to Undifferentiated Carcinoma in 2 Cases.

scientific article published on 22 December 2016

Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.

scientific article published on 3 November 2015

How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer

scientific article published on 23 June 2011

IL6-174 G>C Polymorphism (rs1800795) Association with Late Effects of Low Dose Radiation Exposure in the Portuguese Tinea Capitis Cohort

scientific article

Identification of a paired box gene 8–peroxisome proliferator-activated receptor gamma (PAX8–PPARγ) rearrangement mosaicism in a patient with an autonomous functioning follicular thyroid carcinoma bearing an activating mutation in the TSH recept

article

Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production.

scientific article published in June 2003

Impact of EGFR genetic variants on glioma risk and patient outcome.

scientific article

In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp

scientific article

Increased lymphangiogenesis in Riedel thyroiditis (Immunoglobulin G4-related thyroid disease)

scientific article published on 11 July 2014

Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer

scientific article

Insights into melanoma: targeting the mTOR pathway for therapeutics

scientific article published on 24 May 2012

Intragenic mutations in thyroid cancer.

scientific article published on June 2008

Intratumoural lymph vessel density is related to presence of lymph node metastases and separates encapsulated from infiltrative papillary thyroid carcinoma.

scientific article

Introduction

Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone.

scientific article

Is BRAF mutation screening useful for preoperative risk stratification in papillary thyroid cancer?

scientific article published on October 2009

Is Low-Dose Radiation Exposure a Risk Factor for Atherosclerotic Disease?

scientific article published on 20 February 2018

Liposomal therapies in oncology: does one size fit all?

scientific article published on 16 August 2018

Loss of Y chromosome in gastric carcinoma

scientific article published on 01 July 1992

Loss of heterozygosity at 19p13.2 and 2q21 in tumours from familial clusters of non-medullary thyroid carcinoma

scientific article published on 07 September 2007

Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs).

scientific article published on 24 September 2014

MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism

scientific article

Melanocytic Tumour in a Black Sheep never exposed to Ultraviolet Radiation

scientific article published on 25 May 2011

Melanoma treatment in review.

scientific article published on 7 June 2018

Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma

scientific article published on 01 October 2001

Mitochondrial D-Loop instability in thyroid tumours is not a marker of malignancy

scientific article published on 01 October 2005

Mitochondrial D310 D-Loop instability and histological subtypes in radiation-induced cutaneous basal cell carcinomas.

scientific article published on 10 September 2013

Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration

scientific article

Molecular Alterations in Sporadic Primary Hyperparathyroidism ⬇️

scientific article published on September 8, 2011

Molecular Aspects of Thyroid Calcification

scientific article published on 19 October 2020

Molecular Markers Involved in Tumorigenesis of Thyroid Carcinoma: Focus on Aggressive Histotypes

scientific article published on 24 February 2017

Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors.

scientific article published on 5 September 2012

Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines

scientific article published on August 2007

Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas.

scientific article published in April 2016

Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex

scientific article published on 21 March 2002

Multicentre validation study of nucleic acids extraction from FFPE tissues.

scientific article

Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.

scientific article published on 10 March 2018

Mutation analysis of B-RAF gene in human gliomas.

scientific article published on 17 November 2004

NIS expression in thyroid tumors, relation with prognosis clinicopathological and molecular features

scientific article published in January 2018

Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells

scientific article published on 13 June 2013

OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines

scientific article published on 30 September 2018

OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration.

scientific article published on 11 December 2014

Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal

scientific article published on June 2006

Optimization of methods to assess mitochondrial DNA in archival paraffin-embedded tissues from mammary canine tumors

article by Angélica C. Bertagnolli et al published August 2008 in Jornal brasileiro de patologia e medicina laboratorial

Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR.

scientific article

Osteopontin expression is correlated with differentiation and good prognosis in medullary thyroid carcinoma

scientific article published on 25 January 2016

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

scientific article published on 07 July 2016

Other Rare Tumours and Tumour-Like Lesions

Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy.

scientific article published on June 2015

Papillary thyroid microcarcinoma: how to diagnose and manage this epidemic?

scientific article published on 07 January 2014

Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.

scientific article published on January 2012

Polymorphisms in the TNFA and IL6 genes represent risk factors for autoimmune thyroid disease

scientific article

Poorly Differentiated and Undifferentiated Thyroid Carcinomas

scientific article

Predictive Biomarkers and Patient Outcome in Platinum-Resistant (PLD-Treated) Ovarian Cancer

scientific article published on 28 July 2020

Primary squamous cell carcinoma of the thyroid diagnosed as anaplastic carcinoma: failure in fine-needle aspiration cytology?

scientific article

Prognostic Significance of RAS Mutations and P53 Expression in Cutaneous Squamous Cell Carcinomas

scientific article published on 06 July 2020

Prognostic biomarkers in thyroid cancer

scientific article published on February 2014

Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.

scientific article

Proliferative activity of human thyroid tumors evaluated by proliferating cell nuclear antigen/cyclin immunohistochemical studies

scientific article published on 01 June 1994

RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation

scientific article published on 8 August 2015

RE: TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma.

scientific article published on 9 March 2015

RET/PTC rearrangement is prevalent in follicular Hürthle cell carcinomas.

scientific article published on 17 July 2012

Rare Familial Tumours

Rare Follicular Tumours

Rare Papillary Thyroid Carcinomas

Relative Y-STR mutation rates estimated from the variance inside SNP defined lineages

article

Reliable blood cancer cells' telomere length evaluation by qPCR

scientific article published on 06 March 2020

Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas

scientific article published on 01 December 2005

SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma

scientific article

STAT3 negatively regulates thyroid tumorigenesis

scientific journal article

Scalp basal cell carcinoma: A different entity?

scientific article published on 30 January 2019

Selenium and Selenoproteins in Immune Mediated Thyroid Disorders

scientific article published on 4 October 2018

Signet Ring Cell Carcinoma of the Stomach: A Morphometric, Ultrastructural, and DNA Cytometric Study

scientific article published on 01 November 1992

Small Cell Tumours

Small papillary thyroid cancers—is BRAF of prognostic value?

scientific article published on 01 January 2011

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.

scientific article published on May 2005

Sporadic ret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

scientific article published in May 1998

Stimulated thyroglobulin at recombinant human TSH-aided ablation predicts disease-free status one year later

scientific article published on 13 September 2013

Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes

scientific article published on 7 September 2012

Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death

scientific article published in September 2011

TERT Promoter Mutation as a Potential Predictive Biomarker in BCG-Treated Bladder Cancer Patients

scientific article published on 31 January 2020

TERT biology and function in cancer: beyond immortalisation

scientific article published on 5 January 2017

TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas

scientific article

TERT promoter mutations are associated with poor prognosis in cutaneous squamous cell carcinoma

scientific article published on 28 August 2018

TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes

scientific article published on 14 July 2016

TERT promoter mutations in skin cancer: the effects of sun exposure and X-irradiation.

scientific article published on April 2014

TERT promoter mutations in soft tissue sarcomas

scientific article published on 28 February 2016

TERT promoter mutations: a genetic signature of benign and malignant thyroid tumours occurring in the context of tinea capitis irradiation

scientific article

TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease

scientific article published on 6 March 2017

TERTp mutation is associated with a shorter progression free survival in patients with aggressive histology subtypes of follicular-cell derived thyroid carcinoma

scientific article published on 15 June 2018

TGF-beta/Smad pathway and BRAF mutation play different roles in circumscribed and infiltrative papillary thyroid carcinoma

scientific article published on 20 April 2012

Tackling Thyroid Cancer in Europe-The Challenges and Opportunities

scientific article published on 25 August 2022

Telomerase Activation in Hematological Malignancies

scientific article

Telomerase and N-Cadherin Differential Importance in Adrenocortical Cancers and Adenomas

scientific article published on 25 November 2016

Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests

scientific article published in July 2004

Telomerase promoter mutations in cancer: an emerging molecular biomarker?

scientific article

Telomere Maintenance Mechanisms in Cancer.

scientific article

The Genetics of Papillary Microcarcinomas of the Thyroid: Diagnostic and Prognostic Implications

scientific article published on June 2017

The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype

scientific article

The biology and the genetics of Hurthle cell tumors of the thyroid.

scientific article published on 18 July 2012

The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats

scientific article published on 11 June 2018

The genetics of cutaneous squamous cell carcinogenesis

scientific article published on 01 October 2018

The mTOR Signalling Pathway in Human Cancer ⬇️

scientific article published on February 10, 2012

The p75 neurotrophin receptor is widely expressed in conventional papillary thyroid carcinoma

scientific article published on 01 May 2006

The preeminence of growth pattern and invasiveness and the limited influence of BRAF and RAS mutations in the occurrence of papillary thyroid carcinoma lymph node metastases

scientific article published on 28 July 2011

The role of ablative treatment in differentiated thyroid cancer management

scientific article published on 10 February 2017

Therapeutic Options

Thyroid and Parathyroid Glands

Thyroid and parathyroid tumours in patients submitted to X-ray scalp epilation during the tinea capitis eradication campaign in the North of Portugal (1950-1963).

scientific article published on 22 August 2014

Thyroid hormone as a regulator of tumor induced angiogenesis

scientific article published on 22 December 2010

Tributyltin and Zebrafish: Swimming in Dangerous Water.

scientific article published on 10 April 2018

Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?

scientific article published on 6 January 2011

Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients’ age but not with tumour aggressiveness

scientific article published on 19 May 2005

Unraveling molecular targets of bisphenol A and S in the thyroid gland

scientific article published on 13 July 2018

Vascular invasion in thyroid and gastric carcinomas.

scientific article

mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression.

scientific article published on 13 May 2018

mTOR activation in medullary thyroid carcinoma with RAS mutation.

scientific article published on 27 August 2014

mTOR pathway activation in cutaneous melanoma is associated with poorer prognosis characteristics.

scientific article

mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.

scientific article published on May 2012

p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin

scientific article published on January 2003

pmTOR is a marker of aggressiveness in papillary thyroid carcinomas

scientific article published on 26 August 2016

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