List of works - Pierre Verhaeghe

2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of

scientific article published on 26 July 2021

4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.

scientific article

8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases

scientific article published on 01 August 2018

A new synthetic route to original sulfonamide derivatives in 2-trichloromethylquinazoline series: a structure-activity relationship study of antiplasmodial activity.

scientific article

A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania

scientific article

Access to original vinylic chlorides in the quinazoline series via a monoelectronic transfer reaction approach.

scientific article published on 13 April 2010

Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4-]pyrazines

scientific article published on 16 October 2018

Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series.

scientific article

Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions

scholarly article by Julien Pedron et al published 17 September 2018 in ChemMedChem

Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay

scientific article published on 15 June 2011

Discovery of a new antileishmanial hit in 8-nitroquinoline series

scientific article published on 02 May 2012

Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold.

scientific article published on 10 September 2016

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

scientific article published on 10 March 2015

Ionic Polypeptide Polymers with Unusual β-Sheet Stability

Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series

scientific article

Looking for new antiplasmodial quinazolines: DMAP-catalyzed synthesis of 4-benzyloxy- and 4-aryloxy-2-trichloromethylquinazolines and their in vitro evaluation toward Plasmodium falciparum

scientific article published on 28 April 2016

Nitrated isomers of 2-(trichloromethyl)quinoline

scientific article

Nongenotoxic 3-Nitroimidazo[1,2-]pyridines Are NTR1 Substrates That Display Potent Antileishmanial Activity

scientific article published on 19 December 2018

Novel 8-nitroquinolin-2(1 H )-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study

scientific article published on 05 June 2018

Original quinazoline derivatives displaying antiplasmodial properties.

scientific article

Pharmacomodulation of a sulfamide 5-HT6 receptor ligand

scientific article published in December 2004

Preventing the contamination of hospital personnel by cytotoxic agents: evaluation and training of the para-professional healthcare workers in oncology units

scientific article published on 7 October 2014

Quinoline derivatives: potential antiparasitic and antiviral agents

scientific article published on 13 October 2007

Regioselective Suzuki-Miyaura reaction: application to the microwave-promoted synthesis of 4,7-diarylquinazolines.

scientific article published on 27 April 2010

Safety review: squalene and thimerosal in vaccines

scientific article

Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-Trichloromethyl Quinazolines

scientific article published on 27 August 2020

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines

scientific article published on 17 October 2007

Synthesis and evaluation of monoamidoxime derivatives: toward new antileishmanial compounds.

scientific article published on 15 April 2011

Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines.

scientific article

Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents.

scientific article published on 10 June 2014

Tandem synthesis and in vitro antiplasmodial evaluation of new naphtho[2,1-d]thiazole derivatives

scientific article

Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series

scientific article published on 23 June 2011

Targeting the human parasite Leishmania donovani: discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series

scientific article

List of works by Pierre Verhaeghe

2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of

4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.

8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases

A new synthetic route to original sulfonamide derivatives in 2-trichloromethylquinazoline series: a structure-activity relationship study of antiplasmodial activity.

A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania

Access to original vinylic chlorides in the quinazoline series via a monoelectronic transfer reaction approach.

Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4-]pyrazines

Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series.

Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions

Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay

Discovery of a new antileishmanial hit in 8-nitroquinoline series

Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold.

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

Ionic Polypeptide Polymers with Unusual β-Sheet Stability

Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series

Looking for new antiplasmodial quinazolines: DMAP-catalyzed synthesis of 4-benzyloxy- and 4-aryloxy-2-trichloromethylquinazolines and their in vitro evaluation toward Plasmodium falciparum

Nitrated isomers of 2-(trichloromethyl)quinoline

Nongenotoxic 3-Nitroimidazo[1,2-]pyridines Are NTR1 Substrates That Display Potent Antileishmanial Activity

Novel 8-nitroquinolin-2(1 H )-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study

Original quinazoline derivatives displaying antiplasmodial properties.

Pharmacomodulation of a sulfamide 5-HT6 receptor ligand

Preventing the contamination of hospital personnel by cytotoxic agents: evaluation and training of the para-professional healthcare workers in oncology units

Quinoline derivatives: potential antiparasitic and antiviral agents

Regioselective Suzuki-Miyaura reaction: application to the microwave-promoted synthesis of 4,7-diarylquinazolines.

Safety review: squalene and thimerosal in vaccines

Synthesis and Antiplasmodial Evaluation of 4-Carboxamido- and 4-Alkoxy-2-Trichloromethyl Quinazolines

Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines

Synthesis and evaluation of monoamidoxime derivatives: toward new antileishmanial compounds.

Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines.

Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents.

Tandem synthesis and in vitro antiplasmodial evaluation of new naphtho[2,1-d]thiazole derivatives

Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series

Targeting the human parasite Leishmania donovani: discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series