List of works - Shile Huang

A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesis

scientific article

A deut of mTORC1/2 for cell adhesion

scientific article published on January 2015

A long noncoding RNA critically regulates Bcr-Abl-mediated cellular transformation by acting as a competitive endogenous RNA.

scientific article published on 19 May 2014

A new clue to explain resistance to mTOR inhibitors ⬇️

scientific article published on March 1, 2012

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

scientific article

An insight of rapamycin against cadmium's neurotoxicity.

scientific article published on 28 January 2017

Artesunate enhances the immune response of rabies vaccine as an adjuvant

scientific article published on 30 September 2019

Avermectin induces P-glycoprotein expression in S2 cells via the calcium/calmodulin/NF-κB pathway

scientific article published on 22 March 2013

BAFF activates Erk1/2 promoting cell proliferation and survival by Ca2+-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells.

scientific article

BAFF inhibits autophagy promoting cell proliferation and survival by activating Ca2+-CaMKII-dependent Akt/mTOR signaling pathway in normal and neoplastic B-lymphoid cells

scientific article published on 20 September 2018

Biological activities of fusarochromanone: a potent anti-cancer agent

scientific article

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.

scientific article published on March 2015

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

scientific journal article

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

scientific journal article

Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells

scientific article published on 05 February 2020

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

scientific journal article

Cadmium results in accumulation of autophagosomes-dependent apoptosis through activating Akt-impaired autophagic flux in neuronal cells

scientific article published on 19 December 2018

Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

scientific article

Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway

scientific article published on 27 November 2016

Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway

scientific article

Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway

scientific article published on 20 October 2016

Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.

scientific article

Ciclopirox activates ATR-Chk1 signaling pathway leading to Cdc25A protein degradation.

scientific article

Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway

scientific article

Ciclopirox inhibits cancer cell proliferation by suppression of Cdc25A.

scientific article

Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.

scientific article published on 7 July 2016

Concerted suppression of STAT3 and GSK3β is involved in growth inhibition of non-small cell lung cancer by Xanthatin

scientific article

Correction to: Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells

scientific article published on 21 March 2019

Correction: Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

scientific article published on 14 January 2016

Corrigendum to "Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells" [Toxicol. Lett. 284 (2018) 96-102]

scientific article published on 10 September 2018

Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis.

scientific article published on 03 February 2016

Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells

scientific article

Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation ⬇️

scientific article

Cryptotanshinone inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3/ERK and small GTPase pathways

scientific article published on 31 August 2011

Curcumin disrupts the Mammalian target of rapamycin-raptor complex.

scientific article

Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion

scientific article

Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.

scientific article published on 31 January 2012

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

scientific article

Current development of the second generation of mTOR inhibitors as anticancer agents

scientific article

Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells

scientific article published on 08 August 2013

Downregulation of Integrins in Cancer Cells and Anti-Platelet Properties Are Involved in Holothurian Glycosaminoglycan-Mediated Disruption of the Interaction of Cancer Cells and Platelets in Hematogenous Metastasis

scientific article published on 22 October 2015

Editorial [Hot Topic: Novel Protein & Peptide Science (Guest Editor: Shile Huang)]

scientific article published on 01 February 2011

Erratum

scholarly article published in Autophagy

Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

scientific article published on 15 September 2019

Fusarochromanone induces G1 cell cycle arrest and apoptosis in COS7 and HEK293 cells

scientific article

Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5.

scientific article published on 17 October 2015

Ganoderma lucidum Polysaccharides as An Anti-cancer Agent

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hitting the golden TORget: curcumin's effects on mTOR signaling

scientific article published on September 2013

Host Immune Response to Influenza A Virus Infection.

scientific article published on 5 March 2018

Human Albumin Prevents 6-Hydroxydopamine-Induced Loss of Tyrosine Hydroxylase in In Vitro and In Vivo ⬇️

scientific article published on July 17, 2012

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

scientific article

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

scientific journal article

IL-2, IL-4, IFN-γ or TNF-α enhances BAFF-stimulated cell viability and survival by activating Erk1/2 and S6K1 pathways in neoplastic B-lymphoid cells

scientific article published on 25 May 2016

Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling

scientific article

Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.

scientific article

Inhibition of PI3K/Akt/mTOR signaling by natural products

scientific article published on September 2013

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity

scientific article published on 24 June 2004

Inhibition of vascular endothelial growth factor-mediated angiogenesis involved in reproductive toxicity induced by sesquiterpenoids of Curcuma zedoaria in rats.

scientific article published on 11 February 2013

Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

scientific article

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

scientific article published on January 2003

Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis

Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways

scientific article published on 15 June 2020

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

scientific article published on 16 November 2007

Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells

scientific article published on 17 July 2019

Maduramicin induces apoptosis and necrosis, and blocks autophagic flux in myocardial H9c2 cells.

scientific article

Maduramicin induces apoptosis through ROS-PP5-JNK pathway in skeletal myoblast cells and muscle tissue

scientific article published on 20 June 2019

Maduramicin induces cardiac muscle cell death by the ROS-dependent PTEN/Akt-Erk1/2 signaling pathway

scientific article published on 03 December 2018

Maduramicin inhibits proliferation and induces apoptosis in myoblast cells

scientific article published on 22 December 2014

Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells.

scientific article

Mechanisms of resistance to rapamycins

scientific article (publication date: December 2001)

Molecular evidence of cryptotanshinone for treatment and prevention of human cancer

scientific article published on September 2013

N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

scientific article

Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo

scientific article published on 26 February 2007

Nitric oxide-mediated cGMP synthesis in Helix neural ganglia.

scientific article published on January 1998

Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway

scientific article published on 08 April 2019

PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation

scientific article published on January 2014

PP2A Level in Colorectal Cancer Cells Predicts the Response of p38 Targeted Therapy

scientific article published on 15 December 2015

Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.

scientific article published on 21 January 2016

Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells

scientific article

Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca2+-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells

scientific article published on 07 February 2020

Rapamycin inhibits BAFF-stimulated cell proliferation and survival by suppressing mTOR-mediated PP2A-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells

scientific article

Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.

scientific article

Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins

scientific article

Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway

scientific article

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways

scientific article published on 22 May 2006

Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

scientific article

Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression.

scientific article published in March 2012

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.

scientific article published on February 2015

Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways

scientific article

Rapamycins: mechanism of action and cellular resistance

scientific article

ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells

scientific article published on 28 June 2019

Repositioning the Old Fungicide Ciclopirox for New Medical Uses.

scientific article published on 30 May 2016

Resistance to rapamycin: a novel anticancer drug

scientific article

Resveratrol inhibits Erk1/2-mediated adhesion of cancer cells via activating PP2A-PTEN signaling network

scientific article published on 01 August 2018

Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5.

scientific article published on 4 July 2015

Rhabdovirus Infection Is Dependent on Serine/Threonine Kinase AP2-Associated Kinase 1

scientific article published on 30 August 2020

Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy

scientific article published on 31 July 2019

Role of mTOR signaling in tumor cell motility, invasion and metastasis

scientific article published on February 2011

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis

scientific article

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

scientific article published on 5 September 2017

Suppression of interferon lambda signaling by SOCS-1 results in their excessive production during influenza virus infection

scientific article

Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)

scientific article (publication date: June 2003)

Targeting mTOR signaling for cancer therapy

scientific article

The antitumor activity of the fungicide ciclopirox

scientific article published on November 2010

The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression

scientific article published on 15 January 2019

The complexes of mammalian target of rapamycin.

scientific article

The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway

scientific article published on 10 January 2011

The role of Cdc25A in the regulation of cell proliferation and apoptosis

scientific journal article

The targets of curcumin.

scientific article published on March 2011

Tracing brain genotoxic stress in Parkinson's disease with a novel single-cell genetic sensor

scientific article published on 15 April 2022

Triclabendazole protects yeast and mammalian cells from oxidative stress: Identification of a potential neuroprotective compound ⬇️

scientific article published on September 16, 2011

Understanding of leukemic stem cells and their clinical implications.

scientific article published on 30 January 2017

Updates of mTOR inhibitors

scientific article

eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants.

scientific article published on 03 February 2016

eIF4B phosphorylation by pim kinases plays a critical role in cellular transformation by Abl oncogenes

scientific article published on 7 June 2013

mTOR Signaling in Metabolism and Cancer

scientific article published on 13 October 2020

mTOR as a target for cancer therapy.

scientific article published on January 2004

p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.

scientific article published in April 2001

α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2

scientific article

List of works by Shile Huang

A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesis

A deut of mTORC1/2 for cell adhesion

A long noncoding RNA critically regulates Bcr-Abl-mediated cellular transformation by acting as a competitive endogenous RNA.

A new clue to explain resistance to mTOR inhibitors ⬇️

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

An insight of rapamycin against cadmium's neurotoxicity.

Artesunate enhances the immune response of rabies vaccine as an adjuvant

Avermectin induces P-glycoprotein expression in S2 cells via the calcium/calmodulin/NF-κB pathway

BAFF activates Erk1/2 promoting cell proliferation and survival by Ca2+-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells.

BAFF inhibits autophagy promoting cell proliferation and survival by activating Ca2+-CaMKII-dependent Akt/mTOR signaling pathway in normal and neoplastic B-lymphoid cells

Biological activities of fusarochromanone: a potent anti-cancer agent

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

Cadmium results in accumulation of autophagosomes-dependent apoptosis through activating Akt-impaired autophagic flux in neuronal cells

Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway

Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway

Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway

Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.

Ciclopirox activates ATR-Chk1 signaling pathway leading to Cdc25A protein degradation.

Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway

Ciclopirox inhibits cancer cell proliferation by suppression of Cdc25A.

Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.

Concerted suppression of STAT3 and GSK3β is involved in growth inhibition of non-small cell lung cancer by Xanthatin

Correction to: Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells

Correction: Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

Corrigendum to "Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells" [Toxicol. Lett. 284 (2018) 96-102]

Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis.

Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells

Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation ⬇️

Cryptotanshinone inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3/ERK and small GTPase pathways

Curcumin disrupts the Mammalian target of rapamycin-raptor complex.

Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion

Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

Current development of the second generation of mTOR inhibitors as anticancer agents

Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells

Downregulation of Integrins in Cancer Cells and Anti-Platelet Properties Are Involved in Holothurian Glycosaminoglycan-Mediated Disruption of the Interaction of Cancer Cells and Platelets in Hematogenous Metastasis

Editorial [Hot Topic: Novel Protein & Peptide Science (Guest Editor: Shile Huang)]

Erratum

Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

Fusarochromanone induces G1 cell cycle arrest and apoptosis in COS7 and HEK293 cells

Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5.

Ganoderma lucidum Polysaccharides as An Anti-cancer Agent

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Hitting the golden TORget: curcumin's effects on mTOR signaling

Host Immune Response to Influenza A Virus Infection.

Human Albumin Prevents 6-Hydroxydopamine-Induced Loss of Tyrosine Hydroxylase in In Vitro and In Vivo ⬇️

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

IL-2, IL-4, IFN-γ or TNF-α enhances BAFF-stimulated cell viability and survival by activating Erk1/2 and S6K1 pathways in neoplastic B-lymphoid cells

Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling

Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression.

Inhibition of PI3K/Akt/mTOR signaling by natural products

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity

Inhibition of vascular endothelial growth factor-mediated angiogenesis involved in reproductive toxicity induced by sesquiterpenoids of Curcuma zedoaria in rats.

Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis

Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells

Maduramicin induces apoptosis and necrosis, and blocks autophagic flux in myocardial H9c2 cells.

Maduramicin induces apoptosis through ROS-PP5-JNK pathway in skeletal myoblast cells and muscle tissue

Maduramicin induces cardiac muscle cell death by the ROS-dependent PTEN/Akt-Erk1/2 signaling pathway

Maduramicin inhibits proliferation and induces apoptosis in myoblast cells

Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells.

Mechanisms of resistance to rapamycins

Molecular evidence of cryptotanshinone for treatment and prevention of human cancer

N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo

Nitric oxide-mediated cGMP synthesis in Helix neural ganglia.

Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway

PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation

PP2A Level in Colorectal Cancer Cells Predicts the Response of p38 Targeted Therapy

Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.