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List of works by Martino Luigi di Salvo

A Bioinformatics Analysis Reveals a Group of MocR Bacterial Transcriptional Regulators Linked to a Family of Genes Coding for Membrane Proteins

scientific article published on 30 June 2016

A Comprehensive Computational Analysis of Mycobacterium Genomes Pinpoints the Genes Co-occurring with YczE, a Membrane Protein Coding Gene Under the Putative Control of a MocR, and Predicts its Function.

scientific article

Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase

scientific article

Alanine racemase from Tolypocladium inflatum: A key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity

scientific article (publication date: 2013)

Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from Escherichia coli

scientific article published on 04 September 2019

An Engineered Escherichia coli Strain with Synthetic Metabolism for In-cell Production of Translationally Active Methionine Derivatives

scientific article published on 31 July 2020

Asymmetry of the active site loop conformation between subunits of glutamate-1-semialdehyde aminomutase in solution

scientific article published on 31 July 2013

Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO).

scientific article published on 28 October 2017

Biomedical aspects of pyridoxal 5 -phosphate availability

scientific article published on January 1, 2012

Conserved water molecules in bacterial serine hydroxymethyltransferases

scientific article published on 18 May 2015

Corrigendum to "Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation" [Mol. Genet. Metab. 122/1-2 (2017) 135-142]

scientific article published on 14 March 2018

Coupling bioorthogonal chemistries with artificial metabolism: intracellular biosynthesis of azidohomoalanine and its incorporation into recombinant proteins.

scientific article published on 15 January 2014

Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation

scientific article

Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

scientific article

Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases

scientific article published on June 2006

Crystal structure of the PdxY Protein from Escherichia coli.

scientific article published on December 2004

Crystallization and preliminary X-ray crystallographic analysis of pyridoxine 5'-phosphate oxidase complexed with flavin mononucleotide

scientific article published in August 1999

Data from computational analysis of the peptide linkers in the MocR bacterial transcriptional regulators

scientific article

Deamidation of asparagine residues in a recombinant serine hydroxymethyltransferase

scientific article published in December 1999

Detection of isoAspartate residues as a posttranslational modification of proteins and peptides

scientific article

Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.

scientific article published on 13 August 2016

Distribution of B6 vitamers in Escherichia coli as determined by enzymatic assay

scientific article published in November 2001

Editorial: PLP-Dependent Enzymes: Extraordinary Versatile Catalysts and Ideal Biotechnological Tools for the Production of Unnatural Amino Acids and Related Compounds

scientific article published on 11 February 2020

Enzymatic determination of homocysteine in cell extracts.

scientific article

Expression, purification, and characterization of human cytosolic serine hydroxymethyltransferase

scientific article published in August 1995

Expression, purification, and characterization of recombinant Escherichia coli pyridoxine 5'-phosphate oxidase

scientific article

Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases

scientific article published in August 2004

Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection

scientific article published on 6 March 2013

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

scientific article

Identification and characterization of the pyridoxal 5’-phosphate allosteric site in Escherichia coli pyridoxine 5’-phosphate oxidase

scientific article published in 2021

In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed

scientific article (publication date: May 2011)

Inhibition of human pyridoxal kinase by 2-acetyl-4-((1R,2S,3R)-1,2,3,4-tetrahydroxybutyl)imidazole (THI).

scientific article

Interaction of Bacillus subtilis GabR with the gabTD promoter: role of repeated sequences and effect of GABA in transcriptional activation

scientific article published on 09 March 2020

Isolation of a Complex Formed Between HemA and HemL, Key Enzymes of Tetrapyrroles Biosynthesis

scientific article published on 26 February 2019

Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase

scientific article

Molecular Basis of Reduced Pyridoxine 5′-Phosphate Oxidase Catalytic Activity in Neonatal Epileptic Encephalopathy Disorder

scientific article

Molecular basis of E. coli L-threonine aldolase catalytic inactivation at low pH.

scientific article

Molecular characterization of pyridoxine 5'-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy

scientific article published on 12 August 2020

Molecular mechanism of PdxR – a transcriptional activator involved in the regulation of vitamin B6 biosynthesis in the probiotic bacterium Bacillus clausii

scientific article published on 26 June 2015

Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis.

scientific article published on 27 July 2015

On the catalytic mechanism and stereospecificity ofEscherichia colil-threonine aldolase

scientific article

On the mechanism of Escherichia coli pyridoxal kinase inhibition by pyridoxal and pyridoxal 5'-phosphate

scientific article published on 3 February 2015

Purification and Characterization of Recombinant Rabbit Cytosolic Serine Hydroxymethyltransferase

scientific article published on July 1, 1998

Pyridoxal 5'-phosphate enzymes as targets for therapeutic agents

scientific article published on January 2007

Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase.

scientific article

Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation.

scientific article

Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase

scientific article

Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B6 salvage pathway

scientific article

Serine hydroxymethyltransferase: a model enzyme for mechanistic, structural, and evolutionary studies

scientific article

Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism

scientific article

Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise

scientific article published in March 2010

Structural properties of the linkers connecting the N- and C- terminal domains in the MocR bacterial transcriptional regulators.

scientific article

Structure and mechanism of Escherichia coli pyridoxine 5'-phosphate oxidase

scientific article

Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase

scientific article

Structure of human erythrocyte catalase

scientific article

Structure-based mechanism for early PLP-mediated steps of rabbit cytosolic serine hydroxymethyltransferase reaction

scientific article published on 15 July 2013

Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor

scientific article

The MocR-like transcription factors: pyridoxal 5'-phosphate-dependent regulators of bacterial metabolism

scientific article published on 05 July 2018

The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

scientific article published on 02 October 2019

The multifaceted role of vitamin B6 in cancer: Drosophila as a model system to investigate DNA damage

scientific article published on 25 March 2020

Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications

scientific article published on April 2003

Vitamin B(6) salvage enzymes: mechanism, structure and regulation

scientific article published on 20 December 2010

X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with FMN at 1.8 A resolution

scientific article published in July 2000

X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution

scientific article

l-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subgroup of strictly related enzymes specialized for different functions

scientific article published on December 2001