List of works - Markus Eszlinger

A Newly Discovered TSHR Variant (L665F) Associated With Nonautoimmune Hyperthyroidism in an Austrian Family Induces Constitutive TSHR Activation by Steric Repulsion Between TM1 and TM7

scientific article published on 20 June 2014

A multi-gene approach to differentiate papillary thyroid carcinoma from benign lesions: gene selection using support vector machines with bootstrapping

scientific article

A two miRNA classifier differentiates follicular thyroid carcinomas from follicular thyroid adenomas.

scientific article

A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood

scientific article published on 6 August 2015

Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes

scientific article published on October 2001

Analysis options for high-throughput sequencing in miRNA expression profiling

scientific article

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

scientific article published on January 2010

Calcium signaling of thyrocytes is modulated by TSH through calcium binding protein expression

scientific article published on 18 January 2010

Cases of borderline in vitro constitutive thyrotropin receptor activity: how to decide whether a thyrotropin receptor mutation is constitutively active or not?

scientific article

Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis

scientific article

Clinical implications of molecular studies for the diagnosis of thyroid cancer.

scientific article published on January 2010

Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.

scientific article

Comparison of Color Flow Doppler Sonography (CFDS) and immunohistologic detection of microvessels for the assessment of the malignancy of thyroid nodules

scientific article published on 21 June 2010

Comparison of differential gene expression of hot and cold thyroid nodules with primary epithelial cell culture models by investigation of co-regulated gene sets

scientific article published on 4 January 2006

Complementary DNA expression array analysis suggests a lower expression of signal transduction proteins and receptors in cold and hot thyroid nodules

scholarly article

Current state and future perspective of molecular diagnosis of fine-needle aspiration biopsy of thyroid nodules

scientific article published on 18 May 2011

Cytology and mRNA expression analysis of fine needle aspirates of thyroid nodules in an East German region with borderline iodine deficiency.

scientific article

Detection of PAX8/PPARG and RET/PTC rearrangements is feasible in routine air-dried fine needle aspiration smears

scientific article published on October 2012

Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas

scientific article

Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinoma

scientific article published on 6 October 2011

Effect of iodine on early stage thyroid autonomy.

scientific article published on 28 October 2010

Evaluation of a Two-Year Routine Application of Molecular Testing of Thyroid Fine-Needle Aspirations Using a Seven-Gene Panel in a Primary Referral Setting in Germany

scientific article published on 10 January 2017

Evaluation of insulin-like growth factor II, cyclooxygenase-2, ets-1 and thyroid-specific thyroglobulin mRNA expression in benign and malignant thyroid tumours.

scientific article

Evaluation of peroxisome proliferator-activated receptor-gamma expression in benign and malignant thyroid pathologies.

scientific article

Evidence for a more pronounced effect of genetic predisposition than environmental factors on goitrogenesis by a case control study in an area with low normal iodine supply

scientific article published on 16 March 2011

Expression of regulators of g protein signaling mRNA is differentially regulated in hot and cold thyroid nodules

scientific article published on 01 November 2004

Fine-needle aspiration cytology of thyroid nodules: molecular diagnostics in a routine diagnostic setting

scientific article published on 25 February 2014

Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma.

scientific article published in December 2015

Gene Expression (mRNA) Markers for Differentiating between Malignant and Benign Follicular Thyroid Tumours

scientific article

Gene expression analysis reveals evidence for inactivation of the TGF-beta signaling cascade in autonomously functioning thyroid nodules

scientific article

Gene expression analysis reveals evidence for increased expression of cell cycle-associated genes and Gq-protein-protein kinase C signaling in cold thyroid nodules

scientific article

Growth factor expression in cold and hot thyroid nodules

scientific article published in February 2001

HED

scholarly article

High prevalence of TSHR/Gsα mutation-negative clonal hot thyroid nodules (HNs) in a Turkish cohort

scientific article published on 19 July 2011

Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes

scientific article published on January 2002

Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice

scientific article published on 01 October 2018

Impact of different methodologies on the detection of point mutations in routine air-dried fine needle aspiration (FNA) smears

scientific article

Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules.

scientific article published on 29 October 2013

Increased percentage of microvessels but decreased density of large vessels in papillary carcinomas as compared to hot and cold thyroid nodules.

scientific article published on 16 July 2009

Increased power of microarray analysis by use of an algorithm based on a multivariate procedure

scientific article published on 5 July 2005

Insights from molecular pathways: potential pharmacologic targets of benign thyroid nodules

scientific article published on October 2007

Inverse correlation of miRNA and cell cycle-associated genes suggests influence of miRNA on benign thyroid nodule tumorigenesis.

scientific article

Isoproterenol inhibits resistin gene expression through a G(S)-protein-coupled pathway in 3T3-L1 adipocytes

scientific article published on June 2001

Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas

scientific article published on December 2010

Laser capture microdissection is a valuable tool in the preoperative molecular screening of follicular lesions of the thyroid: an institutional experience.

scientific article published on 8 December 2014

Late manifestation of subclinical hyperthyroidism after goitrogenesis in an index patient with a N670S TSH receptor germline mutation masquerading as TSH receptor antibody negative Graves' disease.

scientific article published on 4 July 2012

Low Malignancy Rates in Fine-Needle Aspiration Cytologies in a Primary Care Setting in Germany

scientific article published on 6 October 2017

Meta- and reanalysis of gene expression profiles of hot and cold thyroid nodules and papillary thyroid carcinoma for gene groups

scientific article

Molecular Diagnosis Using Residual Liquid-Based Cytology Materials for Patients with Nondiagnostic or Indeterminate Thyroid Nodules.

scientific article published on 4 November 2016

Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP).

scientific article published on 2 February 2018

Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity.

scientific article

Molecular differential diagnosis of follicular thyroid carcinoma and adenoma based on gene expression profiling by using formalin-fixed paraffin-embedded tissues.

scientific article

Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns

scientific article published on 18 January 2010

Molecular pathogenesis of euthyroid and toxic multinodular goiter

scientific article

Molecular profiling of thyroid nodule fine-needle aspiration cytology

scientific article published on 31 March 2017

Molecular testing of thyroid fine-needle aspirations improves presurgical diagnosis and supports the histologic identification of minimally invasive follicular thyroid carcinomas.

scientific article published on 26 February 2015

Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors.

scientific article published on 12 March 2007

Perspectives for improved and more accurate classification of thyroid epithelial tumors

scientific article published on July 2008

Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation

scientific article published on 28 June 2016

Prolonged inappropriate TSH suppression during hypothyroidism after thyroid ablation in a patient with nonautoimmune familial hyperthyroidism

scientific article published on 17 May 2011

RGS 2 expression is regulated by TSH and inhibits TSH receptor signaling

scientific article

Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas

scientific article published on 08 August 2016

Ruling in or ruling out thyroid malignancy by molecular diagnostics of thyroid nodules

scientific article

Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.

scientific article published on 29 December 2010

Sialylation of human thyrotropin receptor improves and prolongs its cell-surface expression

scientific article published on 13 July 2005

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents.

scientific article published on 8 June 2014

Somatostatin receptor 2 expression determined by immunohistochemistry in cold thyroid nodules exceeds that of hot thyroid nodules, papillary thyroid carcinoma, and Graves' disease

scientific article published in May 2010

TERT Promoter Mutations in Papillary Thyroid Microcarcinomas.

scientific article published on 5 August 2015

TFF3-based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency.

scientific article

The Thyrotropin Receptor Mutation Database Update

scientific article published on 01 April 2020

The genetics of euthyroid familial goiter

scientific article

The leipzig thyrotropin receptor mutation database: update 2012.

scientific article published on 22 September 2012

Thyroglobulin mRNA quantification in the peripheral blood is not a reliable marker for the follow-up of patients with differentiated thyroid cancer

scientific article

Tobacco smoking differently influences cell types of the innate and adaptive immune system-indications from CpG site methylation

scientific article published on January 2015

Tumor necrosis factor alpha is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes

scientific article published on November 2001

Two-miRNA classifiers differentiate mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas in fine needle aspirations with high specificity.

scientific article

Young investigator challenge: Can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next-generation sequencing of thyroid FNA samples?

scientific article published on 26 September 2016

[Dignity of thyroid nodules: diagnostic gain by molecular fine needle aspiration cytology]

scientific article published on 24 September 2013

miRNAs with the potential to distinguish follicular thyroid carcinomas from benign follicular thyroid tumors: results of a meta-analysis.

scientific article published on 20 January 2014

List of works by Markus Eszlinger

A Newly Discovered TSHR Variant (L665F) Associated With Nonautoimmune Hyperthyroidism in an Austrian Family Induces Constitutive TSHR Activation by Steric Repulsion Between TM1 and TM7

A multi-gene approach to differentiate papillary thyroid carcinoma from benign lesions: gene selection using support vector machines with bootstrapping

A two miRNA classifier differentiates follicular thyroid carcinomas from follicular thyroid adenomas.

A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood

Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes

Analysis options for high-throughput sequencing in miRNA expression profiling

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

Calcium signaling of thyrocytes is modulated by TSH through calcium binding protein expression

Cases of borderline in vitro constitutive thyrotropin receptor activity: how to decide whether a thyrotropin receptor mutation is constitutively active or not?

Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis

Clinical implications of molecular studies for the diagnosis of thyroid cancer.

Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.

Comparison of Color Flow Doppler Sonography (CFDS) and immunohistologic detection of microvessels for the assessment of the malignancy of thyroid nodules

Comparison of differential gene expression of hot and cold thyroid nodules with primary epithelial cell culture models by investigation of co-regulated gene sets

Complementary DNA expression array analysis suggests a lower expression of signal transduction proteins and receptors in cold and hot thyroid nodules

Current state and future perspective of molecular diagnosis of fine-needle aspiration biopsy of thyroid nodules

Cytology and mRNA expression analysis of fine needle aspirates of thyroid nodules in an East German region with borderline iodine deficiency.

Detection of PAX8/PPARG and RET/PTC rearrangements is feasible in routine air-dried fine needle aspiration smears

Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas

Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinoma

Effect of iodine on early stage thyroid autonomy.

Evaluation of a Two-Year Routine Application of Molecular Testing of Thyroid Fine-Needle Aspirations Using a Seven-Gene Panel in a Primary Referral Setting in Germany

Evaluation of insulin-like growth factor II, cyclooxygenase-2, ets-1 and thyroid-specific thyroglobulin mRNA expression in benign and malignant thyroid tumours.

Evaluation of peroxisome proliferator-activated receptor-gamma expression in benign and malignant thyroid pathologies.

Evidence for a more pronounced effect of genetic predisposition than environmental factors on goitrogenesis by a case control study in an area with low normal iodine supply

Expression of regulators of g protein signaling mRNA is differentially regulated in hot and cold thyroid nodules

Fine-needle aspiration cytology of thyroid nodules: molecular diagnostics in a routine diagnostic setting

Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma.

Gene Expression (mRNA) Markers for Differentiating between Malignant and Benign Follicular Thyroid Tumours

Gene expression analysis reveals evidence for inactivation of the TGF-beta signaling cascade in autonomously functioning thyroid nodules

Gene expression analysis reveals evidence for increased expression of cell cycle-associated genes and Gq-protein-protein kinase C signaling in cold thyroid nodules

Growth factor expression in cold and hot thyroid nodules

HED

High prevalence of TSHR/Gsα mutation-negative clonal hot thyroid nodules (HNs) in a Turkish cohort

Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes

Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice

Impact of different methodologies on the detection of point mutations in routine air-dried fine needle aspiration (FNA) smears

Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules.

Increased percentage of microvessels but decreased density of large vessels in papillary carcinomas as compared to hot and cold thyroid nodules.

Increased power of microarray analysis by use of an algorithm based on a multivariate procedure

Insights from molecular pathways: potential pharmacologic targets of benign thyroid nodules

Inverse correlation of miRNA and cell cycle-associated genes suggests influence of miRNA on benign thyroid nodule tumorigenesis.

Isoproterenol inhibits resistin gene expression through a G(S)-protein-coupled pathway in 3T3-L1 adipocytes

Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas

Laser capture microdissection is a valuable tool in the preoperative molecular screening of follicular lesions of the thyroid: an institutional experience.

Late manifestation of subclinical hyperthyroidism after goitrogenesis in an index patient with a N670S TSH receptor germline mutation masquerading as TSH receptor antibody negative Graves' disease.

Low Malignancy Rates in Fine-Needle Aspiration Cytologies in a Primary Care Setting in Germany

Meta- and reanalysis of gene expression profiles of hot and cold thyroid nodules and papillary thyroid carcinoma for gene groups

Molecular Diagnosis Using Residual Liquid-Based Cytology Materials for Patients with Nondiagnostic or Indeterminate Thyroid Nodules.

Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP).

Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity.

Molecular differential diagnosis of follicular thyroid carcinoma and adenoma based on gene expression profiling by using formalin-fixed paraffin-embedded tissues.

Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns

Molecular pathogenesis of euthyroid and toxic multinodular goiter

Molecular profiling of thyroid nodule fine-needle aspiration cytology

Molecular testing of thyroid fine-needle aspirations improves presurgical diagnosis and supports the histologic identification of minimally invasive follicular thyroid carcinomas.

Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors.

Perspectives for improved and more accurate classification of thyroid epithelial tumors

Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation

Prolonged inappropriate TSH suppression during hypothyroidism after thyroid ablation in a patient with nonautoimmune familial hyperthyroidism

RGS 2 expression is regulated by TSH and inhibits TSH receptor signaling

Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas

Ruling in or ruling out thyroid malignancy by molecular diagnostics of thyroid nodules

Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.

Sialylation of human thyrotropin receptor improves and prolongs its cell-surface expression

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents.

Somatostatin receptor 2 expression determined by immunohistochemistry in cold thyroid nodules exceeds that of hot thyroid nodules, papillary thyroid carcinoma, and Graves' disease

TERT Promoter Mutations in Papillary Thyroid Microcarcinomas.

TFF3-based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency.

The Thyrotropin Receptor Mutation Database Update

The genetics of euthyroid familial goiter

The leipzig thyrotropin receptor mutation database: update 2012.

Thyroglobulin mRNA quantification in the peripheral blood is not a reliable marker for the follow-up of patients with differentiated thyroid cancer

Tobacco smoking differently influences cell types of the innate and adaptive immune system-indications from CpG site methylation

Tumor necrosis factor alpha is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes

Two-miRNA classifiers differentiate mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas in fine needle aspirations with high specificity.

Young investigator challenge: Can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next-generation sequencing of thyroid FNA samples?

[Dignity of thyroid nodules: diagnostic gain by molecular fine needle aspiration cytology]

miRNAs with the potential to distinguish follicular thyroid carcinomas from benign follicular thyroid tumors: results of a meta-analysis.