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List of works by Chae-Ok Yun

A cyclic RGD-coated peptide nanoribbon as a selective intracellular nanocarrier

scientific article

A hypoxia- and {alpha}-fetoprotein-dependent oncolytic adenovirus exhibits specific killing of hepatocellular carcinomas

scientific article published on December 2010

A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGFbeta signaling for breast cancer therapy

scientific article

A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene

scientific journal article

A novel combination treatment of armed oncolytic adenovirus expressing IL-12 and GM-CSF with radiotherapy in murine hepatocarcinoma

scientific article

A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer

scientific article

A novel three-dimensional model system for keloid study: organotypic multicellular scar model

scientific article published on 11 December 2012

A proteoliposome containing apolipoprotein A-I mutant (V156K) enhances rapid tumor regression activity of human origin oncolytic adenovirus in tumor-bearing zebrafish and mice.

scientific article

A review of RGD-functionalized nonviral gene delivery vectors for cancer therapy

scientific article published on 28 September 2012

A single adenovirus-mediated relaxin delivery attenuates established liver fibrosis in rats

scientific article

A vesicular stomatitis virus glycoprotein epitope-incorporated oncolytic adenovirus overcomes CAR-dependency and shows markedly enhanced cancer cell killing and suppression of tumor growth.

scientific article published on 26 September 2015

ADP-overexpressing adenovirus elicits enhanced cytopathic effect by induction of apoptosis

scientific article published in January 2005

Acquired resistance to cetuximab is mediated by increased PTEN instability and leads cross-resistance to gefitinib in HCC827 NSCLC cells.

scientific article

Active targeting and safety profile of PEG-modified adenovirus conjugated with herceptin.

scientific article published on 11 January 2011

Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA.

scientific article

Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner

scientific article published on October 2003

Adenovirus expressing dual c-Met-specific shRNA exhibits potent antitumor effect through autophagic cell death accompanied by senescence-like phenotypes in glioblastoma cells

scientific article published on February 2015

Adenovirus-relaxin gene therapy for keloids: implication for reversing pathological fibrosis

scientific article published in September 2011

Anionic clay as the drug delivery vehicle: tumor targeting function of layered double hydroxide-methotrexate nanohybrid in C33A orthotopic cervical cancer model

scientific article

Antitumor effect and safety profile of systemically delivered oncolytic adenovirus complexed with EGFR-targeted PAMAM-based dendrimer in orthotopic lung tumor model.

scientific article

Antitumoral effects of recombinant adenovirus YKL-1001, conditionally replicating in alpha-fetoprotein-producing human liver cancer cells

scientific article published in June 2002

Application of ecological and mathematical theory to cancer: New challenges

scientific article published in December 2015

Assessment of angiogenesis of hepatocellular carcinoma using dynamic contrast enhanced MR and histopathologic correlation in an experimental rat model.

scientific article published in March 2014

Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation

scientific article

Bioreducible polymer-conjugated oncolytic adenovirus for hepatoma-specific therapy via systemic administration

scientific article published on 16 September 2011

Bypassing immunization: optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA.

scientific article

CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer

scientific article published on 16 November 2015

Capacitance-based real time monitoring of receptor-mediated endocytosis

scientific article published on 27 October 2009

Combination of radiotherapy and adenovirus-mediated p53 gene therapy for MDM2-overexpressing hepatocellular carcinoma

scientific article

Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model.

scientific article published on 6 May 2016

Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect.

scientific article published on 9 March 2006

Coxsackie and adenovirus receptor binding ablation reduces adenovirus liver tropism and toxicity

scientific article

Current advances in adenovirus nanocomplexes: more specificity and less immunogenicity

scientific article published on December 2010

De novo osteogenesis from human ligamentum flavum by adenovirus-mediated bone morphogenetic protein-2 gene transfer

scientific article published on December 2005

Decorin-expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids.

scientific article published on 8 May 2015

Del-1 overexpression potentiates lung cancer cell proliferation and invasion

scientific article published on 3 November 2015

Development of a Conditional Replication Competent Adenovirus, Controlled by the Human Telomerase Promoter (hTERT)

scientific article published on 01 June 2003

Development of porous PLGA/PEI1.8k biodegradable microspheres for the delivery of mesenchymal stem cells (MSCs).

scientific article

Direct observation of interactions of silk-elastinlike protein polymer with adenoviruses and elastase

scientific article published on 22 April 2015

Distinct roles of DKK1 and DKK2 in tumor angiogenesis

scientific article published on 04 October 2013

Double E1B 19 kDa- and E1B 55 kDa-deleted oncolytic adenovirus in combination with radiotherapy elicits an enhanced anti-tumor effect

scientific article

Down-regulation of collagen synthesis and matrix metalloproteinase expression in myofibroblasts from Dupuytren nodule using adenovirus-mediated relaxin gene therapy.

scientific article

Dual tumor targeting with pH-sensitive and bioreducible polymer-complexed oncolytic adenovirus.

scientific article published on 05 December 2014

E1A- and E1B-Double mutant replicating adenovirus elicits enhanced oncolytic and antitumor effects

scientific article published on September 2007

Effect of Function-Enhanced Mesenchymal Stem Cells Infected With Decorin-Expressing Adenovirus on Hepatic Fibrosis

scientific article published on 30 June 2016

Effect of Relaxin Expression from an Alginate Gel-Encapsulated Adenovirus on Scar Remodeling in a Pig Model

scientific article published on 01 September 2019

Effect of decorin on overcoming the extracellular matrix barrier for oncolytic virotherapy

scientific article

Effects of Human Mesenchymal Stem Cells Transduced with Superoxide Dismutase on Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice.

scientific article published on 14 October 2015

Effects of the knockdown of hypoxia inducible factor-1α expression by adenovirus-mediated shRNA on angiogenesis and tumor growth in hepatocellular carcinoma cell lines.

scientific article published on September 2010

Efficient gene transfer of VSV-G pseudotyped retroviral vector to human brain tumor

scientific article published in February 2001

Efficient lung orthotopic tumor-growth suppression of oncolytic adenovirus complexed with RGD-targeted bioreducible polymer

scientific article published on 6 March 2014

Endothelial-to-mesenchymal transition induced by Wnt 3a in keloid pathogenesis.

scientific article

Enhanced anti-tumor efficacy and safety profile of tumor microenvironment-responsive oncolytic adenovirus nanocomplex by systemic administration

scientific article published on 10 September 2015

Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model

scientific article published in October 2006

Enhanced antitumor immunotherapeutic effect of B-cell-based vaccine transduced with modified adenoviral vector containing type 35 fiber structures

scientific article published on 14 November 2013

Enhanced delivery of adenovirus, using proteoliposomes containing wildtype or V156K apolipoprotein A-I and dimyristoylphosphatidylcholine

scientific article published in May 2010

Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance

scientific article published on 23 August 2012

Enhanced therapeutic efficacy of an adenovirus-PEI-bile-acid complex in tumors with low coxsackie and adenovirus receptor expression

scientific article published on 13 April 2014

Enhancing the therapeutic efficacy of adenovirus in combination with biomaterials.

scientific article published on 3 December 2011

Erratum to: Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model

scientific article published on 17 June 2016

Erratum: Oh, E., et al. Cryopreserved Human Natural Killer Cells Exhibit Potent Antitumor Efficacy against Orthotopic Pancreatic Cancer through Efficient Tumor-Homing and Cytolytic Ability (Running Title: Cryopreserved NK Cells Exhibit Antitumor Eff

scientific article published on 04 November 2020

Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy.

scientific article published in September 2002

Evaluation of E1B-mutant Replicating Adenoviruses for Cancer Gene Therapy

scientific article published on 01 December 2001

Evolution of oncolytic adenovirus for cancer treatment

scientific article published on 24 December 2011

Evolving lessons on nanomaterial-coated viral vectors for local and systemic gene therapy

scientific article published on 27 June 2016

Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy

scientific article published on 11 April 2013

Extramarginal excision is preferable for hypertrophic scars.

scientific article

Fabrication of cross-linked alginate beads using electrospraying for adenovirus delivery

scientific article published on 2 February 2012

Functional significance of point mutations in stress chaperone mortalin and their relevance to Parkinson disease.

scientific article

Gene therapy using hepatocyte growth factor expressing adenovirus improves skin flap survival in a rat model.

scientific article

Generation of a rabbit V(H) domain antibody polyspecific to c-Met and adenoviral knob protein

scientific article published on 15 November 2005

Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model.

scientific article

Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts.

scientific article

Hepatoma targeting peptide conjugated bio-reducible polymer complexed with oncolytic adenovirus for cancer gene therapy

scientific article

Human Noxin is an anti-apoptotic protein in response to DNA damage of A549 non-small cell lung carcinoma

scientific article

Human relaxin gene expression delivered by bioreducible dendrimer polymer for post-infarct cardiac remodeling in rats

scientific article published on 26 April 2016

Identification and functional characterization of nuclear mortalin in human carcinogenesis.

scientific article

Impaired nonhomologous end-joining in mismatch repair-deficient colon carcinomas

scientific article

Increased Cytopathic Effect of Replicating Adenovirus Expressing Adenovirus Death Protein

scientific article

Inhibition of tumour angiogenesis and growth by small hairpin HIF-1α and IL-8 in hepatocellular carcinoma

scientific article published on 9 December 2013

Inorganic nanovehicle targets tumor in an orthotopic breast cancer model.

scientific article published on 21 March 2014

Ionically crosslinked Ad/chitosan nanocomplexes processed by electrospinning for targeted cancer gene therapy

scientific article published on 15 July 2010

KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A.

scientific article published on 17 January 2012

Linearized oncolytic adenoviral plasmid DNA delivered by bioreducible polymers ⬇️

scientific article published on December 20, 2011

Markedly enhanced cytolysis by E1B-19kD-deleted oncolytic adenovirus in combination with cisplatin

scientific article published on April 2006

MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3' untranslated region

scientific article

Molecular characterization of apoptosis induced by CARF silencing in human cancer cells

scientific article published on 5 November 2010

Multifunctional nanoparticles for targeted chemophotothermal treatment of cancer cells

scientific article published on 30 June 2011

Nanoisland-based random activation of fluorescence for visualizing endocytotic internalization of adenovirus

scientific article published on 01 June 2010

Negative Regulation-Resistant p53 Variant Enhances Oncolytic Adenoviral Gene Therapy ⬇️

scientific article published on February 21, 2012

Novel cancer antiangiotherapy using the VEGF promoter-targeted artificial zinc-finger protein and oncolytic adenovirus.

scientific article

Oncolytic Ad co-expressing decorin and Wnt decoy receptor overcomes chemoresistance of desmoplastic tumor through degradation of ECM and inhibition of EMT

scientific article published on 29 May 2019

Oncolytic Adenovirus Coated with Multidegradable Bioreducible Core-Cross-Linked Polyethylenimine for Cancer Gene Therapy

scientific article

Oncolytic Viruses and Immune Checkpoint Inhibitors: Preclinical Developments to Clinical Trials

scientific article published on 16 November 2020

Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ2 or IL-18Rα.

scientific article

Oncolytic adenovirus expressing IL-23 and p35 elicits IFN-γ- and TNF-α-co-producing T cell-mediated antitumor immunity

scientific article published on 03 July 2013

Oncolytic potential of E1B 55 kDa-deleted YKL-1 recombinant adenovirus: correlation with p53 functional status

scientific article

Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF.

scientific article

Polymeric oncolytic adenovirus for cancer gene therapy

scientific article

Potent and long-term antiangiogenic efficacy mediated by FP3-expressing oncolytic adenovirus

scientific article published on 5 May 2015

Potent antitumor effect of neurotensin receptor-targeted oncolytic adenovirus co-expressing decorin and Wnt antagonist in an orthotopic pancreatic tumor model

scientific article published on 12 October 2015

Potent antitumor effect of tumor microenvironment-targeted oncolytic adenovirus against desmoplastic pancreatic cancer

scientific article published on 20 September 2017

Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1.

scientific article published on 25 February 2009

Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics

scientific article published on August 2015

RGD peptide-modified adenovirus expressing hepatocyte growth factor and X-linked inhibitor of apoptosis improves islet transplantation.

scientific article published on December 2011

Recent developments in oncolytic adenovirus-based immunotherapeutic agents for use against metastatic cancers

scientific article published on 11 January 2013

Redirecting adenovirus tropism by genetic, chemical, and mechanical modification of the adenovirus surface for cancer gene therapy.

scientific article published on 11 March 2016

Regulation of the cyclin-dependent kinase inhibitor 1A gene (CDKN1A) by the repressor BOZF1 through inhibition of p53 acetylation and transcription factor Sp1 binding.

scientific article published on 17 January 2013

Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy

scientific article published in October 2006

Relaxin-expressing adenovirus decreases collagen synthesis and up-regulates matrix metalloproteinase expression in keloid fibroblasts: in vitro experiments

scientific article published on September 2012

Relaxin-expressing oncolytic adenovirus induces remodeling of physical and immunological aspects of cold tumor to potentiate PD-1 blockade

scientific article published on 01 August 2020

Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice

scientific article published on May 2007

Retargeting of adenoviral gene delivery via Herceptin-PEG-adenovirus conjugates to breast cancer cells.

scientific article published on 15 August 2007

Retrovirally transduced NCAM140 facilitates neuronal fate choice of hippocampal progenitor cells

scientific article published in July 2005

Role of promyelocytic leukemia zinc finger (PLZF) in cell proliferation and cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) gene repression

scientific article

Rosiglitazone inhibits early stage of glucolipotoxicity-induced beta-cell apoptosis.

scientific article

Safety profiles and antitumor efficacy of oncolytic adenovirus coated with bioreducible polymer in the treatment of a CAR negative tumor model

scientific article

Short hairpin RNA-expressing oncolytic adenovirus-mediated inhibition of IL-8: effects on antiangiogenesis and tumor growth inhibition

scientific article published on 14 February 2008

Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin.

scientific article

Soluble vascular endothelial growth factor decoy receptor FP3 exerts potent antiangiogenic effects

scientific article

Strategies to increase drug penetration in solid tumors

scientific article published on 26 July 2013

Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF.

scientific article published on 13 October 2011

Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.

scientific article published on 9 March 2016

Stress chaperone mortalin regulates human melanogenesis.

scientific article

Stronger proteasomal inhibition and higher CHOP induction are responsible for more effective induction of paraptosis by dimethoxycurcumin than curcumin.

scientific article published on 13 March 2014

Suicide cancer gene therapy using pore-forming toxin, streptolysin O.

scientific article published in June 2006

Sustained local delivery of oncolytic short hairpin RNA adenoviruses for treatment of head and neck cancer

scientific article

Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases

scientific article

Systemic administration of human mesenchymal stromal cells infected with polymer-coated oncolytic adenovirus induces efficient pancreatic tumor homing and infiltration

scientific article published on 06 May 2019

TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis.

scientific article published on 5 May 2015

Targeting delivery of tocopherol and doxorubicin grafted-chitosan polymeric micelles for cancer therapy: In vitro and in vivo evaluation

scientific article published on 16 June 2015

Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors

scientific article

The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells

scientific article

The effect of surface modification of adenovirus with an arginine-grafted bioreducible polymer on transduction efficiency and immunogenicity in cancer gene therapy

scientific article

Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.

scientific article

Therapeutic efficacy of a systemically delivered oncolytic adenovirus - biodegradable polymer complex

scientific article published on 27 March 2013

Therapeutic targeting of chitosan-PEG-folate-complexed oncolytic adenovirus for active and systemic cancer gene therapy

scientific article published on 4 April 2013

Treatment strategies for combining immunostimulatory oncolytic virus therapeutics with dendritic cell injections

scientific article published on December 2015

Tumor suppression by apoptotic and anti-angiogenic effects of mortalin-targeting adeno-oncolytic virus

scientific article published on July 2010

Tumor targeted adenovirus nanocomplex ionically crosslinked by chitosan

scientific article published on November 2010

Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1.

scientific article

Tumor-targeted radionuclide imaging and therapy based on human sodium iodide symporter gene driven by a modified telomerase reverse transcriptase promoter

scientific article published on September 2008

Tuning Surface Charge and PEGylation of Biocompatible Polymers for Efficient Delivery of Nucleic Acid or Adenoviral Vector

scientific article

Using a magnetic field to redirect an oncolytic adenovirus complexed with iron oxide augments gene therapy efficacy

scientific article published on 2 July 2015

Utilizing adenovirus vectors for gene delivery in cancer

scientific article published on 07 January 2014

VEGF-specific short hairpin RNA-expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth.

scientific article published on February 2007

Vascular endothelial growth factor (VEGF) signaling regulates hippocampal neurons by elevation of intracellular calcium and activation of calcium/calmodulin protein kinase II and mammalian target of rapamycin

scientific journal article

Viral IL-10 gene transfer prolongs rat islet allograft survival

scientific article published in January 2008

Viral genome DNA/lipoplexes elicit in situ oncolytic viral replication and potent antitumor efficacy via systemic delivery

scientific article published on 14 June 2011

Withanone-rich combination of Ashwagandha withanolides restricts metastasis and angiogenesis through hnRNP-K.

scientific article published on 18 September 2014

Z-FA-FMK as a novel potent inhibitor of reovirus pathogenesis and oncolysis in vivo

scientific article published on January 2010

ZBTB2, a novel master regulator of the p53 pathway.

scientific article

dl-VSVG-LacZ, a vesicular stomatitis virus glycoprotein epitope-incorporated adenovirus, exhibits marked enhancement in gene transduction efficiency.

scientific article published in November 2003

pH-sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis

scientific article published on 7 January 2015

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