Search filters

List of works by Minyong Li

1,2,3-Triazole Bound Au(I) (TA-Au) as Chemoselective Catalysts in Promoting Asymmetric Synthesis of Substituted Allenes

scientific article published on 19 April 2011

3D-QSAR study on a series of Bcl-2 protein inhibitors using comparative molecular field analysis

scientific article published in May 2011

A Fluorescent Hydrogen Peroxide Probe Based on a 'Click' Modified Coumarin Fluorophore

scientific article

A benzothiazole-based fluorescent probe for thiol bioimaging

A bestatin-based fluorescent probe for aminopeptidase N cell imaging

A coelenterazine-type bioluminescent probe for nitroreductase imaging

scientific article

A comparison of different electrostatic potentials on prediction accuracy in CoMFA and CoMSIA studies

A fast and simple approach to the quantitative evaluation of fibrinogen coagulation

scientific article published on 8 October 2013

A fluorescent probe for imaging p53-MDM2 protein-protein interaction

scientific article published on 10 October 2014

A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice

scientific article published on 11 January 2018

A new boronic acid based fluorescent reporter for catechol

article

A new phenothiazine structural scaffold as inhibitors of bacterial quorum sensing in Vibrio harveyi

scientific article published on 4 March 2009

A novel NBD-based pH “on–off” fluorescent probe equipped with the N-phenylpiperazine group for lysosome imaging

scholarly article in RSC Advances, vol. 6 no. 104, 2016

A novel coelenterate luciferin-based luminescent probe for selective and sensitive detection of thiophenols

scientific article published on 17 October 2016

A novel pH “off–on” fluorescent probe for lysosome imaging

scholarly article in RSC Advances, vol. 3 no. 32, 2013

A novel structure-based virtual screening model for the hERG channel blockers

article

A specific and selective chemiluminescent probe for Pd 2+ detection

article published in 2018

A unique quinolineboronic acid-based supramolecular structure that relies on double intermolecular B-N bonds for self-assembly in solid state and in solution.

scientific article

Advances and perspectives in cell-specific aptamers

scientific article published on January 2011

Alignment-independent QSAR analysis of SecA inhibitors

scientific article published in July 2013

Aptamer-based carbohydrate recognition

scientific article published on January 2010

Astemizole Derivatives as Fluorescent Probes for hERG Potassium Channel Imaging

scientific article published on 20 January 2016

Astemizole-based turn-on fluorescent probes for imaging hERG potassium channel

scientific article published on 26 February 2019

Bifunctional fluorescent probes for hydrogen peroxide and diols based on a 1,8-naphthalimide fluorophore

BioLeT: A new design strategy for functional bioluminogenic probes

Biodegradable Polymer Nanoparticles for Photodynamic Therapy by Bioluminescence Resonance Energy Transfer

scientific article

Bioluminescence Imaging of Selenocysteine in Vivo with a Highly Sensitive Probe

scientific article published on 20 November 2019

Bioluminescence Probe for Detecting Hydrogen Sulfide in Vivo

scientific article published on 4 December 2015

Bioluminescence probe for γ-glutamyl transpeptidase detection in vivo

scientific article published on 14 November 2017

Bioluminescent Probe for Detecting Mercury(II) in Living Mice

scientific article published on 15 July 2016

Bioluminescent Probe for Detection of Starvation-Induced Pantetheinase Upregulation

scientific article published on 18 July 2018

Bioluminescent Probe for Monitoring Endogenous Fibroblast Activation Protein-Alpha

scientific article published on 11 November 2019

Bioluminescent Probe for Tumor Hypoxia Detection via CYP450 Reductase in Living Animals

scientific article published on 27 October 2017

Bioluminescent probe for detecting endogenous hypochlorite in living mice

scientific article published on 5 January 2018

Bioluminescent probe for hydrogen peroxide imaging in vitro and in vivo

scientific article published on 17 September 2014

Bioluminogenic Imaging of AminopeptidaseN In Vitro and In Vivo

scientific article published on 01 January 2016

Boronate Can Be the Fluorogenic Switch for the Detection of Hydrogen Peroxide

scientific article published on January 1, 2012

CONVENIENT AND RAPID PREPARATION OF INDENE DIMERS FROM INDENES OR INDANOLS

Cage the firefly luciferin! – a strategy for developing bioluminescent probes

scientific article published on January 21, 2013

Carbohydrate biomarkers for future disease detection and treatment

scientific article published on 07 February 2010

Carbohydrate recognition by boronolectins, small molecules, and lectins

scientific article

Cell and in vivo imaging of fluoride ion with highly selective bioluminescent probes

scientific article published on 2 September 2015

Characterization of binding site of closed-state KCNQ1 potassium channel by homology modeling, molecular docking, and pharmacophore identification

scientific article published on 01 July 2005

ChemInform Abstract: 1,2,3-Triazole Bound Au(I) (TA-Au) as Chemoselective Catalysts in Promoting Asymmetric Synthesis of Substituted Allenes

ChemInform Abstract: Cage the Firefly Luciferin! - A Strategy for Developing Bioluminescent Probes

ChemInform Abstract: Fluoride Protects Boronic Acids in the Copper(I)-Mediated Click Reaction

ChemInform Abstract: Inhibitors and Antagonists of Bacterial Quorum Sensing

ChemInform Abstract: Novel Antileukemic Agents Derived from Tamibarotene and Nitric Oxide Donors

Chemical validation of phosphodiesterase C as a chemotherapeutic target in Trypanosoma cruzi, the etiological agent of Chagas' disease

scientific article published on 12 July 2010

Computational studies of H5N1 hemagglutinin binding with SA-α-2, 3-Gal and SA-α-2, 6-Gal

scientific article published in 2006

Computational studies of the binding site of alpha1A-adrenoceptor antagonists

scientific article published on 15 July 2008

Computer-based de novo design, synthesis, and evaluation of boronic acid-based artificial receptors for selective recognition of dopamine

scientific article

Corrigendum to “A unique quinolineboronic acid-based supramolecular structure that relies on double intermolecular B–N bonds for self-assembly in solid state and in solution”

scholarly article published in Tetrahedron

Coumarin-based Fluorescent Probes for H2S Detection

scientific article published on September 23, 2012

Density functional theory based quantitative structure-property relationship studies on coumarin-based prodrugs

scientific article published on 01 October 2012

Design and Synthesis of New Heterocyclic Bcr-Abl Inhibitors

Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA.

scientific article

Design of OFF/ON fluorescent thiol probes based on coumarin fluorophore

Design strategy for photoinduced electron transfer-based small-molecule fluorescent probes of biomacromolecules

scientific article published on June 2014

Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors

scientific article published on 17 February 2011

Design, synthesis and biological evaluation of 4-chromanone derivatives as IKr inhibitors

scientific article published on 01 April 2014

Design, synthesis and biological evaluation of naphthalimide-based fluorescent probes for α1-adrenergic receptors.

scientific article published in February 2014

Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors

scientific article

Design, synthesis and preliminary activity evaluation of novel L-lysine derivatives as aminopeptidase N/CD13 inhibitors

scientific article

Design, synthesis and preliminary biological evaluation of indole-3-carboxylic acid-based skeleton of Bcl-2/Mcl-1 dual inhibitors

scientific article published on 11 February 2017

Design, synthesis, and structure-activity relationship, molecular modeling, and NMR studies of a series of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors

scientific article published on December 2008

Discovering the Binding Modes of Natural Products with Histone Deacetylase 1

Discovering the binding modes of natural products with histone deacetylase 1.

scientific article published in February 2013

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

scientific article

Discovery of Bioluminogenic Probes for Aminopeptidase N Imaging

scientific article published on 12 February 2014

Discovery of Environment-Sensitive Fluorescent Agonists for α1-Adrenergic Receptors

scientific article published on 30 July 2019

Discovery of Fluorescence Polarization Probe for the ELISA-Based Antagonist Screening of α1-Adrenergic Receptors

scientific article

Discovery of New Substrates forLuxABBacterial Bioluminescence

scientific article published on 21 March 2016

Discovery of Nonpeptide, Environmentally Sensitive Fluorescent Probes for Imaging p53-MDM2 Interactions in Living Cell Lines and Tissue Slice

scientific article published on 22 January 2020

Discovery of Quinazoline-Based Fluorescent Probes to α1-Adrenergic Receptors

scientific article published on 30 March 2015

Discovery of Small-Molecule Sulfonamide Fluorescent Probes for GPR120

scientific article published on 15 November 2019

Discovery of Turn-On Fluorescent Probes for Detecting Bcl-2 Protein

scientific article published on 21 March 2019

Discovery of a Pair of Diastereomers as Potent HDACs Inhibitors: Determination of Absolute Configuration, Biological Activity Comparison and Computational Study

scientific article

Discovery of a Turn-On Fluorescent Probe for Myeloid Cell Leukemia-1 Protein

scientific article published on 12 October 2017

Discovery of a novel histone deacetylase 8 inhibitor by virtual screening

Discovery of a series of 2-phenylnaphthalenes as firefly luciferase inhibitors

scholarly article in RSC Advances, vol. 5 no. 78, 2015

Discovery of naphthalimide conjugates as fluorescent probes for α 1 -adrenoceptors

Discovery of the First Environment-Sensitive Fluorescent Probe for GPR120 (FFA4) Imaging

scientific article published on 27 March 2017

Discovery of the First Environment-Sensitive Near-Infrared (NIR) Fluorogenic Ligand for α1-Adrenergic Receptors Imaging in Vivo

scientific article published on 28 January 2016

Discovery of the first SecA inhibitors using structure-based virtual screening

scientific article

Drug discoveries towards Kv1.5 potassium channel

scientific article published in January 2009

Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling.

scientific article published on 15 March 2017

Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8.

scientific article

Environment-Sensitive Fluorescent Probe for the Human Ether-a-go-go-Related Gene Potassium Channel

scientific article published on 5 January 2016

Environment-sensitive turn-on fluorescent probes for p53-MDM2 protein-protein interaction

article published in 2017

Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy

scientific article published on 8 August 2010

FFA4 receptor (GPR120): A hot target for the development of anti-diabetic therapies

scientific article published on 26 June 2015

Facile synthesis of fluorescent active triazapentalenes through gold-catalyzed triazole-alkyne cyclization

scientific article published on July 2014

Fluorescein analogues inhibit SecA ATPase: the first sub-micromolar inhibitor of bacterial protein translocation

scientific article published on 22 February 2012

Fluorescence triggered by ligand-protein hydrophobic interaction

Fluoride protects boronic acids in the copper(i)-mediated click reaction

scientific article published on 06 August 2009

Fluorogenic probe for the human Ether-a-Go-Go-Related Gene potassium channel imaging

scientific article

Homology modeling and examination of the effect of the D92E mutation on the H5N1 nonstructural protein NS1 effector domain

scientific article published on 5 October 2007

Homology modeling, molecular dynamic simulation and docking studies of cyclin dependent kinase 1.

scientific article

How to Improve Docking Accuracy of AutoDock4.2: A Case Study Using Different Electrostatic Potentials

scientific article published on 02 January 2013

How to generate reliable and predictive CoMFA models

scientific article published on January 2011

Identification of AI-2 Quorum Sensing Inhibitors in Vibrio harveyi Through Structure-Based Virtual Screening

scientific article published in January 2018

Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi

scientific article published in 2008

Identification of the first fluorescent alpha-amidoboronic acids that change fluorescent properties upon sugar binding

scientific article published on 08 February 2009

Improved antiproliferative activities of a new series of 1,3,4-thiadiazole derivatives against human leukemia and breast cancer cell lines

In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

scientific article published on 28 March 2018

In silico binding characteristics between human histamine H1 receptor and antagonists

scientific article published on 24 February 2010

Inhibiting Firefly Bioluminescence by Chalcones

scientific article

Inhibition of Quorum Sensing inVibrio harveyiby Boronic Acids

scientific article published on 01 July 2009

Inhibitors and antagonists of bacterial quorum sensing

scientific article published on January 2009

Inside Back Cover: Fluorescein Analogues Inhibit SecA ATPase: The First Sub-micromolar Inhibitor of Bacterial Protein Translocation (ChemMedChem 4/2012)

scholarly article by Ying-Ju Huang et al published 27 March 2012 in ChemMedChem

Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.

scientific article

Intermolecular Homopropargyl Alcohol Addition to Alkyne and a Sequential 1,6-Enyne Cycloisomerization with Triazole-Gold Catalyst

article

LYP3, a new bestatin derivative for aminopeptidase N inhibition.

scientific article published on January 2011

Lighting up GPCRs with a fluorescent multiprobe dubbed "Snifit".

scientific article published on 9 January 2013

Lighting up bioluminescence with coelenterazine: strategies and applications

scientific article published on 24 March 2016

Luminescence of coelenterazine derivatives with C-8 extended electronic conjugation

article published in 2016

Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase

scientific article

Modeling the binding modes of Kv1.5 potassium channel and blockers

scientific article published on 10 April 2008

Modeling the excitation wavelengths (lambda(ex)) of boronic acids

scientific article published on 20 March 2008

Modeling the interactions between alpha(1)-adrenergic receptors and their antagonists

scientific article published on September 2010

Molecular hybridization, synthesis, and biological evaluation of novel chroman I(Kr) and I(Ks) dual blockers

scientific article published on 14 January 2009

Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphatase

scientific article published on 31 October 2013

N-2-aryl-1,2,3-triazoles: a novel class of UV/blue-light-emitting fluorophores with tunable optical properties

scientific article published on 22 March 2011

Naphthalimide-based fluorescent off/on probes for the detection of thiols

article published in 2012

New bioluminescent coelenterazine derivatives with various C-6 substitutions.

scientific article

Novel AI-2 quorum sensing inhibitors in Vibrio harveyi identified through structure-based virtual screening.

scientific article

Novel aminopeptidase N (APN/CD13) inhibitors derived from 3-phenylalanyl-N'-substituted-2,6-piperidinedione

scientific article published on 26 June 2010

Novel antileukemic agents derived from tamibarotene and nitric oxide donors

scientific article published on 01 October 2011

Novel bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution for Renilla luciferase.

scientific article

Novel intramolecular photoinduced electron transfer-based probe for the Human Ether-a-go-go-Related Gene (hERG) potassium channel

scientific article

Optical probes, theranostics and optogenetics shed light on zebrafish (Danio rerio)

Optogenetic Control of Voltage-Gated Calcium Channels

scientific article published on 23 March 2018

Pharmacophore Mapping for Kv1.5 Potassium Channel Blockers

Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy

scientific article published on 15 September 2020

Pharmacophore identification of alpha(1A)-adrenoceptor antagonists

scientific article published in February 2005

Pharmacophore-based design, synthesis, biological evaluation, and 3D-QSAR studies of aryl-piperazines as alpha(1)-adrenoceptor antagonists

scientific article published in July 2005

Potential targets and their relevant inhibitors in anti-influenza fields.

scientific article

Prolonged bioluminescence imaging in living cells and mice using novel pro-substrates for Renilla luciferase.

scientific article published on 27 November 2017

Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi.

scientific article published on 30 January 2008

QSAR studies of aminopeptidase N/CD13 (APN) inhibitors with the scaffold 3-phenylpropane-1,2-diamine and molecular docking

Quantitative kinetic investigation of triazole-gold(I) complex catalyzed [3,3]-rearrangement of propargyl ester

scientific article

Quenching the firefly bioluminescence by various ions

scientific article published on 20 January 2016

Quorum sensing inhibitors: a patent review

scientific article published on 19 March 2013

Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore

scientific article published on May 2008

Rational design, synthesis, biologic evaluation, and structure-activity relationship studies of novel 1-indanone alpha(1)-adrenoceptor antagonists

scientific article published on 10 October 2007

Real-Time Bioluminescence Imaging of Nitroreductase in Mouse Model

article

Recent advances in the boric acid/boronate-based fluorescent probes for detection of hydrogen peroxide

Recent progresses on AI-2 bacterial quorum sensing inhibitors

scientific article published on January 2012

Revisiting the homology modeling of G-protein coupled receptors: β1-adrenoceptor as an example

scientific article published on March 28, 2012

SecAAA trimer is fully functional as SecAA dimer in the membrane: existence of higher oligomers?

scientific article

Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety

scientific article

Self-organizing molecular field analysis on alpha(1a)-adrenoceptor dihydropyridine antagonists

scientific article published in September 2003

Small molecule inhibitors of histone acetyltransferase Tip60

scientific article

Store-operated CRAC channel inhibitors: opportunities and challenges

scientific article published on 5 May 2016

Strategies for atrial fibrillation therapy: focusing onIKurpotassium channel

Strategies in the design of small-molecule fluorescent probes for peptidases

scientific article published on 14 April 2014

Structure-Based Discovery and Experimental Verification of Novel AI-2 Quorum Sensing Inhibitors againstVibrio harveyi

scholarly article by Minyong Li et al published 18 August 2008 in ChemMedChem

Structure-Based Virtual Screening and Electrophysiological Evaluation of New Chemotypes of Kv1.5 Channel Blockers

Synthesis and activity evaluation of a new bestatin derivative LYP2 as an aminopeptidase N inhibitor

scientific article published on January 2011

Synthesis and biological evaluation of a series of aryl triazoles as firefly luciferase inhibitors

Synthesis and carbohydrate binding studies of fluorescent alpha-amidoboronic acids and the corresponding bisboronic acids

scientific article

Synthesis and characterization of N-2-aryl-1,2,3-triazole based iridium complexes as photocatalysts with tunable photoredox potential

scholarly article by Rong Cai et al published 2015 in Organic chemistry frontiers : an international journal of organic chemistry

Synthesis and characterization of bis-N-2-aryl triazole as a fluorophore

scientific article

Synthesis and evaluation of new antagonists of bacterial quorum sensing in Vibrio harveyi.

scientific article published in September 2009

Synthesis, evaluation, and computational studies of naphthalimide-based long-wavelength fluorescent boronic Acid reporters

scientific article published in January 2008

TET1-Mediated Oxidation of 5-Formylcytosine (5fC) to 5-Carboxycytosine (5caC) in RNA.

scientific article published on 2 November 2016

The effect of different electrostatic potentials on docking accuracy: A case study using DOCK5.4

scientific article published in 2008

The first low microM SecA inhibitors

scientific article

The first pharmacophore model for potent NF-kappaB inhibitors

scientific article published on 8 August 2009

The first ratiometric fluorescent probe for aminopeptidase N

article published in 2012

The first ratiometric fluorescent probes for aminopeptidase N cell imaging

scientific article published on November 23, 2012

The interactions between hERG potassium channel and blockers

scientific article published on January 2009

The medicinal chemistry of ion channels and their relevance in drug discovery

scientific article

The pharmacophore hypotheses of IKr potassium channel blockers: novel class III antiarrhythmic agents

scientific article published on 01 September 2004

Toward fluorescent probes for G-protein-coupled receptors (GPCRs).

scientific article published on 10 July 2014

Update on the slow delayed rectifier potassium current (I(Ks)): role in modulating cardiac function

scientific article published on January 2012

Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe

scientific article published on 01 April 2018

Visualization of α1-adrenergic receptors with phenylpiperazine-based fluorescent probes

scholarly article by Yuxing Lin et al published 21 March 2016 in Science China. Chemistry

cybLuc: An Effective Aminoluciferin Derivative for Deep Bioluminescence Imaging

scientific article published on 5 April 2017