List of works - Laurence Lins

"De novo" design of peptides with specific lipid-binding properties.

scientific article

1-Anilino-8-Naphtalene Sulfonate Probes a Gastric HK-ATPase Potassium Site Whose Access Requires Ionophores

scientific article published on 01 September 1998

A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains.

scientific article

Acylated and unacylated ghrelin binding to membranes and to ghrelin receptor: Towards a better understanding of the underlying mechanisms

scientific article published on 13 July 2010

Amphiphilic azobenzenes: Antibacterial activities and biophysical investigation of their interaction with bacterial membrane lipids

scientific article published on 28 October 2019

Analysis of accessible surface of residues in proteins

scientific article

Analysis of calcium-induced effects on the conformation of fengycin.

scientific article

Anti-hemostatic effects of a serpin from the saliva of the tick Ixodes ricinus

scientific article published on 3 May 2006

Apolipoprotein L-I is the trypanosome lytic factor of human serum

scientific article

Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes

scientific article

Are the fusion processes involved in birth, life and death of the cell depending on tilted insertion of peptides into membranes?

scientific article published on May 1999

Autosomal recessive segregation of a truncating mutation of anti-Müllerian type II receptor in a family affected by the persistent Müllerian duct syndrome contrasts with its dominant negative activity in vitro

scientific article

Beta-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: relevance to Alzheimer's disease

scientific article published in January 1999

C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

scientific article

Characterization of the interactions between fluoroquinolone antibiotics and lipids: a multitechnique approach.

scientific article published on 4 January 2008

Complementary biophysical tools to investigate lipid specificity in the interaction between bioactive molecules and the plasma membrane: A review

scientific article

Computational study of lipid-destabilizing protein fragments: Towards a comprehensive view of tilted peptides

scientific article published on 01 September 2001

Computational study of nisin interaction with model membrane.

scientific article

Conformational analysis of non-sulfonylurea hypoglycemic agents of the meglitinide family

scientific article published on 01 November 1995

Contributions and Limitations of Biophysical Approaches to Study of the Interactions between Amphiphilic Molecules and the Plant Plasma Membrane

scientific article published on 20 May 2020

Decrease of elastic moduli of DOPC bilayers induced by a macrolide antibiotic, azithromycin

scientific article published on 24 April 2007

Determination of the functionality of common APOA5 polymorphisms

scientific article published on 7 June 2005

Determination of the minimal fusion peptide of bovine leukemia virus gp30.

scientific article published on 8 February 2007

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

scientific article

Distribution of hydrophobic residues is crucial for the fusogenic properties of the Ebola virus GP2 fusion peptide.

scientific article published on February 2004

Domain Formation and Permeabilization Induced by the Saponin α-Hederin and Its Aglycone Hederagenin in a Cholesterol-Containing Bilayer

scientific article published on 14 April 2014

Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding

scientific article

Effects of surfactin on membrane models displaying lipid phase separation.

scientific article published on 14 November 2012

Enhancing the Membranolytic Activity of Chenopodium quinoa Saponins by Fast Microwave Hydrolysis

scientific article published on 09 April 2020

Enzymatic hydrolysis of reconstituted dimyristoylphosphatidylcholine-apo A-I complexes

scientific article published on 01 September 1993

Essential Oil-Based Bioherbicides: Human Health Risks Analysis

scientific article published on 30 August 2021

Eudicot plant-specific sphingolipids determine host selectivity of microbial NLP cytolysins.

scientific article

Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus

scientific article published on 29 April 2009

Fusogenic Tilted Peptides Induce Nanoscale Holes in Supported Phosphatidylcholine Bilayers

article

Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide

scientific article published in November 1996

Helix-helix interactions in reconstituted high-density lipoproteins

scientific article published on 01 August 1995

Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase.

scientific article published in January 2019

How different sterols contribute to saponin tolerant plasma membranes in sea cucumbers

scientific article published on 18 July 2018

Human recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties

scientific article published in July 2004

Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide

scientific article (publication date: 4 August 2000)

Impacts of the carbonyl group location of ester bond on interfacial properties of sugar-based surfactants: experimental and computational evidences.

scientific article

Importance of the hydrophobie energy: Structural determination of a hypoglycemie drug of the meglitinide family by nuclear magnetic resonance and molecular modeling

scientific article published on 01 October 1996

In silico predictions of 3D structures of linear and cyclic peptides with natural and non-proteinogenic residues

scientific article published on 27 October 2011

Insight into the Self-Assembling Properties of Peptergents: A Molecular Dynamics Simulation Study

scholarly article by Jean Marc Crowet published in September 2018

Insight into the Self-Assembling Properties of a Peptergent: A Molecular Dynamics Study

article published in 2018

Insights into the Relationships Between Herbicide Activities, Molecular Structure and Membrane Interaction of Cinnamon and Citronella Essential Oils Components

scientific article published on 16 August 2019

Insulinotropic action of (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinyl-carbonyl) propionate II. Ionophoretic and conformational aspects

scientific article published on 01 October 1995

Interaction network of antimicrobial peptides of Arabidopsis thaliana, based on high-throughput yeast two-hybrid screening

scientific article published on 14 July 2012

Interaction of Hexadecylbetainate Chloride with Biological Relevant Lipids

scientific article published on 07 February 2012

Interaction of the 106-126 prion peptide with lipid membranes and potential implication for neurotoxicity

scientific article

Interactions Between Natural Herbicides and Lipid Bilayers Mimicking the Plant Plasma Membrane

article

Interactions of ciprofloxacin with DPPC and DPPG: fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis

scientific article published on 6 September 2008

Interactions of sugar-based bolaamphiphiles with biomimetic systems of plasma membranes

scientific article

Ir-LBP, an ixodes ricinus tick salivary LTB4-binding lipocalin, interferes with host neutrophil function

scientific article

Is It Possible to Predict the Odor of a Molecule on the Basis of its Structure?

scientific article published on 20 June 2019

Is aggregation of β-amyloid peptides a mis-functioning of a current interaction process?

scientific article published on 01 April 2001

LCAT activation properties of apo A-I CNBr fragments and conversion of discoidal complexes into spherical particles

scientific article published on 01 October 1992

Linoleic and linolenic acid hydroperoxides interact differentially with biomimetic plant membranes in a lipid specific manner

scientific article published on 07 December 2018

Lipid-destabilising properties of a peptide with structural plasticity

scientific article published on 23 March 2006

Lipid-destabilizing properties of the hydrophobic helices H8 and H9 from colicin E1.

scientific article published in September 2007

Lipids or Proteins: Who Is Leading the Dance at Membrane Contact Sites?

scientific article published on 21 February 2019

Liquid crystalline phases induced by the hydroxyl group stereochemistry of amphiphilic carbohydrate bicatenary derivatives

scientific article

Mechanism of Trypanosoma brucei gambiense resistance to human serum

scientific article

Membrane Interactions of Natural Cyclic Lipodepsipeptides of the Viscosin Group.

scientific article published on 19 December 2016

Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus

scientific article published on 01 December 2002

Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo

scientific article published on 19 September 2012

Molecular determinants of the interaction between the C-terminal domain of Alzheimer's beta-amyloid peptide and apolipoprotein E alpha-helices

scientific article published in August 1999

Molecular dynamics study of micelles properties according to their size

scientific article

Molecular modeling of the amphipathic helices of the plasma apolipoproteins

scientific article published in July 1992

Monolayer properties of uronic acid bicatenary derivatives at the air–water interface: effect of hydroxyl group stereochemistry evidenced by experimental and computational approaches

scientific article published on 22 July 2011

Multi-scale simulation of the simian immunodeficiency virus fusion peptide.

scientific article published on 9 November 2012

Multiple C2 domains and transmembrane region proteins (MCTPs) tether membranes at plasmodesmata

scientific article published on 09 July 2019

Negatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY.

scientific article published on 04 May 2016

Neurotoxicity of the Putative Transmembrane Domain of the Prion Protein

scientific article published on 01 December 2000

PHARMACOLOGY OF THE HYPOGLYCAEMIC SULPHONYLUREA GLIQUIDONE III. CONFORMATIONAL ANALYSIS

scientific article published on 01 July 1996

Peptides in membranes: tipping the balance of membrane stability

scientific article published on May 1997

Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment.

scientific article published in January 2003

Plant-Pathogen Interactions: Underestimated Roles of Phyto-oxylipins

scientific article published on 23 October 2019

Plasma membrane localization of Solanum tuberosum remorin from group 1, homolog 3 is mediated by conformational changes in a novel C-terminal anchor and required for the restriction of potato virus X movement].

scientific article

Prolactin/growth hormone-derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis.

scholarly article

Rational design of complementary peptides to the betaAmyloid 29-42 fusion peptide: an application of PepDesign

scientific article published on 25 October 2005

Realistic modeling approaches of structure-function properties of CPPs in non-covalent complexes.

scientific article published on 23 February 2010

Relationships between the orientation and the structural properties of peptides and their membrane interactions.

scientific article published on 25 April 2008

Revisiting Plant Plasma Membrane Lipids in Tobacco: A Focus on Sphingolipids.

scientific article

SAHBNET, an accessible surface-based elastic network: an application to membrane protein.

scientific article published on 30 May 2013

Structural and functional properties of apolipoprotein B in chemically modified low density lipoproteins

scientific article published on December 1992

Structural basis for plant plasma membrane protein dynamics and organization into functional nanodomains

scientific article published on 31 July 2017

Structure of the apolipoprotein A-IV / lipid discoidal complexes: an attenuated total reflection polarized Fourier transform infrared spectroscopy study

article

Study of the specific lipid binding properties of Abeta 11-22 fragment at endosomal pH.

scientific article published in September 2009

Synthetic Rhamnolipid Bolaforms trigger an innate immune response in Arabidopsis thaliana.

scientific article published on 4 June 2018

Synthetic model peptides for apolipoproteins. I. Design and properties of synthetic model peptides for the amphipathic helices of the plasma apolipoproteins

article

Synthetic model peptides for apollpoproteins. II. Characterization of the discoidal complexes generated between phospholipids and synthetic model for apolipoproteins

article

The 118-135 peptide of the human prion protein forms amyloid fibrils and induces liposome fusion

scientific article published in December 1997

The CCK(-like) receptor in the animal kingdom: functions, evolution and structures

scientific article published on 15 December 2010

The N-terminal 12 residue long peptide of HIV gp41 is the minimal peptide sufficient to induce significant T-cell-like membrane destabilization in vitro

scientific article published on 25 April 2006

The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative?

scientific article published in February 2011

The SIV tilted peptide induces cylindrical reverse micelles in supported lipid bilayers

scientific article published in August 2006

The human VPAC1 receptor: three-dimensional model and mutagenesis of the N-terminal domain

scientific article

The minimal fusion peptide of simian immunodeficiency virus corresponds to the 11 first residues of gp32.

scientific article published in April 2008

Tilted peptides: a structural motif involved in protein membrane insertion?

scientific article published on 01 April 2008

Tilted properties of the 67-78 fragment of α-synuclein are responsible for membrane destabilization and neurotoxicity

scientific article published on 01 September 2007

Transferrin-binding protein B of Neisseria meningitidis: sequence-based identification of the transferrin-Binding site confirmed by site-directed mutagenesis

scientific article published on February 2004

List of works by Laurence Lins

"De novo" design of peptides with specific lipid-binding properties.

1-Anilino-8-Naphtalene Sulfonate Probes a Gastric HK-ATPase Potassium Site Whose Access Requires Ionophores

A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains.

Acylated and unacylated ghrelin binding to membranes and to ghrelin receptor: Towards a better understanding of the underlying mechanisms

Amphiphilic azobenzenes: Antibacterial activities and biophysical investigation of their interaction with bacterial membrane lipids

Analysis of accessible surface of residues in proteins

Analysis of calcium-induced effects on the conformation of fengycin.

Anti-hemostatic effects of a serpin from the saliva of the tick Ixodes ricinus

Apolipoprotein L-I is the trypanosome lytic factor of human serum

Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes

Are the fusion processes involved in birth, life and death of the cell depending on tilted insertion of peptides into membranes?

Autosomal recessive segregation of a truncating mutation of anti-Müllerian type II receptor in a family affected by the persistent Müllerian duct syndrome contrasts with its dominant negative activity in vitro

Beta-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: relevance to Alzheimer's disease

C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

Characterization of the interactions between fluoroquinolone antibiotics and lipids: a multitechnique approach.

Complementary biophysical tools to investigate lipid specificity in the interaction between bioactive molecules and the plasma membrane: A review

Computational study of lipid-destabilizing protein fragments: Towards a comprehensive view of tilted peptides

Computational study of nisin interaction with model membrane.

Conformational analysis of non-sulfonylurea hypoglycemic agents of the meglitinide family

Contributions and Limitations of Biophysical Approaches to Study of the Interactions between Amphiphilic Molecules and the Plant Plasma Membrane

Decrease of elastic moduli of DOPC bilayers induced by a macrolide antibiotic, azithromycin

Determination of the functionality of common APOA5 polymorphisms

Determination of the minimal fusion peptide of bovine leukemia virus gp30.

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

Distribution of hydrophobic residues is crucial for the fusogenic properties of the Ebola virus GP2 fusion peptide.

Domain Formation and Permeabilization Induced by the Saponin α-Hederin and Its Aglycone Hederagenin in a Cholesterol-Containing Bilayer

Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding

Effects of surfactin on membrane models displaying lipid phase separation.

Enhancing the Membranolytic Activity of Chenopodium quinoa Saponins by Fast Microwave Hydrolysis

Enzymatic hydrolysis of reconstituted dimyristoylphosphatidylcholine-apo A-I complexes

Essential Oil-Based Bioherbicides: Human Health Risks Analysis

Eudicot plant-specific sphingolipids determine host selectivity of microbial NLP cytolysins.

Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus

Fusogenic Tilted Peptides Induce Nanoscale Holes in Supported Phosphatidylcholine Bilayers

Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide

Helix-helix interactions in reconstituted high-density lipoproteins

Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase.

How different sterols contribute to saponin tolerant plasma membranes in sea cucumbers

Human recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties

Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide

Impacts of the carbonyl group location of ester bond on interfacial properties of sugar-based surfactants: experimental and computational evidences.

Importance of the hydrophobie energy: Structural determination of a hypoglycemie drug of the meglitinide family by nuclear magnetic resonance and molecular modeling

In silico predictions of 3D structures of linear and cyclic peptides with natural and non-proteinogenic residues

Insight into the Self-Assembling Properties of Peptergents: A Molecular Dynamics Simulation Study

Insight into the Self-Assembling Properties of a Peptergent: A Molecular Dynamics Study

Insights into the Relationships Between Herbicide Activities, Molecular Structure and Membrane Interaction of Cinnamon and Citronella Essential Oils Components

Insulinotropic action of (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinyl-carbonyl) propionate II. Ionophoretic and conformational aspects

Interaction network of antimicrobial peptides of Arabidopsis thaliana, based on high-throughput yeast two-hybrid screening

Interaction of Hexadecylbetainate Chloride with Biological Relevant Lipids

Interaction of the 106-126 prion peptide with lipid membranes and potential implication for neurotoxicity

Interactions Between Natural Herbicides and Lipid Bilayers Mimicking the Plant Plasma Membrane

Interactions of ciprofloxacin with DPPC and DPPG: fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis

Interactions of sugar-based bolaamphiphiles with biomimetic systems of plasma membranes

Ir-LBP, an ixodes ricinus tick salivary LTB4-binding lipocalin, interferes with host neutrophil function

Is It Possible to Predict the Odor of a Molecule on the Basis of its Structure?

Is aggregation of β-amyloid peptides a mis-functioning of a current interaction process?

LCAT activation properties of apo A-I CNBr fragments and conversion of discoidal complexes into spherical particles

Linoleic and linolenic acid hydroperoxides interact differentially with biomimetic plant membranes in a lipid specific manner

Lipid-destabilising properties of a peptide with structural plasticity

Lipid-destabilizing properties of the hydrophobic helices H8 and H9 from colicin E1.

Lipids or Proteins: Who Is Leading the Dance at Membrane Contact Sites?

Liquid crystalline phases induced by the hydroxyl group stereochemistry of amphiphilic carbohydrate bicatenary derivatives

Mechanism of Trypanosoma brucei gambiense resistance to human serum

Membrane Interactions of Natural Cyclic Lipodepsipeptides of the Viscosin Group.

Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus

Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo

Molecular determinants of the interaction between the C-terminal domain of Alzheimer's beta-amyloid peptide and apolipoprotein E alpha-helices

Molecular dynamics study of micelles properties according to their size

Molecular modeling of the amphipathic helices of the plasma apolipoproteins

Monolayer properties of uronic acid bicatenary derivatives at the air–water interface: effect of hydroxyl group stereochemistry evidenced by experimental and computational approaches

Multi-scale simulation of the simian immunodeficiency virus fusion peptide.

Multiple C2 domains and transmembrane region proteins (MCTPs) tether membranes at plasmodesmata

Negatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY.

Neurotoxicity of the Putative Transmembrane Domain of the Prion Protein

PHARMACOLOGY OF THE HYPOGLYCAEMIC SULPHONYLUREA GLIQUIDONE III. CONFORMATIONAL ANALYSIS

Peptides in membranes: tipping the balance of membrane stability

Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment.

Plant-Pathogen Interactions: Underestimated Roles of Phyto-oxylipins

Plasma membrane localization of Solanum tuberosum remorin from group 1, homolog 3 is mediated by conformational changes in a novel C-terminal anchor and required for the restriction of potato virus X movement].