List of works - Sacha Jensen

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

scientific article

A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion

scientific article published on 22 October 2019

A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasias

scientific article published on 15 May 2015

Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern

scientific article published on 28 October 2019

Biophysical characterisation of fibulin-5 proteins associated with disease

scientific article

C-terminal propeptide is required for fibrillin-1 secretion and blocks premature assembly through linkage to domains cbEGF41-43.

scientific article

Ca2+-dependent interface formation in fibrillin-1.

scientific article

Dissecting the fibrillin microfibril: structural insights into organization and function

scientific article published on February 2012

Hydrophobic Domains of Human Tropoelastin Interact in a Context-dependent Manner

scientific article published on 19 September 2001

Juvenile idiopathic arthritis, mitral valve prolapse and a familial variant involving the integrin-binding fragment of FBN1

scientific article published on 21 June 2013

Mutations in the TGFβ binding-protein-like domain 5 of FBN1 are responsible for acromicric and geleophysic dysplasias

scientific article

New insights into the structure, assembly and biological roles of 10-12 nm connective tissue microfibrils from fibrillin-1 studies

scientific article published on April 2016

Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1

scientific article (publication date: 26 October 2001)

Rational design of tropoelastin peptide-based inhibitors of metalloproteinases

scientific article

Structural changes and facilitated association of tropoelastin

scientific article

Structural consequences of cysteine substitutions C1977Y and C1977R in calcium-binding epidermal growth factor-like domain 30 of human fibrillin-1.

scientific article published on 14 September 2004

Structure and interdomain interactions of a hybrid domain: a disulphide-rich module of the fibrillin/LTBP superfamily of matrix proteins

scientific article

Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly

scientific article

TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs

scientific article published on January 2011

The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.

scientific article published on 21 June 2017

¹H, ¹³C and ¹⁵N assignments of the four N-terminal domains of human fibrillin-1.

scientific article

¹H, ¹³C and ¹⁵N resonance assignments for the fibrillin-1 EGF2-EGF3-hybrid1-cbEGF1 four-domain fragment

scientific article

List of works by Sacha Jensen

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion

A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasias

Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern

Biophysical characterisation of fibulin-5 proteins associated with disease

C-terminal propeptide is required for fibrillin-1 secretion and blocks premature assembly through linkage to domains cbEGF41-43.

Ca2+-dependent interface formation in fibrillin-1.

Dissecting the fibrillin microfibril: structural insights into organization and function

Hydrophobic Domains of Human Tropoelastin Interact in a Context-dependent Manner

Juvenile idiopathic arthritis, mitral valve prolapse and a familial variant involving the integrin-binding fragment of FBN1

Mutations in the TGFβ binding-protein-like domain 5 of FBN1 are responsible for acromicric and geleophysic dysplasias

New insights into the structure, assembly and biological roles of 10-12 nm connective tissue microfibrils from fibrillin-1 studies

Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1

Rational design of tropoelastin peptide-based inhibitors of metalloproteinases

Structural changes and facilitated association of tropoelastin

Structural consequences of cysteine substitutions C1977Y and C1977R in calcium-binding epidermal growth factor-like domain 30 of human fibrillin-1.

Structure and interdomain interactions of a hybrid domain: a disulphide-rich module of the fibrillin/LTBP superfamily of matrix proteins

Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly

TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs

The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.

¹H, ¹³C and ¹⁵N assignments of the four N-terminal domains of human fibrillin-1.

¹H, ¹³C and ¹⁵N resonance assignments for the fibrillin-1 EGF2-EGF3-hybrid1-cbEGF1 four-domain fragment