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List of works by Diego Pasini

A model for transmission of the H3K27me3 epigenetic mark

scientific article published on 19 October 2008

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

scientific article published on July 2004

Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus

scientific article

Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer.

scientific article

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

scientific article

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells

scientific article

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype

scientific article published on 01 August 2020

Control of adult intestinal identity by the Polycomb repressive machinery

scientific article published on 15 November 2016

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

scientific article

Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

scientific article

Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity

scientific article published on 11 April 2019

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

scientific article

Emerging roles for Polycomb proteins in cancer

scientific article published on 2 May 2016

EpiMINE, a computational program for mining epigenomic data

scientific article

Epigenetic factors in cancer development: polycomb group proteins

scientific article published on January 2011

Epigenetic methylations and their connections with metabolism.

scientific article published on March 2013

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

scientific article published on 29 May 2017

Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.

scientific article

Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities

scientific article published on 24 April 2019

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

scientific article (publication date: May 2006)

Identification of a choroid plexus vascular barrier closing during intestinal inflammation

Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

scientific article published on 30 August 2018

Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions

scientific article published on 9 May 2014

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

scientific article

Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type-dependent outcomes

scientific article published on 15 May 2019

Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.

scientific article published on 7 October 2016

Mapping the Function of Polycomb Proteins

scientific article published in January 2016

NPAT expression is regulated by E2F and is essential for cell cycle progression

scientific article

PRC2 preserves intestinal progenitors and restricts secretory lineage commitment.

scientific article

Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.

scientific article published on 28 October 2015

Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.

scientific article published on 2 June 2008

Polycomb complexes act redundantly to repress genomic repeats and genes

scientific article

Polycomb group proteins in cell cycle progression and cancer.

scientific article published in April 2004

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

scientific article published on 14 April 2014

Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity

scientific article

Precision mapping of coexisting modifications in histone H3 tails from embryonic stem cells by ETD-MS/MS.

scientific article published on 16 August 2013

Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36

scientific article

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3

scientific article

Regulation and function of DNA and histone methylations

scientific article published on January 2013

Regulation of stem cell differentiation by histone methyltransferases and demethylases

scientific article

Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

scientific article

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

scientific article

Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells

scientific article

The Dual Role of EPOP and Elongin BC in Controlling Transcriptional Activity

scientific article published in November 2016

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells

scientific article published on 22 March 2018

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

scientific article

The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?

scientific article

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

scientific article published on 5 March 2007

The polycomb repressive complex 2 is a potential target of SUMO modifications

scientific article

Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development

scientific article published on 23 May 2016

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

scientific article (publication date: 11 October 2007)

VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression

scientific article published on 12 December 2017

Yin Yang 1 extends the Myc-related transcription factors network in embryonic stem cells.

scientific article published on 30 December 2011

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