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List of works by Nigel C. Jones

A genetic epilepsy rat model displays endophenotypes of psychosis

scientific article published on 11 February 2010

A mouse model of Alzheimer's disease displays increased susceptibility to kindling and seizure-associated death

scientific article published on 16 April 2015

A rat model of valproate teratogenicity from chronic oral treatment during pregnancy

scientific article published on 16 May 2020

A regulatory role for protease-activated receptor-2 in motivational learning in rats.

scientific article published on 4 May 2009

Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice

scientific article

Acute administration of typical and atypical antipsychotics reduces EEG γ power, but only the preclinical compound LY379268 reduces the ketamine-induced rise in γ power

scientific article

Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy

scientific article published on 27 July 2018

Antagonism of the interleukin-1 receptor following traumatic brain injury in the mouse reduces the number of nitric oxide synthase-2-positive cells and improves anatomical and functional outcomes

scientific article published on 01 July 2005

Antidepressant therapy in epilepsy: can treating the comorbidities affect the underlying disorder?

scientific article published on April 1, 2013

Anxiolytic effects of rapid amygdala kindling, and the influence of early life experience in rats

scientific article published on 3 May 2009

Axon initial segment structural plasticity in animal models of genetic and acquired epilepsy

scientific article published on 17 April 2013

Brain-derived neurotrophic factor haploinsufficiency impairs high-frequency cortical oscillations in mice

scientific article

Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?

scientific article

Chronic administration of antipsychotics attenuates ongoing and ketamine-induced increases in cortical γ oscillations

scientific article published on 25 June 2014

Chronic antidepressant treatment accelerates kindling epileptogenesis in rats

scientific article

Chronic fluoxetine treatment accelerates kindling epileptogenesis in mice independently of 5-HT2A receptors

scientific article published on 01 June 2018

Cognitive deficits in a rat model of temporal lobe epilepsy using touchscreen-based translational tools

scientific article published on 23 July 2019

Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation

scientific article published on 25 April 2011

Confounding neurodegenerative effects of manganese for in vivo MR imaging in rat models of brain insults

scientific article published on 18 July 2011

DNA methylation mediates persistent epileptiform activity in vitro and in vivo

scientific article (publication date: 2013)

Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype

scientific article published on 11 July 2016

Disease-Modification in Epilepsy by Nonpharmacological Methods.

scientific article published in January 2018

Disease-Modifying Effects of Neural Regeneration Peptide 2945 in the GAERS Model of Absence Epilepsy

scientific article published on 16 May 2017

Early life maternal separation stress augmentation of limbic epileptogenesis: the role of corticosterone and HPA axis programming

scientific article published on 21 January 2014

Early life stress as an influence on limbic epilepsy: an hypothesis whose time has come?

scientific article published on 05 October 2009

Early life stress enhancement of limbic epileptogenesis in adult rats: mechanistic insights

scientific article

Early postnatal stress confers enduring vulnerability to limbic epileptogenesis

scientific article published in November 2007

Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes

scientific article published on 29 October 2009

Effects of aberrant gamma frequency oscillations on prepulse inhibition

scientific article published on 15 May 2014

Electrophysiological insights into the enduring effects of early life stress on the brain

scientific article published on 17 December 2010

Elevated anxiety and depressive-like behavior in a rat model of genetic generalized epilepsy suggesting common causation

scientific article published on 5 October 2007

Enduring Effects of Early Life Stress on Firing Patterns of Hippocampal and Thalamocortical Neurons in Rats: Implications for Limbic Epilepsy

scientific article

Environmental enrichment delays limbic epileptogenesis and restricts pathologic synaptic plasticity

scientific article published on 20 January 2016

Environmental enrichment imparts disease-modifying and transgenerational effects on genetically-determined epilepsy and anxiety

scientific article published on 13 May 2016

Estradiol and raloxifene modulate hippocampal gamma oscillations during a spatial memory task

scientific article

Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy

scientific article published on 6 March 2013

Evaluating whole genome sequence data from the Genetic Absence Epilepsy Rat from Strasbourg and its related non-epileptic strain.

scientific article published on 14 July 2017

Experimental traumatic brain injury induces a pervasive hyperanxious phenotype in rats

scientific article

Extensive phenotyping of two ARX polyalanine expansion mutation mouse models that span clinical spectrum of intellectual disability and epilepsy

scientific article published on 07 June 2017

Granulocyte-macrophage colony-stimulating factor is neuroprotective in experimental traumatic brain injury

scientific article

HCN channelopathy and cardiac electrophysiologic dysfunction in genetic and acquired rat epilepsy models

Hyperphosphorylated tau is implicated in acquired epilepsy and neuropsychiatric comorbidities

scientific article published on 10 December 2013

Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE.

scientific article published on 12 June 2012

Imaging biomarkers of posttraumatic epileptogenesis

scientific article published on 08 October 2019

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

scientific article published on 12 July 2011

Interaction between sex and early-life stress: influence on epileptogenesis and epilepsy comorbidities

scientific article published on 28 September 2014

Isoflurane induces cognitive deficits in the Morris water maze task in rats

scientific article published in May 2012

Local NMDA receptor hypofunction evokes generalized effects on gamma and high-frequency oscillations and behavior

scientific article

Memory impairment in rats after desflurane anesthesia is age and dose dependent

scientific article published in January 2015

Microglial polarization in posttraumatic epilepsy: Potential mechanism and treatment opportunity

scientific article published on 13 January 2020

Morphometric abnormalities and hyperanxiety in genetically epileptic rats: a model of psychiatric comorbidity?

scientific article published on 25 December 2008

Morphometric changes and molecular mechanisms in rat models of idiopathic generalized epilepsy with absence seizures

scientific article published on February 24, 2011

Mutations of the Sonic Hedgehog Pathway Underlie Hypothalamic Hamartoma with Gelastic Epilepsy

scientific article published on 20 July 2016

NMDA receptor hypofunction leads to generalized and persistent aberrant gamma oscillations independent of hyperlocomotion and the state of consciousness

scientific article

Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse

scientific article published on 19 May 2015

Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status

scientific article published on 04 March 2016

Neuropsychiatric symptomatology predicts seizure recurrence in newly treated patients

scientific article published in September 2010

Potential Roles for the GluN2D NMDA Receptor Subunit in Schizophrenia

scientific article published in 2023

Potentiating the Strength of Extrasynaptic Currents by Neurosteroid Hormones

scientific article published on July 2016

Progressive metabolic and structural cerebral perturbations after traumatic brain injury: an in vivo imaging study in the rat.

scientific article published on November 2010

Repeatedly stressed rats have enhanced vulnerability to amygdala kindling epileptogenesis

scientific article published on 29 June 2012

Reply to: Isoflurane is not necessarily the only cause of cognitive deficits

scientific article published in January 2013

Reversal of evoked gamma oscillation deficits is predictive of antipsychotic activity with a unique profile for clozapine.

scientific article

Seizure expression, behavior, and brain morphology differences in colonies of Genetic Absence Epilepsy Rats from Strasbourg

scientific article published on 6 November 2014

Sensitive quantitative detection of somatic mosaic mutation in "double cortex" syndrome

scientific article published on 20 December 2017

Sevoflurane anesthesia does not impair acquisition learning or memory in the Morris water maze in young adult and aged rats

scientific article published in November 2012

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

scientific article published on 13 March 2015

Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.

scientific article published on 11 June 2016

Stress, epilepsy, and psychiatric comorbidity: How can animal models inform the clinic?

scientific article published on October 23, 2012

T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures

scientific article published on February 2012

Targeting Glioma Stem Cells by Functional Inhibition of Dynamin 2: A Novel Treatment Strategy for Glioblastoma

scientific article published on 25 March 2019

Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models

scientific article

Targeting neurodegeneration to prevent post-traumatic epilepsy

scientific article published on 09 August 2018

The N-Methyl d-Aspartate Glutamate Receptor Antagonist Ketamine Disrupts the Functional State of the Corticothalamic Pathway.

scientific article published on 3 June 2016

The acceleration of amygdala kindling epileptogenesis by chronic low-dose corticosterone involves both mineralocorticoid and glucocorticoid receptors

scientific article

The effect of amygdala kindling on neuronal firing patterns in the lateral thalamus in the GAERS model of absence epilepsy

scientific article published on 27 March 2014

The genetic ablation of tau improves long-term, but not short-term, functional outcomes after experimental traumatic brain injury in mice

scientific article published on 16 September 2019

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states

scientific article

The mGluR2/3 agonist LY379268 reverses NMDA receptor antagonist effects on cortical gamma oscillations and phase coherence, but not working memory impairments, in mice

scientific article published on 03 October 2019

The neuroprotective effect of progesterone after traumatic brain injury in male mice is independent of both the inflammatory response and growth factor expression

scientific article

Tissue plasminogen activator does not alter development of acquired epilepsy

scientific article published on 7 September 2012

Unravelling the Role of Glycogen Synthase Kinase-3 in Alzheimer's Disease-Related Epileptic Seizures

scientific article published on 23 May 2020