List of works - Takeshi Noda

A protein conjugation system essential for autophagy

scientific article

A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes

scientific article

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

scientific article

A ubiquitin-like system mediates protein lipidation

scientific article

An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure

scientific article

An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7

scientific article

Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae

scientific article

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

scientific article

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

scientific article

Apg2p functions in autophagosome formation on the perivacuolar structure

scientific article

Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways

scientific article

Atg14L recruits PtdIns 3-kinase to the ER for autophagosome formation

scientific article published in April 2011

Atg4B(C74A) hampers autophagosome closure: a useful protein for inhibiting autophagy

scientific article

Atg9A trafficking through the recycling endosomes is required for autophagosome formation.

scientific article published in September 2016

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

scientific article

Author Correction: STEEP mediates STING ER exit and activation of signaling

scientific article published on 14 September 2020

Autophagosome formation in relation to the endoplasmic reticulum

scientific article published on 22 October 2020

Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion

scientific article

Autophagosomes form at ER-mitochondria contact sites

scientific article

Autophagy in the context of the cellular membrane-trafficking system: the enigma of Atg9 vesicles

scientific article published on 17 November 2017

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

scientific article (publication date: October 1992)

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

scientific article

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

scientific article

Between canonical and antibacterial autophagy: Rab7 is required for GAS-containing autophagosome-like vacuole formation

scientific article published on 08 April 2010

Binding Rubicon to cross the Rubicon.

scientific article

Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy

scientific article published on 01 January 2008

Chemical modulators of autophagy as biological probes and potential therapeutics

scientific article published on January 2011

Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes

scientific article published on 20 January 2010

Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole

scientific article

Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts

scientific article published on 25 September 2009

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

scientific article (publication date: 2007)

Dynamic relocation of the TORC1-Gtr1/2-Ego1/2/3 complex is regulated by Gtr1 and Gtr2.

scientific article

Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes

scientific article

Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus

scientific article published on 12 October 2011

ERdj8 governs the size of autophagosomes during the formation process

scientific article published on 01 August 2020

Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation

scientific article

Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes.

scientific article

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

scientific article

Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy

scientific article published on 01 October 2019

Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane.

scientific article published on 26 April 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

scientific article

Induction of selective autophagy in cells replicating hepatitis C virus genome

scientific article published on 12 October 2018

Interrelationships among Atg proteins during autophagy inSaccharomyces cerevisiae

scientific article published in 2004

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

scientific article

Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene

scientific article

Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy

scientific article

Molecular basis of canonical and bactericidal autophagy

scientific article published on 07 September 2009

Monitoring autophagy in mammalian cultured cells through the dynamics of LC3.

scientific article published in January 2009

Morphological analysis of autophagy

scientific article

Mutational analysis of Csc1/Vps4p: involvement of endosome in regulation of autophagy in yeast

scientific article

Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells

scientific article published on 11 February 2020

Ole1, fatty acid desaturase, is required for Atg9 delivery and isolation membrane expansion during autophagy in Saccharomyces cerevisiae

scientific article published on 23 November 2016

Osteoblastic lysosome plays a central role in mineralization

scientific article published on 03 July 2019

Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain

scientific article

Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation

scientific article published on 19 September 2013

Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy

scientific article published on 19 October 2004

Quantitative Assay of Macroautophagy Using Pho8△60 Assay and GFP-Cleavage Assay in Yeast

scientific article published on 22 November 2016

Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy

scientific article

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

scientific article published on 07 October 2013

Regulation of Autophagy through TORC1 and mTORC1.

scientific article

Regulation of membrane biogenesis in autophagy via PI3P dynamics

scientific article published on 18 April 2010

Rheb localized on the Golgi membrane activates lysosome-localized mTORC1 at the Golgi-lysosome contact site.

scientific article

Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain

scientific article published on 13 October 2010

STEEP mediates STING ER exit and activation of signaling

scientific article published on 20 July 2020

Starvation triggers the delivery of the endoplasmic reticulum to the vacuole via autophagy in yeast

scientific article published in January 2005

Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan

scientific article published on 05 March 2020

Study on Autophagy by Professor Ohsumi: Nobel Prize Originated from the Frontier

TRAPPIII is responsible for vesicular transport from early endosomes to Golgi, facilitating Atg9 cycling in autophagy

scientific article

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

scientific article

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

scientific article

The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity

scientific journal article

The Ubi brothers reunited

scientific article

The early secretory pathway contributes to autophagy in yeast

scientific article published in February 2003

The late stages of autophagy: how does the end begin?

scientific article published on 08 May 2009

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

scientific article

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

scientific article

Three-Axis Model for Atg Recruitment in Autophagy against Salmonella

scientific article published on 28 February 2012

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

scientific article

Toward unraveling membrane biogenesis in mammalian autophagy

scientific article published on 28 May 2008

Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae

article published in 2008

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

scientific article

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

scientific article

Vacuole-mediated selective regulation of TORC1-Sch9 signaling following oxidative stress

scientific article

Viability assays to monitor yeast autophagy

scientific article published in January 2008

Yeast autophagosomes: de novo formation of a membrane structure

scientific article

[Endosomal sorting system regulated by ubiquitin]

scientific article published on 01 August 2006

[Molecular mechanism of autophagosome formation in mammalian cells].

scientific article

List of works by Takeshi Noda

A protein conjugation system essential for autophagy

A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

A ubiquitin-like system mediates protein lipidation

An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure

An initial step of GAS-containing autophagosome-like vacuoles formation requires Rab7

Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

Apg2p functions in autophagosome formation on the perivacuolar structure

Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways

Atg14L recruits PtdIns 3-kinase to the ER for autophagosome formation

Atg4B(C74A) hampers autophagosome closure: a useful protein for inhibiting autophagy

Atg9A trafficking through the recycling endosomes is required for autophagosome formation.

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

Author Correction: STEEP mediates STING ER exit and activation of signaling

Autophagosome formation in relation to the endoplasmic reticulum

Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion

Autophagosomes form at ER-mitochondria contact sites

Autophagy in the context of the cellular membrane-trafficking system: the enigma of Atg9 vesicles

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Between canonical and antibacterial autophagy: Rab7 is required for GAS-containing autophagosome-like vacuole formation

Binding Rubicon to cross the Rubicon.

Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy

Chemical modulators of autophagy as biological probes and potential therapeutics

Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes

Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole

Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

Dynamic relocation of the TORC1-Gtr1/2-Ego1/2/3 complex is regulated by Gtr1 and Gtr2.

Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes

Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus

ERdj8 governs the size of autophagosomes during the formation process

Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation

Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes.

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy

Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane.

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

Induction of selective autophagy in cells replicating hepatitis C virus genome

Interrelationships among Atg proteins during autophagy inSaccharomyces cerevisiae

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene

Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy

Molecular basis of canonical and bactericidal autophagy

Monitoring autophagy in mammalian cultured cells through the dynamics of LC3.

Morphological analysis of autophagy

Mutational analysis of Csc1/Vps4p: involvement of endosome in regulation of autophagy in yeast

Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells

Ole1, fatty acid desaturase, is required for Atg9 delivery and isolation membrane expansion during autophagy in Saccharomyces cerevisiae

Osteoblastic lysosome plays a central role in mineralization

Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain

Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation

Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy

Quantitative Assay of Macroautophagy Using Pho8△60 Assay and GFP-Cleavage Assay in Yeast

Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

Regulation of Autophagy through TORC1 and mTORC1.

Regulation of membrane biogenesis in autophagy via PI3P dynamics

Rheb localized on the Golgi membrane activates lysosome-localized mTORC1 at the Golgi-lysosome contact site.

Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain

STEEP mediates STING ER exit and activation of signaling

Starvation triggers the delivery of the endoplasmic reticulum to the vacuole via autophagy in yeast

Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan

Study on Autophagy by Professor Ohsumi: Nobel Prize Originated from the Frontier

TRAPPIII is responsible for vesicular transport from early endosomes to Golgi, facilitating Atg9 cycling in autophagy

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity

The Ubi brothers reunited

The early secretory pathway contributes to autophagy in yeast

The late stages of autophagy: how does the end begin?

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway