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List of works by David B. Sacks

2011 consensus meeting on the worldwide standardization of hemoglobin A(1c) measurement

scientific article published in May 2013

A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions

scientific article

A1C Combined With Glycated Albumin Improves Detection of Prediabetes in Africans: The Africans in America Study.

scientific article published on 17 December 2015

A1C Versus Glucose Testing: A Comparison ⬇️

scientific article published on February 1, 2011

AKAP220 protein organizes signaling elements that impact cell migration.

scientific article published on 2 September 2011

Absence of IQGAP1 Protein Leads to Insulin Resistance

scientific article published on 12 January 2017

Actin pedestal formation by enteropathogenic Escherichia coli is regulated by IQGAP1, calcium, and calmodulin

scientific article published on 22 September 2008

Acute coronary ischemia: troponin I and T.

scientific article

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.

scientific article published on 21 November 2016

Alteration of calmodulin-protein interactions by a monoclonal antibody to calmodulin

scientific article published on 01 May 1994

Amylin--a glucoregulatory hormone involved in the pathogenesis of diabetes mellitus?

scientific article published on 01 April 1996

Analysis of phosphorylation and mutation of tyrosine residues of calmodulin on its activation of the erythrocyte Ca(2+)-transporting ATPase

scientific article published on 01 July 1996

Assessment of the interaction between calmodulin and casein kinase II

scientific article published on 01 September 1994

Association of Sickle Cell Trait With Hemoglobin A1c in African Americans

scientific article

Binding of IRS proteins to calmodulin is enhanced in insulin resistance

scientific article published on 01 May 2000

Ca2+ regulates calmodulin binding to IQ motifs in IRS-1

scientific article published on 01 December 1996

Ca2+-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1

scientific article published on 26 November 2019

Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α

scientific article published on 08 August 2018

Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α.

scientific article

Calmodulin activates phosphatidylinositol 3-kinase

scientific article

Calmodulin activates the Hippo signaling pathway by promoting LATS1 kinase-mediated inhibitory phosphorylation of the transcriptional coactivator YAP

scientific article published on 17 March 2022

Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes

scientific article published on February 2000

Calmodulin as substrate for insulin-receptor kinase. Phosphorylation by receptors from rat skeletal muscle

scientific article published on 01 January 1989

Calmodulin binds HER2 and modulates HER2 signaling

scientific article

Calmodulin binds to p21(Cip1) and is involved in the regulation of its nuclear localization

scientific article published on August 1999

Calmodulin enhances the stability of the estrogen receptor

scientific article published on 15 February 2001

Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

scientific article (publication date: 13 June 1997)

Calmodulin phosphorylation and modulation of endothelial nitric oxide synthase catalysis.

scholarly article

Calmodulin regulates the transcriptional activity of estrogen receptors. Selective inhibition of calmodulin function in subcellular compartments

scientific article

Calmodulin-specific monoclonal antibodies inhibit DNA replication in mammalian cells

scientific article published on November 3, 1992

Casein kinase II-catalysed phosphorylation of calmodulin is altered by amino acid deletions in the central helix of calmodulin.

scientific article published in October 1992

Commentary

Comparing analytic performance criteria: evaluation of HbA1c certification criteria as an example

scientific article

Comparing multiple measures of glycemia: how to transition from biomarker to diagnostic test?

scientific article published on 31 October 2012

Compartmentalised MAPK pathways.

scientific article published on January 2008

Continuous Glucose Monitors and Automated Insulin Dosing Systems in the Hospital Consensus Guideline

scientific article published on 28 September 2020

Current status of US programs for training clinical laboratory scientists and anticipated impact of healthcare reform

scientific article published on 01 June 1995

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex ⬇️

scientific article published on June 27, 2011

Detection of abnormal glucose tolerance in Africans is improved by combining A1C with fasting glucose: the Africans in America Study

scientific article

Detection of unsuspected myocardial necrosis by rapid bedside assay for cardiac troponin T

scientific article published on 01 May 1997

Detrimental Effects of Not Using International Reference Materials to Calibrate Cystatin C Assays

scientific article published on 9 November 2015

Diabetes: advances and controversies

scientific article published on 13 December 2010

Diagnosis of gestational diabetes mellitus: it is time for international consensus

scientific article published on 23 September 2013

Differential affinity cross-linking of phosphorylase kinase conformers by the geometric isomers of phenylenedimaleimide

scientific article published on 01 October 1997

Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells

scientific article

E-cadherin-mediated cell-cell attachment activates Cdc42

scientific article published on 01 November 2000

E6AP and calmodulin reciprocally regulate estrogen receptor stability.

scientific article published on 28 November 2005

Effects of cationic polypeptides on the activity, substrate interaction, and autophosphorylation of casein kinase II: a study with calmodulin

scientific article published on 01 December 1992

Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin.

scientific article

Elevation of troponin I levels in patients without evidence of myocardial injury

scientific article published on 01 December 1997

Emergency department triage strategies for acute chest pain using creatine kinase-MB and troponin I assays: a cost-effectiveness analysis

scientific article published on 01 December 1999

Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras

scientific article published on 30 July 2019

Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

scientific article published on 08 August 2019

Evaluation of a rapid bedside assay for detection of serum cardiac troponin T

scientific article published on 01 April 1995

Evaluation of hemoglobin A1c measurement by Capillarys 2 electrophoresis for detection of abnormal glucose tolerance in African immigrants to the United States.

scientific article published on 8 April 2015

Executive summary. The National Academy of Clinical Biochemistry Laboratory Medicine Practice Guideline: evidence-based practice for point-of-care testing

scientific article published on 12 January 2007

Executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

scientific article published on 26 May 2011

Functional interactions between calmodulin and estrogen receptor-alpha.

scientific article published on 27 October 2006

Gaps in the Glycation Gap Hypothesis

scientific article published on 02 December 2010

Gestational Diabetes Mellitus: Why the Controversy?

scientific article published on 11 October 2017

Global harmonization of hemoglobin A1c

scientific article published on 01 April 2005

Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group

scientific article published in January 2007

Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring

scientific article published on 17 September 2018

Glycated Albumin Identifies Prediabetes Not Detected by Hemoglobin A1c: The Africans in America Study

scientific article published on 13 September 2016

Glycated protein update: implications of recent studies, including the diabetes control and complications trial.

scientific article published on May 1994

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

scientific article

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

scientific article published on 01 March 2002

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

scientific article published on 26 May 2011

Haemoglobin A1c analysis in the management of patients with diabetes: from chaos to harmony.

scientific article published on September 2008

Halothane hepatitis

scientific article published on 01 May 1986

HbA1c: what do the numbers really mean? ⬇️

scientific article published on September 17, 2011

Hemoglobin A1c and Race: Should Therapeutic Targets and Diagnostic Cutoffs Differ among Racial Groups?

scientific article published on 07 July 2016

Hemoglobin A1c in diabetes: panacea or pointless?

scientific article

Hemoglobin variants and hemoglobin A1c analysis: problem solved?

scientific article (publication date: August 2003)

Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier

scientific article

Higher degree of glycation of hemoglobin S compared to hemoglobin A measured by mass spectrometry: Potential impact on HbA1c testing.

scientific article published on 22 April 2016

Hypophosphataemia in acute pancreatitis

scientific article published on 01 July 1985

IQGAP proteins are integral components of cytoskeletal regulation

scientific article

IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity

scientific article published on 20 July 2016

IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma

scientific article

IQGAP1 and calmodulin modulate E-cadherin function

scientific article (publication date: 31 December 1999)

IQGAP1 and its binding proteins control diverse biological functions ⬇️

scientific article published on December 11, 2011

IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton ⬇️

scientific article published on May 8, 2003

IQGAP1 binds AMPK and is required for maximum AMPK activation

scientific article published on 15 November 2020

IQGAP1 binds Rap1 and modulates its activity

scientific article published on 21 May 2007

IQGAP1 binds the Axl receptor kinase and inhibits its signaling

scientific article published on 09 October 2018

IQGAP1 binds to estrogen receptor-α and modulates its function

scientific article published on 18 February 2014

IQGAP1 controls tight junction formation through differential regulation of claudin recruitment

scientific article

IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton ⬇️

scientific article published on February 2, 2011

IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling

scientific article

IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling

scientific article published on 01 January 1999

IQGAP1 is a component of Cdc42 signaling to the cytoskeleton

scientific article (publication date: 5 July 2002)

IQGAP1 mediates the disruption of adherens junctions to promoteEscherichia coliK1 invasion of brain endothelial cells ⬇️

scientific article published on May 24, 2012

IQGAP1 promotes cell motility and invasion

scientific article published on 4 August 2003

IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance

scientific article

IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1, and Cdc42.

scientific article published on 11 August 2007

IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.

scientific article

IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells

scientific article

IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis

scientific article

IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin

scientific article (publication date: March 2002)

IQGAPs choreograph cellular signaling from the membrane to the nucleus

scientific article

IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis

scientific article

Identification and characterization of the Cdc42-binding site of IQGAP1

scientific article

Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2.

scientific article published on 17 September 2012

Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance

scientific article published on 28 October 2015

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

scientific article

Identification of insulin-stimulated phosphorylation sites on calmodulin

scientific article published on 01 May 1996

Implications of the revised criteria for diagnosis and classification of diabetes mellitus ⬇️

scientific article published on 01 December 1997

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer

scientific article

Insulin-dependent phosphorylation of calmodulin in rat hepatocytes

scientific article published on 01 November 1994

Insulin-stimulated phosphorylation of calmodulin ⬇️

scientific article published on August 15, 1992

Insulin-stimulated phosphorylation of calmodulin by rat liver insulin receptor preparations.

scientific article published in February 1988

Interference in an automated radial partition fluorescent immunoassay of thyrotropin associated with liver-function abnormalities.

scientific article published in July 1990

Interference of cerebrospinal fluid total protein measurement by povidone-iodine contamination

scientific article

Interpretation of hemoglobin A1c values

scientific article published on 01 June 2014

Investigation of 2 models to set and evaluate quality targets for hb a1c: biological variation and sigma-metrics.

scientific article published on 03 March 2015

Islet autoantibodies and type 1 diabetes: does the evidence support screening?

scientific article published on 20 December 2013

It's time for a better blood collection tube to improve the reliability of glucose results

scientific article published on January 2013

Measurement of circulating glucose concentrations: the time is now for consistency among methods and types of samples

scientific article published in September 2005

Measuring and reporting hemoglobin A1c ⬇️

scientific article published on July 15, 2012

Midkine concentrations in fine-needle aspiration of benign and malignant thyroid nodules.

scientific article published on 20 November 2014

Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies

scientific article published in May 1991

Multicentre evaluation of the Premier Hb9210 HbA1c analyser

scientific article

PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase.

scientific article

Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism

scientific article published on 01 January 2021

Phosphorylation by casein kinase II alters the biological activity of calmodulin ⬇️

scientific article published on April 1, 1992

Phosphorylation of calmodulin by plasma-membrane-associated protein kinase(s)

scientific article published on 01 November 1995

Phosphorylation of calmodulin by the epidermal-growth-factor-receptor tyrosine kinase

scientific article published on 01 September 1994

Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II.

scientific article

Phosphorylation selectively increases triiodothyronine receptor homodimer binding to DNA

scientific article published on 01 January 1994

Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cells

scientific article

Plasmonic chip tackles type 1 diabetes diagnosis

scientific article published on 5 February 2015

Point: The reporting of estimated glucose with hemoglobin A1c.

scientific article published on 18 February 2010

Position statement executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

scientific article

Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury.

scientific article published on October 1997

Predictive value of creatine kinase (CK)-MB for diagnosis of acute myocardial infarction after major noncardiac surgery

scientific article published on January 1, 1998

Proteomic analysis of ischemia-reperfusion injury upon human liver transplantation reveals the protective role of IQGAP1.

scientific article

Radial partition fluorescent immunoassay of thyrotropin. Analytic evaluation and clinical correlation

scientific article published on 01 January 1990

Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A.

scientific article

Rapid Classification and Identification of Multiple Microorganisms with Accurate Statistical Significance via High-Resolution Tandem Mass Spectrometry

scientific article published on 05 June 2018

Refining Measurement of Hemoglobin A1c

scientific article published on 20 June 2017

Regulation of MAP kinase signaling by calcium

scientific article published on 01 January 2010

Reporting hemoglobin A1c: do the units matter?

scientific article published on 22 July 2013

Response to Comment on Bergenstal et al. Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring. Diabetes Care 2018;41:2275-2280

scientific article published on 17 December 2018

Role of Glycated Proteins in the Diagnosis and Management of Diabetes: Research Gaps and Future Directions

scientific article published on August 2016

Role of IQGAP1 in endothelial barrier enhancement caused by OxPAPC.

scientific article published on 26 August 2016

Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling.

scientific article

Screening for diabetes: is it warranted?

scientific article

Self-association of IQGAP1: characterization and functional sequelae

scientific article published on 16 August 2005

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.

scientific article published on 16 October 2015

Status of hemoglobin A1c measurement and goals for improvement: from chaos to order for improving diabetes care

scientific article published on 09 December 2010

Structural Basis for Ca2+-induced Activation and Dimerization of Estrogen Receptor   by Calmodulin

scientific article

Targeting of calcium:calmodulin signals to the cytoskeleton by IQGAP1.

scientific article published on 29 November 2006

The IFCC Reference Measurement System for HbA1c: a 6-year progress report

scientific article published in February 2008

The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes

scientific article published on 5 November 2007

The National Glycohemoglobin Standardization Program: Over 20 Years of Improving Hemoglobin A1c Measurement

scientific article published on 05 December 2018

The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway.

scientific article published on 20 June 2013

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs

scientific article published on 9 August 2016

The biology of IQGAP proteins: beyond the cytoskeleton

scientific article

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.

scientific article

The carboxyl terminal segment of the c-Ki-ras 2 gene product mediates insulin-stimulated phosphorylation of calmodulin and stimulates insulin-independent autophosphorylation of the insulin receptor

scientific article published on 01 June 1989

The challenge of training pathologists in the 21st century

scientific article published on 16 June 2006

The diagnosis of diabetes is changing: how implementation of hemoglobin A1c will impact clinical laboratories.

scientific article published on 9 July 2009

The effect of IQGAP1 on Xenopus embryonic ectoderm requires Cdc42

scientific article published on 02 October 2001

The enigma of insulin resistance and hypertension.

scientific article

The interaction of calmodulin and polylysine as studied by 1H NMR spectroscopy and sedimentation equilibrium centrifugation

scientific article

The mechanism of insulin action

scientific article published on 01 August 1993

The national glycohemoglobin standardization program: a five-year progress report.

scientific article

The role of scaffold proteins in MEK/ERK signalling

scientific article

The structural effects of endogenous and exogenous Ca2+/calmodulin on phosphorylase kinase

scientific article published on 01 October 1997

The surveillance error grid

scientific article

The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.

scientific article

The utility of patient age in evaluating prostate cancer

scientific article published on 01 March 1997

Therapy: Intensive glucose control in the ICU: is sugar nice?

scientific article published in September 2009

Tight glucose control in critically ill adults

scientific article published on 01 December 2008

Tight glucose control in critically ill patients: should glucose meters be used?

scientific article published on 25 June 2009

Tight glucose control in the intensive care unit: are glucose meters up to the task?

scientific article published on 21 November 2008

Time to positivity of a rapid bedside assay for cardiac-specific troponin T predicts prognosis in acute coronary syndromes: a Thrombolysis in Myocardial Infarction (TIMI) 11A substudy

scientific article published on February 1998

Translating hemoglobin A1c into average blood glucose: implications for clinical chemistry

scientific article

Troponin T as a marker for myocardial ischemia in patients undergoing major noncardiac surgery

scientific article published on May 1996

Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function

scientific article published on 21 October 2020

Tyrosine-Phosphorylated Calmodulin Has Reduced Biological Activity

scientific article published on 01 November 1994

Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42

scientific article published on 24 February 2020

Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2.

scientific article published on 22 January 2018

Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge

scientific article published on September 2013

β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1

scientific article (publication date: 2013)

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