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List of works by Matthew C. Walker

'Brain activation and hypothalamic functional connectivity during human non-rapid eye movement sleep: an EEG/fMRI study'--its limitations and an alternative approach

scientific article published in July 2007

A 'sustain pedal' in the hippocampus?

scientific article published in February 2010

A case of late-onset Kleine-Levin syndrome responding to lamotrigine

scientific article published on 29 May 2008

A community study in Cornwall UK of sudden unexpected death in epilepsy (SUDEP) in a 9-year population sample

scientific article published on 22 February 2014

A fitful night's sleep

scientific article published in August 2010

A functional role for both -aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus

scientific article published on 4 February 2013

A novel telemetry system for recording EEG in small animals.

scientific article published on 26 July 2011

A self-activating intrinsic brake on bursting in CA3 neurons

scientific article published in March 2009

A study of the electro-haemodynamic coupling using simultaneously acquired intracranial EEG and fMRI data in humans.

scientific article

Activation of calcineurin underlies altered trafficking of α2 subunit containing GABAA receptors during prolonged epileptiform activity

scientific article published on 22 September 2014

Acute down-regulation of adenosine A(1) receptor activity in status epilepticus

scientific article

Adult epilepsy

scientific article

Adult-onset NREM parasomnia with hypnopompic hallucinatory pain: a case report

scientific article published on February 2013

Ammonia: what adult neurologists need to know

scientific article published on 11 December 2020

Astrocytic GABA transporter activity modulates excitatory neurotransmission

scientific article

Asymmetric hemispheric representation of periictal heart rate modulation is individually lateralised

scientific article published on 01 June 2011

Autonomic status epilepticus in Panayiotopoulos syndrome and other childhood and adult epilepsies: a consensus view

scientific article published on 18 April 2007

Basic physiology of limbic status epilepticus

scientific article published on December 2009

Blackouts in the toilet: a case of micturition-induced reflex epilepsy

scientific article published on 24 February 2014

Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model

scientific article published on 25 March 2018

Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline

scientific article published on 13 January 2017

Case of simple partial status epilepticus in occipital lobe epilepsy misdiagnosed as migraine: clinical, electrophysiological, and magnetic resonance imaging characteristics.

scientific article

Cavernoma-related epilepsy: review and recommendations for management--report of the Surgical Task Force of the ILAE Commission on Therapeutic Strategies

scientific article

Characterisation and imaging of cortical impedance changes during interictal and ictal activity in the anaesthetised rat

scientific article

Characterisation of cortical activity in response to deep brain stimulation of ventral-lateral nucleus: modelling and experiment

scientific article published on 17 July 2009

Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.

scientific article

Chemical-genetic attenuation of focal neocortical seizures

scientific article

Cholinergic axons modulate GABAergic signaling among hippocampal interneurons via postsynaptic alpha 7 nicotinic receptors

scientific article

Clinical advances in the understanding, diagnosis, and treatment of epilepsy

scientific article published on 01 April 2020

Clinical pharmacokinetics of new antiepileptic drugs

scientific article published on January 1995

Comment on "Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity".

scientific article published in September 2004

Comparison of serum, cerebrospinal fluid and brain extracellular fluid pharmacokinetics of lamotrigine

scientific article published in May 2000

Comparison of single- and repeated-dose pharmacokinetics of diazepam

scientific article published in March 1998

Complex partial status

scientific article published on 01 July 1996

Computational sophistication at a single GABAergic connection.

scientific article published in September 2009

Concepts of connectivity and human epileptic activity

scientific article

Corrigendum to Simultaneous intracranial EEG fMRI of interictal epileptic discharges in humans [NeuroImage 54/1 (2011) 182–190]

scholarly article published in NeuroImage

Developing an Evidence-Based Epilepsy Risk Assessment eHealth Solution: From Concept to Market.

scientific article

Developments in antiepileptic drug therapy

scientific article published on April 1994

Diagnosis and treatment of nonconvulsive status epilepticus

scientific article

Diagnosis and treatment of status epilepticus on a neurological intensive care unit

scientific article

Different transporter systems regulate extracellular GABA from vesicular and non-vesicular sources

scientific article published on 13 March 2013

Difficulties in extrapolating from clinical trial data to clinical practice: The case of antiepileptic drugs ⬇️

scientific article published on August 1, 1997

Disorders of Consciousness, Intensive Care Neurology and Sleep

Do alterations in inter-ictal heart rate variability predict sudden unexpected death in epilepsy?

scientific article published on 10 September 2009

Do mossy fibers release GABA?

scientific article

Do seizures in patients with refractory epilepsy vary between wakefulness and sleep?

scientific article

Do subclinical electrographic seizure patterns affect heart rate and its variability?

scientific article published on 17 September 2009

Double-blind, placebo-controlled study of topiramate in patients with refractory partial epilepsy

scientific article published on 01 November 1996

EEG correlated functional MRI and postoperative outcome in focal epilepsy

scientific article

EEG-fMRI mapping of asymmetrical delta activity in a patient with refractory epilepsy is concordant with the epileptogenic region determined by intracranial EEG.

scientific article published on 20 March 2006

EEG–fMRI in Adults with Focal Epilepsy

article

Editorial

Emergency Treatment of Seizures and Status Epilepticus

Endogenous zinc inhibits GABA(A) receptors in a hippocampal pathway

scientific article published on 15 October 2003

Energy depletion in seizures: anaplerosis as a strategy for future therapies

scientific article published on 30 May 2012

Enhanced QT shortening and persistent tachycardia after generalized seizures

scientific article

Epilepsy Gene Therapy Using an Engineered Potassium Channel

article

Epilepsy and Related Disorders

Epilepsy awareness and emergency rescue training: Ignorance is bliss!

scientific article

Epilepsy emergency rescue training

scientific article

Epilepsy research methods update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms.

scientific article published on 13 October 2014

Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging.

scientific article

Epileptogenesis is associated with enhanced glutamatergic transmission in the perforant path

scientific article

Extrasynaptic GABAA receptors: form, pharmacology, and function

scientific article published on October 2009

Extratemporal ictal clinical features in hippocampal sclerosis: their relationship to the degree of hippocampal volume loss and to the outcome of temporal lobectomy

scientific article

Falling status epilepticus mortality rates in England and Wales: 2001-2013?

scientific article

Febrile convulsions: a 'benign' condition?

scientific article

Fluoxetine and seizures

scientific article published on 01 September 1996

From theory to practice: Critical points in the 2017 ILAE classification of epileptic seizures and epilepsies

scientific article published on 01 February 2020

Furosemide terminates limbic status epilepticus in freely moving rats

scientific article published in September 2003

GABA uptake regulates cortical excitability via cell type-specific tonic inhibition

scientific article published in May 2003

GABA-independent GABAA receptor openings maintain tonic currents.

scientific article published on February 2013

GABAA receptor subunit specificity: a tonic for the excited brain

GABAA receptors at hippocampal mossy fibers

scientific article

Gelastic seizures: incidence, clinical and EEG features in adult patients undergoing video-EEG telemetry.

scientific article published on 17 December 2014

Gene therapy in epilepsy-is it time for clinical trials?

scientific article

Gene therapy in status epilepticus

scientific article

Generalized spike and waves: effect of discharge duration on brain networks as revealed by BOLD fMRI

scientific article

Halothane as a neuroprotectant during constant stimulation of the perforant path

scientific article published in March 1999

Has the Time Come to Stratify and Score SUDEP Risk to Inform People With Epilepsy of Their Changes in Safety?

scientific article published on 27 April 2018

Hippocampal Sclerosis: Causes and Prevention

scientific article published on 10 June 2015

Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery

scientific article published in October 2017

Hypersomnia with dilated pupils in adenosine monophosphate deaminase (AMPD) deficiency

scientific article

I(h)-mediated depolarization enhances the temporal precision of neuronal integration. ⬇️

scientific article

Imaging haemodynamic changes related to seizures: comparison of EEG-based general linear model, independent component analysis of fMRI and intracranial EEG.

scientific article published on 4 June 2010

Impact of psychogenic nonepileptic seizures on epilepsy presurgical investigation and surgical outcomes

In response to commentary on cavernoma-related epilepsy: Review and recommendations for management-Report of the surgical task force of the ILAE commission on therapeutic strategies

In response: Comment on falling status epilepticus mortality rates in England and Wales: 2001-2013

article

In vitro effects of neuropeptide Y in rat neocortical and hippocampal tissue

Increased NKCC1 expression in refractory human epilepsy

scientific article published on 6 March 2007

Independent component analysis of interictal fMRI in focal epilepsy: Comparison with general linear model-based EEG-correlated fMRI

article

Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP.

scientific article published in December 2009

KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy

scientific article published on 12 March 2018

Letter Re "Status epilepticus-related etiology, incidence and mortality: A meta-analysis" by Lv R-J et al., 2017.

scientific article published in November 2017

Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus

scientific article published in March 2006

Long-term use of lamotrigine and vigabatrin in severe refractory epilepsy: audit of outcome

scientific article published on November 1996

Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis

scientific article

Loss of rapid eye movement sleep atonia in patients with REM sleep behavioral disorder, narcolepsy, and isolated loss of REM atonia

scientific article published on 15 October 2013

Machine learning as a diagnostic decision aid for patients with transient loss of consciousness

scientific article published on 01 April 2020

Mapping human preictal and ictal haemodynamic networks using simultaneous intracranial EEG-fMRI.

scientific article published on 23 March 2016

Mapping preictal and ictal haemodynamic networks using video-electroencephalography and functional imaging.

scientific article published in December 2012

Mechanisms of Antiepileptic Drug Action

article

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders.

scientific article

Microdialysis Study of the Neuropharmacokinetics of Phenytoin in Rat Hippocampus and Frontal Cortex

scientific article published on 01 May 1996

Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat.

scientific article published in February 2002

Monosynaptic GABAergic signaling from dentate to CA3 with a pharmacological and physiological profile typical of mossy fiber synapses

scientific article published in March 2001

Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus.

scientific article

NREM arousal parasomnias and their distinction from nocturnal frontal lobe epilepsy: a video EEG analysis.

scientific article published on December 2009

Network meta-analysis and the comparison of efficacy and tolerability of anti-epileptic drugs for treatment of refractory focal epilepsy.

scientific article published on November 2013

Neural ECM and epilepsy

scientific article

Neurological examination of the unconscious patient

scientific article published on 01 July 1999

Neuropeptides in epilepsy

scientific article published on 22 October 2013

Neuroprotection in epilepsy

scientific article published on January 2007

New anti-epileptic drugs

scientific article

New antiepileptic drug trials in developing countries: are they necessary?

scientific article published on September 1996

New experimental therapies for status epilepticus in preclinical development.

scientific article published on 16 July 2015

Non-communicating syringomyelia and neuromyelitis optica

scientific article

Non-convulsive status epilepticus presenting as a psychiatric condition

scientific article published in February 1996

Noncanonical spike-related BOLD responses in focal epilepsy

scientific article

Opportunities for improving animal welfare in rodent models of epilepsy and seizures

scientific article

Optimised induction of on-demand focal hippocampal and neocortical seizures by electrical stimulation

scientific article published on 14 August 2020

Optogenetic and chemogenetic therapies for epilepsy

scientific article published on 05 September 2019

Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy

scientific article

Outwardly rectifying tonically active GABAA receptors in pyramidal cells modulate neuronal offset, not gain.

scientific article published in December 2009

Overtreatment with Antiepileptic Drugs

P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study

scientific article published on 18 June 2013

Panic symptoms in transient loss of consciousness: Frequency and diagnostic value in psychogenic nonepileptic seizures, epilepsy and syncope.

scientific article published on 27 March 2017

Paroxysmal limb dyskinesia induced by weight: an unusual case of cortical reflex seizures

scientific article published on 28 September 2011

Pathologic cardiac repolarization in pharmacoresistant epilepsy and its potential role in sudden unexpected death in epilepsy: A case-control study

scientific article published on 08 October 2009

Pathophysiology of status epilepticus

Peri-ictal atrioventricular conduction block in a patient with a lesion in the left insula: case report and review of the literature

scientific article published on 22 August 2009

Peri-ictal heart rates depend on seizure-type

Periodic lateralized epileptiform discharges (PLEDs) as the sole electrographic correlate of a complex partial seizure

scientific article published on 01 March 2005

Personalized translational epilepsy research - Novel approaches and future perspectives: Part I: Clinical and network analysis approaches.

scientific article published on 13 September 2017

Personalized translational epilepsy research - Novel approaches and future perspectives: Part II: Experimental and translational approaches.

scientific article published on 13 September 2017

Pharmacogenetic aspects

Plasticity of GABA(B) receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus.

scientific article published in December 2003

Postictal generalized electroencephalographic suppression is associated with generalized seizures

scientific article published on 14 May 2011

Postictal increase in T-wave alternans after generalized tonic-clonic seizures.

scientific article published on 20 September 2011

Potassium and sodium microdomains in thin astroglial processes: A computational model study.

scientific article published on 18 May 2018

Pre-ictal autonomic changes

scientific article

Predictors for being offered epilepsy surgery: 5-year experience of a tertiary referral centre.

scientific article published on 2 May 2015

Preeclampsia and gestational diabetes mellitus: pre-conception origins?

scientific article

Premature mortality in refractory partial epilepsy: does surgical treatment make a difference?

scientific article

Presynaptic, extrasynaptic and axonal GABAA receptors in the CNS: where and why?

scientific article published in January 2005

Progressive loss of phasic, but not tonic, GABAA receptor-mediated inhibition in dentate granule cells in a model of post-traumatic epilepsy in rats

scientific article published on 4 August 2011

Prolonged seizure activity impairs mitochondrial bioenergetics and induces cell death

scientific article published on 10 February 2012

Propofol in subanesthetic doses terminates status epilepticus in a rodent model

article

Proposal for a "phase II" multicenter trial model for preclinical new antiepilepsy therapy development.

scientific article published on August 2013

Pros and cons for the development of new antiepileptic drugs

scientific article published in January 2002

Pseudocataplexy and transient functional paralysis: a spectrum of psychogenic motor disorder

scientific article published in January 2010

Psychogenic nonepileptic seizure manifestations reported by patients and witnesses

scientific article published on 18 July 2011

Rapid eye movement sleep disturbances in Huntington disease

scientific article

Rapid onset transverse myelitis in adolescence: implications for pathogenesis and prognosis

scientific article

Recent advances in epilepsy

scientific article published on 04 March 2014

Regulation and role of REST and REST4 variants in modulation of gene expression in in vivo and in vitro in epilepsy models.

scientific article published on 7 July 2006

Regulation of excitability by extrasynaptic GABA(A) receptors

scientific article published on January 2008

Review: Is levetiracetam different from other antiepileptic drugs? Levetiracetam and its cellular mechanism of action in epilepsy revisited ⬇️

scientific article published on July 1, 2008

Rufinamide

article

Seize the moment that is thine: how should we define seizures?

scientific article

Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation

scientific article

Seizure control by decanoic acid through direct AMPA receptor inhibition

scientific article

Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency.

scientific article published on 17 October 2014

Seizure control by ketogenic diet-associated medium chain fatty acids

scientific article (publication date: June 2013)

Seizure localization using ictal phase-locked high gamma: A retrospective surgical outcome study

scientific article

Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid

scientific article

Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model

scientific article published on 14 December 2018

Severe ictal hypoxemia following focal, subclinical temporal electrographic scalp seizure activity

scientific article published on 18 April 2012

Simultaneous intracranial EEG and fMRI of interictal epileptic discharges in humans

scientific article published on 11 August 2010

Status epilepticus in idiopathic generalized epilepsy

scientific article

Status epilepticus in the setting of acute encephalitis

scientific article published on January 2014

Status epilepticus on the intensive care unit ⬇️

scientific article published on April 1, 2003

Status epilepticus results in persistent overproduction of reactive oxygen species, inhibition of which is neuroprotective

scientific article

Status epilepticus: classification and pathophysiology

Steps to prevent SUDEP: the validity of risk factors in the SUDEP and seizure safety checklist: a case control study

scientific article published on 22 June 2016

Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity

scientific article published on 23 March 2015

Synergism between topiramate and budipine in refractory status epilepticus in the rat.

scientific article published in November 2004

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

scientific article

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

scientific article published on 30 May 2017

Tetanus Toxin Model of Focal Epilepsy

article

The LIM homeodomain protein Lhx6 regulates maturation of interneurons and network excitability in the mammalian cortex

scientific article

The Role of Animal Models in the Study of Epileptogenesis

The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

scientific article published on 29 August 2011

The attitude of courts in England to compensation for post-traumatic epilepsy.

scientific article

The drug treatment of status epilepticus in Europe: Consensus document from a workshop at the first London Colloquium on Status Epilepticus

scientific article published on 01 July 2008

The effect of posterior hypothalamus region deep brain stimulation on sleep

scientific article

The epidemiology and management of status epilepticus ⬇️

scientific article published on April 1, 1998

The impact of new antiepileptic drugs on the prognosis of epilepsy: seizure freedom should be the ultimate goal

scientific article published on April 1996

The intensive care treatment of convulsive status epilepticus in the UK. Results of a national survey and recommendations.

scientific article published in February 1995

The long-term course of temporal lobe epilepsy: From unilateral to bilateral interictal epileptiform discharges in repeated video-EEG monitorings

scientific article published on 18 January 2017

The potential of brain stimulation in status epilepticus ⬇️

scientific article published on October 1, 2011

The problems facing epilepsy therapy ⬇️

scientific article published on February 19, 2013

The proceedings of the First London Colloquium on Status Epilepticus--University College London, April 12-15, 2007. Introduction

scientific article published in January 2007

The proceedings of the First London Colloquium on Status Epilepticus—University College London, April 12–15, 2007

article by Simon D. Shorvon et al published November 2007 in Epilepsia

The search for better epilepsy treatments: from slime mould to coconuts

scientific article published on December 2013

The ups and downs of seizure activity ⬇️

scientific article published on May 1, 2011

The utility of polysomnography for the diagnosis of NREM parasomnias: an observational study over 4 years of clinical practice

scientific article

Therapies for narcolepsy with or without cataplexy: evidence-based review.

scientific article published on December 2007

Tonic GABA(A) receptor-mediated currents in human brain

scientific article published in August 2006

Tonic GABAA conductance decreases membrane time constant and increases EPSP-spike precision in hippocampal pyramidal neurons

scientific article published on 25 December 2013

Tonic GABAA receptor-mediated signaling

Tonic GABAA receptor-mediated signalling in temporal lobe epilepsy ⬇️

scientific article published on April 19, 2012

Tonically active GABA A receptors: modulating gain and maintaining the tone.

scientific article published on May 2004

Too long or too short? New insights into abnormal cardiac repolarization in people with chronic epilepsy and its potential role in sudden unexpected death

scientific article published on 08 April 2010

Topiramate: a new antiepileptic drug for refractory epilepsy

scientific article published on September 1996

Treatment of nonconvulsive status epilepticus

scientific article published on January 2007

Treatment of seizure emergencies: convulsive and non-convulsive status epilepticus.

scientific article

Treatment options in juvenile myoclonic epilepsy

scientific article published in August 2011

Valproate decreases frequency facilitation at mossy fiber—CA3 synapses after status epilepticus ⬇️

scientific article published on December 16, 2010

Value of patient-reported symptoms in the diagnosis of transient loss of consciousness

scientific article

Value of witness observations in the differential diagnosis of transient loss of consciousness

scientific article published on 25 January 2019

Vigabatrin and Carbamazepine Monotherapy for Newly Diagnosed Epilepsy

scientific article published on 01 June 1996

What non-neuronal mechanisms should be studied to understand epileptic seizures?

scientific article

When do psychogenic nonepileptic seizures occur on a video/EEG telemetry unit?

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