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List of works by Martin Köbel

A COEUR cohort study of SATB2 expression and its prognostic value in ovarian endometrioid carcinoma

scientific article published on 20 April 2019

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

scientific article published on 25 June 2019

A comparison of p53 and WT1 immunohistochemical expression patterns in tubo-ovarian high-grade serous carcinoma before and after neoadjuvant chemotherapy.

scientific article published in June 2017

A limited panel of immunomarkers can reliably distinguish between clear cell and high-grade serous carcinoma of the ovary

scientific article

A rare case of NUT midline carcinoma

scientific article published on 08 October 2012

ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus

scientific article published on 01 October 2018

Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes

scientific article published on 27 February 2012

Accelerating type-specific ovarian carcinoma research: Calculator for Ovarian Subtype Prediction (COSP) is a reliable high-throughput tool for case review

scientific article published on 02 September 2013

Adult-type granulosa cell tumors and FOXL2 mutation.

scientific article published on December 2009

An Immunohistochemical Algorithm for Ovarian Carcinoma Typing

scientific article

Architectural patterns of ovarian/pelvic high-grade serous carcinoma.

scientific article

Association of Hormone Receptor Expression with Survival in Ovarian Endometrioid Carcinoma: Biological Validation and Clinical Implications

scientific article published on 27 February 2017

BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma

scientific article published on 27 January 2012

Biomarker expression in pelvic high-grade serous carcinoma: comparison of ovarian and omental sites

scientific article published on 01 July 2011

Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium

scientific article published on 23 July 2013

Calibration and Optimization of p53, WT1, and Napsin A Immunohistochemistry Ancillary Tests for Histotyping of Ovarian Carcinoma: Canadian Immunohistochemistry Quality Control (CIQC) Experience.

scientific article published on 23 November 2015

Canadian Consensus-based and Evidence-based Guidelines for Benign Endometrial Pathology Reporting in Biopsy Material

scientific article published on 24 January 2018

Canadian high risk endometrial cancer (CHREC) consortium: analyzing the clinical behavior of high risk endometrial cancers

scientific article published on 6 September 2015

Case report: Hydropic leiomyoma of the uterus presenting in pregnancy: imaging features

scientific article published on 01 August 2009

Cervical Adenocarcinoma: A Comparison of the Reproducibility of the World Health Organization 2003 and 2014 Classifications

scientific article published on 01 April 2018

Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers

scientific article published on 27 March 2018

Characterization of the molecular differences between ovarian endometrioid carcinoma and ovarian serous carcinoma

scientific article published in February 2010

Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010.

scientific article published on 26 January 2011

Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations

scientific article

Combined CCNE1 high-level amplification and overexpression is associated with unfavourable outcome in tubo-ovarian high-grade serous carcinoma

scientific article published on 11 May 2020

Combined oral contraceptive use before the first birth and epithelial ovarian cancer risk

scientific article published on 13 December 2016

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas

scientific article published on 26 August 2016

Critical molecular abnormalities in high-grade serous carcinoma of the ovary

scientific article published on August 2008

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

scientific article published on 03 November 2020

Cytokine-suppressive anti-inflammatory drugs (CSAIDs) inhibit invasion and MMP-1 production of ovarian carcinoma cells

scientific article published in May 2003

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Diagnosis of Ovarian Carcinoma Histotype Based on Limited Sampling: A Prospective Study Comparing Cytology, Frozen Section, and Core Biopsies to Full Pathologic Examination

scientific article

Dicer and Drosha in ovarian cancer

scientific article published in March 2009

Differences in tumor type in low-stage versus high-stage ovarian carcinomas

scientific article

Differentially methylated loci distinguish ovarian carcinoma histological types: evaluation of a DNA methylation assay in FFPE tissue

scientific article published on 24 September 2013

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

scientific article published on 12 October 2017

EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

scientific article published on 23 June 2017

Efficient molecular subtype classification of high-grade serous ovarian cancer

scientific article published on 30 April 2015

Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma

scientific article

Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes

scientific article published on 27 March 2021

Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma

scientific article published on 31 July 2020

Endometrial Carcinomas With Clear Cells: A Study of a Heterogeneous Group of Tumors Including Interobserver Variability, Mutation Analysis, and Immunohistochemistry With HNF-1β.

scientific article published on 3 April 2015

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study

scientific article

Exploring the Clinical Impact of Predictive Biomarkers in Serous Ovarian Carcinomas

scientific article published on 16 October 2019

Expression of PD-L1 and presence of CD8-positive T cells in pre-treatment specimens of locally advanced cervical cancer

scientific article

Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma

scientific article published on March 2002

Expression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: correlation with tumour grading and prognosis

scientific article

Expression of neutral endopeptidase (NEP/CD10) on pancreatic tumor cell lines, pancreatitis and pancreatic tumor tissues

scientific article published on June 2007

Ezrin expression is related to poor prognosis in FIGO stage I endometrioid carcinomas

scientific article published on 01 April 2006

Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma.

scientific article published on April 2006

FIGO Stage Is the Strongest Prognostic Factor in Adenocarcinoma of the Uterine Cervix

scientific article published on 19 April 2019

Frequent Mismatch Repair Protein Deficiency in Mixed Endometrioid and Clear Cell Carcinoma of the Endometrium

scientific article published on 20 January 2017

Frequent loss of claudin-4 expression in dedifferentiated and undifferentiated endometrial carcinomas.

scientific article published on 19 April 2018

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium

scientific article

HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy

scientific article

High-grade Endometrioid Carcinoma of the Ovary: A Clinicopathologic Study of 30 Cases.

scientific article published on 5 January 2018

High-grade endometrial carcinoma: serous and grade 3 endometrioid carcinomas have different immunophenotypes and outcomes

scientific article published on July 2010

Histopathological features of endometrial carcinomas associated with POLE mutations: implications for decisions about adjuvant therapy

scientific article published on 28 September 2015

History of Comorbidities and Survival of Ovarian Cancer Patients, Results from the Ovarian Cancer Association Consortium

scientific article published on September 2017

Histotype classification of ovarian carcinoma: A comparison of approaches

scientific article published on 16 August 2018

Histotype predicts the curative potential of radiotherapy: the example of ovarian cancers

scientific article

Histotype-genotype correlation in 36 high-grade endometrial carcinomas.

scientific article published in September 2013

Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer.

scientific article

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article

IGF2BP3 (IMP3) expression is a marker of unfavorable prognosis in ovarian carcinoma of clear cell subtype

scientific article published on 09 January 2009

Iatrogenic endometriosis harbors somatic cancer-driver mutations

scientific article published on 01 January 2019

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Immunohistochemical Profiling of Endometrial Serous Carcinoma.

scientific article

Immunohistochemical characterization of prototypical endometrial clear cell carcinoma--diagnostic utility of HNF-1β and oestrogen receptor

scientific article published on 07 December 2013

Immunophenotypic features of dedifferentiated endometrial carcinoma - insights from BRG1/INI1-deficient tumours

scientific article published on 22 April 2016

Implementation of a Canadian external quality assurance program for breast cancer biomarkers: an initiative of Canadian Quality Control in immunohistochemistry (cIQc) and Canadian Association of Pathologists (CAP) National Standards Committee/Immuno

scientific article

Incidental nonuterine high-grade serous carcinomas arise in the fallopian tube in most cases: further evidence for the tubal origin of high-grade serous carcinomas

scientific article published in March 2015

Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.

scientific article

Influence of various cytokines on adhesion and migration of the colorectal adenocarcinoma cell line HRT-18.

scientific article

Interleukin-10 in serous ovarian carcinoma cell lines.

scientific article

Interobserver Agreement in Endometrial Carcinoma Histotype Diagnosis Varies Depending on The Cancer Genome Atlas (TCGA)-based Molecular Subgroup.

scientific article published in February 2017

Interpretation of P53 Immunohistochemistry in Endometrial Carcinomas: Toward Increased Reproducibility

scientific article published on 6 March 2018

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

scientific article

Letter in response to: McAlpine J, Leon-Castillo A, Bosse T. The rise of a novel classification system for endometrial carcinoma; integration of molecular subclasses. J Pathol 2018; 244: 538-549.

scientific article published on 7 March 2018

Letter to the editor regarding 'Roh MH, Lassin Y, Miron A et al. High-grade fimbrial-ovarian carcinomas are unified by p53, PTEN and PAX2 expression'

scientific article published on 01 September 2011

Loss of switch/sucrose non-fermenting complex protein expression in undifferentiated gastrointestinal and pancreatic carcinomas

scientific article published on 15 May 2020

Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas.

scientific article published on 08 January 2016

Low junctional adhesion molecule-A expression is associated with an epithelial to mesenchymal transition and poorer outcomes in high-grade serous carcinoma of uterine adnexa

scientific article published on 08 June 2020

MMR deficiency is common in high-grade endometrioid carcinomas and is associated with an unfavorable outcome

scientific article published on 11 August 2013

Molecular Analysis of Mixed Endometrial Carcinomas Shows Clonality in Most Cases.

scientific article published on 21 October 2015

Molecular Pathology of Ovarian Carcinomas.

scientific article published on 22 February 2011

Molecular alterations in indolent, aggressive and recurrent ovarian low-grade serous carcinoma

scientific article published on 30 August 2016

Molecular characterization of low-grade serous ovarian carcinoma identifies genomic aberrations according to hormone receptor expression

scientific article published on 29 June 2022

Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: Earlier prognostic information to guide treatment

scientific article published on 13 July 2016

Morphologic Reproducibility, Genotyping, and Immunohistochemical Profiling Do Not Support a Category of Seromucinous Carcinoma of the Ovary

scientific article published on 25 January 2017

Morphologic and Molecular Characteristics of Mixed Epithelial Ovarian Cancers.

scientific article

Morphologic spectrum of immunohistochemically characterized clear cell carcinoma of the ovary: a study of 155 cases

scientific article published on January 2011

Mucinous carcinomas of the ovary and colorectum: different organ, same dilemma.

scientific article published on 25 May 2011

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

scientific article published on 10 June 2009

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer

scientific article published in March 2018

Napsin A: Another milestone in the subclassification of ovarian carcinoma

scientific article published on 01 December 2014

Nuclear β-catenin and CDX2 Expression in Ovarian Endometrioid Carcinoma Identify Patients with Favorable Outcome

scientific article published on 01 February 2019

Oncogenic mutations in histologically normal endometrium: the new normal?

scientific article published on 22 July 2019

Optimized p53 immunohistochemistry is an accurate predictor of TP53 mutation in ovarian carcinoma.

scientific article published on 13 July 2016

Outcomes of Incidental Fallopian Tube High-Grade Serous Carcinoma and Serous Tubal Intraepithelial Carcinoma in Women at Low Risk of Hereditary Breast and Ovarian Cancer

scientific article

Ovarian Carcinoma Histotype: Strengths and Limitations of Integrating Morphology With Immunohistochemical Predictions

scientific article published on 01 July 2019

Ovarian Endometrioid Carcinoma Misdiagnosed as Mucinous Carcinoma: An Underrecognized Problem

scientific article published on 01 November 2019

Ovarian carcinoma histotype determination is highly reproducible, and is improved through the use of immunohistochemistry.

scientific article published on 07 March 2014

Ovarian carcinoma subtypes are different diseases: implications for biomarker studies

scientific article

Ovarian carcinoma. Do the subtypes reflect different diseases?

scientific article published in November 2008

PIK3CA missense mutation is associated with unfavorable outcome in grade 3 endometrioid carcinoma but not in serous endometrial carcinoma.

scientific article published on 19 November 2013

PIK3CA mutational status and overall survival in patients with cervical cancer treated with radical chemoradiotherapy

scientific article published on 22 December 2012

POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium.

scientific article

Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma.

scientific article published on 10 July 2015

Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium

scientific article published on 3 January 2017

Primary ovarian mucinous carcinoma of intestinal type: significance of pattern of invasion and immunohistochemical expression profile in a series of 31 cases

scientific article published on 01 March 2010

Progesterone receptor expression is associated with longer overall survival within high-grade histotypes of endometrial carcinoma: A Canadian high risk endometrial cancer consortium (CHREC) study

scientific article published on 9 April 2016

Prognostic gene expression signature for high-grade serous ovarian cancer

scientific article published on 27 May 2020

Prognostic role and implications of mutation status of tumor suppressor gene ARID1A in cancer: a systematic review and meta-analysis

scientific article published on 8 September 2015

Prognostic value of progesterone receptor expression in tubo-ovarian high-grade serous carcinoma of the coeur cohort

scientific article published on 15 January 2019

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

scientific article

Proteomics-Derived Biomarker Panel Improves Diagnostic Precision to Classify Endometrioid and High-grade Serous Ovarian Carcinoma

scientific article published on 12 April 2019

Quantification of ER/PR expression in ovarian low-grade serous carcinoma

scientific article published on 24 October 2012

Re: "A low-grade ovarian carcinoma case with coincident LOH of PTCH1 and BRCA1, and a mutation in BRCA1," Int J Gyn Pathol 2012 May;31: 264-271.

scientific article published in March 2013

Recent alcohol consumption and risk of incident ovarian carcinoma: a pooled analysis of 5,342 cases and 10,358 controls from the Ovarian Cancer Association Consortium

scientific article

Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

scientific article published on 28 July 2020

Regulation of cell growth and the expression of extracellular matrix proteins in colorectal adenocarcinoma: a fibroblast-tumor cell coculture model to study tumor-host interactions in vitro

scientific article published in January 2003

Reproducibility of histological cell type in high-grade endometrial carcinoma

scientific article published on 28 June 2013

Significant frequency of MSH2/MSH6 abnormality in ovarian endometrioid carcinoma supports histotype-specific Lynch syndrome screening in ovarian carcinomas

scientific article

Smoking may modify the association between neoadjuvant chemotherapy and survival from ovarian cancer

scientific article

Specimen quality evaluation in Canadian biobanks participating in the COEUR repository

scientific article published in April 2013

Survival Following Chemotherapy in Ovarian Clear Cell Carcinoma Is Not Associated with Pathological Misclassification of Tumor Histotype

scientific article published on 09 April 2019

Synchronous Ovarian and Appendiceal Mucinous Neoplasms in the Absence of Pseudomyxoma Peritonei

scientific article published on 17 November 2016

Synchronous endometrial and ovarian carcinomas: predictors of risk and associations with survival and tumor expression profiles

scientific article published on 13 February 2017

Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors

scientific article

Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are Uncommon

scientific article published on 01 April 2019

Targeted mutation analysis of endometrial clear cell carcinoma

scientific article

Tea, coffee, and caffeinated beverage consumption and risk of epithelial ovarian cancers

scientific article published on 27 October 2016

The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma.

scientific article published on 20 January 2012

The biological and clinical value of p53 expression in pelvic high-grade serous carcinomas.

scientific article

The diagnostic utility of TP53 and CDKN2A to distinguish ovarian high-grade serous carcinoma from low-grade serous ovarian tumors.

scientific article published on 05 April 2013

The fallopian tube: primary site of most pelvic high-grade serous carcinomas.

scientific article published on January 2009

The molecular origin and taxonomy of mucinous ovarian carcinoma

scientific article published on 02 September 2019

Treatment related outcomes in high-risk endometrial carcinoma: Canadian high risk endometrial cancer consortium (CHREC).

scientific article published on 4 February 2016

Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma.

scientific article published on 7 July 2008

Tumor type and substage predict survival in stage I and II ovarian carcinoma: insights and implications.

scientific article published on 12 October 2009

Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer

scientific article

Type-specific response to neoadjuvant chemotherapy: ovarian high-grade serous carcinoma versus colorectal mucinous carcinoma

scientific article published on 01 July 2012

Undifferentiated Endometrial Carcinomas Show Frequent Loss of Core Switch/Sucrose Nonfermentable Complex Proteins.

scientific article published on 31 August 2017

You won't believe this old test … that does cheap single-cell mutation detection

scientific article published on 01 July 2018

[Diagnosis and differential diagnosis of cervical adenocarcinoma]

scientific article published on 01 November 2011

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 22 March 2023

p53 immunohistochemistry is an accurate surrogate for TP53 mutational analysis in endometrial carcinoma biopsies

scientific article published on 29 January 2020