List of works - Amit V. Pandey

A colorimetric assay for heme in biological samples using 96-well plates

scientific article

A novel GH-1 gene mutation (GH-P59L) causes partial GH deficiency type II combined with bioinactive GH syndrome

scientific article published on 4 May 2011

Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase

scientific article published on 25 August 2017

Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase

scientific article published on 21 August 2010

Assay of beta-hematin formation by malaria parasite

scientific article published in June 1999

Bioactivity of Curcumin on the Cytochrome P450 Enzymes of the Steroidogenic Pathway

scientific article published on 17 September 2019

Biochemical analysis of mutations in P450 oxidoreductase

scientific article published on 01 December 2006

Bioinformatics Tools and Databases for the Study of Human Growth Hormone ⬇️

scientific article published on November 23, 2012

CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2.

scientific article published on 8 September 2017

Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 in CHO cells

scientific article

Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia

scientific article published on 27 August 2020

Characterization of a novel CYP19A1 (aromatase) R192H mutation causing virilization of a 46,XX newborn, undervirilization of the 46,XY brother, but no virilization of the mother during pregnancies

scientific article published on 4 April 2014

Characterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasia

scientific article

Clinical and Biochemical Consequences of P450 Oxidoreductase Deficiency ⬇️

scientific article published on December 16, 2010

Clinical and biochemical description of a novel CYP21A2 gene mutation 962_963insA using a new 3D model for the P450c21 protein

scientific article published on 01 July 2006

Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase

scientific article published on August 2007

Deletion of P399_E401 in NADPH cytochrome P450 oxidoreductase results in partial mixed oxidase deficiency

scientific article

Depolymerization of malarial hemozoin: a novel reaction initiated by blood schizontocidal antimalarials

scientific article published on February 1997

Differential effects of variations in human P450 oxidoreductase on the aromatase activity of CYP19A1 polymorphisms R264C and R264H

scientific article published on 24 October 2019

Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis

scientific article

Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function

scientific article published on 27 November 2017

Effect of Cysteamine on Mutant ASL Proteins with Cysteine for Arginine Substitutions

scientific article published on 01 April 2016

Endoplasmic Reticulum Stress Enhances Mitochondrial Metabolic Activity in Mammalian Adrenals and Gonads

scientific article published on 03 October 2016

FDXR variants cause adrenal insufficiency and atypical sexual development

scientific article published in 2024

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

scientific article published on 26 September 2020

Formation of haemozoin/beta-haematin under physiological conditions is not spontaneous

scientific article published in September 1996

GATA4 Variants in Individuals With a 46,XY Disorder of Sex Development (DSD) May or May Not Be Associated With Cardiac Defects Depending on Second Hits in Other DSD Genes

scientific article published on 4 April 2018

Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome.

scientific article published on 25 July 2016

Growth hormone (GH) deficiency type II: a novel GH-1 gene mutation (GH-R178H) affecting secretion and action

scientific article published in December 2009

HIV Drug Efavirenz Inhibits CYP21A2 Activity with Possible Clinical Implications

scientific article published on 28 June 2019

Hemozoin formation in malaria: a two-step process involving histidine-rich proteins and lipids

scientific article

IGHD II: A Novel GH-1 Gene Mutation (GH-L76P) Severely Affects GH Folding, Stability, and Secretion

scientific article

Identification and quantification of haemozoin: Some additional facts.

scientific article published in September 1996

Impact on CYP19A1 activity by mutations in NADPH cytochrome P450 oxidoreductase

scientific article

In silico and functional studies reveal novel loss-of-function variants of SRD5A2, but no variants explaining excess 5α-reductase activity

scientific article published on 28 January 2019

Inhibition of placental CYP19A1 activity remains as a valid hypothesis for 46,XX virilization in P450 oxidoreductase deficiency

scientific article published on 23 June 2020

Loss of the C terminus of melanocortin receptor 2 (MC2R) results in impaired cell surface expression and ACTH insensitivity

scientific article published on 20 October 2010

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.

scientific article published on 29 April 2018

Modeling of human P450 oxidoreductase structure by in silico mutagenesis and MD simulation

scientific article published on 8 September 2009

Modulation of human CYP19A1 activity by mutant NADPH P450 oxidoreductase

scientific article

Molecular Basis of CYP19A1 Deficiency in a 46,XX Patient With R550W Mutation in POR: Expanding the PORD Phenotype

scientific article published on 01 April 2020

Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome

scientific article (publication date: March 2004)

Mutations and polymorphisms in the human argininosuccinate lyase (ASL) gene

scientific article published on 25 November 2013

Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement

scientific article

NADPH P450 oxidoreductase: structure, function, and pathology of diseases

scientific article

NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.

scientific article

Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

scientific article published on July 2009

Novel CYP19A1 Mutations Extend the Genotype-Phenotype Correlation and Reveal the Impact on Ovarian Function

scientific article published on 10 March 2020

Of marsupials and men: "Backdoor" dihydrotestosterone synthesis in male sexual differentiation

scientific article published on 31 January 2013

P450 Oxidoreductase Deficiency: Loss of Activity Caused by Protein Instability From a Novel L374H Mutation

scientific article published on 7 September 2016

P450 Oxidoreductase deficiency: Analysis of mutations and polymorphisms

scientific article

P450 oxidoreductase deficiency

scientific article published on 01 November 2004

P450 oxidoreductase deficiency - a new form of congenital adrenal hyperplasia

scientific article published on January 2008

P450 oxidoreductase deficiency: a new disorder of steroidogenesis

scientific article

P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes

scientific article published in November 2004

Pharmacogenomics of human P450 oxidoreductase

scientific article

Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17

scientific article (publication date: 31 January 2003)

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

scientific article published on 19 March 2021

Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism

scientific article

Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17

scientific article

Restoration of mutant cytochrome P450 reductase activity by external flavin

scientific article

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis

scientific article published on 13 May 2015

STAR splicing mutations cause the severe phenotype of lipoid congenital adrenal hyperplasia: insights from a novel splice mutation and review of reported cases

scientific article published on 17 August 2013

Short stature in two siblings heterozygous for a novel bioinactive GH mutant (GH-P59S) suggesting that the mutant also affects secretion of the wild-type GH.

scientific article published on 15 February 2013

Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis

scientific article

Steroidogenesis of the testis -- new genes and pathways

scientific article published on 29 April 2014

Synthetic peptides corresponding to a repetitive sequence of malarial histidine rich protein bind haem and inhibit haemozoin formation in vitro

scientific article published on December 1997

Ten novel mutations in the NR5A1 gene cause disordered sex development in 46,XY and ovarian insufficiency in 46,XX individuals

scientific article

The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure

scientific article

The cytochrome P450 aromatase lacking exon 5 is associated with a phenotype of nonclassic aromatase deficiency and is also present in normal human steroidogenic tissues

scientific article published on 2 July 2007

Understanding the role of argininosuccinate lyase transcript variants in the clinical and biochemical variability of the urea cycle disorder argininosuccinic aciduria.

scientific article published on 17 October 2013

Unstable argininosuccinate lyase in variant forms of the urea cycle disorder argininosuccinic aciduria

scientific article

Variability in Loss of Multiple Enzyme Activities Due to the Human Genetic Variation P284T Located in the Flexible Hinge Region of NADPH Cytochrome P450 Oxidoreductase

scientific article published on 15 October 2019

Variability in human drug metabolizing cytochrome P450 CYP2C9, CYP2C19 and CYP3A5 activities caused by genetic variations in cytochrome P450 oxidoreductase

scientific article published on 23 May 2019

Vitamin D-Dependent Rickets Type 1 Caused by Mutations in CYP27B1 Affecting Protein Interactions With Adrenodoxin

scientific article published on 11 July 2016

Why Boys Will Be Boys: Two Pathways of Fetal Testicular Androgen Biosynthesis Are Needed for Male Sexual Differentiation

Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation

scientific article

List of works by Amit V. Pandey

A colorimetric assay for heme in biological samples using 96-well plates

A novel GH-1 gene mutation (GH-P59L) causes partial GH deficiency type II combined with bioinactive GH syndrome

Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase

Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase

Assay of beta-hematin formation by malaria parasite

Bioactivity of Curcumin on the Cytochrome P450 Enzymes of the Steroidogenic Pathway

Biochemical analysis of mutations in P450 oxidoreductase

Bioinformatics Tools and Databases for the Study of Human Growth Hormone ⬇️

CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2.

Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 in CHO cells

Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia

Characterization of a novel CYP19A1 (aromatase) R192H mutation causing virilization of a 46,XX newborn, undervirilization of the 46,XY brother, but no virilization of the mother during pregnancies

Characterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasia

Clinical and Biochemical Consequences of P450 Oxidoreductase Deficiency ⬇️

Clinical and biochemical description of a novel CYP21A2 gene mutation 962_963insA using a new 3D model for the P450c21 protein

Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase

Deletion of P399_E401 in NADPH cytochrome P450 oxidoreductase results in partial mixed oxidase deficiency

Depolymerization of malarial hemozoin: a novel reaction initiated by blood schizontocidal antimalarials

Differential effects of variations in human P450 oxidoreductase on the aromatase activity of CYP19A1 polymorphisms R264C and R264H

Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis

Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function

Effect of Cysteamine on Mutant ASL Proteins with Cysteine for Arginine Substitutions

Endoplasmic Reticulum Stress Enhances Mitochondrial Metabolic Activity in Mammalian Adrenals and Gonads

FDXR variants cause adrenal insufficiency and atypical sexual development

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

Formation of haemozoin/beta-haematin under physiological conditions is not spontaneous

GATA4 Variants in Individuals With a 46,XY Disorder of Sex Development (DSD) May or May Not Be Associated With Cardiac Defects Depending on Second Hits in Other DSD Genes

Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome.

Growth hormone (GH) deficiency type II: a novel GH-1 gene mutation (GH-R178H) affecting secretion and action

HIV Drug Efavirenz Inhibits CYP21A2 Activity with Possible Clinical Implications

Hemozoin formation in malaria: a two-step process involving histidine-rich proteins and lipids

IGHD II: A Novel GH-1 Gene Mutation (GH-L76P) Severely Affects GH Folding, Stability, and Secretion

Identification and quantification of haemozoin: Some additional facts.

Impact on CYP19A1 activity by mutations in NADPH cytochrome P450 oxidoreductase

In silico and functional studies reveal novel loss-of-function variants of SRD5A2, but no variants explaining excess 5α-reductase activity

Inhibition of placental CYP19A1 activity remains as a valid hypothesis for 46,XX virilization in P450 oxidoreductase deficiency

Loss of the C terminus of melanocortin receptor 2 (MC2R) results in impaired cell surface expression and ACTH insensitivity

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.

Modeling of human P450 oxidoreductase structure by in silico mutagenesis and MD simulation

Modulation of human CYP19A1 activity by mutant NADPH P450 oxidoreductase

Molecular Basis of CYP19A1 Deficiency in a 46,XX Patient With R550W Mutation in POR: Expanding the PORD Phenotype

Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome

Mutations and polymorphisms in the human argininosuccinate lyase (ASL) gene

Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement

NADPH P450 oxidoreductase: structure, function, and pathology of diseases

NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.

Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

Novel CYP19A1 Mutations Extend the Genotype-Phenotype Correlation and Reveal the Impact on Ovarian Function

Of marsupials and men: "Backdoor" dihydrotestosterone synthesis in male sexual differentiation

P450 Oxidoreductase Deficiency: Loss of Activity Caused by Protein Instability From a Novel L374H Mutation

P450 Oxidoreductase deficiency: Analysis of mutations and polymorphisms

P450 oxidoreductase deficiency

P450 oxidoreductase deficiency - a new form of congenital adrenal hyperplasia

P450 oxidoreductase deficiency: a new disorder of steroidogenesis

P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes

Pharmacogenomics of human P450 oxidoreductase

Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism

Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17

Restoration of mutant cytochrome P450 reductase activity by external flavin

Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis

STAR splicing mutations cause the severe phenotype of lipoid congenital adrenal hyperplasia: insights from a novel splice mutation and review of reported cases

Short stature in two siblings heterozygous for a novel bioinactive GH mutant (GH-P59S) suggesting that the mutant also affects secretion of the wild-type GH.

Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis

Steroidogenesis of the testis -- new genes and pathways

Synthetic peptides corresponding to a repetitive sequence of malarial histidine rich protein bind haem and inhibit haemozoin formation in vitro

Ten novel mutations in the NR5A1 gene cause disordered sex development in 46,XY and ovarian insufficiency in 46,XX individuals

The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure

The cytochrome P450 aromatase lacking exon 5 is associated with a phenotype of nonclassic aromatase deficiency and is also present in normal human steroidogenic tissues

Understanding the role of argininosuccinate lyase transcript variants in the clinical and biochemical variability of the urea cycle disorder argininosuccinic aciduria.

Unstable argininosuccinate lyase in variant forms of the urea cycle disorder argininosuccinic aciduria

Variability in Loss of Multiple Enzyme Activities Due to the Human Genetic Variation P284T Located in the Flexible Hinge Region of NADPH Cytochrome P450 Oxidoreductase

Variability in human drug metabolizing cytochrome P450 CYP2C9, CYP2C19 and CYP3A5 activities caused by genetic variations in cytochrome P450 oxidoreductase

Vitamin D-Dependent Rickets Type 1 Caused by Mutations in CYP27B1 Affecting Protein Interactions With Adrenodoxin

Why Boys Will Be Boys: Two Pathways of Fetal Testicular Androgen Biosynthesis Are Needed for Male Sexual Differentiation

Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation