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List of works by Tomás Sobrino

A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke.

scientific article

A higher body temperature is associated with haemorrhagic transformation in patients with acute stroke untreated with recombinant tissue-type plasminogen activator (rtPA).

scientific article published in February 2012

A novel mechanism of neuroprotection: Blood glutamate grabber

scientific article published on 02 October 2015

Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke

scientific article

Association of growth factors with arterial recanalization and clinical outcome in patients with ischemic stroke treated with tPA

scientific article published on 30 April 2010

Blood glutamate EAAT2-cell grabbing therapy in cerebral ischemia

scientific article published on 13 December 2018

Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality.

scientific article published on 4 March 2015

Blood levels of glutamate oxaloacetate transaminase are more strongly associated with good outcome in acute ischaemic stroke than glutamate pyruvate transaminase levels

scientific article published on 01 July 2011

CDP-choline treatment increases circulating endothelial progenitor cells in acute ischemic stroke.

scientific article published in July 2011

CGRP and PTX3 as Predictors of Efficacy of Onabotulinumtoxin Type A in Chronic Migraine: An Observational Study.

scientific article published on 13 November 2017

CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage.

scientific article published in June 2017

Cd34+ progenitor cells likely are involved in the good functional recovery after intracerebral hemorrhage in humans

scientific article published on 12 April 2011

Central nicotine induces browning through hypothalamic κ opioid receptor

scientific article published on 06 September 2019

Chronic periodontitis is associated with lacunar infarct: a case-control study

scientific article published on 15 July 2016

Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke

scientific article published on 22 August 2018

Corneal and conjunctival alteration of innate immune expression in first-degree relatives of keratoconus patients

scientific article published on 19 September 2020

Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke.

scientific article published on 21 August 2007

Early biomarkers of clinical-diffusion mismatch in acute ischemic stroke

scientific article published on 11 August 2011

Easy and Efficient Cell Tagging with Block Copolymer-Based Contrast Agents for Sensitive MRI Detection in Vivo

scientific article published on 18 April 2016

Endothelial Progenitor Cells as a Therapeutic Approach for Intracerebral Hemorrhage

scientific article published on 21 December 2016

Endothelial progenitor cells as a therapeutic option in intracerebral hemorrhage

scientific article published on April 2017

Endothelial progenitor cells: a new key for endothelial dysfunction in migraine

scientific article published on 18 July 2012

Generation and characterization of the human iPSC line IDISi001-A isolated from blood cells of a CADASIL patient carrying a NOTCH3 mutation.

scientific article published on 31 January 2018

Glutamate neurotoxicity is involved in the neurological damage in patients undergoing extracorporeal circulation

scientific article published on 15 January 2014

Glutamate oxaloacetate transaminase: a new key in the dysregulation of glutamate in migraine patients

scientific article published on 14 May 2013

Heads and Tails of Natriuretic Peptides: Neuroprotective Role of Brain Natriuretic Peptide

scientific article published on 4 December 2017

Hepatic damage and glutamate oxaloacetate transaminase elevations during fetal asphyxia

scientific article published on 01 February 2017

High blood glutamate oxaloacetate transaminase levels are associated with good functional outcome in acute ischemic stroke.

scientific article

High blood pressure and inflammation are associated with poor prognosis in lacunar infarctions

scientific article

High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke.

scientific article published on 29 October 2008

High pro-BNP levels predict the occurrence of atrial fibrillation after cryptogenic stroke

scientific article

High serum levels of endothelin-1 predict severe cerebral edema in patients with acute ischemic stroke treated with t-PA

scientific article published on 24 April 2008

High serum levels of growth factors are associated with good outcome in intracerebral hemorrhage.

scientific article published on 16 September 2009

High serum levels of leptin are associated with post-stroke depression.

scientific article published on 9 April 2009

High serum levels of pro-brain natriuretic peptide (pro BNP) identify cardioembolic origin in undetermined stroke.

scientific article published on January 2009

Higher Expression of Toll-Like Receptors 2 and 4 in Blood Cells of Keratoconus Patiens

scientific article published on 11 October 2017

Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia

scientific article

Hyperthermia in human ischemic and hemorrhagic stroke: similar outcome, different mechanisms

scientific article

Hyperthermia is a surrogate marker of inflammation-mediated cause of brain damage in acute ischaemic stroke.

scientific article

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

scientific article

Impact of benzodiazepines on brain FDG-PET quantification after single-dose and chronic administration in rats.

scientific article published on 10 September 2016

In vivo theranostics at the peri-infarct region in cerebral ischemia.

scientific article published on 12 December 2013

In vivo ultrasound-activated delivery of recombinant tissue plasminogen activator from the cavity of sub-micrometric capsules

scientific article published on 13 July 2019

Inclusion criteria update for the rat intraluminal ischaemic model for preclinical studies.

scientific article published on 19 December 2017

Increased Endothelial Progenitor Cell Levels are Associated with Good Outcome in Intracerebral Hemorrhage

scientific article published on 27 June 2016

Increased body iron stores are associated with poor outcome after thrombolytic treatment in acute stroke.

scientific article published on 30 November 2006

Increased expression of Toll-like receptors 2 and 4 is associated with poor outcome in intracerebral hemorrhage

scientific article published on 11 April 2012

Increased levels of circulating endothelial progenitor cells in patients with ischaemic stroke treated with statins during acute phase

scientific article published on 28 May 2012

Inflammation markers and prediction of post-stroke vascular disease recurrence: the MITICO study.

scientific article published on 27 February 2009

Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages

scientific article published on 15 June 2018

Inflammatory and neuroimmunomodulatory changes in acute cerebral ischemia.

scientific article published on 03 April 2009

Influence of the separation procedure on the properties of magnetic nanoparticles: Gaining in vitro stability and T1–T2 magnetic resonance imaging performance

scientific article published on 19 March 2016

Innate Immunity Biomarkers for Early Detection of Keratoconus

scientific article published on 19 September 2018

Interleukin-10 facilitates the selection of patients for systemic thrombolysis.

scientific article

Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia

scientific article published on 16 January 2017

Iron Deposits in Periaqueductal Gray Matter Are Associated with Poor Response to OnabotulinumtoxinA in Chronic Migraine

scientific article published on 28 July 2020

Iron deposition in periaqueductal gray matter as a potential biomarker for chronic migraine

scientific article published on 01 February 2019

Iron-related brain damage in patients with intracerebral hemorrhage

scientific article

Ischemic preconditioning: a novel target for neuroprotective therapy

scientific article published on 2 May 2006

Light-Emitting Diode Photobiomodulation After Cerebral Ischemia

scientific article published on 22 August 2019

Low Levels of Caveolin-1 Predict Symptomatic Bleeding After Thrombolytic Therapy in Patients With Acute Ischemic Stroke

scientific article published on 30 April 2018

Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking

scientific article

Micro- and macroalbuminuria predict hemorrhagic transformation in acute ischemic stroke.

scientific article published in October 2006

Microbleed burden and hematoma expansion in acute intracerebral hemorrhage

scientific article published on 06 August 2013

Mmp-9 immunoreactivity in acute migraine

scientific article

Model of Disc Degeneration in Rat Tail Induced Through a Vascular Isolation of Vertebral Endplates

scientific article published on 25 May 2017

Multifunctional Superparamagnetic Stiff Nanoreservoirs for Blood Brain Barrier Applications

scientific article published on 17 March 2019

NT-pro-BNP: A novel predictor of stroke risk after transient ischemic attack

scientific article published on 20 June 2019

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism

scientific article published on 21 October 2016

Neuronal excitotoxicity after carotid angioplasty and stent placement procedures

scientific article published on 22 March 2013

Neuroplasticity and cellular therapy in cerebral infarction.

scientific article published on November 2007

Neuroprotection afforded by antagonists of endothelin-1 receptors in experimental stroke

scientific article published on 4 September 2012

Neuroprotection by glutamate oxaloacetate transaminase in ischemic stroke: an experimental study

scientific article

Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA.

scientific article published on 14 December 2010

Neuroprotective effects of dexmedetomidine conditioning strategies: Evidences from an in vitro model of cerebral ischemia

scientific article published on 03 December 2015

Neurorepair versus neuroprotection in stroke.

scientific article published on 2 May 2006

Obesity Paradox in Ischemic Stroke: Clinical and Molecular Insights

scientific article published on 13 April 2019

Oxaloacetate: a novel neuroprotective for acute ischemic stroke

scientific article

Periodontal inflammation is related to increased serum calcitonin gene-related peptide levels in patients with chronic migraine

scientific article published on 27 May 2019

Periodontitis and vascular inflammatory biomarkers: an experimental in vivo study in rats

scientific article published on 03 October 2019

Periodontitis as a risk indicator and predictor of poor outcome for lacunar infarct

scientific article published on 29 November 2018

Periodontitis is associated with systemic inflammation and vascular endothelial dysfunction in patients with lacunar infarct

scientific article published on 29 November 2018

Plasma beta-amyloid 1-40 is associated with the diffuse small vessel disease subtype.

scientific article published on 20 August 2009

Platelet derived growth factor-CC isoform is associated with hemorrhagic transformation in ischemic stroke patients treated with tissue plasminogen activator.

scientific article published on 17 November 2012

Porphyromonas gingivalis lipopolysaccharide-induced periodontitis and serum amyloid-beta peptides

scientific article published on 16 January 2019

Positron Emission Tomography for the Development and Characterization of Corneal Permanence of Ophthalmic Pharmaceutical Formulations.

scientific article published on February 2017

Potential protective role of endogenous glutamate-oxaloacetate transaminase against glutamate excitotoxicity in fetal hypoxic-ischaemic asphyxia

scientific article published on 24 July 2015

Prestroke physical activity is associated with good functional outcome and arterial recanalization after stroke due to a large vessel occlusion

scientific article published on 21 May 2014

Prognostic value of blood interleukin-6 in the prediction of functional outcome after stroke: a systematic review and meta-analysis.

scientific article published on 24 July 2014

Protective Effects and Magnetic Resonance Imaging Temperature Mapping of Systemic and Focal Hypothermia in Cerebral Ischemia.

scientific article

Proteomic analysis shows differential protein expression in endothelial progenitor cells between healthy subjects and ischemic stroke patients.

scientific article published in December 2011

Quick adjustment of imaging tracer payload, for in vivo applications of theranostic nanostructures in the brain.

scientific article

RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis

scientific article published on 16 July 2021

Reported Prestroke Physical Activity Is Associated with Vascular Endothelial Growth Factor Expression and Good Outcomes after Stroke

scientific article published on 28 October 2016

Role of adipocytokines in the pathophysiology of migraine. A cross-sectional study

scientific article

Role of adipocytokines in the pathophysiology of migraine. A cross-sectional study.

scientific article published in January 2017

Serum cellular fibronectin and matrix metalloproteinase-9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke: a multicenter confirmatory study.

scientific article

Severe periodontitis is linked with increased peripheral levels of sTWEAK and PTX3 in chronic migraineurs

scientific article published on 20 May 2019

Single-Nucleotide Polymorphism 309T>G in the MDM2 Promoter Determines Functional Outcome After Stroke

scientific article published on 01 October 2018

Statins and stroke

scientific article published on 01 June 2008

Stroke with polyvascular atherothrombotic disease

scientific article published on 28 July 2009

Study of Protein Expression in Peri-Infarct Tissue after Cerebral Ischemia.

scientific article

Subclinical keratoconus and inflammatory molecules from tears.

scientific article published on 19 March 2009

Targeting the ischemic penumbra

scientific article published on 16 December 2010

Tear film inflammatory mediators during continuous wear of contact lenses and corneal refractive therapy

scientific article published on 13 June 2012

Temperature-Induced Changes in Reperfused Stroke: Inflammatory and Thrombolytic Biomarkers

scientific article published on 04 July 2020

Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke

scientific article published in January 2009

Temporal profile of molecular signatures associated with circulating endothelial progenitor cells in human ischemic stroke

scientific article published on 19 April 2012

The Increase of Circulating Endothelial Progenitor Cells After Acute Ischemic Stroke Is Associated With Good Outcome

scientific article published on 30 August 2007

The effect of simvastatin on the proteome of detergent-resistant membrane domains: decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate.

scientific article published in May 2010

The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke. ⬇️

scientific article

The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome

scientific article published on 21 December 2010

The role of angiogenesis in damage and recovery from ischemic stroke

scientific article published in June 2007

Toll-like receptors 2 and 4 in ischemic stroke: outcome and therapeutic values

scientific article

Toll-like receptors 7 and 8 expression is associated with poor outcome and greater inflammatory response in acute ischemic stroke

scientific article published on 26 February 2011

Trends in stroke outcomes in the last ten years in a European tertiary hospital

scientific article published on 03 October 2018

Usefulness of haptoglobin and serum amyloid A proteins as biomarkers for atherothrombotic ischemic stroke diagnosis confirmation

scientific article published on 30 December 2008

Vectorized nanodelivery systems for ischemic stroke: a concept and a need.

scientific article published on 11 April 2017

White matter injury restoration after stem cell administration in subcortical ischemic stroke

scientific article published on 19 June 2015

Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors

scientific article published on 7 November 2017

[18F]-FMISO PET/MRI Imaging Shows Ischemic Tissue around Hematoma in Intracerebral Hemorrhage

scientific article published on 13 November 2020

dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe

scientific article published in 2024

proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke.

scientific article published on August 2013

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