List of works by Daniel C. Liebler

A Reporter System for Translational Readthrough of Stop Codons in Human Cells

scientific article published on 17 April 2012

A bioinformatics workflow for variant peptide detection in shotgun proteomics

scientific article

Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer

scientific article in 2015

Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone

scientific article

Alkylation damage by lipid electrophiles targets functional protein systems

scientific article published on 15 January 2014

Alkylation of cytochrome c by (glutathion-S-yl)-1,4-benzoquinone and iodoacetamide demonstrates compound-dependent site specificity.

scientific article

Amended safety assessment of Hypericum perforatum-derived ingredients as used in cosmetics

scientific article

Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate

scientific article published on May 2011

Amended safety assessment of dodecylbenzenesulfonate, decylbenzenesulfonate, and tridecylbenzenesulfonate salts as used in cosmetics

scientific article

An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer.

scientific article

Analysis of protein adduction kinetics by quantitative mass spectrometry: competing adduction reactions of glutathione-S-transferase P1-1 with electrophiles ⬇️

scientific article

Antioxidant actions of beta-carotene in liposomal and microsomal membranes: role of carotenoid-membrane incorporation and alpha-tocopherol

scientific article published on 01 February 1997

Antioxidant chemistry of green tea catechins. Identification of products of the reaction of (-)-epigallocatechin gallate with peroxyl radicals

scientific article published on 01 April 1999

Antioxidant chemistry of green tea catechins. New oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin from their reactions with peroxyl radicals.

scientific article

Antioxidant reactions of vitamin E in the perfused rat liver: product distribution and effect of dietary vitamin E supplementation

scientific article published on 01 March 1997

Antioxidant stoichiometry and the oxidative fate of vitamin E in peroxyl radical scavenging reactions

scientific article published on 01 September 1995

Basophile: accurate fragment charge state prediction improves peptide identification rates

scientific article published on 08 March 2013

CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling

scientific article published on 20 January 2015

Characterization of benzoquinone-peptide adducts by electrospray mass spectrometry

scientific article published on 01 October 2000

Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer

scientific article

Comparative shotgun proteomics using spectral count data and quasi-likelihood modeling.

scientific article

Comparison of protein immunoprecipitation-multiple reaction monitoring with ELISA for assay of biomarker candidates in plasma.

scientific article

Connecting genomic alterations to cancer biology with proteomics: the NCI Clinical Proteomic Tumor Analysis Consortium

scientific article published on October 2013

Covalent adduction of human serum albumin by 4-hydroxy-2-nonenal: kinetic analysis of competing alkylation reactions.

scientific article published in September 2006

Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3

scientific article

Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients

scientific article published on 12 December 2014

Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation.

scientific article

Cytosolic and nuclear protein targets of thiol-reactive electrophiles

scientific article published on January 2006

DNA-protein cross-linking by 1,2,3,4-diepoxybutane.

scientific article

Depletion of abundant plasma proteins and limitations of plasma proteomics.

scientific article

Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in liquid chromatography-multiple reaction monitoring-MS (LC-MRM-MS)

scientific article (publication date: September 2013)

Determination of singlet oxygen-specific versus radical-mediated lipid peroxidation in photosensitized oxidation of lipid bilayers: effect of beta-carotene and alpha-tocopherol

scientific article published in October 1997

Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer.

scientific article

Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

scientific article

Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and Electrophilic Stress

scientific article

Effect of UVB on hydrolysis of alpha-tocopherol acetate to alpha-tocopherol in mouse skin

scientific article published on 01 August 1998

Elucidating mechanisms of drug-induced toxicity.

scientific article

Enzymatic activation of chemicals to toxic metabolites.

scientific article

Epoxide products of beta-carotene antioxidant reactions

scientific article published on 01 January 1992

Equivalence of protein inventories obtained from formalin-fixed paraffin-embedded and frozen tissue in multidimensional liquid chromatography-tandem mass spectrometry shotgun proteomic analysis.

scientific article published on 24 May 2009

Evaluation of strong cation exchange versus isoelectric focusing of peptides for multidimensional liquid chromatography-tandem mass spectrometry

scientific article published on December 2008

Final amended safety assessment of hydroquinone as used in cosmetics

scientific article

Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients

scientific article

Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of pelargonic acid (nonanoic acid) and nonanoate esters.

scientific article published on December 2011

Final report of the Cosmetic Ingredient Review Expert Panel safety assessment of polymethyl methacrylate (PMMA), methyl methacrylate crosspolymer, and methyl methacrylate/glycol dimethacrylate crosspolymer

scientific article published on May 2011

Final report of the safety assessment of Kojic acid as used in cosmetics

scientific article

Formation and identification of protein adducts to cytosolic proteins in guinea pig liver slices exposed to halothane

scientific article

Gas chromatography-mass spectrometry analysis of vitamin E and its oxidation products

scientific article published on 01 April 1996

Gas chromatography-mass spectrometry analysis of vitamin E and its oxidation products

scientific article published on 01 January 1999

GeLC-MRM quantitation of mutant KRAS oncoprotein in complex biological samples

scientific article

Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal

scientific article published on 02 December 2008

Global shifts in protein sumoylation in response to electrophile and oxidative stress.

scientific article

Global stability of plasma proteomes for mass spectrometry-based analyses.

scientific article

Global, in situ, site-specific analysis of protein S-sulfenylation

scientific article

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

scientific journal article

Hepatic injury and lipid peroxidation during hemorrhagic shock and resuscitation

scientific article published on 01 January 1993

Identification of Proteomic Features To Distinguish Benign Pulmonary Nodules from Lung Adenocarcinoma.

scientific article published on 21 July 2017

Identification of S-nitrosylation motifs by site-specific mapping of the S-nitrosocysteine proteome in human vascular smooth muscle cells

scholarly article

Identification of phosphorylation sites in glycine N-methyltransferase from rat liver

scientific article published on 7 March 2006

Identification of protein fragments as pattern features in MALDI-MS analyses of serum

scientific article

Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.

scientific article published on 31 January 2008

Identification of proteins adducted by lipid peroxidation products in plasma and modifications of apolipoprotein A1 with a novel biotinylated phospholipid probe.

scientific article published on 09 September 2008

Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane

scientific article published in December 2005

In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers.

scientific article

Increased protein nitration burden in the atherosclerotic lesions and plasma of apolipoprotein A-I deficient mice

scientific article published on 05 July 2007

Induction of redox instability of bovine myoglobin by adduction with 4-hydroxy-2-nonenal

scientific article published in April 2003

Inhibition of UVB induced DNA photodamage in mouse epidermis by topically applied alpha-tocopherol

scientific article published on 01 August 1997

Inhibition of protein phosphatase 2A activity by selective electrophile alkylation damage

scientific article published on August 2006

Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance.

scientific article

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels

scientific article

Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.

scientific article

Mapping protein modifications with liquid chromatography-mass spectrometry and the SALSA algorithm

scientific article

Mitochondrial protein targets of thiol-reactive electrophiles

scientific article published on 07 March 2008

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

scientific article

N-Terminal amino acid side-chain cleavage of chemically modified peptides in the gas phase: a mass spectrometry technique for N-terminus identification.

scientific article published on 19 June 2006

Network-assisted protein identification and data interpretation in shotgun proteomics

scientific article

Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein

Novel approaches to identify protein adducts produced by lipid peroxidation

scientific article

P-Mod: an algorithm and software to map modifications to peptide sequences using tandem MS data

scientific article

Painting a moving picture: large-scale proteomics efforts and their potential for changing patient care

scientific article published on 03 May 2011

Peptide sequence motif analysis of tandem MS data with the SALSA algorithm

scientific article

Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses

scientific article

Phospholipid-protein adducts of lipid peroxidation: synthesis and study of new biotinylated phosphatidylcholines.

scientific article published in February 2007

Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.

scientific article

Phosphotyrosine signaling analysis in human tumors is confounded by systemic ischemia-driven artifacts and intra-specimen heterogeneity

scientific article

Photoprotective actions of natural and synthetic melanins

scientific article published on 01 December 1998

Precision of multiple reaction monitoring mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue

scientific article

Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake

scientific article published on 01 March 1999

Products from reaction of peroxynitrite with gamma-tocopherol

scientific article published on 01 January 1999

Protein damage by reactive electrophiles: targets and consequences

scientific article

Protein identification using customized protein sequence databases derived from RNA-Seq data

scientific article

Protein targets of reactive electrophiles in human liver microsomes

scientific article published on 5 May 2007

Protein-based multiplex assays: mock presubmissions to the US Food and Drug Administration.

scientific article published on 10 December 2009

Protein-selective capture to analyze electrophile adduction of hsp90 by 4-hydroxynonenal.

scientific article

Proteogenomic analysis reveals unanticipated adaptations of colorectal tumor cells to deficiencies in DNA mismatch repair.

scientific article published on 18 November 2013

Proteogenomic characterization of human colon and rectal cancer

scientific article (publication date: 18 September 2014)

Proteomic analysis of colon and rectal carcinoma using standard and customized databases

scientific article published on 23 June 2015

Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.

scientific article

Proteomic characterization of metabolites, protein adducts, and biliary proteins in rats exposed to 1,1-dichloroethylene or diclofenac

scientific article published in October 2003

Proteomic consequences of a single gene mutation in a colorectal cancer model

scientific article

Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin

scientific article

Proteomics of lipid oxidation-induced oxidation of porcine and bovine oxymyoglobins

scientific article published on 01 February 2007

Proteomics: clinical applications for head and neck squamous cell carcinoma

scientific article

QuaMeter: multivendor performance metrics for LC-MS/MS proteomics instrumentation

scientific article published on 27 June 2012

Quantitative Profiling of Protein Tyrosine Kinases in Human Cancer Cell Lines by Multiplexed Parallel Reaction Monitoring Assays

scientific article published on 2 December 2015

Quantitative analysis by liquid chromatography-tandem mass spectrometry of deuterium-labeled and unlabeled vitamin E in biological samples.

scientific article

Quantitative analysis of modified proteins by LC-MS/MS of peptides labeled with phenyl isocyanate

scientific article

Quantitative chemoproteomics for site-specific analysis of protein alkylation by 4-hydroxy-2-nonenal in cells

scientific article published on 9 February 2015

RIFM fragrance ingredient safety assessment, (2E,6Z)-Nona-2,6-dien-1-ol, CAS registry number 28069-72-9.

scientific article published on 02 July 2015

RIFM fragrance ingredient safety assessment, (Z)-2-penten-1-ol, CAS Registry Number 1576-95-0.

scientific article published on 02 July 2015

RIFM fragrance ingredient safety assessment, 2,6-Dimethyl-5-heptenal, CAS Registry Number 106-72-9.

scientific article

RIFM fragrance ingredient safety assessment, 2-methyl-3-buten-2-ol, CAS Registry Number 115-18-4.

scientific article published on 20 July 2015

RIFM fragrance ingredient safety assessment, 4-methylbenzyl acetate, CAS Registry Number 2216-45-7.

scientific article published on 5 April 2016

RIFM fragrance ingredient safety assessment, Benzyl acetate, CAS Registry Number 140-11-4.

scientific article published on 17 July 2015

RIFM fragrance ingredient safety assessment, Benzyl alcohol, CAS Registry Number 100-51-6.

scientific article published on 10 September 2015

RIFM fragrance ingredient safety assessment, Benzyl propionate, CAS Registry Number 122-63-4.

scientific article published on 15 December 2015

RIFM fragrance ingredient safety assessment, Eugenol, CAS Registry Number 97-53-0.

scientific article published on 15 December 2015

RIFM fragrance ingredient safety assessment, Fenchyl alcohol, CAS registry number 1632-73-1.

scientific article published on 02 September 2015

RIFM fragrance ingredient safety assessment, Isoborneol, CAS Registry Number 124-76-5.

scientific article published on 17 August 2015

RIFM fragrance ingredient safety assessment, Linalool, CAS registry number 78-70-6.

scientific article

RIFM fragrance ingredient safety assessment, Linalyl acetate, CAS Registry Number 115-95-7.

scientific article

RIFM fragrance ingredient safety assessment, Linalyl hexanoate, CAS Registry Number 7779-23-9.

scientific article

RIFM fragrance ingredient safety assessment, Linalyl isovalerate, CAS Registry Number 1118-27-0.

scientific article published on 31 August 2015

RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5

scientific article published on 27 March 2015

RIFM fragrance ingredient safety assessment, allyl phenylacetate, CAS registry number 1797-74-6.

scientific article published on 25 March 2015

RIFM fragrance ingredient safety assessment, borneol, CAS registry number 507-70-0.

scientific article published on 15 April 2015

RIFM fragrance ingredient safety assessment, ethyl anthranilate, CAS registry number 87-25-2.

scientific article published on 25 March 2015

RIFM fragrance ingredient safety assessment, isoamyl salicylate, CAS registry number 87-20-7.

scientific article published on 26 September 2015

RIFM fragrance ingredient safety assessment, isoeugenol, CAS Registry Number 97-54-1.

scientific article published on 23 December 2015

RIFM fragrance ingredient safety assessment, isophytol, CAS Registry Number 505-32-8.

scientific article published on 25 June 2015

RIFM fragrance ingredient safety assessment, l-Borneol, CAS registry number 464-45-9.

scientific article published on 16 April 2015

RIFM fragrance ingredient safety assessment, l-linalool, CAS Registry Number 126-91-0.

scientific article published on 15 December 2015

RIFM fragrance ingredient safety assessment, linalyl isobutyrate, CAS registry number 78-35-3.

scientific article published on 27 September 2015

RIFM fragrance ingredient safety assessment, methyl dihydrojasmonate, CAS registry number 24851-98-7.

scientific article

RIFM fragrance ingredient safety assessment, p-Isopropylbenzyl acetate, CAS Registry Number 59230-57-8.

scientific article published on 5 April 2016

RIFM fragrance ingredient safety assessment, α-Irone, CAS registry number 79-69-6

scientific article published on 27 March 2015

RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde, CAS registry number 122-40-7.

scientific article

RIFM fragrance ingredient safety assessment, α-butylcinnamaldehyde, CAS Registry Number 7492-44-6.

scientific article published on 10 September 2015

RNA-seq data analysis at the gene and CDS levels provides a comprehensive view of transcriptome responses induced by 4-hydroxynonenal

scientific article

Reactions of Genistein with alkylperoxyl radicals

scientific article published on 01 July 2000

Reactions of peroxynitrite with gamma-tocopherol

scientific article published on 01 April 1997

Reactions of vitamin E and its model compound 2,2,5,7,8-pentamethylchroman-6-ol with ozone.

scientific article

Reactive oxidants from nitric oxide, oxidants and cellular signalling, and repair of oxidative DNA damage: a Chemical Pathology Study Section workshop

scientific article published on 01 August 1998

Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays

scientific article published on January 2016

Redox instability induced by 4-hydroxy-2-nonenal in porcine and bovine myoglobins at pH 5.6 and 4 degrees C

scientific article published on 01 May 2006

Relating protein adduction to gene expression changes: a systems approach

scientific article published on 19 May 2011

Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry

scientific article

Reproducibility of Differential Proteomic Technologies in CPTAC Fractionated Xenografts

scientific article published on 14 December 2015

Reversibility of covalent electrophile-protein adducts and chemical toxicity

scientific article

SALSA: a pattern recognition algorithm to detect electrophile-adducted peptides by automated evaluation of CID spectra in LC-MS-MS analyses

scientific article

Safety Assessment of Alkyl Ethylhexanoates as Used in Cosmetics.

scientific article

Safety Assessment of Boron Nitride as Used in Cosmetics

scientific article

Safety Assessment of Dialkyl Malates as Used in Cosmetics

scientific article published on July 2015

Safety Assessment of Ethanolamides as Used in Cosmetics

scientific article published on July 2015

Safety Assessment of Galactomannans as Used in Cosmetics.

scientific article published on July 2015

Safety Assessment of PEGylated oils as used in cosmetics

scientific article

Safety Assessment of Panax spp Root-Derived Ingredients as Used in Cosmetics

scientific article

Safety Assessment of Synthetic Fluorphlogopite as Used in Cosmetics

scientific article

Safety Assessment of Talc as Used in Cosmetics

scientific article published on July 2015

Safety assessment of 6-hydroxyindole as used in cosmetics

scientific article

Safety assessment of Tin(IV) oxide as used in cosmetics

scientific article

Safety assessment of Vitis vinifera (grape)-derived ingredients as used in cosmetics

scientific article

Safety assessment of alkyl benzoates as used in cosmetics

scientific article

Safety assessment of animal- and plant-derived amino acids as used in cosmetics.

scientific article

Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane

scientific article published on December 2011

Safety assessment of isoparaffins as used in cosmetics

scientific article

Safety assessment of modified terephthalate polymers as used in cosmetics

scientific article

Safety assessment of nylon as used in cosmetics

scientific article

Safety assessment of trimoniums as used in cosmetics

scientific article

Safety assessment of xylene sulfonic acid, toluene sulfonic acid, and alkyl aryl sulfonate hydrotropes as used in cosmetics

scientific article published on December 2011

Sample preparation and digestion for proteomic analyses using spin filters

scientific article

Selectively increased oxidative modifications mapped to detergent-insoluble forms of Abeta and beta-III tubulin in Alzheimer's disease

scientific article published in July 2006

Sequence mapping of epoxide adducts in human hemoglobin with LC-tandem MS and the SALSA algorithm

scientific article

Sequence tagging reveals unexpected modifications in toxicoproteomics

scientific article published on 7 January 2011

Site-specific mapping and quantification of protein S-sulphenylation in cells.

scientific article

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

scientific article published on 9 February 2010

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

scientific article published on 28 June 2005

Spin filter-based sample preparation for shotgun proteomics

scientific article published on 01 November 2009

Supporting tool suite for production proteomics

scientific article published on 29 September 2011

Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach

scientific article published on 17 January 2014

Targeted protein capture for analysis of electrophile-protein adducts.

scientific article published on January 2013

Targeted quantitation of proteins by mass spectrometry.

scientific article

The Expanding Landscape of the Thiol Redox Proteome

scientific article published on 30 October 2015

The development of selected reaction monitoring methods for targeted proteomics via empirical refinement.

scientific article published on April 2012

The poisons within: application of toxicity mechanisms to fundamental disease processes

scientific article

The role of metabolism in the antioxidant function of vitamin E.

scientific article published on January 1993

Tocopherone and expoxytocopherone products of vitamin E oxidation

scientific article published on 01 January 1994

UV-B-Induced photooxidation of vitamin E in mouse skin

scientific article published on 01 February 1999

UVB induced photooxidation of vitamin E

scientific article published on 01 February 1997

Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays

scientific article published on January 2016

Vitamin E oxidation in human atherosclerotic lesions

scientific article published in February 2002

alpha,beta-unsaturated aldehydes accelerate oxymyoglobin oxidation

scientific article published on 01 August 1999

alpha-tocopherol oxidation in beef and in bovine muscle microsomes

scientific article published on 01 April 1999

beta-carotene: friend or foe?

scientific article published on December 1997

proBAMsuite, a Bioinformatics Framework for Genome-Based Representation and Analysis of Proteomics Data

scientific article

Paulina is supported by:

About Paulina

Help