Search filters

List of works by Miguel Ángel Medina

(+)-Aeroplysinin-1 Modulates the Redox Balance of Endothelial Cells

scientific article published on 06 September 2018

(-)-Epigallocatechin-3-gallate interferes with mast cell adhesiveness, migration and its potential to recruit monocytes.

scientific article

4-methylumbelliferone inhibits angiogenesis in vitro and in vivo

scientific article published on 23 April 2013

5. Synthesis, metabolism and release of histamine

scientific article published on 01 April 2007

A combined model of hepatic polyamine and sulfur amino acid metabolism to analyze S-adenosyl methionine availability ⬇️

scientific article published on 04 August 2011

A comparative study of the effects of genistein and 2-methoxyestradiol on the proteolytic balance and tumour cell proliferation.

scientific article published on April 1999

A novel homogenous assay for topoisomerase II action and inhibition

scientific article published on 01 May 2005

A plasma membrane redox system in human retinoblastoma cells

scientific article published on 01 April 1993

A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation

scientific article published on 08 September 2020

A re-evaluation of fumagillin selectivity towards endothelial cells

scientific article published on September 2001

A re-evaluation of the mitogenic effect of serotonin on vascular endothelial cells

scientific article published on 01 January 2011

Advances in the Knowledge of the Molecular Biology of Glioblastoma and Its Impact in Patient Diagnosis, Stratification, and Treatment

scientific article published on 12 March 2020

Altered ornithine metabolism in tumor-bearing mice

scientific article published on 01 January 1989

An experiment on apoptosis induced by polyamine adducts produced in the presence of serum amine oxidase

scientific article published on 01 March 2000

An in vitro evaluation of the effects of homocysteine thiolactone on key steps of angiogenesis and tumor invasion.

scientific article published on November 2003

Analysis of Mammalian Histidine Decarboxylase Dimerization Interface Reveals an Electrostatic Hotspot Important for Catalytic Site Topology and Function

scientific article published on 13 May 2011

Anti-angiogenic effects of homocysteine on cultured endothelial cells

scientific article

Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary.

scientific article

Antiangiogenic activity of aeroplysinin-1, a brominated compound isolated from a marine sponge

scientific article

Ascorbic acid is cytotoxic for pediatric tumor cells cultured in vitro

scientific article published on 01 November 1994

Biogenic amines and polyamines: similar biochemistry for different physiological missions and biomedical applications

scientific article

Challenges of antiangiogenic cancer therapy: trials and errors, and renewed hope

scientific article published on May 2007

Characterization of plasma membrane redox activity from Ehrlich cells

scientific article published on 01 June 1994

Characterization of spermine uptake by Ehrlich tumour cells in culture.

scientific article published in January 2001

Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines

scientific article published on August 1995

Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives

scientific article published on 01 August 2018

Contribution by host tissues to circulating glutamine in mice inoculated with Ehrlich ascites tumor cells

scientific article published on 01 March 1988

Correction: Anti-Angiogenic and Anti-Inflammatory Properties of Kahweol, a Coffee Diterpene.

scientific article published in November 2011

Correction: Global Analysis of the Human Pathophenotypic Similarity Gene Network Merges Disease Module Components

scientific article published on 18 June 2013

DNA-chlorpheniramine interaction studied by spectroscopic techniques.

scientific article published in January 1998

DTD, an anti-inflammatory ditriazine, inhibits angiogenesis in vitro and in vivo

scientific article published on August 2008

Damnacanthal inhibits IgE receptor-mediated activation of mast cells

scientific article published on 2 February 2015

Damnacanthal, a noni anthraquinone, inhibits c-Met and is a potent antitumor compound against Hep G2 human hepatocellular carcinoma cells

scientific article published on 26 January 2015

Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties

scientific article published in 2023

Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein

scientific article published on 01 May 2000

Development of an expression macroarray for amine metabolism-related genes.

scientific article

Diamines interfere with the transport of L-ornithine in Ehrlich-cell plasma-membrane vesicles

scientific article published on December 1991

Dietary proteins and angiogenesis

scientific article

Dimethylfumarate inhibits angiogenesis in vitro and in vivo: a possible role for its antipsoriatic effect?

scientific article

Do not say ever never more: the ins and outs of antiangiogenic therapies

scientific article published on January 2010

Dual role of plasma membrane electron transport systems in defense

scientific article

ER stress increases StarD5 expression by stabilizing its mRNA and leads to relocalization of its protein from the nucleus to the membranes.

scientific article

Early systemic effects on the hepatic mitochondria of tumour bearing mice

scientific article published on 01 March 1989

Effect of palmitate, acetate and glucose on glutamine metabolism in Ehrlich ascites tumor cells

scientific article published on 01 June 1988

Effects of genistein and 2-methoxyestradiol on matrix metalloproteinases and their inhibitors secreted by Ehrlich ascites tumor cells

scientific article published on 01 May 2000

Effects of phorbol ester and dexamethasone treatment on histidine decarboxylase and ornithine decarboxylase in basophilic cells

scientific article published on May 2001

Effects of protein kinase C and phosphoprotein phosphatase modulators on Ehrlich cell plasma membrane redox system activity

scientific article published on 01 August 1996

Effects of ursolic acid on different steps of the angiogenic process

scientific article

Ehrlich cell plasma membrane redox system is modulated through signal transduction pathways involving cGMP and Ca2+ as second messengers

scientific article published on 01 December 1995

Epigallocatechin gallate reduces human monocyte mobility and adhesion in vitro

scientific article

Evaluation of the anti-angiogenic effect of aloe-emodin

scientific article published on December 2006

Evidence of an intracellular dissipative structure

scientific article published on 01 September 1988

Experimental evidence for structure-activity features in common between mammalian histidine decarboxylase and ornithine decarboxylase

scientific article

Exploring and challenging the network of angiogenesis.

scientific article published on 11 August 2011

Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner

scientific article published on 09 April 2020

First steps in computational systems biology: A practical session in metabolic modeling and simulation

scientific article published in May 2009

Fourier transform Raman study of the structural specificities on the interaction between DNA and biogenic polyamines

scientific article

Functional reconstitution of Ehrlich cell plasma membrane ferricyanide reductase

scientific article published on 01 December 1994

Genetic basis of hyperhomocysteinemia.

scientific article

Glucose Favors Lipid Anabolic Metabolism in the Invasive Breast Cancer Cell Line MDA-MB-231

scientific article published on 10 January 2020

Glutamine and glucose as energy substrates for Ehrlich ascites tumour cells

scientific article published on 01 February 1988

Glutamine transport by vesicles isolated from tumour-cell mitochondrial inner membrane

scientific article published on June 1995

Glycolysis and glutaminolysis in perifused Ehrlich ascites tumour cells

scientific article published on 01 January 1989

Green tea epigallocatechin-3-gallate is an inhibitor of mammalian histidine decarboxylase

scientific article published in August 2003

Histamine, polyamines, and cancer.

scientific article

Homocysteine inhibits the proliferation and invasive potential of HT-1080 human fibrosarcoma cells

scientific article published on February 2003

Homocysteine is a potent inhibitor of human tumor cell gelatinases

scientific article published in April 2003

Homocysteine is a potent modulator of plasma membrane electron transport systems.

scientific article published on 24 January 2008

Homocysteine: an emergent cardiovascular risk factor?

scientific article

Hyperforin, a bio-active compound of St. John's Wort, is a new inhibitor of angiogenesis targeting several key steps of the process

scientific article published on December 2005

Hyperhomocysteinemia and occlusive vascular disease: an emergent role for fibroblast growth factor 2.

scientific article published in April 2008

Hypericin in the dark inhibits key steps of angiogenesis in vitro

scientific article

IB05204, a dichloropyridodithienotriazine, inhibits angiogenesis in vitro and in vivo

scientific article published on 01 October 2007

Identification of a Zn(2+)-sensitive component of Ehrlich cell plasma membrane redox system by CHAPS-agarose-polyacrylamide electrophoresis and in situ staining of activity

scientific article published on 01 January 1997

In silico analysis of arginine catabolism as a source of nitric oxide or polyamines in endothelial cells

scientific article published on 23 May 2007

In vitro study of proteolytic degradation of rat histidine decarboxylase

scientific article published on 01 March 2000

Inorganic phosphate and energy charge compartmentation in Ehrlich ascites tumour cells in the presence of glucose and/or glutamine

scientific article published on 01 April 1988

Insights on the antitumor effects of kahweol on human breast cancer: decreased survival and increased production of reactive oxygen species and cytotoxicity

scientific article published on 13 April 2014

Interchange of amino acids between tumor and host

scientific article published on August 1, 1992

Involvement of essential histidine residue(s) in the activity of Ehrlich cell plasma membrane NADH-ferricyanide oxidoreductase

scientific article published on 01 February 1994

L-alanine transport by systems A and ASC in plasma membrane vesicles isolated from Ehrlich cells

scientific article published on 01 December 1991

L-glutamine transport in native vesicles isolated from Ehrlich ascites tumor cell membranes.

scientific article

Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability

scientific journal article

Malate-citrate cycle during glycolysis and glutaminolysis in Ehrlich ascites tumor cells

scientific article published on 01 May 1987

Mathematical modeling of polyamine metabolism in mammals.

scientific article

Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity

scientific article published on January 1995

Metabolic Reprogramming is a Hallmark of Metabolism Itself

scientific article published on 17 September 2020

Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic target

scientific article published on 22 May 2018

Methods for the determination of plasma total homocysteine: a review.

scientific article published in March 2000

Mitoxantrone toxicity on Ehrlich ascites tumour cells: inhibition of the transplasma membrane redox activity

scientific article published in April 1991

Mobilization of glutamine and asparagine in mouse kidney during Ehrlich cell carcinoma development

scientific article published on 01 July 1996

Modulation of the proteolytic balance plasminogen activator/plasminogen activator inhibitor by enhanced N-myc oncogene expression or application of genistein

scientific article published on October 1998

Monocyte chemoattractant protein-1: a key mediator in inflammatory processes.

scientific article published on 08 August 2008

Multifunctional plasma membrane redox systems

scientific article published on November 1997

Mutual effect of glucose and glutamine on their utilization by tumour cells

scientific article published on 01 January 1990

Na(+)-dependent AIB transport by neuroblastoma cells

scientific article published on December 1992

Nitrogen metabolism in tumor bearing mice

scientific article published on 01 February 1989

On the interpretation of Raman spectra of 1-aminooxy-spermine/DNA complexes.

scientific article published on 29 January 2004

Pharmacological potential of biogenic amine-polyamine interactions beyond neurotransmission.

scientific article published on September 2013

PhenUMA: a tool for integrating the biomedical relationships among genes and diseases.

scientific article

Phosphate-activated glutaminase expression during tumor development.

scientific article

Plasma membrane redox activity correlates with N-myc expression in neuroblastoma cells

scientific article published on 01 October 1992

Playing only one instrument may be not enough: limitations and future of the antiangiogenic treatment of cancer.

scientific article published on November 2007

Pleiotropic Role of Puupehenones in Biomedical Research.

scientific article published on 21 October 2017

Polyamine contents of human breast cancer cells treated with the cytotoxic agents chlorpheniramine and dehydrodidemnin B

scientific article published on 01 February 1997

Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells.

scientific article

Polyamine metabolism revisited

scientific journal article

Polyamines in mammalian pathophysiology

scientific article published on 21 June 2019

Polyamines: metabolism to systems biology and beyond.

scientific article published on 21 May 2007

Prognostic value of serum angiogenic activity in colorectal cancer patients.

scientific article

Protopia: a protein-protein interaction tool

scientific article

Purification and characterization of a plasma membrane ferricyanide-utilizing NADH dehydrogenase from Ehrlich tumour cells

scientific article published on March 1996

Purification of phosphate-dependent glutaminase from isolated mitochondria of Ehrlich ascites-tumour cells.

scientific article

Putrescine and chlorpheniramine inhibit Ehrlich ascites tumor cell plasma membrane ferricyanide reductase activity

scientific article published on 01 October 1998

Raman spectroscopy study of the interaction between biogenic polyamines and an alternating AT oligodeoxyribonucleotide

scientific article published in July 2003

Raman study of the interaction between polyamines and a GC oligonucleotide

scientific article published on July 2001

Rat histidine decarboxylase is a substrate for m-calpain in vitro

scientific article published on 01 May 2000

Real-time RT-PCR analysis of human histidine decarboxylase, a new marker for several types of leukemia and cancer.

scientific article published on January 2006

Regulatory cross-talk of mouse liver polyamine and methionine metabolic pathways: a systemic approach to its physiopathological consequences.

scientific article

Relevance of glutamine metabolism to tumor cell growth

scientific article

Roles of homocysteine in cell metabolism: old and new functions.

scientific article

Short-term effect of glutamine on the incorporation of glucose-carbon into nucleic acids in Ehrlich ascites tumour cells

scientific article published on 01 April 1990

Social pathway annotation: extensions of the systems biology metabolic modelling assistant

scientific article published on 21 October 2010

Sodium-dependent L-serine transport in plasma membrane vesicles isolated from Ehrlich cells by two-phase compartmentation

scientific article published on 01 September 1991

Spectroscopic analysis of recombinant rat histidine decarboxylase

scientific journal article

Structural perspective on the direct inhibition mechanism of EGCG on mammalian histidine decarboxylase and DOPA decarboxylase

scientific article published on 15 December 2011

Study of puupehenone and related compounds as inhibitors of angiogenesis

scientific article published on 01 May 2004

Subcellular distribution of adenine nucleotides in two Ehrlich cell lines metabolizing glucose

scientific article published on July 1990

Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol

scientific article published on 23 August 2019

Synthesis and antiangiogenic activity of new silybin galloyl esters

scientific article published on 03 October 2011

Systems biology for molecular life sciences and its impact in biomedicine ⬇️

scientific article published on August 19, 2012

Systems biology metabolic modeling assistant: an ontology-based tool for the integration of metabolic data in kinetic modeling.

scientific article

The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer

scientific article published on 31 August 2019

The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism

scientific article published on 15 January 2014

The anti-angiogenic 8-epipuupehedione behaves as a potential anti-leukaemic compound against HL-60 cells

scientific article published on April 2008

The antiangiogenic compound aeroplysinin-1 induces apoptosis in endothelial cells by activating the mitochondrial pathway.

scientific article

The brominated compound aeroplysinin-1 inhibits proliferation and the expression of key pro- inflammatory molecules in human endothelial and monocyte cells

scientific article

The marine fungal metabolite, AD0157, inhibits angiogenesis by targeting the Akt signaling pathway ⬇️

scientific article published on 16 January 2014

The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects

scientific article published on 2 November 2016

The pest regions containing C-termini of mammalian ornithine decarboxylase and histidine decarboxylase play different roles in protein degradation

scientific article published on 01 April 1999

The pursuit of creativity in biology

scientific article published on 01 December 2006

The role of fructose 2,6-bisphosphate in glycolytic oscillations in extracts and cells of Saccharomyces cerevisiae

scientific article published on 01 September 1990

The usefulness of post-genomics tools for characterization of the amine cross-talk in mammalian cells.

scientific article published on April 2007

Toluquinol, a marine fungus metabolite, is a new angiosuppresor that interferes with the Akt pathway.

scientific article published on 17 April 2013

Topology, tinkering and evolution of the human transcription factor network

scientific article published in December 2005

Transmembrane ferricyanide reductase activity in Ehrlich ascites tumor cells

scientific article published on 01 December 1988

Two phases of ferricyanide reductase activity in Ehrlich cell plasma membranes

scientific article published on 01 November 1992

What is known on angiogenesis-related rare diseases? A systematic review of literature.

scientific article published on December 2012

When metabolism meets topology: Reconciling metabolite and reaction networks

scientific article published in March 2010

kpath: integration of metabolic pathway linked data

scientific article (publication date: 2015)

Paulina is supported by:

About Paulina

Help