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List of works by Alexander J. Lazar

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

scientific article published in April 2018

A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.

scientific article published in March 2018

A Subgroup of Melanocytic Nevi on the Distal Lower Extremity (Ankle) Shares Features of Acral Nevi, Dysplastic Nevi, and Melanoma In Situ

scientific article published on 01 July 2007

A Window Into Clinical Next-Generation Sequencing-Based Oncology Testing Practices.

scientific article published on 13 October 2017

A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence

scientific article

A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours.

scientific article published on 13 August 2013

A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients

scientific article

A novel AKT3 mutation in melanoma tumours and cell lines

scientific article published on 23 September 2008

A randomized, phase II study of preoperative plus postoperative imatinib in GIST: evidence of rapid radiographic response and temporal induction of tumor cell apoptosis

scientific article

AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

scientific article published on 14 November 2015

Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors

scientific article

Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates

scientific article

Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor

scientific article

Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases

scientific article

American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine

scientific article published on 19 January 2016

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

scientific article published in April 2018

An erythematous plaque on the face

scientific article published on 24 October 2006

An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

scientific article

Analysis of Clinical and Molecular Factors Impacting Oncologic Outcomes in Undifferentiated Pleomorphic Sarcoma.

scientific article published on 3 February 2016

Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients

scientific article published on 28 March 2018

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

scientific article published on 14 June 2016

Analysis of prognostic factors impacting oncologic outcomes after neoadjuvant tyrosine kinase inhibitor therapy for gastrointestinal stromal tumors

scientific article

Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune checkpoint inhibition and radiotherapy

scientific article published on 31 October 2017

Analysis of αv integrin protein expression in human eyelid and periorbital squamous cell carcinomas

scientific article published on 06 March 2011

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

scientific article published on 15 June 2022

Angiogenesis-promoting gene patterns in alveolar soft part sarcoma

scientific article published on December 2007

Angiosarcoma: a tissue microarray study with diagnostic implications

scientific article published in June 2013

Angiosarcoma: clinical and molecular insights

scientific article published in June 2010

Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway

scientific article

Appropriate Use Criteria in Dermatopathology: Initial Recommendations from the American Society of Dermatopathology

scientific article published on 22 March 2018

Assessing inter-component heterogeneity of biphasic uterine carcinosarcomas

scientific article published on 05 September 2018

Association of intratumoral vascular endothelial growth factor expression and clinical outcome for patients with gastrointestinal stromal tumors treated with imatinib mesylate

scientific article published in November 2007

Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

scientific article published on 01 January 2019

Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 01 December 2018

Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors

scientific article published on 16 November 2010

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).

scientific article

B cells and tertiary lymphoid structures promote immunotherapy response

scientific article published on 15 January 2020

B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density

scientific article published on 26 February 2019

BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children

scientific article

BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma

scientific article published on 19 July 2012

Basal cell carcinoma with matrical differentiation: a case study with analysis of beta-catenin

scientific article published on March 2005

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma

scientific article

COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin.

scientific article

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

scientific article published on 31 July 2013

CTNNB1 genotyping and APC screening in pediatric desmoid tumors: a proposed algorithm

scientific article published on 28 February 2012

CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors

scientific article published on 21 February 2013

Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma?

article

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

scientific article published in April 2018

Cellular blue nevi of the eyelid: A possible diagnostic pitfall

scientific article published in February 2008

Challenges in next generation sequencing analysis of somatic mutations in transplant patients

scientific article published on 10 May 2018

Characteristic Ber-EP4 and EMA expression in sebaceoma is immunohistochemically distinct from basal cell carcinoma

scientific article

Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review

scientific article published on 05 March 2018

Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.

scientific article published on 5 March 2018

Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma

scientific article published on 02 December 2015

Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma

scientific article published on 6 August 2013

Clinical outcomes of molecularly confirmed clear cell sarcoma from a single institution and in comparison with data from the Surveillance, Epidemiology, and End Results registry

scientific article

Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma

scientific article published on 12 September 2012

Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation

scientific article published on 17 July 2013

Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial

scientific article published on 28 April 2016

Clinical, Pathological, and Molecular Variables Predictive of Malignant Peripheral Nerve Sheath Tumor Outcome

article

Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor

scientific article published on February 2008

Clinicopathologic considerations: how can we fine tune our approach to sarcoma?

scientific article published on October 2011

Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.

scientific article published on 10 August 2017

Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients

scientific article published on 2 December 2016

Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers.

scientific article published on 8 September 2017

Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma.

scientific article

Combined vascular endothelial growth factor receptor/epidermal growth factor receptor blockade with chemotherapy for treatment of local, uterine, and metastatic soft tissue sarcoma

scientific article published in September 2008

Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma

scientific article

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

scientific article published on 2 April 2018

Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab

scientific article published on 8 August 2017

Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing.

scientific article published on 14 December 2017

Complete Soft Tissue Sarcoma Resection is a Viable Treatment Option for Select Elderly Patients

scientific article published on 26 June 2009

Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations

scientific article

Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib

scientific article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

scientific article published in April 2018

Contemporary pathology of gastrointestinal stromal tumors

scientific article published in February 2009

Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type

scientific article

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

scientific article published on 03 January 2020

Corrigendum

scientific article published on 05 January 2018

Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma

scientific article

Cutaneous and subcutaneous metastases of gastrointestinal stromal tumors: a series of 5 cases with molecular analysis

scientific article published in May 2009

Cutaneous clear cell sarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 12 cases emphasizing its distinction from dermal melanoma

scientific article published in February 2010

Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations

scientific article published on December 2012

Cutaneous nodular fasciitis with genetic analysis: a case series

scientific article published on 30 September 2016

Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridiz

scientific article

Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity.

scientific article

Dermatofibrosarcoma protuberans with unusual sarcomatous transformation: a series of 4 cases with molecular confirmation

scientific article published in June 2011

Desmoid Tumor

article

Desmoid tumor: a disease opportune for molecular insights

scientific article published on January 2008

Desmoid tumor: from surgical extirpation to molecular dissection.

scientific article published on July 2009

Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts).

scientific article

Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma

article

Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay.

scientific article published on 25 June 2010

Diagnosis, management, and outcome of patients with dedifferentiated liposarcoma systemic metastasis

scientific article published on 26 May 2011

Diagnostic Value of TLE1 in Synovial Sarcoma: A Systematic Review and Meta-Analysis

scientific article published on 29 January 2020

Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas

scientific article published on 06 April 2014

Distinctive Dermal Clear Cell Mesenchymal Neoplasm: Clinicopathologic Analysis of Five Cases

article

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.

scientific article published in April 2018

Dual Roles of RNF2 in Melanoma Progression

scientific article

Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor

scientific article published on 5 May 2009

Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma

scientific article

ERG and FLI1 protein expression in epithelioid sarcoma

EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma

scientific article published on 23 June 2017

EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis

scientific article

Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma

scientific article

Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma.

scientific article

Epidermal growth factor receptor blockade in combination with conventional chemotherapy inhibits soft tissue sarcoma cell growth in vitro and in vivo

scientific article

Epidermodysplasia verruciformis in the setting of graft-versus-host disease

Epithelioid inflammatory myofibroblastic sarcoma: An aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK.

scientific article published in January 2011

Epithelioid sarcoma and unclassified sarcoma with epithelioid features: clinicopathological variables, molecular markers, and a new experimental model

scientific article published on 28 February 2011

Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.

scientific article published on 06 June 2016

Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma

scientific article

Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting.

scientific article published on 14 December 2015

Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological exami

scientific article published on 20 January 2016

Ewing's sarcoma: standard and experimental treatment options

scientific article published on April 2009

Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma.

scientific article

Exploiting antitumor immunity to overcome relapse and improve remission duration

scientific article

Expression of 'drugable' tyrosine kinase receptors in malignant peripheral nerve sheath tumour: potential molecular therapeutic targets for a chemoresistant cancer

scientific article published on July 2011

Expression of ERG, an Ets family transcription factor, distinguishes cutaneous angiosarcoma from histological mimics

Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma.

scientific article

Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy

scientific article published on 29 December 2012

Extensive survey of STAT6 expression in a large series of mesenchymal tumors

scientific article

Extraskeletal Osteosarcomas: A Case Made for Combined Modality Local Therapy With Radiation and Surgery

scientific article published on 01 March 2019

FAP-related desmoid tumors: a series of 44 patients evaluated in a cancer referral center

scientific article published on 01 May 2012

FUS rearrangements are rare in ‘pure’ sclerosing epithelioid fibrosarcoma

Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

scientific article published on 12 November 2018

Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma

Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma

scientific article

Galectin-3 Expression Is Associated with Tumor Progression and Pattern of Sun Exposure in Melanoma

scientific article published on 01 November 2006

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma.

scientific article

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

scientific article

Gene Expression Analysis Identifies Novel Targets for Cervical Cancer Therapy

article

Genetic aberrations in soft tissue leiomyosarcoma

scientific article published on 22 July 2008

Genetic aberrations of gastrointestinal stromal tumors

scientific article

Genetic alterations in signaling pathways in melanoma

scientific article

Genomic Classification of Cutaneous Melanoma

scientific article

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

scientific article published on 31 March 2018

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

scientific article

Genomic profiling of dedifferentiated liposarcoma compared to matched well-differentiated liposarcoma reveals higher genomic complexity and a common origin.

scientific article published on 2 April 2018

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

scientific article published in April 2018

Genomics, morphoproteomics, and treatment patterns of alveolar soft part sarcoma patients and response to multiple experimental therapies

scientific article published on 03 March 2020

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

scientific article published on 2 November 2017

Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas

scientific article published on 12 May 2013

High prevalence ofp53 exon 4 mutations in soft tissue sarcoma

scientific article published on 01 June 2007

High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth

scientific article published on 24 June 2017

High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma

scientific article published on 26 July 2011

Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations.

scientific article

Histopathologic Evaluation of Atypical Neurofibromatous Tumors and Their Transformation into Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis 1 Patients - A Consensus Overview.

scientific article published on 24 May 2017

Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors

scientific article published on 18 February 2015

How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments?

scientific article

Human sebaceous tumors harbor inactivating mutations in LEF1.

scientific article published on 26 March 2006

IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

scientific article

IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma

scientific article published on 30 August 2016

INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma

scientific article published on 26 July 2012

Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma

scientific article

Identification of preoperative factors associated with outcomes following surgical management of intra-abdominal recurrent or metastatic GIST following neoadjuvant tyrosine kinase inhibitor therapy

scientific article published on 15 February 2018

Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials

scientific article

Immuno-genomic landscape of osteosarcoma

scientific article published on 21 February 2020

Impact of sentinel lymphadenectomy on survival in a murine model of melanoma

article

Impact of surgical resection for subdiaphragmatic paragangliomas

scientific article published in March 2014

Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma

scientific article

Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target

scientific article

Increased vascular endothelial growth factor-C expression is insufficient to induce lymphatic metastasis in human soft-tissue sarcomas

scientific article published on 7 April 2009

Index report of cutaneous angiosarcomas with strong positivity for tyrosinase mimicking melanoma with further evaluation of melanocytic markers in a large angiosarcoma series

scientific article published on 27 May 2017

Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).

scientific article published on 16 December 2004

Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

scientific article published on December 2009

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

scientific article

Integrated proteomics and genomics analysis reveals a novel mesenchymal to epithelial reverting transition in leiomyosarcoma through regulation of slug

scientific article

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

scientific article published on August 2017

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

scientific article

Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors

scientific article

Introducing new College of American Pathologists reporting templates for cancer biomarkers

scientific article published on 28 June 2013

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

scientific article published on 21 October 2011

Kinetochore size variation in mammalian chromosomes: an image analysis study with evolutionary implications

scientific article published in February 1989

Liposarcoma in children and young adults: a multi-institutional experience

scientific article

Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations

scientific article published on 7 February 2013

Locoregional disease patterns in well-differentiated and dedifferentiated retroperitoneal liposarcoma: implications for the extent of resection?

scientific article published on 7 April 2014

Long-Term Outcomes for Patients With Desmoid Fibromatosis Treated With Radiation Therapy: A 10-Year Update and Re-evaluation of the Role of Radiation Therapy for Younger Patients

scientific article published on 12 December 2018

Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer

scientific article published on 06 December 2012

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

scientific article published on 01 September 2016

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival.

scientific article published on 18 March 2016

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

scientific article published on 8 December 2015

Lymphocyte Composition and Distribution in Inflammatory, Well-differentiated Retroperitoneal Liposarcoma

article

MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma

scientific article published on 15 May 2019

MRI may be used as a prognostic indicator in patients with extra-abdominal desmoid tumours

scientific article

MUC4 Is a Sensitive and Extremely Useful Marker for Sclerosing Epithelioid Fibrosarcoma

scientific article published on 01 October 2012

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

scientific article published in April 2018

Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways

scientific article published on 19 October 2009

Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor.

scientific article published on 24 December 2010

Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual

scientific article published on 13 October 2017

Merkel Cell Tumor in a Trichilemmal Cyst: Collision or Association?

article published in 2007

Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology

scientific article published on 26 March 2018

Mesenchymal to epithelial transition in sarcomas

scientific article

Metastasizing adenocarcinoma and multiple neoplastic proliferations arising in a nevus sebaceus

scientific article

Metastatic atypical fibroxanthoma: a series of 11 cases including with minimal and no subcutaneous involvement.

scientific article

Metastatic basal cell carcinoma exhibits reduced actin expression

scientific article

Metastatic hidradenocarcinoma with demonstration of Her-2/neu gene amplification by fluorescence in situ hybridization: potential treatment implications

article

MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling

scientific article

Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas

scientific article published on 10 November 2015

Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target

scientific article published in August 2008

Modeling Ewing sarcoma tumors in vitro with 3D scaffolds

scientific article published on April 2013

Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation

scientific article

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

scientific article published on 20 February 2019

Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker

scientific article published on 05 October 2020

Molecular approaches to resolve diagnostic dilemmas: the case of gastrointestinal stromal tumor and leiomyosarcoma

scientific article published on December 2007

Molecular characterization of epithelioid haemangioendotheliomas identifies novel WWTR1-CAMTA1 fusion variants

scientific article published on 14 May 2015

Molecular diagnosis of sarcomas: chromosomal translocations in sarcomas

scientific article published on August 2006

Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target

scientific article

Molecular profiling of sarcomas: new vistas for precision medicine.

scientific article published on 29 June 2017

Molecular prognosticators of complex karyotype soft tissue sarcoma outcome: a tissue microarray-based study

scientific article published on 29 October 2009

Muir-Torre syndrome appropriate use criteria: Effect of patient age on appropriate use scores

scientific article published on 26 April 2019

Multi-site desmoplastic small round cell tumors are genetically related and immune-cold

scientific article published on 04 April 2022

Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing.

scientific article

Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival

scientific article published on 05 June 2018

Myxofibrosarcoma.

scientific article

NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response.

scientific article published on 23 June 2017

NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma

scientific article

NRAS mutation status is an independent prognostic factor in metastatic melanoma

scientific article

NY-ESO-1 (CTAG1B) expression in mesenchymal tumors

scientific article published on 21 November 2014

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 8 October 2018

Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial

scientific article

Neoadjuvant treatment of soft-tissue sarcoma: a multimodality approach

scientific article published on March 2010

Nephrogenic fibrosing dermopathy with recurrence after allograft failure

article published in 2007

Nevoid melanoma

scientific article

New frontiers in the treatment of liposarcoma, a therapeutically resistant malignant cohort

scientific article published on 18 December 2010

New perspectives for staging and prognosis in soft tissue sarcoma

scientific article published on 3 June 2008

New strategies in melanoma: molecular testing in advanced disease

scientific article

New therapeutic targets in soft tissue sarcoma

scientific article

New, tolerable γ-secretase inhibitor takes desmoid down a notch

scientific article

Non-Radiographic Risk Factors Differentiating Atypical Lipomatous Tumors from Lipomas

scientific article published on 22 September 2016

Noncontact measurement of elasticity for the detection of soft-tissue tumors using phase-sensitive optical coherence tomography combined with a focused air-puff system

scientific article published on December 2012

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

scientific article

Novel systemic therapies in advanced liposarcoma: a review of recent clinical trial results

scientific article published on 10 May 2013

Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure

scientific article published on July 2015

Nuclear β-catenin localization and mutation of the CTNNB1 gene: a context-dependent association.

scientific article

Oncogenic Signaling Pathways in The Cancer Genome Atlas

scientific article published in April 2018

Optimizing Treatment of Desmoid Tumors

article

Oral-Cutaneous CD4-Positive T-cell Lymphoma: A Study of Two Patients

scientific article published on 01 February 2007

Outcome of Locally Recurrent and Metastatic Angiosarcoma

scientific article published on 24 June 2009

Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes

scientific article

PAX3/7-FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization

scientific article

PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms

scientific article published on 11 August 2016

PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation

scientific article published on 09 July 2018

PRKCI promotes immune suppression in ovarian cancer

scientific article published on 11 July 2017

Pan-cancer insights from The Cancer Genome Atlas: the pathologist's perspective

scientific article published on 30 December 2017

Papulo-vesicular eruption

scientific article published on 01 May 2007

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.

scientific article

Pathogenic Germline Variants in 10,389 Adult Cancers

scientific article published in April 2018

Pathology of gastrointestinal stromal tumors

scientific article

Patterns of recurrence and survival in sporadic, neurofibromatosis Type 1-associated, and radiation-associated malignant peripheral nerve sheath tumors

scientific article published on April 2016

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial

scientific article published on 4 October 2017

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

scientific article published in April 2018

Phase 1 adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma

scientific article published on 15 July 2015

Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma

scientific article

Phase II study of neoadjuvant checkpoint blockade in patients with surgically resectable undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma

scientific article published on 24 September 2018

Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects

scientific article (publication date: 13 October 1998)

Pilomatrix carcinomas contain mutations in CTNNB1, the gene encoding beta-catenin.

scientific article published in February 2005

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

scientific article published on 12 May 2020

Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related?

scientific article

Pleomorphic liposarcoma: clinical observations and molecular variables

scientific article

Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor.

scientific article published on 9 December 2015

Positive Tumor Response to Combined Checkpoint Inhibitors in a Patient With Refractory Alveolar Soft Part Sarcoma: A Case Report ⬇️

scientific article published on 06 July 2017

Primary Cutaneous Apocrine Carcinoma

Primary Synovial Sarcoma (SS) of the digestive system: a molecular and clinicopathological study of fifteen cases

scientific article

Primary chondro-osseous melanoma (chondrosarcomatous and osteosarcomatous melanoma).

scientific article published on 25 October 2017

Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases.

scientific article

Primary intracranial soft tissue sarcomas in children, adolescents, and young adults: single institution experience and review of the literature

scientific article published on 30 December 2015

Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases.

scientific article

Primitive Nonneural Granular Cell Tumors of Skin

scientific article published on 01 July 2005

Prognosis of T1 synovial sarcoma depends upon surgery by oncologic surgeons.

scientific article published on 24 May 2016

Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features

scientific article published on 05 August 2019

Progressive loss of myogenic differentiation in leiomyosarcoma has prognostic value

scientific article

Protocol for the examination of specimens from patients with gastrointestinal stromal tumor

scientific article published on 01 February 2010

Protocol for the examination of specimens from patients with tumors of soft tissue

scientific article published on 01 April 2010

Pseudocystic dermatofibrosarcoma protuberans: report of two cases and demonstration of COL1A1-PDGFB rearrangement

scientific article published on 01 March 2012

Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 01 December 2018

R132C IDH1 Mutations Are Found in Spindle Cell Hemangiomas and Not in Other Vascular Tumors or Malformations

RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway

scientific article

ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour

scientific article published on 17 February 2012

Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation

scientific article

Radiation-Associated Undifferentiated Pleomorphic Sarcoma is Associated with Worse Clinical Outcomes than Sporadic Lesions

scientific article

Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor.

scientific article published in December 2015

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

scientific article

Renal cell carcinoma marker (RCC-Ma) is specific for cutaneous metastasis of renal cell carcinoma

scientific article published on 01 May 2007

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

scientific article published on 12 May 2020

Retracted: Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

retracted article

Retroperitoneal undifferentiated pleomorphic sarcoma having microsatellite instability associated with Muir-Torre syndrome: case report and review of literature

scientific article published on 15 May 2013

Revealing retroperitoneal liposarcoma morphology using optical coherence tomography

Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model.

scientific article published on 21 July 2017

Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma

scientific article published on 18 May 2018

Role of chemotherapy in dedifferentiated liposarcoma of the retroperitoneum: defining the benefit and challenges of the standard

scientific article published on 19 September 2017

SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.

scientific article published on 16 October 2015

Sarcoma Brain Metastases: 28 Years of Experience at a Single Institution

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Sarcoma epidemiology and etiology: potential environmental and genetic factors

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Sarcoma metastases to the skin: a clinicopathologic study of 65 patients

scientific article published on 11 October 2011

Sarcoma molecular testing: diagnosis and prognosis.

scientific article published on July 2007

Sebaceous neoplasia and Torre-Muir syndrome.

scientific article

Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications.

scientific article

Sebaceous tumours contain a subpopulation of cells expressing the keratin 15 stem cell marker

scientific article published on 01 February 2007

Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in <i>Braf</i>-mutated melanoma

scientific article published on 06 November 2021

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

scientific article published on 04 January 2021

Site and Tumor Type Predicts DNA Mismatch Repair Status in Cutaneous Sebaceous Neoplasia

scientific article published on 01 June 2008

Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model

scientific article published on 11 May 2012

Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression

scientific article published on 20 January 2016

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.

scientific article

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma

scientific article published on 15 April 2020

Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors.

scientific article

Staging soft tissue sarcoma: evolution and change.

scientific article published on September 2006

Survivin is a viable target for the treatment of malignant peripheral nerve sheath tumors

scientific article published on 08 March 2012

Synovial Sarcoma of the Head and Neck: A Single Institution Review.

scientific article

Synovial Sarcoma: Advances in Diagnosis and Treatment Identification of New Biologic Targets to Improve Multimodal Therapy.

scientific article published on 10 April 2017

T-cell trafficking plays an essential role in tumor immunity

article

T-cell-rich angiomatoid polypoid pseudolymphoma of the skin: a clinicopathologic study of 17 cases and a proposed nomenclature

scientific article published on 24 February 2011

TERT promoter mutations in solitary fibrous tumour

scientific article published on 19 September 2018

TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo

scientific article

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations.

scientific article published on 13 April 2018

Targeted therapies for sarcomas: new roles for the pathologist

scientific article published on 02 December 2013

Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis.

scientific article published on 22 May 2017

Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors

scientific article

Targeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumors

scientific article

Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles

scientific article published on 15 March 2013

Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence

scientific article published on 30 March 2007

Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors

scientific article published on 2 March 2015

Template for Reporting Results of Biomarker Testing of Specimens From Patients With Melanoma

scientific article published on 4 September 2015

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Cancer Genomics Resource List 2014.

scientific article published on December 2014

The Immune Landscape of Cancer

scientific article published on 4 April 2018

The Importance of Lymphovascular Invasion in Uterine Adenosarcomas: Analysis of Clinical, Prognostic, and Treatment Outcomes

scientific article published on 01 September 2018

The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae

scientific article

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma

scientific article published on 31 May 2018

The Skin Allograft Revisited: A Potentially Permanent Wound Coverage Option in the Critically Ill Patient

scientific article published on 01 June 2009

The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma

scientific article published on 01 June 2022

The clinical behavior of well differentiated liposarcoma can be extremely variable: A retrospective cohort study at a major sarcoma center

scientific article published on 03 May 2018

The expression of c-Met pathway components in unclassified pleomorphic sarcoma/malignant fibrous histiocytoma (UPS/MFH): a tissue microarray study

scientific article published on September 2011

The genomic landscape of epithelioid sarcoma cell lines and tumours

scientific article published on 14 September 2015

The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma

scientific article published in June 2015

The long non-coding RNA NEAT1 promotes sarcoma metastasis by regulating RNA splicing pathways

scientific article published on 19 June 2020

The molecular pathology of sarcomas

scientific article published on 01 January 2010

The path to a better biomarker: Application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

scientific article published on 04 March 2020

The role of chemotherapy in advanced solitary fibrous tumors: a retrospective analysis

scientific article

The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours.

scientific article published on 19 December 2016

The usefulness of p63 detection for differentiating primary from metastatic skin adenocarcinomas

scientific article published on 01 September 2008

Three-dimensional computational analysis of optical coherence tomography images for the detection of soft tissue sarcomas

article

Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression

scientific article published on 21 January 2017

Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors

article published in 2012

Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma

scientific article published on 25 October 2018

USP6 activation in nodular fasciitis by promoter-swapping gene fusions.

scientific article published on 28 July 2017

Undifferentiated "round" cell ("Ewing-like") sarcoma: not always so-round nor Ewing-like

scientific article published on 13 February 2017

Unlucky number 13? Differential effects of KIT exon 13 mutation in gastrointestinal stromal tumors

scientific article published on 10 May 2008

Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance

scientific article published on 17 July 2012

Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations

scientific article

Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin

scientific article

Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: a single institution's experience

scientific article published on 20 January 2013

Uterine tumors with neuroectodermal differentiation: a series of 17 cases and review of the literature

scientific article published on February 2008

Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma

scientific article published on 6 May 2015

Validation of potential therapeutic targets in alveolar soft part sarcoma: an immunohistochemical study utilizing tissue microarray

Vimentin is a novel AKT1 target mediating motility and invasion

scientific article

Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults.

scientific article published on 14 July 2017

Wild-type p53 inhibits nuclear factor-kappaB-induced matrix metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and metastasis

scientific article published on 31 October 2006

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

scientific article

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

scientific article published on 01 February 2019

p53 staining correlates with tumor type and location in sebaceous neoplasms

scientific article published in April 2012

‘Difficult to diagnose’ desmoid tumours: a potential role forCTNNB1mutational analysis

article

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