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List of works by Simone Cenci

A new fluorogenic peptide determines proteasome activity in single cells.

scientific article published on October 2010

A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells

scientific article

Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ¹H HR-MAS NMR Metabolomics

scientific article published on 31 October 2016

Autophagy in Plasma Cell Ontogeny and Malignancy

scientific article published on 16 March 2016

Autophagy in plasma cell pathophysiology

scientific article

Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation

scientific article published in PLoS ONE

Autophagy, a new determinant of plasma cell differentiation and antibody responses

scientific article published on 11 March 2014

B lymphocytes inhibit human osteoclastogenesis by secretion of TGFbeta

scientific article

CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells

scientific article

Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells

scientific article

Dampening Ab responses using proteasome inhibitors following in vivo B cell activation

scientific article published in March 2008

Disease-relevant proteostasis regulation of cystic fibrosis transmembrane conductance regulator

scientific article published on 17 May 2013

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.

scientific article published on August 1999

Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha

scientific article

Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.

scientific article published on 15 August 2003

Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma.

scientific article published on 2 August 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hip Fracture in Nursing Homes: An Italian Study on Prevalence, Latency, Risk Factors, and Impact on Mobility

article

Iron increases the susceptibility of multiple myeloma cells to bortezomib.

scientific article published on 14 December 2012

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

scientific article

MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity

scientific article

Magnesium-enriched hydroxyapatite versus autologous bone in maxillary sinus grafting: combining histomorphometry with osteoblast gene expression profiles ex vivo

scientific article published in April 2009

Managing and exploiting stress in the antibody factory.

scientific article published on 24 April 2007

Metabolomics of B to plasma cell differentiation

scientific article published on 29 July 2011

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

scientific article published in 2021

Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors

scientific article

Plasma cells require autophagy for sustainable immunoglobulin production.

scientific article

Progressively impaired proteasomal capacity during terminal plasma cell differentiation

scientific article

Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis

scientific article published on 15 December 2017

Proteostenosis and plasma cell pathophysiology

scientific article published on 18 December 2010

Proteotoxic stress and cell lifespan control.

scientific article published on 23 July 2008

Recent advances and future directions in targeting the secretory apparatus in multiple myeloma

scientific article

Role of TNF-alpha producing T-cells in bone loss induced by estrogen deficiency

scientific article published on 01 April 2004

Short-term reproducibility of proximal femur bone mineral density in the elderly

scientific article published in October 1998

T Cell Activation Induces Human Osteoclast Formation via Receptor Activator of Nuclear Factor κB Ligand-Dependent and -Independent Mechanisms

scientific article published on 01 February 2001

The Proteasome in Terminal Plasma Cell Differentiation ⬇️

scientific article published on July 1, 2012

The amyloidogenic light chain is a stressor that sensitizes plasma cells to proteasome inhibitor toxicity.

scientific article

The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition.

scientific article published on 22 January 2009

The role of autophagy in plasma cell ontogenesis ⬇️

scientific article published on March 25, 2013

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling

scientific article published on 26 April 2016

Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo

scientific article

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