List of works - Guro Gafvelin

A hypoallergenic derivative of the major allergen of the dust mite Lepidoglyphus destructor, Lep d 2.6Cys, induces less IgE reactivity and cellular response in the skin than recombinant Lep d 2.

scientific article published on September 2001

A hypoallergenic peptide mix containing T cell epitopes of the clinically relevant house dust mite allergens

scientific article published on 03 October 2019

A mouse model for in vivo tracking of the major dust mite allergen Der p 2 after inhalation

scientific article published in July 2005

A novel adjuvant-allergen complex, CBP-rFel d 1, induces up-regulation of CD86 expression and enhances cytokine release by human dendritic cells in vitro.

scientific article

A proform of secretin with high secretin-like bioactivity

scientific article published on 01 May 1985

Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung.

scientific article

Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation

scientific article

Altered immunoregulatory profile during anti-tumour necrosis factor treatment of patients with inflammatory bowel disease

scientific article published in August 2012

Bypassing T cells using a B cell mimotope allergy vaccine

scientific article published in November 2009

Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy.

scientific article

Cloning and characterisation of two IgE-binding proteins, homologous to tropomyosin and alpha-tubulin, from the mite Lepidoglyphus destructor.

scientific article

Cloning of three new allergens from the dust mite Lepidoglyphus destructor using phage surface display technology

scientific article

Conjunctival provocation with airborne allergen in patients with atopic keratoconjunctivitis

article published in 2011

Covalent Coupling of Vitamin D3 to the Major Cat Allergen Fel d 1 Improves the Effects of Allergen-Specific Immunotherapy in a Mouse Model for Cat Allergy

article

Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens.

scientific article published in March 2001

Cytokine and Antibody Responses in Birch-Pollen-Allergic Patients Treated with Genetically Modified Derivatives of the Major Birch Pollen Allergen Bet v 1

article

Development of a mouse model for chronic cat allergen-induced asthma

scientific article published on 20 December 2014

Different sec-requirements for signal peptide cleavage and protein translocation in a model E. coli protein.

scientific article

Evaluation of Specific IgE to the Recombinant Group 2 Mite Allergens Lep d 2 and Tyr p 2 in the Pharmacia CAP System

scientific article published on 01 September 1999

Evaluation of safety and efficacy as an adjuvant for the chitosan-based vaccine delivery vehicle ViscoGel in a single-blind randomised Phase I/IIa clinical trial.

scientific article published on 16 September 2014

Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting.

scientific article published on 29 September 2004

Expression of two isoforms of Lep d 2, the major allergen of Lepidoglyphus destructor, in both prokaryotic and eukaryotic systems

scientific article

Hypoallergens for allergen-specific immunotherapy by directed molecular evolution of mite group 2 allergens

scientific article

Identification and characterisation of two allergens from the dust mite Acarus siro, homologous with fatty acid-binding proteins.

scientific article

IgG4 but no IgG1 antibody production after intralymphatic immunotherapy with recombinant MAT-Feld1 in human

scientific article published on 2 June 2016

Immune regulation by CD4+CD25+T cells and interleukin-10 in birch pollen-allergic patients and non-allergic controls

scientific article published on 01 August 2007

Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine

article

Lep d 2 polymorphisms in wild and culturedLepidoglyphus destructormites

scientific article published on 01 February 2003

Low Levels of Endotoxin Enhance Allergen-Stimulated Proliferation and Reduce the Threshold for Activation in Human Peripheral Blood Cells

Membrane protein anchors and polytopic determinants

scientific article published in November 1995

N-Tail translocation in a eukaryotic polytopic membrane protein. Synergy between neighboring transmembrane segments

article

Non-proteolytic aeroallergens from mites, cat and dog exert adjuvant-like activation of bronchial epithelial cells

scientific article published on 22 December 2010

Proline-induced disruption of a transmembrane alpha-helix in its natural environment.

scientific article published in December 1998

Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice.

scientific article published on 31 January 2009

Rational design of hypoallergens applied to the major cat allergen Fel d 1.

scientific article

Recombinant Bet v 1 vaccine for treatment of allergy to birch pollen.

scientific article published on December 2010

Rescue of thymocytes from cell death by vasoactive intestinal peptide

scientific article published in May 1995

SecA-dependence of the translocation of a large periplasmic loop in the Escherichia coli MalF inner membrane protein is a function of sequence context

SecA-independent translocation of the periplasmic N-terminal tail of an Escherichia coli inner membrane protein. Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation s

scientific article published in Journal of Biological Chemistry

Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics

Selenocysteine in proteins-properties and biotechnological use.

scientific article

Skin prick test and serological analysis with recombinant group 2 allergens of the dust mites L. destructor and T. putrescentiae

scientific article published in May 2000

Structural characterization of the tetrameric form of the major cat allergen Fel d 1

scientific article

T cell responses to recombinant isoforms, synthetic peptides and a mutant variant of Lep d 2, a major allergen from the dust mite Lepidoglyphus destructor

scientific article published in December 2001

The major cat allergen, Fel d 1, in diagnosis and therapy

scientific article published on 22 October 2009

The molecular basis of antigenic cross-reactivity between the group 2 mite allergens

scientific article published in June 2001

The non-proteolytic house dust mite allergen Der p 2 induce NF-kappaB and MAPK dependent activation of bronchial epithelial cells

scientific article

Topological "frustration" in multispanning E. coli inner membrane proteins.

scientific article published in May 1994

Topological rules for membrane protein assembly in eukaryotic cells

scientific article published in Journal of Biological Chemistry

Treatment with a Fel d 1 hypoallergen reduces allergic responses in a mouse model for cat allergy

article

Vaccination with genetically engineered allergens prevents progression of allergic disease.

scholarly article

[Biological engineering for new asthma therapy]

scientific article published on 01 June 2008

List of works by Guro Gafvelin

A hypoallergenic derivative of the major allergen of the dust mite Lepidoglyphus destructor, Lep d 2.6Cys, induces less IgE reactivity and cellular response in the skin than recombinant Lep d 2.

A hypoallergenic peptide mix containing T cell epitopes of the clinically relevant house dust mite allergens

A mouse model for in vivo tracking of the major dust mite allergen Der p 2 after inhalation

A novel adjuvant-allergen complex, CBP-rFel d 1, induces up-regulation of CD86 expression and enhances cytokine release by human dendritic cells in vitro.

A proform of secretin with high secretin-like bioactivity

Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung.

Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation

Altered immunoregulatory profile during anti-tumour necrosis factor treatment of patients with inflammatory bowel disease

Bypassing T cells using a B cell mimotope allergy vaccine

Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy.

Cloning and characterisation of two IgE-binding proteins, homologous to tropomyosin and alpha-tubulin, from the mite Lepidoglyphus destructor.

Cloning of three new allergens from the dust mite Lepidoglyphus destructor using phage surface display technology

Conjunctival provocation with airborne allergen in patients with atopic keratoconjunctivitis

Covalent Coupling of Vitamin D3 to the Major Cat Allergen Fel d 1 Improves the Effects of Allergen-Specific Immunotherapy in a Mouse Model for Cat Allergy

Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens.

Cytokine and Antibody Responses in Birch-Pollen-Allergic Patients Treated with Genetically Modified Derivatives of the Major Birch Pollen Allergen Bet v 1

Development of a mouse model for chronic cat allergen-induced asthma

Different sec-requirements for signal peptide cleavage and protein translocation in a model E. coli protein.

Evaluation of Specific IgE to the Recombinant Group 2 Mite Allergens Lep d 2 and Tyr p 2 in the Pharmacia CAP System

Evaluation of safety and efficacy as an adjuvant for the chitosan-based vaccine delivery vehicle ViscoGel in a single-blind randomised Phase I/IIa clinical trial.

Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting.

Expression of two isoforms of Lep d 2, the major allergen of Lepidoglyphus destructor, in both prokaryotic and eukaryotic systems

Hypoallergens for allergen-specific immunotherapy by directed molecular evolution of mite group 2 allergens

Identification and characterisation of two allergens from the dust mite Acarus siro, homologous with fatty acid-binding proteins.

IgG4 but no IgG1 antibody production after intralymphatic immunotherapy with recombinant MAT-Feld1 in human

Immune regulation by CD4+CD25+T cells and interleukin-10 in birch pollen-allergic patients and non-allergic controls

Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine

Lep d 2 polymorphisms in wild and culturedLepidoglyphus destructormites

Low Levels of Endotoxin Enhance Allergen-Stimulated Proliferation and Reduce the Threshold for Activation in Human Peripheral Blood Cells

Membrane protein anchors and polytopic determinants

N-Tail translocation in a eukaryotic polytopic membrane protein. Synergy between neighboring transmembrane segments

Non-proteolytic aeroallergens from mites, cat and dog exert adjuvant-like activation of bronchial epithelial cells

Proline-induced disruption of a transmembrane alpha-helix in its natural environment.

Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice.

Rational design of hypoallergens applied to the major cat allergen Fel d 1.

Recombinant Bet v 1 vaccine for treatment of allergy to birch pollen.

Rescue of thymocytes from cell death by vasoactive intestinal peptide

SecA-dependence of the translocation of a large periplasmic loop in the Escherichia coli MalF inner membrane protein is a function of sequence context

SecA-independent translocation of the periplasmic N-terminal tail of an Escherichia coli inner membrane protein. Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation s

Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics

Selenocysteine in proteins-properties and biotechnological use.

Skin prick test and serological analysis with recombinant group 2 allergens of the dust mites L. destructor and T. putrescentiae

Structural characterization of the tetrameric form of the major cat allergen Fel d 1

T cell responses to recombinant isoforms, synthetic peptides and a mutant variant of Lep d 2, a major allergen from the dust mite Lepidoglyphus destructor

The major cat allergen, Fel d 1, in diagnosis and therapy

The molecular basis of antigenic cross-reactivity between the group 2 mite allergens

The non-proteolytic house dust mite allergen Der p 2 induce NF-kappaB and MAPK dependent activation of bronchial epithelial cells

Topological "frustration" in multispanning E. coli inner membrane proteins.

Topological rules for membrane protein assembly in eukaryotic cells

Treatment with a Fel d 1 hypoallergen reduces allergic responses in a mouse model for cat allergy

Vaccination with genetically engineered allergens prevents progression of allergic disease.

[Biological engineering for new asthma therapy]