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List of works by Tracy Robson

A cytochrome P450 2B6 meditated gene therapy strategy to enhance the effects of radiation or cyclophosphamide when combined with the bioreductive drug AQ4N.

scientific article published in July 2005

A novel FK506-like binding protein interacts with the glucocorticoid receptor and regulates steroid receptor signaling

scientific article

A novel human stress response-related gene with a potential role in induced radioresistance

scientific article

Abstract 3288: The anti-tumour efficacy of the novel peptide inhibitor of angiogenesis ALM-201

Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study.

scientific article

BRCA1 and MAD2 Are Coexpressed and Are Prognostic Indicators in Tubo-ovarian High-Grade Serous Carcinoma.

scientific article published in March 2018

Bioreductive GDEPT using cytochrome P450 3A4 in combination with AQ4N.

scientific article published in January 2003

Cytochrome P450 1B1 expression in rat esophageal tumorigenesis promoted by gastric and duodenal reflux

scientific article published on 01 February 2009

Cytochrome P450 1B1 mRNA untranslated regions interact to inhibit protein translation

scientific article

DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system

scientific article published on 3 March 2018

DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles

scientific article published on 12 December 2016

DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen

scientific article published on 09 July 2019

Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program

scientific article published on 22 December 2015

Delivery of RALA/siFKBPL nanoparticles via electrospun bilayer nanofibres: An innovative angiogenic therapy for wound repair

scientific article published on 30 October 2019

Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

scientific article

Development of TMTP-1 targeted designer biopolymers for gene delivery to prostate cancer.

scientific article published on 20 January 2016

Differential effects on cell killing in metallothionein overexpressing CHO mutant cell lines

scientific article published on November 1990

Emerging Roles for von Willebrand Factor in Cancer Cell Biology

scientific article published on 17 November 2017

Evaluation of a multi-functional nanocarrier for targeted breast cancer iNOS gene therapy.

scientific article

Evaluation of a synthetic CArG promoter for nitric oxide synthase gene therapy of cancer

scientific article

Evaluation of the antiangiogenic potential of AQ4N.

scientific article published in March 2008

FK506 binding proteins and inflammation related signalling pathways; basic biology, current status and future prospects for pharmacological intervention

scientific article published on 02 July 2020

FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4

scientific article published on 11 April 2019

FKBPL and peptide derivatives: novel biological agents that inhibit angiogenesis by a CD44-dependent mechanism.

scientific article

FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis.

scientific article published on 12 March 2015

FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy

scientific article

FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer

scientific article published on 27 November 2019

FKBPL: a marker of good prognosis in breast cancer

scientific article published in May 2015

FKBPL: a novel prognostic and predictive biomarker?

scientific article published on 18 May 2010

Gamma irradiation and targeted radionuclides enhance the expression of the noradrenaline transporter transgene controlled by the radio-inducible p21(WAF1/CIP1) promoter

scientific article published on 21 January 2013

Gene regulation by low-dose ionizing radiation in a normal human lung epithelial cell line.

scientific article

Gene therapy via inducible nitric oxide synthase: a tool for the treatment of a diverse range of pathological conditions

scientific article published on August 2008

Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer.

scientific article

Gene-directed enzyme prodrug therapy: a current assessment.

scientific article published in August 2004

Guest Editorial

scientific article published on 01 September 2008

Human osteocalcin: a strong promoter for nitric oxide synthase gene therapy, with specificity for hormone refractory prostate cancer

scientific article published on June 2007

Hypersensitivity to very-low single radiation doses: its relationship to the adaptive response and induced radioresistance

scientific article

Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype

scientific article

Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen.

scientific article published on 5 August 2013

Identification of the inducible nitric oxide synthase gene in macro- and microvascular endothelial cell lines

scientific article published on February 1997

Increased DNA-repair capacity and the modulation of 2 proteins in and metallothionein overexpressing Chinese hamster cell line

scientific article published on March 1994

Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance

scientific article published on May 2000

Increased sensitivity of a Chinese hamster ovary cell line to alkylating agents after overexpression of the human metallothionein II-A gene

scientific article published on September 1992

Induction and rejoining of DNA double-strand breaks in bladder tumor cells

scientific article

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

scientific article published on 05 March 2021

Modification of vascular tone using iNOS under the control of a radiation-inducible promoter

scientific article published in July 2000

Molecular biology: the key to personalised treatment in radiation oncology?

scientific article published on September 2010

Nitric Oxide: Monotherapy or Sensitiser to Conventional Cancer Treatments?

article published in 2010

Nitric oxide in cancer therapeutics: interaction with cytotoxic chemotherapy

scientific article published on January 2010

Nitric oxide physiology and pathology

scientific article published on January 2011

Nitric oxide synthase gene therapy enhances the toxicity of cisplatin in cancer cells

scientific article

Nitric oxide synthase gene therapy: A potent therapeutic in metastatic breast cancer

article

Nitric oxide--a novel therapeutic for cancer.

scientific article published on 29 April 2008

Nitrosative stress as a mediator of apoptosis: implications for cancer therapy.

scientific article published on January 2010

Nitrosative stress in cancer therapy.

scientific article published on May 2007

Obesity and Cancer Metastasis: Molecular and Translational Perspectives

scientific article published on 16 December 2020

Overexpression of metallothionein in CHO cells and its effect on cell killing by ionizing radiation and alkylating agents

scientific article

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy.

scientific article published on 20 January 2016

Pericytes influence endothelial cell growth characteristics: role of plasminogen activator inhibitor type 1 (PAI-1).

scientific article published on 13 September 2005

Potential use of the alkaline comet assay as a predictor of bladder tumour response to radiation

scientific article

Potentiating the Anticancer Properties of Bisphosphonates by Nanocomplexation with the Cationic Amphipathic Peptide, RALA.

scientific article published on 08 March 2016

Prognostic Significance of Glucocorticoid Receptor Expression in Cancer: A Systematic Review and Meta-Analysis

scientific article published on 01 April 2021

RALA-mediated delivery of FKBPL nucleic acid therapeutics

scientific article published on 30 September 2015

Radiation and the genome: from risks to opportunities for therapeutic exploitation

scientific article published on 20 July 2010

Radiosensitization of colon cancer cell lines by docetaxel: mechanisms of action

scientific article

Rational design and characterisation of a linear cell penetrating peptide for non-viral gene delivery

scientific article published on 20 November 2020

Regulation ofFOSby Different Compartmental Stresses Induced by Low Levels of Ionizing Radiation

scientific article published on 01 November 2000

Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells

scientific article

Retinal Pericytes Control Expression of Nitric Oxide Synthase and Endothelin-1 in Microvascular Endothelial Cells

scientific article published on 01 January 2000

Role of a novel angiogenesis FKBPL-CD44 pathway in preeclampsia risk stratification and mesenchymal stem cell treatment

scientific article published on 03 July 2020

Role of the Hsp90 cochaperone, FKBPL, in oestrogen receptor signalling and breast cancer growth and survival

scientific article published on 13 May 2008

Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment.

scientific article published on 31 December 2016

Targeting cancer stem cells in the clinic: Current status and perspectives.

scientific article published on 5 February 2018

Targeting nitric oxide for cancer therapy.

scientific article published on January 2007

Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway

scientific article published on 5 June 2013

The Cancer Stem Cell Niche in Ovarian Cancer and Its Impact on Immune Surveillance

scientific article published on 15 April 2021

The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases.

scientific article published on 19 May 2015

The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway

scientific article

The contribution of N₂O₃ to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation

scientific article published on 28 March 2013

The effect of ultra violet B (TL-01) phototherapy on epidermal expression of p53 protein in psoriatic plaques

scientific article

The emerging role of FK506-binding proteins as cancer biomarkers: a focus on FKBPL.

scientific article published on April 2011

The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation

scientific article published on 7 February 2008

The therapeutic and diagnostic potential of FKBPL; a novel anticancer protein

scientific article published on 16 January 2012

The tissue plasminogen activator gene promoter: a novel tool for radiogenic gene therapy of the prostate?

scientific article

Themed Issue: Radiation biology - can new concepts achieve better treatment outcomes?

scholarly article by Tracy Robson & David G Hirst published August 2008 in Journal of Pharmacy and Pharmacology

Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives

scientific article published on 20 June 2020

Transcending epithelial and intracellular biological barriers; a prototype DNA delivery device

scientific article published on 13 February 2016

Transcriptional Targeting in Cancer Gene Therapy

scientific article

Transcriptional regulation of inducible nitric oxide synthase gene therapy: targeting early stage and advanced prostate cancer

scientific article published in September 2010

Tumor-selective drug activation: a GDEPT approach utilizing cytochrome P450 1A1 and AQ4N.

scientific article published on June 2006

Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: a novel suicide gene therapy

scientific article

Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment

scientific article published in June 2004

Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?

scientific article published on 29 September 2009

Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself.

scientific article

p21((WAF1))-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy.

scientific article published on 28 September 2006

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