List of works - Søren E. Degn

Assay interference caused by antibodies reacting with rat kappa light-chain in human sera

scientific article published on 12 July 2011

B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation

scientific article published on 06 December 2021

B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo

scientific article

Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system

scientific article

Capturing change in clonal composition amongst single mouse germinal centers

article

Clonal Evolution of Autoreactive Germinal Centers

scientific article published on August 2017

Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.

scientific article published on 19 June 2013

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

scientific article

Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

scientific article

Disease-causing mutations in genes of the complement system

scientific article published on June 2011

Endogenous Natural Complement Inhibitor Regulates Cardiac Development

scientific article published on 3 March 2017

Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

scientific article published on 01 November 2019

Humoral pattern recognition and the complement system.

scientific article

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

scientific article published on 11 April 2019

MAp19, the alternative splice product of the MASP2 gene.

scientific article published on 17 August 2011

MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation

scientific article

Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components

scientific article published in July 2012

Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function

scientific article published on 10 September 2012

Mitochondria and the lectin pathway of complement

scientific article published on February 2013

Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity

scientific article

Recombinant expression of the autocatalytic complement protease MASP-1 is crucially dependent on co-expression with its inhibitor, C1 inhibitor

scientific article published on 11 January 2013

Response to comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function"

Targeting autoreactive germinal centers to curb autoimmunity

scientific article

The lectin pathway and its implications in coagulation, infections and auto-immunity

scientific article published on February 2011

List of works by Søren E. Degn

Assay interference caused by antibodies reacting with rat kappa light-chain in human sera

B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation

B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo

Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system

Capturing change in clonal composition amongst single mouse germinal centers

Clonal Evolution of Autoreactive Germinal Centers

Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

Disease-causing mutations in genes of the complement system

Endogenous Natural Complement Inhibitor Regulates Cardiac Development

Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

Humoral pattern recognition and the complement system.

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

MAp19, the alternative splice product of the MASP2 gene.

MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation

Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components

Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function

Mitochondria and the lectin pathway of complement

Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity

Recombinant expression of the autocatalytic complement protease MASP-1 is crucially dependent on co-expression with its inhibitor, C1 inhibitor

Response to comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function"

Targeting autoreactive germinal centers to curb autoimmunity

The lectin pathway and its implications in coagulation, infections and auto-immunity

The pro-factor D cleaving activity of MASP-1/-3 is not required for alternative pathway function