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List of works by Rajiv Khanna

A new approach for cellular immunotherapy of nasopharyngeal carcinoma

scientific article published on November 2012

Acquisition of polyfunctionality by Epstein-Barr virus-specific CD8+ T cells correlates with increased resistance to galectin-1-mediated suppression

scientific article published on 08 April 2009

Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease.

scientific article published on August 1999

Ad-gBCMVpoly: A novel chimeric vaccine strategy for human cytomegalovirus-associated diseases

scientific article

Adoptive T-cell therapy for pediatric cytomegalovirus-associated retinitis

scientific article published on 01 June 2019

Adoptive cellular immunotherapy for virus-associated cancers: a new paradigm in personalized medicine.

scientific article published on 21 December 2016

Adoptive therapy for EBV-induced cancers: driving success with post-transplant lymphoproliferative disorder to other EBV-derived tumors

scientific article published on June 2015

Advances in direct T-cell alloreactivity: function, avidity, biophysics and structure

scientific article published on 07 December 2011

Allelic polymorphism in the T cell receptor and its impact on immune responses

scientific article

Asymptomatic primary Epstein-Barr virus infection occurs in the absence of blood T-cell repertoire perturbations despite high levels of systemic viral load

scientific article published in December 2001

Autologous Adoptive T-cell Therapy for Recurrent or Drug-resistant Cytomegalovirus Complications in Solid Organ Transplant Recipients: A Single-arm Open-label Phase I Clinical Trial

scientific article published on 01 February 2019

Autologous T-cell therapy for cytomegalovirus as a consolidative treatment for recurrent glioblastoma.

scientific article published on 4 May 2014

Autophagy and proteasome interconnect to coordinate cross-presentation through MHC class I pathway in B cells

scientific article published on 14 June 2016

Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway

scientific article published on 21 June 2012

BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies.

scientific article published on April 2017

CD4+ T cells specific for glycoprotein B from cytomegalovirus exhibit extreme conservation of T-cell receptor usage between different individuals

scientific article published on 06 November 2007

CD8<sup>+</sup> T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses

scientific article published on 13 April 2021

Cellular immunotherapy directed against human cytomegalovirus as a novel approach for glioblastoma treatment

scientific article published on 25 June 2014

Checkpoint Immunotherapy: Picking a Winner.

scientific article published on August 2016

Clinical assessment of anti-viral CD8+ T cell immune monitoring using QuantiFERON-CMV® assay to identify high risk allogeneic hematopoietic stem cell transplant patients with CMV infection complications

scientific article published on 11 October 2013

Coinfection with Human Cytomegalovirus Genetic Variants in Transplant Recipients and Its Impact on Antiviral T Cell Immune Reconstitution

scientific article published on 8 June 2016

Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs.

scientific article

Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.

scientific article published on February 1998

Contemporaneous fluctuations in T cell responses to persistent herpes virus infections

scientific article published in January 2005

Contrasting Epstein-Barr virus-specific cytotoxic T cell responses to HLA A2-restricted epitopes in humans and HLA transgenic mice: implications for vaccine design

scientific article published in June 2001

Cross-reactive memory T cells for Epstein-Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major histocompatibility complex-bound peptide by T cells and its role in alloreactivity

scientific article published on July 1997

Cross-reactive recognition of human and primate cytomegalovirus sequences by human CD4 cytotoxic T lymphocytes specific for glycoprotein B and H.

scientific article published on November 2004

Cross-recognition of HLA DR4 alloantigen by virus-specific CD8+ T cells: a new paradigm for self-/nonself-recognition.

scientific article

Cross-recognition of human alloantigen by cytomegalovirus glycoprotein-specific CD4+ cytotoxic T lymphocytes: implications for graft-versus-host disease

scientific article

Crossreactive recognition of viral, self, and bacterial peptide ligands by human class I-restricted cytotoxic T lymphocyte clonotypes: implications for molecular mimicry in autoimmune disease

scientific article published on March 1999

Current understanding of the role of Epstein-Barr virus in lymphomagenesis and therapeutic approaches to EBV-associated lymphomas

scientific article published on January 2008

Cytokine-Mediated Loss of Blood Dendritic Cells During Epstein-Barr Virus-Associated Acute Infectious Mononucleosis: Implication for Immune Dysregulation

scientific article

Cytomegalovirus as a novel target for immunotherapy of glioblastoma multiforme

scientific article

Cytotoxic T cell recognition of allelic variants of HLA B35 bound to an Epstein-Barr virus epitope: influence of peptide conformation and TCR-peptide interaction

scientific article published in May 1999

Delineating the role of CD4+ T cells in the activation of human cytomegalovirus-specific immune responses following immunization with Ad-gBCMVpoly vaccine: implications for vaccination of immunocompromised individuals

scientific article published in September 2010

Determining virological, serological and immunological parameters of EBV infection in the development of PTLD

scientific article published on 24 May 2004

Differential outcome of IL-2/anti-IL-2 complex therapy on effector and memory CD8+ T cells following vaccination with an adenoviral vector encoding EBV epitopes

scientific article published on 11 April 2011

Discerning regulation of cis- and trans-presentation of CD8+ T-cell epitopes by EBV-encoded oncogene LMP-1 through self-aggregation

scientific article published on 16 April 2009

EBV and memory B cells: an affair with consequences

scientific article published on December 2015

Effective Treatment of Metastatic Forms of Epstein-Barr Virus–Associated Nasopharyngeal Carcinoma with a Novel Adenovirus-Based Adoptive Immunotherapy ⬇️

scientific article published on January 26, 2012

Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells

scientific article published on 31 August 2012

Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients

scientific article published on 01 March 2018

Epstein-Barr virus T-cell immunity despite rituximab.

scientific article published in February 2007

Epstein-Barr virus and advanced chronic lymphocytic leukemia: innocent until proven guilty?

scientific article published in May 2006

Epstein-Barr virus associated modulation of Wnt pathway is not dependent on latent membrane protein-1.

scientific article

Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products.

scientific article published on 25 October 2008

Epstein-Barr virus isolates with the major HLA B35.01-restricted cytotoxic T lymphocyte epitope are prevalent in a highly B35.01-positive African population

scientific article published on January 1995

Epstein-Barr virus-associated Hodgkin's lymphoma.

scientific article

Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis

scientific article published on 15 November 2018

Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis

scientific article published on 3 February 2014

Epstein-Barr virus-specific adoptive immunotherapy: a new horizon for multiple sclerosis treatment?

scientific article published in January 2014

Estimating cytomegalovirus growth rates by using only a single point

scientific article published on 9 January 2013

Ex vivo analysis of T-cell responses to Epstein-Barr virus-encoded oncogene latent membrane protein 1 reveals highly conserved epitope sequences in virus isolates from diverse geographic regions.

scientific article

Ex vivo expansion of human cytomegalovirus-specific cytotoxic T cells by recombinant polyepitope: implications for HCMV immunotherapy.

scientific article published on March 2005

Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme.

scientific article

Ex vivo monitoring of human cytomegalovirus-specific CD8+ T-cell responses using QuantiFERON-CMV.

scientific article

Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.

scientific article

Expression of LAG-3 by tumor-infiltrating lymphocytes is coincident with the suppression of latent membrane antigen-specific CD8+ T-cell function in Hodgkin lymphoma patients.

scientific article

G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation

scientific article

Galectin-1 is associated with poor prognosis in patients with cutaneous head and neck cancer with perineural spread

scientific article

Galectin-1 mediated suppression of Epstein-Barr virus specific T-cell immunity in classic Hodgkin lymphoma.

scientific article

Generation of cytotoxic T lymphocytes for immunotherapy of EBV-associated malignancies

scientific article published on January 2010

HLA peptide length preferences control CD8+ T cell responses

scientific article

HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading.

scientific article published in May 1998

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

scientific article

Herpesvirus vaccines: challenges and future prospects

scientific article published on December 2010

Host immune system strikes back: autophagy-mediated antigen presentation bypasses viral blockade of the classic MHC class I processing pathway

scientific article published on 29 August 2012

Hsp90 inhibitors block outgrowth of EBV-infected malignant cells in vitro and in vivo through an EBNA1-dependent mechanism.

scientific article

Human cytomegalovirus vaccine: time to look for alternative options.

scientific article

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments.

scientific article

Human immunology: a case for the ascent of non‐furry immunology ⬇️

scientific article published on 01 March 2011

Identification of cytotoxic T cell epitopes within Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1): evidence for HLA A2 supertype-restricted immune recognition of EBV-infected cells by LMP1-specific cytotoxic T lymphocytes

scientific article published in February 1998

Immune Regulation of Human Herpesviruses and Its Implications for Human Transplantation ⬇️

scientific article published on February 1, 2013

Immune monitoring of infectious complications in transplant patients: An important step towards improved clinical management

scientific article published on 17 January 2018

Immune-based therapeutic approaches to virus-associated cancers

scientific article published on 18 September 2018

Immunobiology of human cytomegalovirus: from bench to bedside.

scientific article published on January 2009

Immunotherapeutic strategies for EBV-associated malignancies.

scientific article published in June 2001

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

scientific article

Impaired Epstein-Barr Virus-Specific Neutralizing Antibody Response during Acute Infectious Mononucleosis Is Coincident with Global B-Cell Dysfunction

scientific article published on 24 June 2015

Induction of innate immune signatures following polyepitope protein-glycoprotein B-TLR4&9 agonist immunization generates multifunctional CMV-specific cellular and humoral immunity

scientific article published on 24 January 2014

Induction of pluripotent protective immunity following immunisation with a chimeric vaccine against human cytomegalovirus

scientific article published in 2008

Induction of therapeutic T-cell responses to subdominant tumor-associated viral oncogene after immunization with replication-incompetent polyepitope adenovirus vaccine

scientific article published on February 2004

Isolation of cytotoxic T lymphocytes from healthy seropositive individuals specific for peptide epitopes from Epstein-Barr virus nuclear antigen 1: implications for viral persistence and tumor surveillance

scientific article

Longitudinal dynamics of antigen-specific CD8+ cytotoxic T lymphocytes following primary Epstein-Barr virus infection

scientific article published in October 2001

Major histocompatibility complex: from genes to function

scientific article published on 01 April 1999

Messenger RNA sequence rather than protein sequence determines the level of self-synthesis and antigen presentation of the EBV-encoded antigen, EBNA1.

scientific article

Molecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell Repertoire

scientific article published on 10 February 2014

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP ⬇️

scientific article published on November 1, 2011

Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

scientific article

Narrowing of T-cell receptor beta variable repertoire during symptomatic herpesvirus infection in transplant patients.

scientific article published on 6 October 2009

Nasopharyngeal carcinoma-associated Epstein-Barr virus-encoded oncogene latent membrane protein 1 potentiates regulatory T-cell function.

scientific article published on 20 March 2007

Novel autologous T-cell therapy for drug-resistant cytomegalovirus disease after lung transplantation

scientific article published on 07 January 2016

Phenotypic and transcriptional profile correlates with functional plasticity of antigen-specific CD4+ T cells.

scientific article published on 3 December 2013

Plasma Epstein-Barr virus (EBV) DNA is a biomarker for EBV-positive Hodgkin's lymphoma.

scientific article

Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response

scientific article published on 04 January 2017

Preferential binding of unusually long peptides to MHC class I and its influence on the selection of target peptides for T cell recognition

scientific article published on 5 November 2007

Presentation of endogenous viral peptide epitopes by anti-CD40 stimulated human B cells following recombinant vaccinia infection.

scientific article published in August 1993

Prophylactic and therapeutic adenoviral vector-based multivirus-specific T-cell immunotherapy for transplant patients.

scientific article published on 24 August 2016

Proteasomal targeting of a viral oncogene abrogates oncogenic phenotype and enhances immunogenicity

scientific article published on 14 August 2003

Proteome-wide analysis of T-cell response to BK polyomavirus in healthy virus carriers and kidney transplant recipients reveals a unique transcriptional and functional profile

scientific article published on 14 January 2020

Recent Advances on the Possible Neuroprotective Activities of Epstein-Barr Virus Oncogene BARF1 Protein in Chronic Inflammatory Disorders of Central Nervous System

scientific article published on September 2010

Recent advances in designing an effective vaccine to prevent cytomegalovirus-associated clinical diseases ⬇️

scientific article published on June 1, 2013

Recombinant glycoprotein B vaccine formulation with Toll-like receptor 9 agonist and immune-stimulating complex induces specific immunity against multiple strains of cytomegalovirus

scientific article published on 9 February 2011

Reconstitution of the latent T-lymphocyte response to Epstein-Barr virus is coincident with long-term recovery from posttransplant lymphoma after adoptive immunotherapy

scientific article published in May 2003

Recruitment during infectious mononucleosis of CD3+CD4+CD8+ virus-specific cytotoxic T cells which recognise Epstein-Barr virus lytic antigen BHRF1.

scientific article published in May 1996

Regulation of protein translation through mRNA structure influences MHC class I loading and T cell recognition.

scholarly article

RelB nuclear translocation mediated by C-terminal activator regions of Epstein-Barr virus-encoded latent membrane protein 1 and its effect on antigen-presenting function in B cells

scientific article published on February 2002

Role of LMP1 in immune control of EBV infection.

scientific article

Selection pressure-driven evolution of the Epstein-Barr virus-encoded oncogene LMP1 in virus isolates from Southeast Asia

scientific article published on July 2004

Successful immunotherapy of HCMV disease using virus-specific T cells expanded from an allogeneic stem cell transplant recipient.

scientific article

T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen

scientific article

Targeting Epstein-Barr virus nuclear antigen 1 (EBNA1) through the class II pathway restores immune recognition by EBNA1-specific cytotoxic T lymphocytes: evidence for HLA-DM-independent processing

scientific article published on October 1997

Targeting of EBNA1 for rapid intracellular degradation overrides the inhibitory effects of the Gly-Ala repeat domain and restores CD8+ T cell recognition.

scientific article

The Development of Prophylactic and Therapeutic EBV Vaccines

scientific article published on January 2015

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

article

The impact of a large and frequent deletion in the human TCR β locus on antiviral immunity

scientific article

The influence of antiviral T-cell responses on the alloreactive repertoire.

scientific article

The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length

article

The role of cytotoxic T lymphocytes in the evolution of genetically stable viruses

scientific article published on February 1997

Therapeutic LMP1 polyepitope vaccine for EBV-associated Hodgkin disease and nasopharyngeal carcinoma

scientific article published on 05 December 2002

Transduction of primary lymphocytes with Epstein-Barr virus (EBV) latent membrane protein-specific T-cell receptor induces lysis of virus-infected cells: A novel strategy for the treatment of Hodgkin's disease and nasopharyngeal carcinoma

scientific article published on January 2006

Translation efficiency of EBNA1 encoded by lymphocryptoviruses influences endogenous presentation of CD8+ T cell epitopes

scientific article published in February 2007

Tumour surveillance: Missing peptides and MHC molecules ⬇️

scientific article published on February 1, 1998

Understanding human T‐cell‐mediated immunoregulation through herpesviruses ⬇️

scientific article published on 08 February 2011

Use of recombinant vaccinia to restimulate antigen specific human peripheral blood cytotoxic T lymphocytes

scientific article published on 01 April 1997

Vaccine strategies against human cytomegalovirus infection.

scientific article published on June 2007

Viruses and lymphoma.

scientific article

mRNA Structural constraints on EBNA1 synthesis impact on in vivo antigen presentation and early priming of CD8+ T cells

scientific article

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