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List of works by John Pearson

2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung

scientific article

A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding

scientific article published on June 2016

A New Zealand platform to enable genetic investigation of adverse drug reactions

scientific article published in December 2017

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A multiplex pharmacogenetics assay using the MinION nanopore sequencing device

scientific article published on 01 November 2019

A novel pathway for investigation of colorectal symptoms with colonoscopy or computed tomography colonography

scientific article published on 13 September 2013

A validation of Illumina EPIC array system with bisulfite-based amplicon sequencing

scientific article published on 10 February 2021

ATF3 enhances c-Jun-mediated neurite sprouting

scientific article

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

scientific article published on 11 January 2020

Alternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants: an ENIGMA report

scientific article published on 19 March 2019

An investigation of the relationship between latitude and multiple sclerosis severity in New Zealand.

scientific article published on 2 October 2015

Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson's disease

scientific article published on 06 March 2020

Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's disease

scientific article

Assessing possible selection bias in a national voluntary MS longitudinal study in Australia

scientific article published on 25 March 2013

Assessment of intra-tumoural colorectal cancer prognostic biomarkers using RNA hybridisation

Association between fine particulate matter and diabetes prevalence in the U.S.

scientific article

Association of higher DEFB4 genomic copy number with Crohn's disease

scientific article published on 6 October 2009

Attitudes to aging in midlife are related to health conditions and mood

scientific article published on 20 August 2014

Characteristic changes in the EEG signals between microsleeps and preceding responsive states

scientific article published on 01 July 2019

Clinical and Genetic Risk Factors for Perianal Crohn's Disease in a Population-Based Cohort

scientific article published on 13 December 2011

Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia

scientific article

Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis

scientific article published on 30 September 2016

Computational Results in Topological Graph Theory

1997 doctoral thesis by John Pearson at University of Auckland

Conjugation of urate-derived electrophiles to proteins during normal metabolism and inflammation

scientific article published in Journal of Biological Chemistry

Contrasting signals of cardiovascular health among natriuretic peptides in subjects without heart disease

scientific article published on 20 August 2019

Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy

scientific article published on 15 May 2018

Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy

article

Correction: Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers

scientific article published on 01 January 2019

Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells

scientific article

Cytomegalovirus and Epstein-Barr virus in breast cancer

scientific article

Determining the limits and confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry

scientific article published on 17 August 2011

Dietary ascorbate intake affects steady state tissue concentrations in vitamin C-deficient mice: tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit)

scientific article published in December 2010

Dietary intake in midlife and associations with standard of living, education and nutrition literacy

scientific article published on 4 July 2014

Disability profile of multiple sclerosis in New Zealand

scientific article

Educational, employment, and social participation of young adult graduates from the paediatric Southern Cochlear Implant Programme, New Zealand

scientific article published on 27 July 2015

Effect of adjunctive single high-dose vitamin D on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial

scientific article published in Scientific Reports

Effect of genetic factors on the response to vitamin D3 supplementation in the VIDARIS randomized controlled trial

scientific article published on 12 February 2020

Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers

scientific article published on February 2017

Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease

scientific article published on 14 April 2015

Exploring the critical distance and position relationships between the Eustachian tube and the internal carotid artery.

scientific article published on December 2010

Expression and functional characterization of the serine protease inhibitor neuroserpin in endocrine cells

scientific journal article

Factors related to care home admission in the year following hospitalisation in frail older adults

scientific article published on 27 May 2011

Faecal biomarkers do not always identify pre-cancerous lesions in patients who present in primary care with bowel symptoms

scientific article published on 30 August 2019

Gastrointestinal Pathobionts in Pediatric Crohn's Disease Patients

scientific article published on 17 July 2018

Gene expression effects of lithium and valproic acid in a serotonergic cell line

article

Gene expression effects of lithium and valproic acid in a serotonergic cell line

scientific article published on 21 December 2018

Genetic and environmental contributions to size, color, shape, and other characteristics of melanocytic naevi in a sample of adolescent twins

article

Genetic association study of childhood aggression across raters, instruments, and age

scientific article

Genome Scale Epigenetic Profiling Reveals Five Distinct Subtypes of Colorectal Cancer

Genome-Wide Gene Expression Analyses of BRCA1- and BRCA2-Associated Breast and Ovarian Tumours

scientific article published on 16 October 2020

Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort

scientific article published on 22 April 2020

Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort

scientific article published on 4 November 2019

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics

scientific article

Home availability of fruit and vegetables and obesogenic foods as an indicator of nutrient intake in 50 year olds from Canterbury, New Zealand

scientific article

Home food availability is associated with multiple socio-economic indicators in 50 year olds from Canterbury, New Zealand

scientific article published on January 2014

Impact of increased access to novel agents on the survival of multiple myeloma patients treated at a single New Zealand centre

article

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

scientific article published on 23 August 2019

Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer

scientific article published on 4 February 2014

Increased gene expression variability in BRCA1-associated and basal-like breast tumours

scientific article published on 21 July 2021

Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry

scientific article published on 16 March 2017

Increased risk of major depression by childhood abuse is not modified by CNR1 genotype

scientific article published on 19 December 2012

Increasing Incidence of Young-Onset Colorectal Carcinoma: A Three-Country Population Analysis

scientific article published on 26 February 2020

Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas

scientific article published on 05 April 2019

Investigation of Experimental Factors That Underlie BRCA1/2 mRNA Isoform Expression Variation: Recommendations for Utilizing Targeted RNA Sequencing to Evaluate Potential Spliceogenic Variants.

scientific article

Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.

scientific article published on August 2017

Long-term incidence of dysplasia and colorectal cancer in an ulcerative colitis population-based cohort

scientific article published on 23 January 2020

Low Vitamin C Status in Patients with Cancer Is Associated with Patient and Tumor Characteristics

scientific article published on 5 August 2020

METHYLOME IMPACTS OF CANNABIS USE IN THE CHRISTCHURCH HEALTH AND DEVELOPMENT STUDY

scholarly article

MS prevalence in New Zealand, an ethnically and latitudinally diverse country

article

Mean telomere length is not associated with current health status in a 50-year-old population sample

article

Measures of temperament and character are differentially impacted on by depression severity

scientific article published on 8 April 2010

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

scientific article published on 26 March 2021

Method for identifying eligible individuals for a prevalence survey in the absence of a disease register or population register

scientific article

Methylomic changes in response to micronutrient supplementation and MTHFR genotype

scientific article published on 05 September 2018

MinION Sequencing of colorectal cancer tumour microbiomes-A comparison with amplicon-based and RNA-Sequencing

scientific article published on 20 May 2020

Molecular subtyping improves prognostication of Stage 2 colorectal cancer

scientific article published on 27 November 2019

Multiple Sclerosis impact on employment and income in New Zealand.

scientific article published on 28 November 2016

Multiple sclerosis in New Zealand Māori

scientific article published on 22 May 2014

Mutation load in melanoma is affected by MC1R genotype

scientific article published on 26 December 2016

Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation

scientific article published on 04 March 2020

NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease

scientific article

Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications

scientific article published on 01 September 2019

Neuroserpin is expressed in the pituitary and adrenal glands and induces the extension of neurite-like processes in AtT-20 cells

scientific article

Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells

scientific article (publication date: September 2002)

Next-Generation Sequencing of Endobronchial Ultrasound Transbronchial Needle Aspiration Specimens in Lung Cancer.

scientific article published in August 2017

No association between mean telomere length and life stress observed in a 30 year birth cohort

scientific article

No attributable effects of PRP on greater trochanteric pain syndrome

scientific article published on 13 December 2019

Ongoing adverse mental health impact of the earthquake sequence in Christchurch, New Zealand

scientific article published on 12 March 2014

Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency

scientific article

Parkinson's disease across ethnicities: A nationwide study in New Zealand

scientific article published on 23 July 2018

Pathway and network analysis of cancer genomes

scientific article (publication date: July 2015)

Personality, mental health and demographic correlates of hoarding behaviours in a midlife sample

scientific article published on 22 December 2016

Phosphohistone H3 outperforms Ki67 as a marker of outcome for breast cancer patients

scientific article

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant

scientific article

Potential for electronic health records and online social networking to redefine medical research

scientific article published on 15 December 2010

Potential sources of 2-aminoacetophenone to confound the Pseudomonas aeruginosa breath test, including analysis of a food challenge study.

scientific article published on 23 June 2011

Prevalence of concurrent deep vein thrombosis in patients with lower limb cellulitis: a prospective cohort study

scientific article

Profiling copy number alterations in cell-free tumour DNA using a single-reference

Quantifying BRCA1 and BRCA2 mRNA Isoform Expression Levels in Single Cells ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Quantifying and mRNA Isoform Expression Levels in Single Cells

scholarly article

Quantifying mitochondrial respiration in human lymphocytes and monocytes challenged with hydrogen peroxide

scientific article published on 24 April 2020

RNAscope compatibility with image analysis platforms for the quantification of tissue-based colorectal cancer biomarkers in archival formalin-fixed paraffin-embedded tissue

Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition

scientific article published on 9 November 2014

Relationship between fructose and lactose intakes and functional gastrointestinal symptoms in a sample of 50-year-old Cantabrians in New Zealand.

scientific article published on 28 November 2014

Risk communication methods in hip fracture prevention: a randomised trial in primary care

scientific article

SLC11A1 polymorphisms in inflammatory bowel disease and Mycobacterium avium subspecies paratuberculosis status

scientific article published on December 2010

Screening for enterotoxigenic Bacteroides fragilis in stool samples

scientific article published on 7 May 2016

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Statin use and risk of acute diverticulitis: A population-based case-control study

scientific article published on 01 May 2020

Survival of myeloma patients following the introduction of thalidomide as a second-line therapy: a retrospective study at a single New Zealand centre.

scientific article published in February 2013

Telomere length measurement on the Roche LightCycler 480 Platform

scientific article published on 23 December 2014

Temperament and character as determinants of well-being

scientific article published on 27 June 2014

The Anorexia Nervosa Genetics Initiative: Overview and Methods

article

The Role of Constitutional Copy Number Variants in Breast Cancer

scientific article published on 08 September 2015

The anorexia nervosa genetics initiative (ANGI): Overview and methods

article

The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues

scientific article

The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain

scientific article published in January 2005

The genetic architecture of the human cerebral cortex

The genetic architecture of the human cerebral cortex

scientific article

The increasing prevalence of multiple sclerosis in New Zealand

scientific article published on 20 February 2014

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scholarly article published 10 March 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

Tumor mutation burden and structural chromosomal aberrations are not associated with T-cell density or patient survival in acral, mucosal, and cutaneous melanomas

scientific article published on 11 September 2020

Under-ascertainment of breast cancer susceptibility gene carriers in a cohort of New Zealand female breast cancer patients

scientific article published on 28 October 2020

Upstream genetic variant near INSIG2, influences response to carnitine supplementation in bipolar patients with valproate-induced weight gain

scientific article published in June 2009

Variable expression quantitative trait loci analysis of breast cancer risk variants

scientific article published in 2021

Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study

scientific article published on 3 August 2017

Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours

scientific article published on 15 May 2020

Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility

scientific article published on 21 November 2018

Whole-genome landscapes of major melanoma subtypes.

scientific article published on 3 May 2017

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