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List of works by Louis Vermeulen

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities

scientific article published on 10 June 2020

A marker-independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue

scientific article published on 16 August 2019

A mouse model for peritoneal metastases of colorectal origin recapitulates patient heterogeneity

scientific article published on 05 June 2020

A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.

scientific article published on 09 May 2016

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

scientific article

Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study

scientific article published on 24 June 2020

Bcl-2 is a critical mediator of intestinal transformation

scientific article published on 9 March 2016

Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity

scientific article

CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status

scientific article

CFTR is a tumor suppressor gene in murine and human intestinal cancer

scientific article published on 11 January 2016

Cancer heterogeneity--a multifaceted view

scientific article

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

scientific article published in January 2010

Cancer stem cells--old concepts, new insights.

scientific article published on 15 February 2008

Chromosomal copy number heterogeneity predicts survival rates across cancers

scientific article published on 27 May 2021

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

scientific article published on 21 March 2016

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

scientific article

Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes

scientific article

Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

scientific article published on 5 January 2018

Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.

scientific article

Correction: Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

scientific article published on 01 November 2019

Defining stem cell dynamics in models of intestinal tumor initiation

scientific article published in November 2013

Dissecting cancer heterogeneity--an unsupervised classification approach

scientific article published on September 2013

ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy

scientific article

Exploiting KRAS-mediated metabolic reprogramming as a therapeutic target

scientific article published on 01 January 2021

Exploring cancer stem cell niche directed tumor growth.

scientific article published on 15 April 2010

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.

scientific article published on 15 February 2012

Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

scientific article published on 26 November 2018

Interconnectivity between molecular subtypes and tumor stage in colorectal cancer

scientific article published on 04 September 2020

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

scientific article

Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development

scientific article published on 03 December 2020

Keeping Stem Cells in Check: A Hippo Balancing Act ⬇️

scientific article published on January 3, 2013

Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients

scientific article published in November 2011

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer ⬇️

scientific article published on June 15, 2011

Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors

scientific article (publication date: May 2011)

Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer

scientific article

One renegade cancer stem cell?

scientific article

Polycomb complex PRC1 as gatekeeper of intestinal stem cell identity

scientific article published on 15 June 2016

Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry

scientific article published on 26 July 2016

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications.

scientific article published on 09 January 2014

Serrated neoplasia-role in colorectal carcinogenesis and clinical implications

scientific article published on 12 May 2015

Stem cell competition: how speeding mutants beat the rest

scientific article published on September 2014

Stem cell dynamics in homeostasis and cancer of the intestine

scientific article

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.

scientific article published on 3 September 2018

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

scientific article

Targeting Wnt signaling in colon cancer stem cells

scientific article published on 15 December 2010

The Use of Targeted Therapies for Precision Medicine in Oncology

scientific article published on 27 September 2016

The consensus molecular subtypes of colorectal cancer

scientific article

The developing cancer stem-cell model: clinical challenges and opportunities

scientific article published on February 2012

The effect of environmental chemicals on the tumor microenvironment

scientific article

Turning off the BCL-2 switch to prevent intestinal tumorigenesis

scientific article published on 15 April 2016

Wnt Signaling in Cancer Stem Cell Biology

scientific article

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

scientific article (publication date: May 2010)

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