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List of works by Shinya Fushinobu

"Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.

scientific article

1,3-1,4- -L-Fucosynthase That Specifically Introduces Lewis a/x Antigens into Type-1/2 Chains

scientific article

A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem

scientific article published in 2023

A eukaryotic copper-containing nitrite reductase derived from a NirK homolog gene of Aspergillus oryzae

scientific article published on 7 May 2010

A molecular design that stabilizes active state in bacterial allosteric L-lactate dehydrogenases

article

A novel enzymatic system against oxidative stress in the thermophilic hydrogen-oxidizing bacterium Hydrogenobacter thermophilus

scientific article

A series of crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with various cleavage products

scientific article published in March 2005

Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase

scientific article

Advenella faeciporci sp. nov., a nitrite-denitrifying bacterium isolated from nitrifying-denitrifying activated sludge collected from a laboratory-scale bioreactor treating piggery wastewater.

scientific article

Allosteric activation of L-lactate dehydrogenase analyzed by hybrid enzymes with effector-sensitive and -insensitive subunits.

scientific article

Alternative strategy for converting an inverting glycoside hydrolase into a glycosynthase

scientific article published on 9 February 2008

An absolute requirement of fructose 1,6-bisphosphate for the Lactobacillus casei L-lactate dehydrogenase activity induced by a single amino acid substitution.

scientific article published in January 2002

An inverting β-1,2-mannosidase belonging to glycoside hydrolase family 130 fromDyadobacter fermentans

scholarly article by Takanori Nihira published in October 2015

Archaeal ADP-dependent phosphofructokinase: expression, purification, crystallization and preliminary crystallographic analysis

scientific article published on 27 June 2003

Archaeal Mo-Containing Glyceraldehyde Oxidoreductase Isozymes Exhibit Diverse Substrate Specificities through Unique Subunit Assemblies

scientific article published on 25 January 2016

Archaeal aldehyde dehydrogenase ST0064 from Sulfolobus tokodaii, a paralog of non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, is a succinate semialdehyde dehydrogenase

scientific article published on 7 June 2013

Aspergillus oryzae flavohemoglobins promote oxidative damage by hydrogen peroxide

scientific article published on 06 March 2010

Author Correction: Identification and characterization of a novel β-D-galactosidase that releases pyruvylated galactose

scientific article published on 13 February 2020

Bioaugmentation of a wastewater bioreactor system with the nitrous oxide-reducing denitrifier Pseudomonas stutzeri strain TR2.

scientific article published on 19 September 2012

Biochemical and structural analyses of a bacterial endo-β-1,2-glucanase reveal a new glycoside hydrolase family

scientific article published on 7 March 2017

Biochemical characterization of a glycoside hydrolase family 61 endoglucanase from Aspergillus kawachii.

scientific article published on 11 December 2007

Biochemical characterization of recombinant acetyl xylan esterase from Aspergillus awamori expressed in Pichia pastoris: mutational analysis of catalytic residues

scientific article published in May 2005

Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

scientific article published on 03 July 2020

Characterization and crystal structure determination of β-1,2-mannobiose phosphorylase from Listeria innocua

scientific article

Characterization of a chimeric enzyme comprising feruloyl esterase and family 42 carbohydrate-binding module

scientific article published on 16 September 2009

Characterization of a thermostable carboxylesterase from the hyperthermophilic bacterium Thermotoga maritima.

scientific article

Characterization of the cupin-type phosphoglucose isomerase from the hyperthermophilic archaeon Thermococcus litoralis.

scientific article

Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold

scientific article

Cloning and characterization of two flavohemoglobins from Aspergillus oryzae

scientific article

Comparative analysis of two glyceraldehyde-3-phosphate dehydrogenases from a thermoacidophilic archaeon, Sulfolobus tokodaii

article

Computational analyses of the conformational itinerary along the reaction pathway of GH94 cellobiose phosphorylase

scientific article

Conformations of the type-1 lacto-N-biose I unit in protein complex structures

article published in 2018

Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase, Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes

scientific article published on 3 June 2015

Crystal Structure and Substrate Specificity Modification of Acetyl Xylan Esterase from Aspergillus luchuensis

scientific article published on 11 August 2017

Crystal Structure of Glycoside Hydrolase Family 55  -1,3-Glucanase from the Basidiomycete Phanerochaete chrysosporium

scientific article

Crystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation State

scientific article

Crystal Structures of Glycoside Hydrolase Family 51 α-L-Arabinofuranosidase fromThermotoga maritima

scientific article published on February 7, 2012

Crystal Structures of Phosphoketolase: THIAMINE DIPHOSPHATE-DEPENDENT DEHYDRATION MECHANISM

scientific article

Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic β-glucosidase Td2F2

scientific article

Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H).

scientific article published in August 2005

Crystal structure of a family 54 alpha-L-arabinofuranosidase reveals a novel carbohydrate-binding module that can bind arabinose

scientific article

Crystal structure of a feruloyl esterase belonging to the tannase family: A disulfide bond near a catalytic triad

article

Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase

scientific article

Crystal structure of cobalt-containing nitrile hydratase

scientific article

Crystal structure of glycoside hydrolase family 127 β-l-arabinofuranosidase from Bifidobacterium longum

scientific article

Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium

scientific article

Crystal structure of isocitrate dehydrogenase from Aeropyrum pernix

scientific article

Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces

scientific article

Crystal structure of sulerythrin, a rubrerythrin-like protein from a strictly aerobic archaeon, Sulfolobus tokodaii strain 7, shows unexpected domain swapping

scientific article

Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus: involvement of hydrophobic dimer-dimer interaction in extremely high thermotolerance

scientific article published on October 2005

Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution

scientific article

Crystal structure of the central and the C-terminal RNase domains of colicin D implicated its translocation pathway through inner membrane of target cell

scientific article published on 01 November 2018

Crystal structure of the ferredoxin component of carbazole 1,9a-dioxygenase of Pseudomonas resinovorans strain CA10, a novel Rieske non-heme iron oxygenase system

scientific article published in March 2005

Crystal structure of the liganded anti-gibberellin A(4) antibody 4-B8(8)/E9 Fab fragment

scientific article

Crystal structure of the terminal oxygenase component of cumene dioxygenase from Pseudomonas fluorescens IP01.

scientific article

Crystal structure of β-L-arabinobiosidase belonging to glycoside hydrolase family 121

scientific article published on 01 June 2020

Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor

scientific article (publication date: 23 May 2003)

Crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with cleavage products

scientific article

Crystal structures of archaeal 2-oxoacid:ferredoxin oxidoreductases from Sulfolobus tokodaii

scientific article published on 13 September 2016

Crystal structures of glycoside hydrolase family 3 β-glucosidase 1 from Aspergillus aculeatus

scientific article

Crystallization and preliminary X-ray analysis of cellobiose phosphorylase from Cellvibrio gilvus

scientific article published on 23 September 2004

Crystallization and preliminary X-ray analysis of cytosolic alpha-mannosidase from Thermotoga maritima

scientific article

Crystallization and preliminary X-ray analysis of reducing-end xylose-releasing exo-oligoxylanase from Bacillus halodurans C-125.

scientific article

Crystallization and preliminary X-ray analysis of xylanase B from Clostridium stercorarium

scientific article published on 23 January 2004

Crystallographic and mutational analyses of an extremely acidophilic and acid-stable xylanase: biased distribution of acidic residues and importance of Asp37 for catalysis at low pH

scientific article

Discovery of α-L-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42.

scientific article published on 23 October 2017

Distinct conformation-mediated functions of an active site loop in the catalytic reactions of NAD-dependent D-lactate dehydrogenase and formate dehydrogenase.

scientific article

Effectiveness of heat treatment to protect introduced denitrifying bacteria from eukaryotic predatory microorganisms in a pilot-scale bioreactor

scientific article published on 28 June 2013

Engineering the allosteric properties of archaeal non-phosphorylating glyceraldehyde-3-phosphate dehydrogenases

scientific article

Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer

scientific article published in September 2004

Expression, purification, crystallization and preliminary X-ray analysis of α-L-arabinofuranosidase B fromAspergillus kawachii

article

Four Cys residues in heterodimeric 2-oxoacid:ferredoxin oxidoreductase are required for CoA-dependent oxidative decarboxylation but not for a non-oxidative decarboxylation

scientific article published on 31 January 2014

Functional analysis and subcellular location of two flavohemoglobins from Aspergillus oryzae

scientific article published on 9 September 2010

Fungal denitrification and nitric oxide reductase cytochrome P450nor

scientific article published on May 2012

Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis

scientific article

Homotropic Activation via the Subunit Interaction and Allosteric Symmetry Revealed on Analysis of Hybrid Enzymes ofl-Lactate Dehydrogenase

scientific article published in Journal of Biological Chemistry

Hydroxylation of Compactin (ML-236B) by CYP105D7 (SAV_7469) from Streptomyces avermitilis

scientific article published on 9 March 2017

Identification and characterization of a novel β-D-galactosidase that releases pyruvylated galactose

scientific article published in Scientific Reports

Identification and characterization of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii

scientific article published on March 2006

Identification of the Flavonoid Luteolin as a Repressor of the Transcription Factor Hepatocyte Nuclear Factor 4α

scientific article

Identification of the catalytic residue of Thermococcus litoralis 4-alpha-glucanotransferase through mechanism-based labeling.

scientific article published in October 2001

Identification of the catalytic residues of sequence-specific and histidine-free ribonuclease colicin E5

scientific article published on July 18, 2012

Identification of the lysine residue responsible for coenzyme A binding in the heterodimeric 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus tokodaii, a thermoacidophilic archaeon, using 4-fluoro-7-nitrobenzofurazan as an affinity label

scientific article published on 5 November 2008

Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01.

scientific article published on 7 June 2006

Involvement of a Glu71-Arg64 couple in the access channel for NADH in cytochrome p450nor

scientific article

Isolation and characterization of a thermostable lipase from Bacillus thermoamylovorans NB501.

scientific article published on 22 November 2016

Ligand complex structures of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 and its conformational change.

scientific article published on 8 February 2018

Mechanistic insight into the substrate specificity of 1,2-β-oligoglucan phosphorylase from Lachnoclostridium phytofermentans

scientific article

Metalloproteins: A new face for biomass breakdown

scientific article published on 22 December 2013

Molecular Anatomy of the Alkaliphilic Xylanase from Bacillus halodurans C-125

scientific article published in 2007

Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum.

scientific article published on 4 April 2017

Molecular analysis of cyclic α-maltosyl-(1→6)-maltose binding protein in the bacterial metabolic pathway

scientific article published on 19 November 2020

Multiple rewards from a treasure trove of novel glycoside hydrolase and polysaccharide lyase structures: new folds, mechanistic details, and evolutionary relationships

scientific article published on 28 June 2013

Mutational analysis of N-glycosylation recognition sites on the biochemical properties of Aspergillus kawachii alpha-L-arabinofuranosidase 54.

scientific article published on 13 May 2006

Mutational analysis of a feruloyl esterase from Aspergillus awamori involved in substrate discrimination and pH dependence

scientific article

Mutational and crystallographic analysis ofl-amino acid oxidase/monooxygenase fromPseudomonassp. AIU 813: Interconversion between oxidase and monooxygenase activities

scientific article

N-Linked Oligosaccharides of Aspergillus awamori Feruloyl Esterase Are Important for Thermostability and Catalysis

scientific article published on 07 October 2006

Nitrous oxide emission from nitrifying activated sludge dependent on denitrification by ammonia-oxidizing bacteria

scientific article published on 6 February 2010

Occurrence, properties, and applications of feruloyl esterases.

scientific article published on 31 July 2009

Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase

scientific article

Overexpression, crystallization and preliminary X-ray analysis of xylulose-5-phosphate/fructose-6-phosphate phosphoketolase from Bifidobacterium breve

scientific article

Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis

scientific article

Phase-diagram-guided method for growth of a large crystal of glycoside hydrolase family 45 inverting cellulase suitable for neutron structural analysis.

scientific article published on 25 September 2013

Potential of aerobic denitrification by Pseudomonas stutzeri TR2 to reduce nitrous oxide emissions from wastewater treatment plants

scientific article published on 21 May 2010

Preparation of p-nitrophenyl β-l-arabinofuranoside as a substrate of β-l-arabinofuranosidase

scientific article published on 14 October 2013

Purification, characterization, and steady-state kinetics of a meta-cleavage compound hydrolase from Pseudomonas fluorescens IPO1.

scientific article published in January 2002

Purification, crystallization and preliminary X-ray analysis of beta-glucosidase from Kluyveromyces marxianus NBRC1777

scientific article (publication date: November 2009)

Purification, crystallization and preliminary X-ray analysis of the galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum JCM1217.

scientific article published on 10 August 2007

Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis

scientific article published on 22 November 2019

Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.

scientific article

Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 β-glucosidase from Kluyveromyces marxianus

scientific article

Role of subsite +1 residues in pH dependence and catalytic activity of the glycoside hydrolase family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium

scientific article published in April 2008

Second transmembrane segment of FtsH plays a role in its proteolytic activity and homo-oligomerization

scientific article published on 01 November 1999

Some Lactobacillus L-lactate dehydrogenases exhibit comparable catalytic activities for pyruvate and oxaloacetate

scientific article

Streptococcus pneumoniae hijacks host autophagy by deploying CbpC as a decoy for Atg14 depletion

scientific article published on 02 April 2020

Streptomyces griseus enhances denitrification by Ralstonia pickettii K50, which is possibly mediated by histidine produced during co-culture

scientific article published on 7 January 2008

Structural Basis for Reversible Phosphorolysis and Hydrolysis Reactions of 2-O- -Glucosylglycerol Phosphorylase

scientific article

Structural Insight into concerted inhibition of alpha 2 beta 2-type aspartate kinase from Corynebacterium glutamicum

scientific article

Structural analysis of β-L-arabinobiose-binding protein in the metabolic pathway of hydroxyproline-rich glycoproteins in Bifidobacterium longum

scientific article published on 04 April 2020

Structural and Biochemical Analyses of Glycoside Hydrolase Family 26  -Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus

scientific article

Structural and mutational analysis of substrate recognition in kojibiose phosphorylase

scientific article

Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I

scientific article

Structural and thermodynamic insights into β-1,2-glucooligosaccharide capture by a solute-binding protein in Listeria innocua.

scientific article

Structural basis for broad substrate specificity of UDP-glucose 4-epimerase in the human milk oligosaccharide catabolic pathway of Bifidobacterium longum

scientific article published on 31 July 2019

Structural basis for selectivity in a highly reducing type II polyketide synthase

scientific article published on 04 May 2020

Structural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenase

scientific article

Structural basis for the ADP-specificity of a novel glucokinase from a hyperthermophilic archaeon

scientific article

Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant

scientific article published on 30 June 2006

Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase

scientific article

Structural basis for the specific cleavage of core-fucosylated N-glycans by endo-β-N-acetylglucosaminidase from the fungus Cordyceps militaris

scientific article published on 23 September 2019

Structural basis for the specificity of the reducing end xylose-releasing exo-oligoxylanase from Bacillus halodurans C-125.

scientific article

Structural dissection of the reaction mechanism of cellobiose phosphorylase

scientific article published on August 2006

Structural explanation for the acquisition of glycosynthase activity

scientific article

Structural features of a bacterial cyclic α-maltosyl-(1→6)-maltose (CMM) hydrolase critical for CMM recognition and hydrolysis

scientific article published in Journal of Biological Chemistry

Sulfolobus tokodaii ST2133 is characterized as a thioredoxin reductase-like ferredoxin:NADP+ oxidoreductase

scientific article published in December 2013

Survival of the aerobic denitrifier Pseudomonas stutzeri strain TR2 during co-culture with activated sludge under denitrifying conditions.

scientific article published in January 2012

The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase

scientific article published on 25 September 2014

The crystal structure of an inverting glycoside hydrolase family 9 exo-β-D-glucosaminidase and the design of glycosynthase

scientific article

The crystal structure of galacto-N-biose/lacto-N-biose I phosphorylase: a large deformation of a TIM barrel scaffold

scientific article

The family 42 carbohydrate-binding module of family 54 alpha-L-arabinofuranosidase specifically binds the arabinofuranose side chain of hemicellulose

scientific article

The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors

scientific article published on 25 May 2017

The first crystal structure of the novel class of fructose-1,6-bisphosphatase present in thermophilic archaea.

scientific article

The possible involvement of copper-containing nitrite reductase (NirK) and flavohemoglobin in denitrification by the fungus Cylindrocarpon tonkinense

scientific article published on 7 July 2010

The role of conserved arginine residue in loop 4 of glycoside hydrolase family 10 xylanases

scientific article published in May 2005

Trimeric crystal structure of the glycoside hydrolase family 42 beta-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactose

scientific article

Understanding the Molecular Mechanism Underlying the High Catalytic Activity of p-Hydroxybenzoate Hydroxylase Mutants for Producing Gallic Acid

scientific article published on 01 November 2019

Unique sugar metabolic pathways of bifidobacteria

scientific article published on 07 December 2010

[Physiological function, reaction mechanism, and structure of cytochrone P450nor]

scientific article published on 01 June 2008

α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway

scientific article published on 16 November 2011