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List of works by Peter L Roach

A device for the high-pressure oxygenation of protein crystals

article

A real-time assay for CpG-specific cytosine-C5 methyltransferase activity

scientific article published on 5 February 2010

Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction

scientific article

An analysis of the feasibility of short read sequencing

scientific article

Bead-based immunoassays using a micro-chip flow cytometer

scientific article published on 14 June 2007

Biochemical and structural characterization of polyphosphate kinase 2 from the intracellular pathogen Francisella tularensis

scientific article

Biochemical studies on Francisella tularensis RelA in (p)ppGpp biosynthesis

scientific article published on 8 October 2015

Catalytic activity of the anaerobic tyrosine lyase required for thiamine biosynthesis in Escherichia coli

scientific article published on 18 November 2009

Diffractive micro bar codes for encoding of biomolecules in multiplexed assays

scientific article

Effect of iron-sulfur cluster assembly proteins on the expression of Escherichia coli lipoic acid synthase

scientific article published in April 2003

High-level expression and reconstitution of active Cfr, a radical-SAM rRNA methyltransferase that confers resistance to ribosome-acting antibiotics

scientific article

Kinetic analysis of Yersinia pestis DNA adenine methyltransferase activity using a hemimethylated molecular break light oligonucleotide

scientific article

Kinetics and thermodynamics of biotinylated oligonucleotide probe binding to particle-immobilized avidin and implications for multiplexing applications

scientific article

Lipoyl synthase inserts sulfur atoms into an octanoyl substrate in a stepwise manner

scientific article published on 01 August 2006

Metallocofactor assembly for [FeFe]-hydrogenases

scientific article published on 23 June 2016

Multiplexed suspension array platform for high-throughput protein assays.

scientific article

Multistep Synthesis on SU-8: Combining Microfabrication and Solid-Phase Chemistry on a Single Material

scientific article published on 07 April 2007

Observation of the iron-sulfur cluster in Escherichia coli biotin synthase by nanoflow electrospray mass spectrometry

scientific article published in September 2001

Optimized conjugation of a fluorescent label to proteins via intein-mediated activation and ligation

scientific article published in March 2004

Product inhibition in the radical S-adenosylmethionine family

scientific article

Radical S-adenosylmethionine enzymes: mechanism, control and function

scientific article published on 21 July 2011

Radicals from S-adenosylmethionine and their application to biosynthesis

scientific article published on 13 December 2010

Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli

scientific article published on 7 February 2002

Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions

scientific article

Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures.

scientific article published on 12 March 2018

The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate

scientific article published on 03 February 2006

The rhodanese domain of ThiI is both necessary and sufficient for synthesis of the thiazole moiety of thiamine in Salmonella enterica

scientific article

Thiamine biosynthesis in Escherichia coli: identification of the intermediate and by-product derived from tyrosine.

scientific article

Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity

scientific article published on 2 February 2004

Thiamine biosynthesis in Escherichia coli: isolation and initial characterisation of the ThiGH complex.

scientific article

Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro.

scientific article

Thin Film Polycrystalline Silicon Nanowire Biosensors

scientific article published on 26 March 2012

X-ray crystallographic and EPR spectroscopic analysis of HydG, a maturase in [FeFe]-hydrogenase H-cluster assembly

scientific article

[FeFe]-hydrogenase cyanide ligands derived from S-adenosylmethionine-dependent cleavage of tyrosine.

scientific article published in February 2010

[FeFe]-hydrogenase maturation: HydG-catalyzed synthesis of carbon monoxide.

scientific article published in July 2010