List of works by Filippo de Braud

"Systemic strategy at the patient's service": a congress report on supportive care in oncology.

scientific article published on 27 July 2017

"Waiting and the waiting room: how do you experience them?" emotional implications and suggestions from patients with cancer.

scientific article

5'-nucleotidase cN-II emerges as a new predictive biomarker of response to gemcitabine/platinum combination chemotherapy in non-small cell lung cancer.

scientific article published on 16 February 2018

5-Fluorouracil as protracted continuous intravenous infusion can be added to full-dose docetaxel (Taxotere)-cisplatin in advanced gastric carcinoma: a phase I-II trial

scientific article published in May 2004

A 15-min premedication for 1-h paclitaxel infusion: optimizing patients' care

scientific article published on 18 September 2007

A Phase I Study of the Anti-Activin Receptor-Like Kinase 1 (ALK-1) Monoclonal Antibody PF-03446962 in Patients with Advanced Solid Tumors

scientific article

A catalyst for change: the European cancer Patient's Bill of Rights

scientific article published on 03 February 2014

A classification prognostic score to predict OS in stage IV well-differentiated neuroendocrine tumors.

scientific article

A dose-escalation and signal-generating study of the immunocytokine L19-IL2 in combination with dacarbazine for the therapy of patients with metastatic melanoma.

scientific article published on 25 October 2011

A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma

scientific article published on 08 October 2012

A new nomogram for estimating survival in patients with brain metastases secondary to colorectal cancer

scientific article published on 4 September 2015

A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of a dual VEGFR and FGFR inhibitor, brivanib, in patients with advanced or metastatic solid tumors

scientific article

A phase I, dose-escalation study of volasertib combined with nintedanib in advanced solid tumors.

scientific article published on 22 September 2015

A proper schedule of weekly paclitaxel and gemcitabine combination is highly active and very well tolerated in NSCLC patients

scientific article

ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.

scientific article published in December 2017

Absence of epidermal growth factor receptor gene mutations in patients with hormone refractory prostate cancer not responding to gefitinib

article

Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma.

scientific article

Activity and safety of RAD001 (everolimus) in patients affected by biliary tract cancer progressing after prior chemotherapy: a phase II ITMO study

scientific article

Activity of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring rare epidermal growth factor receptor mutations

scientific article

Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.

scientific article

Adjuvant chemotherapy in new stage II pN0 non-small cell lung cancer: a new issue for a case-by-case decision making process

scientific article published on 01 May 2010

An open-label, single-arm, phase 2 study of the Aurora kinase A inhibitor alisertib in patients with advanced urothelial cancer.

scientific article

Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy

scientific article

Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production

scientific article

Antibody-guided three-step therapy for high grade glioma with yttrium-90 biotin

scientific article published in April 1999

Antitumor activity and safety profile of weekly carboplatin plus paclitaxel in metastatic breast cancer: a ten-year, monocentric, retrospective study.

scientific article published on 14 June 2017

Approaches to interim analysis of cancer randomised clinical trials with time to event endpoints: a survey from the Italian National Monitoring Centre for Clinical Trials.

scientific article published on 25 July 2008

Aprepitant versus dexamethasone for delayed emesis: what is the role of the 5-hydroxytryptamine type 3 receptor antagonist palonosetron?

scientific article published on 09 June 2014

Available evidence and new biological perspectives on medical treatment of advanced thymic epithelial tumors

scientific article published on 19 November 2014

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

scientific article published on 7 July 2015

BRAF in metastatic colorectal cancer: the future starts now.

scientific article

Bax expression is predictive of favorable clinical outcome in chemonaive advanced gastric cancer patients treated with capecitabine, oxaliplatin, and irinotecan regimen

scientific article

Best choice of central venous insertion site for the prevention of catheter-related complications in adult patients who need cancer therapy: a randomized trial

scientific article published on 29 January 2009

Better Together: Targeted Combination Therapies in Breast Cancer

scientific article

Bevacizumab treatment in the elderly patient with metastatic colorectal cancer

scientific article

Bevacizumab-based neoadjuvant chemotherapy for colorectal cancer liver metastases: Pitfalls and helpful tricks in a review for clinicians.

scientific article published on 25 April 2015

Bilateral parotid gland metastases from gastric signet-ring cell carcinoma

scientific article published on 08 May 2018

Biological insights into BRAF(V600) mutations in melanoma patient: Not mere therapeutic targets

scientific article published on 3 July 2013

Biological targeted therapies in patients with advanced enteropancreatic neuroendocrine carcinomas

scientific article

Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study.

scientific article published on 5 December 2017

Bladder cancer

scientific article published on 01 January 2002

Body mass index and clinical benefit of fulvestrant in postmenopausal women with advanced breast cancer

scientific article published on 10 May 2016

Breast carcinoma in elderly women: features of disease presentation, choice of local and systemic treatments compared with younger postmenopasual patients.

scientific article

Butterfly and renal cell cancer: out of chaos comes order.

scientific article published on 28 July 2014

CDX-2 should be included in the work-up of patients with lung metastases from unknown primary

scientific article published on 01 December 2004

Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapy

scientific article

Cancer of the prostate.

scientific article

Capecitabine initially concomitant to radiotherapy then perioperatively administered in locally advanced rectal cancer.

scientific article published on 11 February 2009

Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer.

scientific article

Challenging Lung Carcinoma with Coexistent ΔNp63/p40 and Thyroid Transcription Factor-1 Labeling Within the Same Individual Tumor Cells.

scientific article published in October 2015

Characterization of the response of human thymocytes and blood lymphocytes to the synergistic mitogenicity of 12-O-tetradecanoylphorbol-13-acetate (TPA)-ionomycin

scientific article published on 01 August 1984

Chemotherapy or targeted therapy as second-line treatment of advanced gastric cancer. A systematic review and meta-analysis of published studies

scientific article

Chromogranin A as a marker of neuroendocrine neoplasia: an Italian Multicenter Study

article

Circulating biomarkers in advanced colorectal cancer patients randomly assigned to three bevacizumab-based regimens

scientific article

Circulating tumor cells as a longitudinal biomarker in patients with advanced chemorefractory, RAS-BRAF wild-type colorectal cancer receiving cetuximab or panitumumab.

scientific article

Clinical Behavior and Treatment Response of Epstein-Barr Virus-Positive Metastatic Gastric Cancer: Implications for the Development of Future Trials

scientific article published on 09 April 2020

Clinical Impact of Pancreatic Metastases from Renal Cell Carcinoma: A Multicenter Retrospective Analysis

scientific article

Clinical Response of Carcinomas Harboring the BRD4-NUT Oncoprotein to the Targeted Bromodomain Inhibitor OTX015/MK-8628

scientific article

Clinical experience with temsirolimus in the treatment of advanced renal cell carcinoma

scientific article published on June 2015

Clinical implications for pro-GRP in small cell lung cancer. A single center experience.

scientific article published on 25 September 2017

Clinical outcome of HER2-positive breast cancer patients after failure on adjuvant trastuzumab: the potential of the time to relapse.

scientific article

Cognitive impairment and chemotherapy: a brief overview

scientific article published on 14 August 2017

Colon cancer

scientific article published on 01 May 2010

Colon cancer

scientific article published on 01 August 2004

Colorectal cancer

scientific article published on 01 February 1998

Combination or single-agent chemotherapy as adjuvant treatment of gastric cancer: A systematic review and meta-analysis of published trials

scientific article published on 9 October 2015

Combination therapies for patients with metastatic renal cell carcinoma.

scientific article published on 9 February 2018

Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma

scientific article

Combined therapy with dabrafenib and trametinib in BRAF-mutated metastatic melanoma in a real-life setting: the INT Milan experience.

scientific article

Combined treatment of advanced oropharyngeal cancer with external radiotherapy and three-step radioimmunotherapy

scientific article published on 01 September 1998

Complete remission in metastatic breast cancer: expecting the unexpected-results of a cross-sectional study

scientific article published on 05 January 2017

Concomitant EML4-ALK rearrangement and EGFR mutation in non small cell lung cancer patients: A literature review of 100 cases.

scientific article

DPD and UGT1A1 deficiency in colorectal cancer patients receiving triplet chemotherapy with fluoropyrimidines, oxaliplatin and irinotecan

scientific article

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

scientific article published on 06 February 2019

Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

scientific article

Deciphering intra-tumor heterogeneity of lung adenocarcinoma confirms that dominant, branching, and private gene mutations occur within individual tumor nodules

scientific article published on 7 April 2016

Dendritic cell sarcoma: an analytic overview of the literature and presentation of original five cases.

scientific article published on 19 July 2007

Diagnosis and management of typical and atypical lung carcinoids

scientific article published on 18 February 2016

Diet and supplements in cancer prevention and treatment: Clinical evidences and future perspectives.

scientific article published on 2 February 2018

Differential histopathologic parameters in colorectal cancer liver metastases resected after triplets plus bevacizumab or cetuximab: a pooled analysis of five prospective trials.

scientific article published on 13 March 2018

Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients.

scientific article published on 16 December 2016

Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.

scientific article published on 25 June 2015

Disease progression pattern in metastatic breast cancer patients treated with anti-HER2 therapies

scientific article published on 21 January 2015

Dissecting Pulmonary Large-Cell Carcinoma by Targeted Next Generation Sequencing of Several Cancer Genes Pushes Genotypic-Phenotypic Correlations to Emerge

scientific article published on 26 August 2015

Do we really need another epidermal growth factor receptor tyrosine kinase inhibitor in first-line treatment for patients with non-small-cell lung cancer and EGFR mutations?

scientific article published on 03 February 2014

Does Dose Modification Affect Efficacy of First-Line Pazopanib in Metastatic Renal Cell Carcinoma?

scientific article published on 11 August 2017

Does immunohistochemistry affect response to therapy and survival of inoperable non-small cell lung carcinoma patients? A survey of 145 stage III-IV consecutive cases.

scientific article

Doing more with less: fluorescence in situ hybridization and gene sequencing assays can be reliably performed on archival stained tumor tissue sections

scientific article published on 27 January 2016

Dose-Dense Temozolomide in Patients with MGMT-Silenced Chemorefractory Colorectal Cancer

scientific article published on 4 November 2015

Drug-induced QTc interval prolongation: a proposal towards an efficient and safe anticancer drug development.

scientific article

Early tumour shrinkage as a prognostic factor and surrogate end-point in colorectal cancer: a systematic review and pooled-analysis

scientific article published on 17 March 2015

Effect of age and single versus multiple dose pharmacokinetics of letrozole (Femara) in breast cancer patients

scientific article published in July 2001

Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study

scientific article published on 12 January 2011

Efficacy and Safety of Onartuzumab in Combination With First-Line Bevacizumab- or Pemetrexed-Based Chemotherapy Regimens in Advanced Non-Squamous Non-Small-Cell Lung Cancer

scientific article published on 19 October 2016

Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer

scientific article

Emerging toxicities in the treatment of non-small cell lung cancer: ocular disorders.

scientific article published on 10 July 2013

Entering the third decade of experience with octreotide LAR in neuroendocrine tumors: A review of current knowledge.

scientific article

Epidermal growth factor receptor serum (sEGFR) level may predict response in patients with EGFR-positive advanced colorectal cancer treated with gefitinib?

scientific article

Erlotinib combined with cyclosporine in a liver-transplant recipient with epidermal growth factor receptor-mutated non-small cell lung cancer

scientific article

Evaluation of Local Oncologic Safety in Nipple-Areola Complex-sparing Mastectomy After Primary Chemotherapy: A Propensity Score-matched Study.

scientific article published on 24 December 2016

Everolimus and temsirolimus are not the same second-line in metastatic renal cell carcinoma. A systematic review and meta-analysis of literature data

scientific article

Evolution in the treatment of gastroenteropancreatic-neuroendocrine neoplasms, focus on systemic therapeutic options: a systematic review.

scientific article published on July 2015

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

scientific article

Experience with sorafenib in the treatment of advanced renal cell carcinoma.

scientific article

Exposure to Multiple Lines of Treatment and Survival of Patients With Metastatic Renal Cell Carcinoma: A Real-world Analysis.

scientific article published on 5 February 2018

Expression of gemcitabine- and cisplatin-related genes in non-small-cell lung cancer.

scientific article

Expression of the T1 (CD5, p67) surface antigen in B-CLL and B-NHL and its correlation with other B-cell differentiation markers

scientific article published on 01 July 1986

Extended pneumonectomy with partial resection of the left atrium, without cardiopulmonary bypass, for lung cancer.

scientific article

FOLFIRI with cetuximab or bevacizumab: FIRE-3

scientific article published on 24 November 2014

FOLFOX-4 chemotherapy for patients with unresectable or relapsed peritoneal pseudomyxoma

scientific article

Factor v leiden mutation in patients with breast cancer with a central venous catheter: risk of deep vein thrombosis

scientific article published on 01 January 2006

Fatal case of hepatic portal venous gas following palliative stenting and chemotherapy for occlusive advanced colorectal cancer

Features and prognostic factors of large node-negative non-small-cell lung cancers shifted to stage II.

scientific article published in July 2012

First clinical experience of orally active epidermal growth factor receptor inhibitor combined with simplified FOLFOX6 as first-line treatment for metastatic colorectal cancer

scientific article published on 01 August 2007

First line treatment of metastatic renal cell carcinoma: two standards with different toxicity profile

scientific article

First-line anti-EGFR monoclonal antibodies in panRAS wild-type metastatic colorectal cancer: A systematic review and meta-analysis

scientific article published on 5 June 2015

Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer

scientific article

GNAS mutations as prognostic biomarker in patients with relapsed peritoneal pseudomyxoma receiving metronomic capecitabine and bevacizumab: a clinical and translational study

scientific article published on 6 May 2016

Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status

scientific article

Gastric cancer

scientific article published on 20 February 2009

Gastric cancer

scientific article published on 01 June 2005

Gastric cancer

scientific article published on 01 February 1998

Gastrointestinal stromal tumors: should they be treated with the same systemic chemotherapy as other soft tissue sarcomas?

scientific article

Gefitinib combined with endocrine manipulation in patients with hormone-refractory prostate cancer: quality of life and surrogate markers of activity

scientific article

Gemcitabine and pemetrexed combination: the key role of the sequence of drugs administration

scientific article published on 18 August 2009

Gemcitabine-induced systemic capillary leak syndrome

scientific article published in November 2001

HER2 loss in HER2-positive gastric or gastroesophageal cancer after trastuzumab therapy: Implication for further clinical research.

scientific article published on 31 August 2016

HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature.

scientific article published on 9 December 2016

HSPH1 inhibition downregulates Bcl-6 and c-Myc and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma.

scientific article

Health-related quality of life impact in a randomised phase III study of the combination of dabrafenib and trametinib versus dabrafenib monotherapy in patients with BRAF V600 metastatic melanoma

scientific article published on 17 March 2015

Health-related quality of life in patients with hormone refractory prostate cancer receiving gefitinib.

scientific article published on 19 March 2009

Heterogeneity of Acquired Resistance to Anti-EGFR Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.

scientific article published on 25 October 2016

Highlights from the ASCO Genitourinary Symposium 2014: focus on renal and prostate cancer

scientific article published on 27 August 2014

How do the results of the RADIANT trials impact on the management of NET patients? A systematic review of published studies

scientific article

Hyperfractionated radiotherapy in locally advanced nasopharyngeal cancer. An analysis of 43 consecutive patients

scientific article published on 01 July 2004

IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients

scientific article published on 25 January 2017

Ifosfamide in the elderly: clinical considerations for a better drug management.

scientific article

Imatinib administration in two patients with liver metastases from GIST and severe jaundice

scientific article published on October 2003

Immune Suppression and Response to Ipilimumab: Assessing Risk-to-Benefit Ratio

scientific article published on 19 January 2016

Immunohistochemical detection of HER1/HER2 can be considered a predictive marker of gefitinib activity in non-small-cell lung cancer?

scientific article published in February 2005

Immunohistochemistry to enhance prognostic allocation and guide decision-making of patients with advanced urothelial cancer receiving first-line chemotherapy

scientific article published on 08 August 2014

Immunotherapy advances in uro-genital malignancies

scientific article

Improved health perception after genetic counselling for women at high risk of breast and/or ovarian cancer: construction of new questionnaires--an Italian exploratory study

scientific article published on 17 November 2015

Improved quality of life is the way to longer life

scientific article published on 06 June 2016

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.

scientific article published on 25 July 2006

Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.

scientific article published on 29 November 2017

Incidence and relative risk of grade 3 and 4 diarrhoea in patients treated with capecitabine or 5-fluorouracil: a meta-analysis of published trials

scientific article

Incidence of venous thromboembolism in breast cancer patients during chemotherapy with vinorelbine, cisplatin, 5-fluorouracil as continuous infusion (ViFuP regimen): Is prophylaxis required?

scientific article published on 01 January 2000

Inhibition of the VEGF/VEGFR pathway improves survival in advanced kidney cancer: a systematic review and meta-analysis

scientific article

Is a dexamethasone-sparing strategy capable of preventing acute and delayed emesis caused by combined doxorubicin and paclitaxel for breast cancer? Analysis of a phase II trial

scientific article published on 22 May 2013

Is the standardized uptake value of FDG-PET/CT predictive of pathological complete response in locally advanced rectal cancer treated with capecitabine-based neoadjuvant chemoradiation?

scientific article published on 15 January 2013

Lack of Bax expression is associated with irinotecan-based treatment activity in advanced colorectal cancer patients.

scientific article published on 21 November 2012

Lanreotide autogel every 6 weeks compared with Lanreotide microparticles every 3 weeks in patients with well differentiated neuroendocrine tumors: a Phase III Study

scientific article published in November 2006

Lessons from the ("Iressa" Expanded Access Programme: gefitinib in special non-small-cell lung cancer patient populations.

scientific article published on December 2003

Life-threatening toxic epidermal necrolysis during voriconazole therapy for invasive aspergillosis after chemotherapy

scientific article published on 12 January 2006

Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.

scientific article published on 5 July 2016

Long-term efficacy and safety outcomes of modified (simplified) MVAC (methotrexate/vinblastine/doxorubicin/cisplatin) as frontline therapy for unresectable or metastatic urothelial cancer

scientific article

Long-term, totally implantable central venous access ports connected to a Groshong catheter for chemotherapy of solid tumours: experience from 178 cases using a single type of device

scientific article

Loss of succinate dehydrogenase subunit B (SDHB) as a prognostic factor in advanced ileal well-differentiated neuroendocrine tumors.

scientific article published on 30 November 2016

Lymphoma Immunotherapy: Current Status

scientific article

MET-Driven Resistance to Dual EGFR and BRAF Blockade May Be Overcome by Switching from EGFR to MET Inhibition in BRAF-Mutated Colorectal Cancer.

scientific article

Malignant melanoma

scientific article published on 01 July 2003

Metastatic and locally advanced pancreatic endocrine carcinomas: analysis of factors associated with disease progression.

scientific article published on 9 May 2011

Metformin Use Is Associated With Longer Progression-Free Survival of Patients With Diabetes and Pancreatic Neuroendocrine Tumors Receiving Everolimus and/or Somatostatin Analogues

scientific article published on 13 April 2018

Metformin with everolimus and octreotide in pancreatic neuroendocrine tumor patients with diabetes

scientific article published on 18 February 2016

Modulation of Epidermal Growth Factor Receptor Status by Chemotherapy in Patients With Locally Advanced Non–Small-Cell Lung Cancer Is Rare

scientific article published on 01 December 2004

Molecular Signature of Response to Pazopanib Salvage Therapy for Urothelial Carcinoma.

scientific article published on 7 August 2015

Multiparametric molecular characterization of pulmonary sarcomatoid carcinoma reveals a nonrandom amplification of anaplastic lymphoma kinase (ALK) gene.

scientific article

Neoadjuvant Chemotherapy Exerts Selection Pressure Towards Luminal Phenotype Breast Cancer.

scientific article published on 12 December 2017

Neuroendocrine tumour arising inside a retro-rectal tailgut cyst: report of two cases and a review of the literature.

scientific article published on 22 February 2011

New perspectives in advanced genitourinary malignancies

scientific article published on March 2012

Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial

scientific article

Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial

scientific article

Oligometastatic non-small cell lung cancer: a multidisciplinary approach in the positron emission tomographic scan era.

scientific article published in January 2007

Optimization of the schedule of gemcitabine-cisplatin combination as induction regimen for patients with biopsy-proven stage IIIa N2 - stage IIIb non-small-cell lung cancer: a prospective phase-II study.

scientific article published in September 2004

Optimizing clinical care in patients with advanced soft tissue sarcoma: a phase II study of a new schedule of high-dose continuous infusion ifosfamide and doxorubicin combination.

scientific article

Optimizing pemetrexed-gemcitabine combination in patients with advanced non-small cell lung cancer: a pharmacogenetic approach.

scientific article published in April 2011

Oral administration of vinorelbine can overcome intractable endovenous-vinorelbine-associated acute tumor pain.

scientific article

Osteopontin, E-cadherin, and β-catenin expression as prognostic biomarkers in patients with radically resected gastric cancer.

scientific article published on 11 April 2015

Outcome of Patients with Renal Cell Carcinoma and Multiple Glandular Metastases Treated with Targeted Agents.

scientific article published on 17 February 2017

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

scientific article published on 14 December 2015

Oxaliplatin added to 5-fluorouracil-based therapy (5-FU +/- FA) in the treatment of 5-FU-pretreated patients with advanced colorectal carcinoma (ACRC): results from the European compassionate-use program.

scientific article

Oxaliplatin as single agent in previously untreated colorectal carcinoma patients: A phase II multicentric study

scientific article published on 01 January 1998

PF-03446962, a fully-human monoclonal antibody against transforming growth-factor β (TGFβ) receptor ALK1, in pre-treated patients with urothelial cancer: an open label, single-group, phase 2 trial.

scientific article

Palonosetron: an evidence-based choice in prevention of nausea and vomiting induced by moderately emetogenic chemotherapy

scientific article published on May 2012

Pancreatic well-differentiated neuroendocrine neoplasms (pWDNENs): what place for everolimus and sunitinib derived from ESMO clinical practice guidelines in the therapeutic algorithm?

scientific article published on 13 March 2013

Participation in clinical trials as viewed by the patient: understanding cultural and emotional aspects which influence choice.

scientific article published on 20 August 2008

Pathological response after neoadjuvant bevacizumab- or cetuximab-based chemotherapy in resected colorectal cancer liver metastases

article

Patient approach in advanced/metastatic renal cell carcinoma: focus on the elderly population and treatment-related toxicity

scientific article

Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial.

scientific article published on 20 July 2012

Peptide receptor radionuclide therapy: focus on bronchial neuroendocrine tumors.

scientific article

Perioperative Triplet Chemotherapy and Cetuximab in Patients With RAS Wild Type High Recurrence Risk or Borderline Resectable Colorectal Cancer Liver Metastases

scientific article published on 06 October 2016

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

scientific article

Pharmacogenetics and proteomics of anticancer drugs in non-Hodgkin's lymphoma.

scientific article published on January 2003

Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours.

scientific article published on 4 May 2009

Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer.

scientific article

Phase I study of PF-03446962, a fully human monoclonal antibody against activin receptor-like kinase-1, in patients with hepatocellular carcinoma.

scientific article

Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden

scientific article published on September 1997

Phase I/II study of the tumour-targeting human monoclonal antibody-cytokine fusion protein L19-TNF in patients with advanced solid tumours

scientific article

Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors

scientific article (publication date: November 2014)

Phase II Study of the Etoposide, Leucovorin and Fluorouracil Combination for Patients with Advanced Gastric Cancer Unsuitable for Aggressive Chemotherapy

scientific article published on 01 January 1995

Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma.

scientific article

Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma

scientific article published on 20 April 2010

Phase II trial of estramustine phosphate and oral etoposide in patients with hormone-refractory prostate cancer.

scientific article published on 12 January 2009

Phase II trial of vinorelbine, cisplatin and continuous infusion of 5-fluorouracil followed by hyperfractionated radiotherapy in locally advanced head and neck cancer

scientific article published on January 2002

Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate

scientific article published on 14 August 2007

Phase III Trial of Capecitabine Plus Oxaliplatin As Adjuvant Therapy for Stage III Colon Cancer: A Planned Safety Analysis in 1,864 Patients

article

Phase ib of sorafenib in combination with everolimus in patients with advanced solid tumors, selected on the basis of molecular targets.

scientific article published on 27 March 2014

Pitfalls in oncology: a unique case of thoracic splenosis mimicking malignancy in a patient with resected breast cancer

scientific article

Platinum salts in advanced breast cancer: a systematic review and meta-analysis of randomized clinical trials.

scientific article

Practical considerations in the treatment of hepatocellular carcinoma.

scientific article published on March 1998

Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: a meta-analysis

scientific article

Predictive testing for DPD deficiency in a patient with familial history of fluoropyrimidine-associated toxicity

scientific article published on 24 February 2014

Preoperative Capecitabine, Oxaliplatin, and Irinotecan in Resectable Gastric or Gastroesophageal Junction Cancer: Pathological Response as Primary Endpoint and FDG-PET Predictions

scientific article published on 8 September 2017

Preoperative chemotherapy is essential for conservative surgery of Askin tumors.

scientific article published in February 2003

Preoperative versus postoperative docetaxel-cisplatin-fluorouracil (TCF) chemotherapy in locally advanced resectable gastric carcinoma: 10-year follow-up of the SAKK 43/99 phase III trial.

scientific article

Primary Cerebellar Neuroendocrine Tumors: Chimeras or Real Entities? A Case Report with a 6-Year Follow-Up.

scientific article published on May 2016

Primary chemotherapy in operable breast cancer with favorable prognostic factors: a pilot study evaluating the efficacy of a regimen with a low subjective toxic burden containing vinorelbine, 5-fluorouracil and folinic acid (FLN)

scientific article published on 01 August 1999

Primary cross-resistance to BRAFV600E-, MEK1/2- and PI3K/mTOR-specific inhibitors in BRAF-mutant melanoma cells counteracted by dual pathway blockade

scientific article

Primary tumour resection may improve survival in functional well-differentiated neuroendocrine tumours metastatic to the liver.

scientific article

Prognosis of women with early breast cancer and PIK3CA mutations.

scientific article

Prognostic factors for survival in patients with metastatic renal cell carcinoma treated with targeted therapies.

scientific article

Prognostic impact of the cumulative dose and dose intensity of everolimus in patients with pancreatic neuroendocrine tumors.

scientific article published on 25 May 2017

Prognostic reclassification of patients with intermediate-risk metastatic germ cell tumors: Implications for clinical practice, trial design, and molecular interrogation

scientific article published on 16 May 2015

Prognostic role of pancreatic metastases from renal cell carcinoma: results from an Italian center

scientific article published on 20 June 2013

Prognostic value of diffuse versus intestinal histotype in patients with gastric cancer: a systematic review and meta-analysis.

scientific article

Prophylaxis for venous thromboembolism in cancer patients with a central vein catheter: new tones for an old song.

scientific article published in October 2005

Radiotherapy or chemotherapy for clinical stage IIA and IIB seminoma: a systematic review and meta-analysis of patient outcomes

scientific article published on 11 September 2014

Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer

scientific article

Rationale and protocol of MetNET-2 trial: Lanreotide Autogel plus metformin in advanced gastrointestinal or lung neuroendocrine tumors

scientific article published on 05 June 2017

Rationale and protocol of SOAP: a phase II study to evaluate the efficacy of sorafenib as second-line treatment after pazopanib in patients with advanced renal cell carcinoma

scientific article published on November 2014

Rationale and protocol of the MetNET-1 trial, a prospective, single center, phase II study to evaluate the activity and safety of everolimus in combination with octreotide LAR and metformin in patients with advanced pancreatic neuroendocrine tumors.

scientific article published in November 2014

Re: Adjuvant Treatment of High-Risk, Radically Resected Gastric Cancer Patients with 5-Fluorouracil, Leucovorin, Cisplatin, and Epidoxorubicin in a Randomized Controlled Trial

scientific article published on 28 August 2007

Re: Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer

scientific article

Re: Camillo Porta, Emiliano Calvo, Miguel A. Climent, et al. Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial. Eur Urol 2012

scientific article

Real-world study of everolimus in advanced progressive neuroendocrine tumors

scientific article

Receptor-mediated radiotherapy with 90Y-DOTA-D-Phe1-Tyr3-octreotide

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Recognizing features that are dissimilar in male and female breast cancer: expression of p21Waf1 and p27Kip1 using an immunohistochemical assay

scientific article published on 01 June 2002

Rectal cancer

scientific article published on 06 December 2008

Reply to FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer-subgroup analysis of patients with KRAS-mutated tumours in the randomised German AIO study KRK-0306

scientific article published on 08 August 2012

Reply to the article “Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity” by V. R. Rozados et al. (Ann Oncol 2004; 15: 1543–1550): … and in humans?

scientific article published on 16 February 2005

Respiratory function changes after chemotherapy: an additional risk for postoperative respiratory complications?

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Right pelvic mass in a patient with a radically resected carcinoid of the appendix

scientific article published on 01 September 2009

Risk factors for disease progression in advanced jejunoileal neuroendocrine tumors.

scientific article published on 28 December 2011

Role of BAX for outcome prediction in gastrointestinal malignancies.

scientific article published on 23 May 2013

Role of cMET in the development and progression of colorectal cancer

scientific article published on 03 September 2013

START: a European state-of-the-art on-line instrument for clinical oncologists.

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Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1).

scientific article published on 9 February 2017

Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer: Results from the Phase II BASALT-1 Study

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Safety of Abiraterone Acetate in Castration-resistant Prostate Cancer Patients With Concomitant Cardiovascular Risk Factors

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Safety of long-term exposure to abiraterone acetate in patients with castration-resistant prostate cancer and concomitant cardiovascular risk factors

scientific article published on 5 July 2016

Safety profile and treatment response of everolimus in different solid tumors: an observational study

scientific article published on January 2014

Safety, tolerability and biological effects of long-term metronomic administration of non-cytotoxic anti-angiogenic agents

scientific article published in January 2009

Salvage treatment after r-interferon alpha-2a in advanced neuroendocrine tumors.

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Second-line angiogenesis inhibition in metastatic colorectal cancer patients: Straightforward or overcrowded?

scientific article published on 12 February 2016

Should clinicians always administer dexamethasone beyond 24 h after chemotherapy to control delayed nausea and vomiting caused by moderately emetogenic regimens? Insight from the re-evaluation of two randomized studies

scientific article published on 6 August 2015

Simplified FOLFIRI in pre-treated patients with metastatic gastric cancer

scientific article published on 26 November 2008

Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: Clinical outcome and biomarkers of efficacy

scientific article published on 04 September 2013

Single-Agent Panitumumab in Frail Elderly Patients With Advanced RAS and BRAF Wild-Type Colorectal Cancer: Challenging Drug Label to Light Up New Hope

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Sites of disease as predictors of outcome in metastatic renal cell carcinoma patients treated with first-line sunitinib or sorafenib

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Small-Cell Lung Cancer: Clinical Management and Unmet Needs New Perspectives for an Old Problem.

scientific article published on 2 May 2016

Study design and clinical evidence in mRCC: can we save axitinib as a first-line therapy?

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Successful chemotherapy and 90Y-DOTATOC in a patient with mediastinal highly aggressive neuroendocrine carcinoma.

scientific article

Succinate dehydrogenase B subunit immunohistochemical expression predicts aggressiveness in well differentiated neuroendocrine tumors of the ileum

scientific article published on 16 August 2012

Synergistic activity of oxaliplatin and 5-fluorouracil in patients with metastatic colorectal cancer with progressive disease while on or after 5-fluorouracil

scientific article published on 01 June 1998

Systemic Effects of Surgery: Quantitative Analysis of Circulating Basic Fibroblast Growth Factor (bFGF), Vascular Endothelial Growth Factor (VEGF) and Transforming Growth Factor Beta (TGF-β) in Patients with Breast Cancer Who Underwent Limited or Ex

article

Systemic approach to malignant pleural mesothelioma: what news of chemotherapy, targeted agents and immunotherapy?

scientific article

TP53 mutations in advanced colorectal cancer: the dark side of the moon.

scientific article published on 07 June 2014

Tackling Off-Label Use of Anticancer Drugs

scientific article published on 02 July 2012

Target-Treatment and Patients' Selection: Can We Still Neglect the Timing of Tissue Collection?

scientific article published on 01 September 2005

Targeted therapies and survival: what we can learn from studies in advanced renal cell carcinoma

scientific article published on 17 October 2012

Targeted therapies in advanced renal cell carcinoma: the role of metastatic sites as a prognostic factor

scientific article published on June 2014

Targeted treatments in advanced renal cell carcinoma: focus on axitinib.

scientific article

Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions

scientific article published on 21 November 2016

Targeting the MET gene for the treatment of non-small-cell lung cancer

scientific article published on December 2013

The Long-Term Benefit of Liver Transplantation for Hepatic Metastases From Neuroendocrine Tumors

scientific article published on 09 June 2016

The biological basis for antiangiogenic therapy

scientific article published on 01 October 2000

The choice of whether to participate in a phase I clinical trial: increasing the awareness of patients with cancer. An exploratory study

scientific article published on 10 October 2013

The tumour-targeting human L19-IL2 immunocytokine: preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma.

scientific article published on 24 August 2010

The underestimated role of somatostatin analogs in the NETTER-1 trial

scientific article published on 11 May 2017

Three-times daily radiotherapy after chemotherapy in stage III non-small cell lung cancer. Single-institution prospective study

scientific article published in November 2008

Three-times-daily radiotherapy with induction chemotherapy in locally advanced non-small cell lung cancer. Feasibility and toxicity study

scientific article published in June 2005

Time from Nephrectomy as a Prognostic Factor in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapies: Overall Results from a Large Cohort of Patients

To target or not to target, that is the question.

scientific article

Totally implantable central venous access ports for long-term chemotherapy. A prospective study analyzing complications and costs of 333 devices with a minimum follow-up of 180 days

scientific article published in July 1998

Trabectedin for women with ovarian carcinoma after treatment with platinum and taxanes fails.

scientific article

Trastuzumab cardiac toxicity: a problem we put our heart into

scientific article published on 03 August 2015

Treatment of carcinoid syndrome with recombinant interferon alpha-2a.

scientific article

Treatment of elderly patients with metastatic renal cell carcinoma

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Treatment of lung large cell neuroendocrine carcinoma.

scientific article published on 4 March 2016

Treatment with tandem [90Y]DOTA-TATE and [177Lu]DOTA-TATE of neuroendocrine tumours refractory to conventional therapy

scientific article published on 01 February 2014

Tumour CEA as predictor of better outcome in squamous cell carcinoma of the lung

scientific article published on 23 December 2004

Uncommon mutations in epidermal growth factor receptor and response to first and second generation tyrosine kinase inhibitors: A case series and literature review

scientific article published on 5 December 2017

Uncommon somatic mutations in metastatic NUT midline carcinoma.

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Undetected toxicity risk in pharmacogenetic testing for dihydropyrimidine dehydrogenase

scientific article published on 21 April 2015

Update on medical treatment of small intestinal neuroendocrine tumors

scientific article published on 29 June 2016

Vaccines in non-small cell lung cancer: rationale, combination strategies and update on clinical trials.

scientific article published on 25 February 2012

Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab.

scientific article published on 22 March 2016

Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study.

scientific article

Very low acute toxicity of three fractions per day accelerated radiotherapy given after induction chemotherapy and surgery in stage III non- small cell lung cancer

article

Vinorelbine in BRAF V600E mutated metastatic colorectal cancer: a prospective multicentre phase II clinical study.

scientific article published on 10 August 2017

Waiting for Godot: Predictive factors for adjuvant treatment of patients with luminal breast cancer.

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Well-differentiated neuroendocrine tumor of tailgut cyst. A rare entity with controversial medical opportunities

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miR-9 and miR-200 Regulate PDGFRβ-Mediated Endothelial Differentiation of Tumor Cells in Triple-Negative Breast Cancer.

scientific article published on 11 July 2016

¹⁸F-FLT PET/CT as an imaging tool for early prediction of pathological response in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy: a pilot study.

scientific article published on 12 February 2015

ΔNp63 (p40) distribution inside lung cancer: a driver biomarker approach to tumor characterization

scientific article published on 12 March 2013

“Burned out” phenomenon of the testis in retroperitoneal seminoma

scientific article published on 01 January 2006

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