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List of works by Kylene Kehn-Hall

1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription

scientific article

9-Aminoacridine inhibition of HIV-1 Tat dependent transcription

scientific article

A ΩXaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

scientific article published on 27 April 2015

Ablation of Programmed -1 Ribosomal Frameshifting in Venezuelan Equine Encephalitis Virus Results in Attenuated Neuropathogenicity

scientific article

Absence of DICER in monocytes and its regulation by HIV-1.

scientific article

Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2

scientific article

Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV2–Priming Protease TMPRSS2

scientific article published on 06 May 2020

Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection

scientific article

Alterations in the host transcriptome in vitro following Rift Valley fever virus infection

scientific article published on 30 October 2017

An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy

scientific article published in 2024

Analysis of the roles of HIV-derived microRNAs

scientific article published on January 2011

Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

scientific article published in Scientific Reports

BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection

scientific article

Better understanding and prediction of antiviral peptides through primary and secondary structure feature importance

scientific article published on 06 November 2020

CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing

scientific article

Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case

scientific article

Characterizing the effect of Bortezomib on Rift Valley Fever Virus multiplication

scientific article published on 19 May 2015

Chromatin dynamics associated with HIV-1 Tat-activated transcription

scientific article published on 27 August 2009

Clinical Utility of a Highly Sensitive Lateral Flow Immunoassay as determined by Titer Analysis for the Detection of anti-SARS-CoV-2 Antibodies at the Point-of-Care

scientific article published on 02 August 2020

Combination Kinase Inhibitor Treatment Suppresses Rift Valley Fever Virus Replication

scientific article published on 13 April 2018

Correction: Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining

scientific article published on September 2016

Correction: Phosphoproteomic analysis reveals Smad protein family activation following Rift Valley fever virus infection.

scientific article

Curcumin inhibits Rift Valley fever virus replication in human cells

scientific article published in Journal of Biological Chemistry

Curcumin inhibits Rift Valley fever virus replication in human cells.

scientific article

Cyclin dependent kinases as attractive targets to prevent transcription from viral genomes

scientific article published on January 2009

Design of Potential Bisubstrate Inhibitors against Mycobacterium tuberculosis (Mtb) 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (Dxr)-Evidence of a Novel Binding Mode

scientific article published on July 2013

Detection of Highly Pathogenic Viral Agents

Developments in antivirals against influenza, smallpox and hemorrhagic fever viruses

scientific article published on February 2011

Direct detection of diverse metabolic changes in virally transformed and Tax-expressing cells by mass spectrometry.

scientific article published on 6 June 2011

Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry

scientific article

Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1

scientific article

Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

scientific article

EGR1 upregulation following Venezuelan equine encephalitis virus infection is regulated by ERK and PERK pathways contributing to cell death

scientific article published on 31 October 2019

Effect of transcription peptide inhibitors on HIV-1 replication

scientific article published on 2 May 2008

Enhanced detection of respiratory pathogens with nanotrap particles

scientific article published on 4 May 2016

Erratum to: microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection ⬇️

scientific article published on July 12, 2010

Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA

scientific article

Exosomes derived from HTLV-1 infected cells contain the viral protein Tax.

scientific article

Features of HTLV-1 transcriptional and chromatin remodeling dynamics emerge from ChIP-chip analysis

scientific article

Host-based processes as therapeutic targets for Rift Valley fever virus

scientific article published on 11 October 2018

Human T-Lymphotropic Virus Type 1 transcription and chromatin-remodeling complexes

Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes

scientific article

Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening

scientific article published on 11 January 2018

Identifying membrane protein surface markers of HIV-1 infection

article

Improved plaque assay for human coronaviruses 229E and OC43

scientific article published on 21 December 2020

Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication

scientific article published on 5 January 2012

Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors

scientific article published on 22 April 2011

Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells

scientific article published on 27 September 2014

Inhibition of human immunodeficiency virus type-1 by cdk inhibitors

scientific article

Junin Virus Activates p38 MAPK and HSP27 Upon Entry

scientific article published on 07 April 2022

Lessons from the Ebola Outbreak: Action Items for Emerging Infectious Disease Preparedness and Response

scientific article published on 25 February 2016

Localization and sub-cellular shuttling of HTLV-1 Tax with the RNAi machinery component Drosha.

scientific article

Localization and sub-cellular shuttling of HTLV-1 Tax with the microRNA machinery.

scientific article

Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery

scientific article

Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.

scientific article published on 22 May 2008

Magnetic Nanotrap Particles Preserve the Stability of Venezuelan Equine Encephalitis Virus in Blood for Laboratory Detection

scientific article published on 01 January 2019

Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function

scientific article

Modeling the Tertiary Structure of the Rift Valley Fever Virus L Protein

scientific article published on 07 May 2019

Modulation of GSK-3β activity in Venezuelan equine encephalitis virus infection

scientific article (publication date: 2012)

Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors

scientific article

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining

scientific article

New World alphavirus protein interactomes from a therapeutic perspective

scientific article published on 26 January 2019

Novel HIV-1 therapeutics through targeting altered host cell pathways

scientific article

Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity

Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design.

scientific article published on 18 December 2017

Novel insights into transcriptional elongation: Ubiquitination of HEXIM1 and p-TEFb activity

Novel insights into transcriptional elongation: ubiquitination of HEXIM1 and p-TEFb activity.

scientific article

Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication

scientific article

Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication

scientific article published on 22 October 2013

Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens

scientific article

PSGL-1 Inhibits the Incorporation of SARS-CoV and SARS-CoV-2 Spike Glycoproteins into Pseudovirions and Impairs Pseudovirus Attachment and Infectivity

scientific article published on 30 December 2020

PSGL-1 blocks SARS-CoV-2 S protein-mediated virus attachment and infection of target cells

scientific article published on 03 May 2020

Phloretin Inhibits Zika Virus Infection by Interfering with the Cellular Glucose Utilization

scientific article published on 28 March 2019

Phosphoproteomic analysis reveals Smad protein family activation following Rift Valley fever virus infection

scientific article

Protein Kinase C subtype δ interacts with Venezuelan equine encephalitis virus capsid protein and regulates viral RNA binding through modulation of capsid phosphorylation

scientific article published on 09 March 2020

Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation

scientific article

Protein Phosphatase-1 regulates Rift Valley fever virus replication

scientific article published on 19 January 2016

Proteomic strategies for the discovery of novel diagnostic and therapeutic targets for infectious diseases

scientific article published on 13 March 2014

Rapamycin modulation of p70 S6 kinase signaling inhibits Rift Valley fever virus pathogenesis

scientific article published on 22 April 2017

Rapid, non-targeted discovery of biochemical transformation and biomarker candidates in oncovirus-infected cell lines using LAESI mass spectrometry

scientific article

Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells

scientific article published on 15 December 2013

Repurposed FDA-Approved drug sorafenib reduces replication of Venezuelan equine encephalitis virus and other alphaviruses

scientific article published on 05 July 2018

Repurposing FDA-approved drugs as therapeutics to treat Rift Valley fever virus infection

scientific article published on 8 July 2015

Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication

scientific article published on June 2008

Reverse-phase phosphoproteome analysis (RPMA) of signaling pathways induced by HTLV-1 infection

Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells

scientific article

Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells

scientific article published on 12 February 2015

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells

scientific article

Small molecule inhibitors of Ago2 decrease Venezuelan equine encephalitis virus replication

scientific article published on 18 October 2014

Sorafenib impedes Rift Valley fever virus egress by inhibiting Valosin-containing protein function in the cellular secretory pathway

scientific article published on 09 August 2017

Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design

scientific article published on 11 March 2020

The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner

scientific article

The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients

scientific article

The role of IKKβ in Venezuelan equine encephalitis virus infection

scientific article (publication date: 2014)

The role of signal transducer and activator of transcription 3 in Rift Valley fever virus infection

scientific article published on 16 June 2016

The ubiquitin proteasome system plays a role in venezuelan equine encephalitis virus infection

scientific article

The use of NanoTrap particles as a sample enrichment method to enhance the detection of Rift Valley Fever Virus

scientific article

The use of Nanotrap particles for biodefense and emerging infectious disease diagnostics

scientific article

The use of Nanotrap particles in the enhanced detection of Rift Valley fever virus nucleoprotein

scientific article published on 28 May 2015

The use of Nanotrap particles technology in capturing HIV-1 virions and viral proteins from infected cells

scientific article

The utilization of humanized mouse models for the study of human retroviral infections

scientific article published on 12 August 2009

The utilization of humanized mouse models for the study of inhibitors in HTLV-1 infection.

scientific article

Transcription through the HIV-1 nucleosomes: effects of the PBAF complex in Tat activated transcription

scientific article

Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 Infections

scientific article

Use of ATP analogs to inhibit HIV-1 transcription

scientific article

Use of Nanotrap particles for the capture and enrichment of Zika, chikungunya and dengue viruses in urine

scientific article published on 07 January 2020

Varying modulation of HIV-1 LTR activity by Baf complexes

scientific article

Varying modulation of HTLV-1 LTR activity by BAF complexes.

scientific article published on 6 June 2011

Venezuelan Equine Encephalitis Virus Capsid Implicated in Infection-Induced Cell Cycle Delay

scientific article published in 2018

Venezuelan Equine Encephalitis Virus Capsid-The Clever Caper

scientific article published on 29 September 2017

Venezuelan Equine Encephalitis Virus Induces Apoptosis through the Unfolded Protein Response Activation of EGR1.

scientific article published on 20 January 2016

Viral concentration determination through plaque assays: using traditional and novel overlay systems

scientific article

microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection

scientific article

p53 Activation following Rift Valley fever virus infection contributes to cell death and viral production

scientific article

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