List of works - Mark Gumbleton

2008 Editors' Collection

scientific article published on 06 October 2008

Aberrant caveolin-1 expression in psoriasis: a signalling hypothesis

scientific article

Activated extracellular signal-regulated kinase is an independent prognostic factor in clinically confined renal cell carcinoma

scientific article published on 01 August 2009

An ex vivo investigation into the transurothelial permeability and bladder wall distribution of the nonsteroidal anti-inflammatory ketorolac

scientific article published on 06 February 2014

Auto-fluorescent PAMAM-based dendritic molecules and their potential application in pharmaceutical sciences

scientific article published on 02 March 2020

Caveolae-mediated membrane transport

scientific article published on 01 July 2001

Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function.

scientific article

Caveolin expression during chondrogenesis in the avian limb.

scientific article published in October 2002

Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures

scientific article published on 01 September 1999

Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

scientific article published on 11 October 2013

Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma

scientific article published on November 2003

Cell selective glucocorticoid induction of caveolin-1 and caveolae in differentiating pulmonary alveolar epithelial cell cultures

scientific journal article

Challenges and innovations in effective pulmonary systemic and macromolecular drug delivery

scientific article published on 12 August 2006

Challenges in inhaled product development and opportunities for open innovation

scientific article published on 06 December 2010

Characterization and astrocytic modulation of system L transporters in brain microvasculature endothelial cells

scientific article

Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma.

scientific article

Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures

scientific article

Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C.

scientific article published on 12 November 2002

Downregulation and altered spatial pattern of caveolin-1 in chronic plaque psoriasis

scientific article published on October 2002

Endocytosis at the blood-brain barrier: from basic understanding to drug delivery strategies

scientific article

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies

scientific article published on November 2003

Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro.

scientific article published in December 2000

Expression and transport functionality of FcRn within rat alveolar epithelium: a study in primary cell culture and in the isolated perfused lung

scientific article

Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes

scientific article published in March 2000

Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance.

scientific article published on 15 March 2009

INSIDIA: A FIJI Macro Delivering High-Throughput and High-Content Spheroid Invasion Analysis

scientific article published on 8 August 2017

Identification and biological evaluation of grapefruit oil components as potential novel efflux pump modulators in methicillin-resistant Staphylococcus aureus bacterial strains

scientific article published in November 2004

Improved gas chromatographic assay for the simultaneous determination of nitroglycerin and its mono- and dinitrate metabolites

scientific article published on 01 September 1992

In vivo evaluation of an oral self-emulsifying drug delivery system (SEDDS) for exenatide

scientific article published on 21 March 2018

Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation

scientific article published on 16 July 2012

Lung surfactant phospholipids inhibit the uptake of respirable microspheres by the alveolar macrophage NR8383

scientific article published on 01 August 2002

Maximal extent of translocation of single-walled carbon nanotubes from lung airways of the rat.

scientific article published on 20 February 2013

Methods to determine the interactions of micro- and nanoparticles with mucus.

scientific article

Microcalorimetry does not predict the cellular phagocytosis of latex microspheres

scientific article

Modulation of the fate of zein nanoparticles by their coating with a Gantrez® AN-thiamine polymer conjugate

scientific article published on 25 January 2019

Mucus permeating thiolated self-emulsifying drug delivery systems

scientific article published on 17 November 2015

Nuclear localisation and pDNA condensation in non-viral gene delivery

scientific article published on April 2007

P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers.

scientific article

PGSE-NMR and SANS studies of the interaction of model polymer therapeutics with mucin

scientific article

Pegylation of antimicrobial peptides maintains the active peptide conformation, model membrane interactions, and antimicrobial activity while improving lung tissue biocompatibility following airway delivery.

scientific article

Phage display identification of functional binding peptides against 4-acetamidophenol (Paracetamol): an exemplified approach to target low molecular weight organic molecules

scientific article

Pharmaceutical nanoparticles and the mucin biopolymer barrier

scientific article

Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes

scientific article published in March 2000

Polylysine and polyornithine gene transfer complexes: a study of complex stability and cellular uptake as a basis for their differential in-vitro transfection efficiency

scientific article

Primary porcine brain microvascular endothelial cells: biochemical and functional characterisation as a model for drug transport and targeting.

scientific article

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

scientific article published on May 2009

Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: a study in ex vivo lung models using chemical inhibition and genetic knockout.

scientific article published on 13 May 2013

Spatial expression and functionality of drug transporters in the intact lung: objectives for further research.

scientific article published on 22 September 2010

Stereoselective and concentration-dependent polarized epithelial permeability of a series of phosphoramidate triester prodrugs of d4T: an in vitro study in Caco-2 and Madin-Darby canine kidney cell monolayers.

scientific article published on 13 October 2003

Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro

scientific article published in May 2004

Targeting caveolae for vesicular drug transport.

scientific article

Temporal dependence of ectopeptidase expression in alveolar epithelial cell culture: implications for study of peptide absorption

scientific article published on 01 April 1999

The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary

scientific article published on 12 July 2017

The inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophages

scientific article published on 01 April 2002

The particle has landed--characterizing the fate of inhaled pharmaceuticals

scientific article published on December 2010

Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein

scientific article published on 01 August 1999

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems

scientific article published on 01 November 2003

List of works by Mark Gumbleton

2008 Editors' Collection

Aberrant caveolin-1 expression in psoriasis: a signalling hypothesis

Activated extracellular signal-regulated kinase is an independent prognostic factor in clinically confined renal cell carcinoma

An ex vivo investigation into the transurothelial permeability and bladder wall distribution of the nonsteroidal anti-inflammatory ketorolac

Auto-fluorescent PAMAM-based dendritic molecules and their potential application in pharmaceutical sciences

Caveolae-mediated membrane transport

Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function.

Caveolin expression during chondrogenesis in the avian limb.

Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures

Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma

Cell selective glucocorticoid induction of caveolin-1 and caveolae in differentiating pulmonary alveolar epithelial cell cultures

Challenges and innovations in effective pulmonary systemic and macromolecular drug delivery

Challenges in inhaled product development and opportunities for open innovation

Characterization and astrocytic modulation of system L transporters in brain microvasculature endothelial cells

Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma.

Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures

Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C.

Downregulation and altered spatial pattern of caveolin-1 in chronic plaque psoriasis

Endocytosis at the blood-brain barrier: from basic understanding to drug delivery strategies

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies

Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro.

Expression and transport functionality of FcRn within rat alveolar epithelium: a study in primary cell culture and in the isolated perfused lung

Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes

Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance.

INSIDIA: A FIJI Macro Delivering High-Throughput and High-Content Spheroid Invasion Analysis

Identification and biological evaluation of grapefruit oil components as potential novel efflux pump modulators in methicillin-resistant Staphylococcus aureus bacterial strains

Improved gas chromatographic assay for the simultaneous determination of nitroglycerin and its mono- and dinitrate metabolites

In vivo evaluation of an oral self-emulsifying drug delivery system (SEDDS) for exenatide

Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation

Lung surfactant phospholipids inhibit the uptake of respirable microspheres by the alveolar macrophage NR8383

Maximal extent of translocation of single-walled carbon nanotubes from lung airways of the rat.

Methods to determine the interactions of micro- and nanoparticles with mucus.

Microcalorimetry does not predict the cellular phagocytosis of latex microspheres

Modulation of the fate of zein nanoparticles by their coating with a Gantrez® AN-thiamine polymer conjugate

Mucus permeating thiolated self-emulsifying drug delivery systems

Nuclear localisation and pDNA condensation in non-viral gene delivery

P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers.

PGSE-NMR and SANS studies of the interaction of model polymer therapeutics with mucin

Pegylation of antimicrobial peptides maintains the active peptide conformation, model membrane interactions, and antimicrobial activity while improving lung tissue biocompatibility following airway delivery.

Phage display identification of functional binding peptides against 4-acetamidophenol (Paracetamol): an exemplified approach to target low molecular weight organic molecules

Pharmaceutical nanoparticles and the mucin biopolymer barrier

Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes

Polylysine and polyornithine gene transfer complexes: a study of complex stability and cellular uptake as a basis for their differential in-vitro transfection efficiency

Primary porcine brain microvascular endothelial cells: biochemical and functional characterisation as a model for drug transport and targeting.

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: a study in ex vivo lung models using chemical inhibition and genetic knockout.

Spatial expression and functionality of drug transporters in the intact lung: objectives for further research.

Stereoselective and concentration-dependent polarized epithelial permeability of a series of phosphoramidate triester prodrugs of d4T: an in vitro study in Caco-2 and Madin-Darby canine kidney cell monolayers.

Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro

Targeting caveolae for vesicular drug transport.

Temporal dependence of ectopeptidase expression in alveolar epithelial cell culture: implications for study of peptide absorption

The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary

The inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophages

The particle has landed--characterizing the fate of inhaled pharmaceuticals

Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems