List of works - Pedro R Cutillas

Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

scientific article published on 01 April 2021

Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence

scientific article published on 17 September 2021

Application of proteomic techniques to the study of urine and renal tissue ⬇️

scientific article published on October 22, 2008

Cancer associated fibroblast FAK regulates malignant cell metabolism

scientific article published on 10 March 2020

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1.

scientific article published on 10 July 2017

Characterization of a TiO₂ enrichment method for label-free quantitative phosphoproteomics.

scientific article published on 18 February 2011

Clinical urinary peptidomics: learning to walk before we can run.

scientific article published in March 2007

Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome

scientific article

Current challenges in software solutions for mass spectrometry-based quantitative proteomics

scientific article

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.

scientific article published on 26 October 2016

Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

scientific article published on 25 March 2021

Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration

scientific article published on 02 December 2019

Empirical inference of circuitry and plasticity in a kinase signaling network

scientific article published on 9 June 2015

Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

scholarly article published in Nature Cell Biology

Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer.

scientific article published on 7 March 2018

Global profiling of protein kinase activities in cancer cells by mass spectrometry

scientific article

Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets

scientific article

Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation

scientific article published on 22 December 2014

Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells.

scientific article published on 26 March 2013

Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

scientific article

Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance.

scientific article published on 29 April 2012

Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors

scientific article

Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth

scientific article

Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells.

scientific article published on 7 April 2018

Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring

scientific article published on 20 January 2020

Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage

scientific article

The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

scientific article published on 27 February 2016

The urinary proteome and metabonome differ from normal in adults with mitochondrial disease

article

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

scientific article published on 22 July 2020

Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry

scholarly article

Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells

scientific article published on 06 September 2020

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

scientific article

List of works by Pedro R Cutillas

Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence

Application of proteomic techniques to the study of urine and renal tissue ⬇️

Cancer associated fibroblast FAK regulates malignant cell metabolism

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1.

Characterization of a TiO₂ enrichment method for label-free quantitative phosphoproteomics.

Clinical urinary peptidomics: learning to walk before we can run.

Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome

Current challenges in software solutions for mass spectrometry-based quantitative proteomics

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.

Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration

Empirical inference of circuitry and plasticity in a kinase signaling network

Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer.

Global profiling of protein kinase activities in cancer cells by mass spectrometry

Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets

Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation

Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells.

Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance.

Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors

Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth

Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells.

Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring

Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage

The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

The urinary proteome and metabonome differ from normal in adults with mitochondrial disease

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry

Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype