Search filters

List of works by Malgorzata Czyz

17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-κB) Activity in Patient-Derived Melanoma Cell Lines

scientific article published on 26 May 2020

17-Aminogeldanamycin selectively diminishes IRE1α-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes

scientific article published on 01 August 2019

A non-apoptotic function of caspase-3 in pharmacologically-induced differentiation of K562 cells.

scientific article published on 20 July 2009

Accumulation of gamma-globin mRNA and induction of irreversible erythroid differentiation after treatment of CML cell line K562 with new doxorubicin derivatives

scientific article published on 04 October 2006

Actinomycin D specifically inhibits the interaction between transcription factor Sp1 and its binding site

scientific article published in January 1998

Anti-apoptotic proteins on guard of melanoma cell survival

scientific article published on 20 January 2013

Aspirin--the prodigious panacea? Molecular mechanisms of the action of acetylsalicylic acid in the organism

scientific article (publication date: 23 March 2005)

Autoregulation of GAL4 transcription is essential for rapid growth of Kluyveromyces lactis on lactose and galactose

scientific article published on September 1993

BCL-w: apoptotic and non-apoptotic role in health and disease

scientific article published on 21 April 2020

BH3 mimetics potentiate pro-apoptotic activity of encorafenib in BRAF<sup>V600E</sup> melanoma cells

scientific article published on 28 November 2020

BRAF mutation in progression and therapy of melanoma, papillary thyroid carcinoma and colorectal adenocarcinoma

scientific article

Biological evaluation of novel Pt(II) and Pd(II) complexes with pyrazole-containing ligands

scientific article

Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells

scientific article published on July 2010

Combined effects of doxorubicin and STI571 on growth, differentiation and apoptosis of CML cell line K562.

scientific article published on 25 October 2007

Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics.

scientific article

Cytotoxic effect, differentiation, inhibition of growth and theoretical calculations of an N,N-donor ligands and its platinum(II), palladium(II) and copper(II) complexes

scientific article published on 10 August 2007

Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities

scientific article

Deciphering the Functional Role of RIPK4 in Melanoma

scientific article published on 25 October 2021

Diminution of miR-340-5p levels is responsible for increased expression of ABCB5 in melanoma cells under oxygen-deprived conditions.

scientific article published on 7 November 2015

Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity

scientific article published on 07 January 2020

Effect of 8-methoxypsoralen and 4,5'-dimethylangelicin on ribonucleic acid synthesis in vitro

scientific article published in May 1988

Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation.

scientific article published on 26 September 2005

Effects of anticancer drugs on transcription factor-DNA interactions.

scientific article

Effects of anticancer drugs on transcription in vitro.

scientific article

Elevated cholesterol reduces acetylsalicylic acid-mediated platelet acetylation

scientific article (publication date: December 2007)

Evaluation of selected angiogenic and inflammatory markers in endometriosis before and after danazol treatment.

scientific article

Evidence of inhibition of DNA methylation by fludarabine

scientific article published on January 2000

Exogenous growth factors bFGF, EGF and HGF do not influence viability and phenotype of V600EBRAF melanoma cells and their response to vemurafenib and trametinib in vitro

scientific article published on 22 August 2017

Expression of miRNAs as Important Element of Melanoma Cell Plasticity in Response to Microenvironmental Stimuli

scientific article published on May 2015

Fibroblast Growth Factor Receptor Signaling in Skin Cancers

scientific article published on 04 June 2019

GATA-1 binding to the alphaV promoter negatively regulates expression of the integrin alphaV subunit in human leukemic K562 cells.

scientific article

Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype

scientific article

HGF/c-MET Signaling in Melanocytes and Melanoma

scientific article published in 2018

Increased protein glycation in diabetes mellitus is associated with decreased aspirin-mediated protein acetylation and reduced sensitivity of blood platelets to aspirin

scientific article (publication date: February 2005)

Induced differentiation of the K562 leukemic cell line

scientific article published in March 2005

Inhibition of DNA-dependent RNA synthesis by 8-methoxypsoralen

scientific article published on 01 September 1988

Inhibition of RNA synthesis in vitro by 9-aminoacridine carboxamide antitumor agents. Effects on overall RNA synthesis and synthesis of the initiating dinucleotide

scientific article

Inhibition of RNA synthesis in vitro by acridines--relation between structure and activity.

scientific article

Inhibitors of HSP90 in melanoma

scientific article published on 01 February 2020

Insulin Reduces the Efficacy of Vemurafenib and Trametinib in Melanoma Cells

scientific article published on 13 August 2020

MCL-1, BCL-XL and MITF Are Diversely Employed in Adaptive Response of Melanoma Cells to Changes in Microenvironment

scientific article published on 2 June 2015

MITF in melanoma: mechanisms behind its expression and activity.

scientific article

Melanoma-Derived Extracellular Vesicles Bear the Potential for the Induction of Antigen-Specific Tolerance

scientific article published on 02 July 2019

MiRNA in melanoma-derived exosomes

scientific article published on 7 February 2014

Modulation of WNT/β-catenin pathway in melanoma by biologically active components derived from plants.

scientific article published on 2 February 2016

Molecular mechanisms of anthracyclines action

scientific article published in January 2006

Molecular mechanisms of parthenolide's action: Old drug with a new face

scientific article published on 16 March 2010

Natural compounds' activity against cancer stem-like or fast-cycling melanoma cells

scientific article

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas.

scientific article published on 27 September 2016

Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies

scientific article published on 14 August 2020

Parthenolide complements the cell death-inducing activity of doxorubicin in melanoma cells

scientific article published on August 2013

Parthenolide enhances dacarbazine activity against melanoma cells

scientific article published on September 2013

Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations

scientific article published on 27 January 2016

Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.

scientific article published on 28 November 2012

Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.

scientific article

Pentoxifylline Inhibits WNT Signalling in β-Cateninhigh Patient-Derived Melanoma Cell Populations

scientific article

Phenotypic diversity of patient-derived melanoma populations in stem cell medium.

scientific article published on 13 April 2015

Physiologically Relevant Oxygen Concentration (6% O2) as an Important Component of the Microenvironment Impacting Melanoma Phenotype and Melanoma Response to Targeted Therapeutics In Vitro ⬇️

scientific article published on 27 August 2019

Plasticity of Drug-Naïve and Vemurafenib- or Trametinib-Resistant Melanoma Cells in Execution of Differentiation/Pigmentation Program

scientific article published on 03 July 2019

Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells

scientific article

Pro-apoptotic activity of BH3-only proteins and BH3 mimetics: from theory to potential cancer therapy

scientific article published on October 2012

Pro-survival role of MITF in melanoma

scientific article

Proteomics in human cancer research

scientific article published on 13 December 2006

Regulation of the Tissue Factor Promoter in Endothelial Cells

scientific article published in Journal of Biological Chemistry

Role of miRNAs in Melanoma Metastasis

scientific article published on 07 March 2019

STI571 and morpholine derivative of doxorubicin collaborate in inhibition of K562 cell proliferation by inducing differentiation and mitochondrial pathway of apoptosis

scientific article published on 30 August 2008

STI571/doxorubicin concentration-dependent switch for diverse caspase actions in CML cell line K562.

scientific article

Selective Sp1 and Sp3 binding is crucial for activity of the integrin alphaV promoter in cultured endothelial cells

scientific article

Sequence specificity of formaldehyde-mediated covalent binding of anthracycline derivatives to DNA.

scientific article published in January 2005

Specificity and selectivity of the NFkappaB response

scientific article published in January 2005

Sphere formation and self-renewal capacity of melanoma cells is affected by the microenvironment

scientific article published on 01 June 2012

Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond

scientific article published on 28 June 2022

Synthesis and biological evaluation of new bischromone derivatives with antiproliferative activity

scientific article

Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs

scientific article published on 29 September 2010

Synthesis, X-ray structure, electrochemical properties and cytotoxic effects of new arene ruthenium(II) complexes

Synthesis, physico-chemical properties and biological analysis of newly obtained copper(II) complexes with pyrazole derivatives

scientific article published on 10 March 2014

Synthesis, structure, electrochemical properties, cytotoxic effects and antioxidant activity of 5-amino-8-methyl-4H-benzopyran-4-one and its copper(II) complexes

scientific article published in January 2012

Synthesis, structure, physico-chemical and biological properties of metal(II) complexes with 5-amino-8-methyl-4H-benzopyran-4-one

scientific article published in January 2014

TGF-β signaling pathways in cancers

scientific article published on 25 September 2013

TYRP1 mRNA level is stable and MITF-M-independent in drug-naïve, vemurafenib- and trametinib-resistant BRAFV600E melanoma cells

scientific article published on 17 October 2019

Targeting NF-κB and HIF-1 pathways for the treatment of cancer: part I.

scientific article published on 28 May 2011

Targeting NF-κB and HIF-1 pathways for the treatment of cancer: part II.

scientific article published on 28 May 2011

Tautomerization of 2-nitroso-N-arylanilines by coordination as N,N'-chelate ligands to rhenium(I) complexes and the anticancer activity of newly synthesized oximine rhenium(I) complexes against human melanoma and leukemia cells in vitro

scientific article published on April 2010

The Functional Role of Long Non-Coding RNAs in Melanoma

scientific article published in 2021

The effect of a platelet cholesterol modulation on the acetylsalicylic acid-mediated blood platelet inhibition in hypercholesterolemic patients

scientific article published on 01 March 2011

The heterogeneous immune microenvironment in breast cancer is affected by hypoxia-related genes

scientific article published on 8 September 2013

The synthesis, lipophilicity and cytotoxic effects of new ruthenium(II) arene complexes with chromone derivatives.

scientific article published on 26 February 2016

Thymosin beta 4 induces the synthesis of plasminogen activator inhibitor 1 in cultured endothelial cells and increases its extracellular expression

scientific article published on 30 October 2003

Transcription factors as targets for DNA-interacting drugs.

scientific article

Transcription factors as targets of anticancer drugs.

scientific article

Vemurafenib and trametinib reduce expression of CTGF and IL-8 in V600EBRAF melanoma cells

scientific article published on 9 January 2017

WNT Signaling in Melanoma

scientific article published on 09 July 2020

Whole-exome sequencing reveals novel genetic variants associated with diverse phenotypes of melanoma cells

scientific article published on 06 January 2019

[BH3 mimetics as a strategy to complement anticancer therapies]

scientific article published on 03 February 2012

[Novel inhibitors of Bcr-Abl]

scientific article published on 01 January 2006

[Psoralens as probes in the study of the structure and function of nucleic acids]

scientific article published on 01 January 1989

[STI571: a summary of targeted therapy]

scientific article published on 01 January 2006

[Superoxide dismutase mimetics: possible clinical applications]

scientific article published on 05 November 2008

[Transcription factors in the development and progression of melanoma]

scientific article published on 15 October 2007

miRNAs in Melanoma: Tumor Suppressors and Oncogenes with Prognostic Potential

scientific article published on 31 August 2016

Paulina is supported by:

About Paulina

Help