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List of works by Nikolai Petrovsky

4-Hydroxydocosahexaenoic acid, a potent peroxisome proliferator-activated receptor gamma agonist alleviates the symptoms of DSS-induced colitis

scientific article published on 10 January 2008

A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice

scientific article published on 29 October 2019

A fresh perspective from immunologists and vaccine researchers: active vaccination strategies to prevent and reverse Alzheimer's disease

scientific article

A gold glyco-nanoparticle carrying a Listeriolysin O peptide and formulated with Advax™ delta inulin adjuvant induces robust T-cell protection against listeria infection

scientific article published on 7 February 2015

A neural network model approach to the study of human TAP transporter

scientific article (publication date: 1999)

A novel hepatitis B vaccine containing Advax™, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing

scientific article published on 7 January 2013

A single immunization with inactivated H1N1 influenza vaccine formulated with delta inulin adjuvant (Advax™) overcomes pregnancy-associated immune suppression and enhances passive neonatal protection

scientific article

A swollen abdomen: Part 1

AFCo1, a meningococcal B-derived cochleate adjuvant, strongly enhances antibody and T-cell immunity against Plasmodium falciparum merozoite surface protein 4 and 5

scientific article published on 27 February 2009

ALMS1 acts as a critical molecular switch that controls Insulin-stimulated glucose transport in adipocytes

Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice.

scientific article published on 20 February 2006

Addison's disease presenting in four adolescents with type 1 diabetes

article published in 2004

Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge

article

Advax delta inulin adjuvant overcomes immune immaturity in neonatal mice thereby allowing single-dose influenza vaccine protection

scientific article

Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines

scientific article published on December 2016

Advax-adjuvanted recombinant protective antigen provides protection against inhalational anthrax that is further enhanced by addition of murabutide adjuvant

scientific article

Advax4 delta inulin combination adjuvant together with ECMX, a fusion construct of three protective mTB antigens, induces a potent Th1 immune response and protects mice against Mycobacterium tuberculosis infection

scientific article published on 22 September 2017

Advax™, a novel microcrystalline polysaccharide particle engineered from delta inulin, provides robust adjuvant potency together with tolerability and safety.

scientific article

Advax™, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses

scientific article

Aldose reductase gene polymorphisms and diabetic retinopathy susceptibility. ⬇️

scientific article

Allergen databases.

scientific article published on November 2003

Alström syndrome: insights into the pathogenesis of metabolic disorders

scientific article published on 07 December 2010

Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules

scientific article published on July 2016

An adjuvanted subunit SARS-CoV-2 spike protein vaccine provides protection against Covid-19 infection and transmission

scientific article published on 23 February 2022

An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous flaviviruses

scientific article

An inactivated cell culture Japanese encephalitis vaccine (JE-ADVAX) formulated with delta inulin adjuvant provides robust heterologous protection against West Nile encephalitis via cross-protective memory B cells and neutralizing antibody

scientific article published on 17 July 2013

Analysis of the hydrolysis of inulin using real time 1H NMR spectroscopy

scientific article published on 10 March 2012

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

scientific article (publication date: 5 December 2002)

Assessment of cardiovascular disease risk factors and diabetes mellitus in Australian prisons: is the prisoner population unhealthier than the rest of the Australian population?

scientific article

Association between erythropoietin gene polymorphisms and diabetic retinopathy

scientific article published in January 2010

Autoimmune Diabetes in the NOD Mouse: An Essential Role of Fas-FasL Signaling in β Cell Apoptosis

article

BBIQ, a pure TLR7 agonist, is an effective influenza vaccine adjuvant

scientific article published on 16 April 2020

BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response

scientific article

Bioinformatic strategies for better understanding of immune function.

scientific article published in January 2003

Bioinformatics for characterisation of allergens, allergenicity and allergic crossreactivity ⬇️

scientific article published on May 1, 2003

Bioinformatics for study of autoimmunity

scientific article published on December 2006

Calcium Signaling As a Therapeutic Target for Liver Steatosis

scientific article published on 05 March 2019

Carbohydrate-based immune adjuvants

scientific article

Challenges in improving influenza vaccine protection in the elderly

scientific article published in January 2011

Chiral Self-Assembly of Designed Amphiphiles: Influences on Aggregate Morphology

scientific article published on 30 July 2013

Circadian rhythmicity of interferon-gamma production in antigen-stimulated whole blood

article

Common Sequence Variation in the VEGFC Gene Is Associated with Diabetic Retinopathy and Diabetic Macular Edema

article

Common sequence variation in the VEGFA gene predicts risk of diabetic retinopathy

scientific article published on 24 June 2009

Comparative Safety of Vaccine Adjuvants: A Summary of Current Evidence and Future Needs

scientific article

Computational immunology: The coming of age.

scientific article

Computational methods for prediction of T-cell epitopes--a framework for modelling, testing, and applications

scientific article

Computational tools for the study of allergens ⬇️

scientific article published on November 1, 2003

Computational vaccinology and the ICoVax 2012 workshop

scientific article published on 8 March 2013

Cytokine-based human whole blood assay for the detection of antigen-reactive T cells

scientific article published on 01 October 1995

Cytokine-related genes identified from the RIKEN full-length mouse cDNA data set

scientific article

DNA prime/protein boost vaccination elicits robust humoral response in rhesus macaques using oligomeric simian immunodeficiency virus envelope and Advax delta inulin adjuvant

scientific article

Danazol in the treatment of a systemic lupus erythematosus (SLE)-like illness associated with deficiency of the fourth component of complement

scientific article published on 01 April 1997

Data Extraction for Improved Prediction Outcomes in Organ Transplantation — A Hybrid Approach

Delta Inulin Adjuvant Enhances Plasmablast Generation, Expression of Activation-Induced Cytidine Deaminase and B-Cell Affinity Maturation in Human Subjects Receiving Seasonal Influenza Vaccine

scientific article

Delta inulin polysaccharide adjuvant enhances the ability of split-virion H5N1 vaccine to protect against lethal challenge in ferrets

scientific article

Delta inulin-based adjuvants promote the generation of polyfunctional CD4+ T cell responses and protection against Mycobacterium tuberculosis infection

scientific article published on 17 August 2017

Delta inulin-derived adjuvants that elicit Th1 phenotype following vaccination reduces respiratory syncytial virus lung titers without a reduction in lung immunopathology

scientific article published on 24 May 2016

Delta inulin: a novel, immunologically active, stable packing structure comprising β-D-[2 -> 1] poly(fructo-furanosyl) α-D-glucose polymers

scientific article

Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes.

scientific article published on 22 May 2019

Development of a SARS Coronavirus Vaccine from Recombinant Spike Protein Plus Delta Inulin Adjuvant

scientific article published on January 2016

Development of a nasal vaccine for chronic hepatitis B infection that uses the ability of hepatitis B core antigen to stimulate a strong Th1 response against hepatitis B surface antigen

scientific article published in October 2004

Dexamethasone infusion testing in the diagnosis of Cushing's syndrome

scientific article

Diabetic retinopathy is associated with elevated serum asymmetric and symmetric dimethylarginines

scientific article published on 12 August 2009

Difficulties and dangers of vaccination strategies for asthma and other autoimmune disorders

scientific article published in October 1994

Diurnal rhythms of pro-inflammatory cytokines: regulation by plasma cortisol and therapeutic implications

scientific article published in April 1998

Doxorubicin-Loaded Delta Inulin Conjugates for Controlled and Targeted Drug Delivery: Development, Characterization, and In Vitro Evaluation

scientific article published on 06 November 2019

Dyspnea in Pulmonary Arterial Hypertension

Editorial (Thematic Issue: The Coming of Age of DNA Vaccines)

scientific article published on 01 January 2014

Efficacy of an Adjuvanted Middle East Respiratory Syndrome Coronavirus Spike Protein Vaccine in Dromedary Camels and Alpacas

scholarly article by Danielle Adney et al published 2 March 2019 in Viruses

Efficient discovery of immune response targets by cyclical refinement of QSAR models of peptide binding.

scientific article published on January 2001

Elevated Lymphocyte Expression of CLIP Is Associated with Type 1 Diabetes and May Be a Useful Marker of Autoimmune Susceptibility

Enhanced pulmonary immunization with aerosolized inactivated influenza vaccine containing delta inulin adjuvant.

scientific article

Evidence for the Viral Aetiology of IDDM

article

Evidence from twins for acquired cellular immune hyperactivity in type 1 diabetes

scientific article published in August 2002

FREP: a database of functional repeats in mouse cDNAs

scientific article

Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis

scientific journal article

Flu watch

Focus on influenza vaccines

scientific article published on 21 October 2009

Freeing vaccine adjuvants from dangerous immunological dogma

scholarly article by Nikolai Petrovsky published February 2008 in Expert Review of Vaccines

Gamma ray sterilization of delta inulin adjuvant particles (Advax™) makes minor, partly reversible structural changes without affecting adjuvant activity.

scientific article

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

scientific article published on 21 March 2016

Genetic study of diabetic retinopathy: recruitment methodology and analysis of baseline characteristics.

scientific article published on 28 October 2013

Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy.

scientific article

Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene

scientific article

HLA Class II-associated polymorphism of interferon-γ production implications for HLA-disease association

article

HLA-matched control subjects are essential in studies of susceptibility to IDDM

scientific article published on 01 January 1995

Human Phase 1 trial of low-dose inactivated seasonal influenza vaccine formulated with Advax™ delta inulin adjuvant

scientific article

Hypothyroidism and hyponatraemia in the hospital setting

scientific article published on 01 April 2005

Identification and characterisation of T-cell epitopes for incorporation into dendritic cell-delivered Listeria vaccines.

scientific article published on 29 May 2015

Identification of "pathologs" (disease-related genes) from the RIKEN mouse cDNA dataset using human curation plus FACTS, a new biological information extraction system

scientific article

Identification of key beta cell gene signaling pathways involved in type 1 diabetes.

scientific article published on December 2004

Immunogenicity and safety of Advax™, a novel polysaccharide adjuvant based on delta inulin, when formulated with hepatitis B surface antigen: a randomized controlled Phase 1 study

scientific article

Immunoinformatics and its relevance to understanding human immune disease

scientific article

Immunoinformatics--the new kid in town.

scientific article published on January 2003

Immunoinformatics-The New Kid in Town

Immunome Research-Five Years On

Immunome research

scientific article

Immunomodulation with microbial vaccines to prevent type 1 diabetes mellitus

scientific article published on March 2010

Immunotherapy – 2076. A controlled study of delta inulin-adjuvanted honey bee venom immunotherapy.

scientific article published on 23 April 2013

Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in pregnant sheep and goats

scientific article published on 12 October 2017

In silico structural homology modelling and docking for assessment of pandemic potential of a novel H7N9 influenza virus and its ability to be neutralized by existing anti-hemagglutinin antibodies.

scientific article

Increased insulin resistance compounded by reduced insulin sensitivity drives the "Fat Aussie" (Alms1foz/foz) model of Alström syndrome towards obesity and type 2 diabetes mellitus.

scientific article published on 16 November 2012

Induction of mucosal and systemic antibody and T-cell responses following prime-boost immunization with novel adjuvanted human immunodeficiency virus-1-vaccine formulations

scientific article

Inferring higher functional information for RIKEN mouse full-length cDNA clones with FACTS

scientific article

Influence of Oxidation Degree on the Physicochemical Properties of Oxidized Inulin

scientific article published on 01 May 2020

Influenza immunization during pregnancy: Benefits for mother and infant

scientific article published on 5 August 2016

Information technologies for vaccine research

scientific article

Inulin crystal initiation via a glucose-fructose cross-link of adjacent polymer chains: atomic force microscopy and static molecular modelling

scientific article

Inulin isoforms differ by repeated additions of one crystal unit cell

scientific article

Inulin-derived adjuvants efficiently promote both Th1 and Th2 immune responses

scientific article

Investigation of the biodistribution, breakdown and excretion of delta inulin adjuvant

scientific article

JE-ADVAX vaccine protection against Japanese encephalitis virus mediated by memory B cells in the absence of CD8(+) T cells and pre-exposure neutralizing antibody

scientific article published on 6 February 2013

Lessons learned from the H1N1 2009 pandemic ⬇️

scientific article published on October 1, 2010

Macrophage Migration Inhibitory Factor (MIF): A Critical Neurohumoral Mediator

article published in 2006

Macrophage migration inhibitory factor exhibits a pronounced circadian rhythm relevant to its role as a glucocorticoid counter-regulator

scientific article published on April 2003

Macrophage migration inhibitory factor: a critical neurohumoral mediator

scientific article

Management of dyspnea in advanced pulmonary arterial hypertension

scientific article published on June 2010

Mechanisms of accelerated immune-mediated diabetes resulting from islet beta cell expression of a Fas ligand transgene

scientific article published in May 2003

Methods for prediction of peptide binding to MHC molecules: a comparative study.

scientific article

Microfluidic formation of core-shell alginate microparticles for protein encapsulation and controlled release

scientific article published on 19 December 2018

Mitochondrial haplogroups are not associated with diabetic retinopathy in a large Australian and British Caucasian sample

scientific article published in Scientific Reports

Molecular Adjuvants for DNA Vaccines

scientific article published on 20 September 2016

Molecular immunology databases and data repositories.

scientific article

Molecular mechanisms for enhanced DNA vaccine immunogenicity.

scientific article

Multistage vaccines containing outer membrane, type III secretion system and inclusion membrane proteins protects against a Chlamydia genital tract infection and pathology

scientific article published on 08 June 2017

Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens

scientific article

Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity

scientific article

Novel nanoparticle vaccines for Listeriosis

scientific article

Observation of the keto tautomer of D-fructose in D(2)O using (1)H NMR spectroscopy

scientific article

P11-21. Induction of persistent mucosal humoral and cellular responses following immunization of mice with HIV-1 envelope protein in inulin-derived adjuvants

scientific article published on 22 October 2009

PRED(TAP): a system for prediction of peptide binding to the human transporter associated with antigen processing

scientific article

PREDNOD, a prediction server for peptide binding to the H-2g7 haplotype of the non-obese diabetic mouse

scientific article published in December 2006

Panblok-H1+advax H1N1/2009pdm vaccine: Insights into rapid development of an delta inulin adjuvanted recombinant pandemic influenza vaccine.

scientific article

Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge

scientific article published on 09 October 2018

Pediatric influenza immunization ⬇️

scientific article published on May 1, 2011

Pharmaceutical and preclinical evaluation of Advax adjuvant as a dose-sparing strategy for ant venom immunotherapy

scientific article published on 09 April 2019

Pharmacological Management of Endocrine Conditions in the Elderly Patient

scholarly article

Physical characterization and in silico modeling of inulin polymer conformation during vaccine adjuvant particle formation

scientific article published on 29 January 2016

Plasmids encoding protein aggregation domains act as molecular adjuvants for DNA vaccines

scientific article published on January 2014

Prediction of novel mouse TLR9 agonists using a random forest approach

scientific article published on 20 December 2019

Prediction of promiscuous peptides that bind HLA class I molecules

scientific article published on June 2002

Pregnancy-associated osteoporosis with hypercalcaemia

scientific article published on 01 September 2002

Prevention of autoimmune diabetes through immunostimulation with Q fever complement-fixing antigen

scientific article published on November 2003

Promoter polymorphism at the tumour necrosis factor/lymphotoxin-alpha locus is associated with type of diabetes but not with susceptibility to sight-threatening diabetic retinopathy

article

Prospects for the prevention and reversal of type 1 diabetes mellitus

scientific article

Proteomic analysis of influenza haemagglutinin-specific antibodies following vaccination reveals convergent immunoglobulin variable region signatures

scientific article published on 6 September 2017

Pulmonary Hypertension in Chronic Lung Diseases and/or Hypoxia

Pushing the frontiers of T-cell vaccines: accurate measurement of human T-cell responses

scientific article

Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax™ polysaccharide adjuvant

scientific article

Rational Structure-Based Drug Design

Relationship between DDAH gene variants and serum ADMA level in individuals with type 1 diabetes.

scientific article published on 20 April 2012

Relationship between peptide selectivities of human transporters associated with antigen processing and HLA class I molecules ⬇️

scientific article published on July 15, 1998

Report from the field: Fifth Vaccine Renaissance in Providence RI.

scientific article

Response of serum macrophage migration inhibitory factor levels to stimulation or suppression of the hypothalamo-pituitary-adrenal axis in normal subjects and patients with Cushing's disease

scientific article

Restricted diversity in the T-cell repertoire

scientific article published in August 1995

Safety and immunogenicity of a delta inulin-adjuvanted inactivated Japanese encephalitis virus vaccine in pregnant mares and foals

scientific article

Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes

scientific article

Serological responses following influenza A H1N1 2009 infection in adults

article

Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology

scientific article

Severe diabetic retinopathy: a rare complication of acromegaly

Severe diabetic retinopathy: a rare complication of acromegaly

scientific article published on 01 January 2002

Sugar-Based Immune Adjuvants for Use in Recombinant, Viral Vector, DNA and Other Styles of Vaccines

Synthesis and Characterization of pH-Sensitive Inulin Conjugate of Isoniazid for Monocyte-Targeted Delivery

scientific article published on 28 October 2019

Systems Immunology, Vaccine Adjuvant

scholarly article published 2013

Technologies for enhanced efficacy of DNA vaccines

scientific article published on February 2012

Temporal regulation of the human immune system

scientific article published in September 2005

Test and teach. Number Fifty-three. Diagnosis: Diabetes-related dyslipidaemia

scientific article

Th1 and Th2: swinging to a hormonal rhythm

scientific article published on 01 December 1995

The Future for Computational Modelling and Prediction Systems in Clinical Immunology

scholarly article by Nikolai Petrovsky et al published 7 October 2008 in Novartis Foundation symposium

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

scientific article

The Safety of an Adjuvanted Autologous Cancer Vaccine Platform in Canine Cancer Patients

scientific article published on 12 October 2018

The Vaccine Renaissance ⬇️

scientific article published on February 1, 2011

The chronobiology of human cytokine production

scientific article published in January 1998

The future for computational modelling and prediction systems in clinical immunology.

scientific article published on January 2003

The future of human DNA vaccines

scientific article

The paradoxical association between immunodeficiency and autoimmunity: Comment on he article by Atkinson

scientific article published on 01 January 1996

The perils of untimed serum cortisol measurement

scientific article

The polysaccharide inulin is characterized by an extensive series of periodic isoforms with varying biological actions

scientific article

The power of an integrated informatic and molecular approach to type 1 diabetes research

scientific article

The role of Fas ligand in beta cell destruction in autoimmune diabetes of NOD mice.

scientific article

The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of beta cell death.

scientific article

The transcriptional landscape of the mammalian genome

scientific article

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

scientific article

The vaccines development forum

article

Towards a unified model of neuroendocrine-immune interaction.

scientific article

Unconventional Vaccines: Progress and Challenges

Use of Artificial Neural Networks in Improving Renal Transplantation Outcomes

scholarly article by Nikolai Petrovsky et al published January 2002 in Graft: organ and cell transplantation

Use of Artificial Neural Networks in the Prediction of Kidney Transplant Outcomes

scholarly article by Fariba Shadabi et al published 2004 in Lecture Notes in Computer Science

Vaccine adjuvant safety: the elephant in the room ⬇️

scientific article published on July 1, 2013

Vaccine adjuvants: current state and future trends

scientific article

Vaccine adjuvants: in search of new paradigms. Interview by Jenaid Rees

scientific article published in July 2013

Vaccine therapies for the prevention of type 1 diabetes mellitus

scientific article

Vaccine-Induced Th1-Type Response Protects against Invasive Group A Streptococcus Infection in the Absence of Opsonizing Antibodies

scientific article published on 10 March 2020

Vaxine

scientific article published on 31 May 2016

Virtual models of the HLA class I antigen processing pathway

scientific article

Whole Blood Assays and the Influence of Circadian Rhythmicity on Human Cytokine Measurement

X-ray crystal structure of rivoglitazone bound to PPARγ and PPAR subtype selectivity of TZDs

scientific article published on 9 May 2017

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