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List of works by Ole Haagen Nielsen

5-Aminosalicylic acid in the treatment of Crohn's disease. A 16-week double-blind, placebo-controlled, multicentre study with Pentasa

scientific article published on 01 September 1987

A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine

scientific article

A randomized controlled trial of the efficacy and safety of CCX282-B, an orally-administered blocker of chemokine receptor CCR9, for patients with Crohn's disease

scientific article

A role for interleukin-33 in T(H)2-polarized intestinal inflammation?

scientific article published on 25 May 2011

ATG16L1: A multifunctional susceptibility factor in Crohn disease

scientific article

Activation of neutrophil chemotaxis by leukotriene B4 and 5-hydroxyeicosatetraenoic acid in chronic inflammatory bowel disease

scientific article published on 01 October 1987

Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis

scientific article published in March 2004

Alpha-1 antitrypsin and granulocyte colony-stimulating factor as serum biomarkers of disease severity in ulcerative colitis

scientific article

Alpha-defensin DEFA1A3 gene copy number elevation in Danish Crohn's disease patients

scientific article published on 24 June 2011

An open prospective study evaluating efficacy and safety of a new medical device for rectal application of activated carbon in the treatment of chronic, uncomplicated perianal fistulas

scientific article

Arachidonic acid and calcium metabolism in rnelittin stimulated neutrophils

scientific article

Arachidonic acid metabolism in neutrophil granulocytes obtained from synovial fluid in rheumatoid arthritis

scientific article published on January 1990

Are NOD2 polymorphisms linked to a specific disease endophenotype of Crohn's disease?

scientific article published on 18 February 2011

Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease

scientific article published on 21 November 2013

Association between Helicobacter pylori infection and ventricular cancer--more than a suspicion. The Danish Society of Gastroenterology

scientific article published in March 2002

Attenuated apoptosis response to Fas-ligand in active ulcerative colitis

scientific article

Biological treatment of Crohn's disease

scientific article

Biologics for Inflammatory Bowel Disease and their Safety in Pregnancy: A Systematic Review and Meta-analysis

scientific article published on 12 September 2020

Biosimilars for Management of Crohn Disease

scientific article published on 11 December 2018

CARD15 Status and Familial Predisposition for Crohn's Disease and Colonic Gene Expression

article

CARD15 single nucleotide polymorphisms 8, 12 and 13 are not increased in ethnic Danes with sarcoidosis

scientific article

COX-2-PGE Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

scientific article published on 03 September 2018

Ca2+ response in neutrophils after exposure to bacterial N-formyl-methionyl-leucyl-phenylalanine: delayed response in ulcerative colitis

scientific article

Caspase 14 does not influence intestinal epithelial cell differentiation

scientific article

Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation

scientific article

Changed colonic profile of P-selectin, platelet-endothelial cell adhesion molecule-1 (PECAM-1), intercellular adhesion molecule-1 (ICAM-1), ICAM-2, and ICAM-3 in inflammatory bowel disease

scientific article published on August 2000

Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis

scientific article published on 23 September 2017

Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies.

scientific article published on 25 April 2018

Chemotactic properties of ICAM-1 and PECAM-1 on neutrophil granulocytes in ulcerative colitis: effects of prednisolone and mesalazine

scientific article

Circulating Cytokines and Cytokine Receptors in Infliximab Treatment Failure Due to TNF-α Independent Crohn Disease

scientific article published on April 2016

Circulating L-selectin levels and endothelial CD34 expression in inflammatory bowel disease

scientific article published on 01 October 1998

Circulating soluble intercellular adhesion molecule-1 (sICAM-1) in active inflammatory bowel disease

scientific article published on 01 September 1994

Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid

scientific article published on 01 May 1990

Collagenous sprue: a coeliac disease look-alike with different treatment strategy.

scientific article

Colonic epithelial cell expression of ICAM-1 relates to loss of surface continuity: a comparative study of inflammatory bowel disease and colonic neoplasms

scientific article published in March 2006

Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel disease

scientific article published on 01 October 2000

Comparative studies of the colonic in situ expression of intercellular adhesion molecules (ICAM-1, -2, and -3), beta2 integrins (LFA-1, Mac-1, and p150,95), and PECAM-1 in ulcerative colitis and Crohn's disease

scientific article published on August 2000

Continuous cytokine exposure of colonic epithelial cells induces DNA damage.

scientific article published on March 2005

Continuous interferon-? or tumor necrosis factor-? exposure of enterocytes attenuates cell death responses

article

Correlation between circulating soluble ICAM-1 and prednisolone-induced amelioration of ulcerative colitis

scientific article published in March 2003

Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease.

scientific article published on 10 March 2017

Cytokines and Organ Failure in Acute Pancreatitis

scientific article published on 01 March 2012

Cytokines in inflammatory bowel disease

scientific article published on November 1, 1992

Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data

scientific article

Digestive Disease Week 2001. Novel therapeutic principles in inflammatory bowel disease. 20-23 May 2001, Atlanta, GA, USA

scientific article published on 01 August 2001

Disease activity in inflammatory bowel disease is associated with increased risk of myocardial infarction, stroke and cardiovascular death--a Danish nationwide cohort study

scientific article

ERK controls epithelial cell death receptor signalling and cellular FLICE-like inhibitory protein (c-FLIP) in ulcerative colitis.

scientific article published on February 2013

Effect of 5-aminosalicylic acid and analogous substances on superoxide generation and intracellular free calcium in human neutrophilic granulocytes

scientific article published on 01 June 1993

Effect of the leukotriene LTD4/LTE4 antagonist, SR 2640, in ulcerative colitis: an open clinical study

scientific article published on 01 March 1991

Effects of antirheumatic drugs on endogenous arachidonate metabolism and chemotaxis in human neutrophil granulocytes

scientific article published on 01 January 1989

Epithelial apoptosis: cause or consequence of ulcerative colitis?

scientific article published in January 2009

Evidence for impaired CARD15 signalling in Crohn's disease without disease linked variants

scientific article

Expression of E-selectin, sialyl Lewis X, and macrophage inflammatory protein-1alpha by colonic epithelial cells in ulcerative colitis

scientific article published on 01 March 1998

Expression of ICAM-1 in colon epithelial cells: an ultrastructural study performed on in vivo and in vitro models

scientific article published on 16 October 2003

Expression of common gamma chain on peripheral blood mononuclear cells in Crohn's disease

scientific article published on 01 February 1997

Expression profiling of apoptosis-related genes in enterocytes isolated from patients with ulcerative colitis

scientific article

Extraintestinal manifestations of inflammatory bowel disease: epidemiology, diagnosis, and management

scientific article

Ex vivo intestinal adhesion of Escherichia coli LF82 in Crohn's disease

scientific article

Favourable effect of TNF-alpha inhibitor (infliximab) on Blau syndrome in monozygotic twins with a de novo CARD15 mutation

scientific article published on December 2006

Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

scientific article published on 27 May 2019

Gastric emptying and subjective symptoms of nausea: lack of effects of a 5-hydroxytryptamine-3 antagonist ondansetron on gastric emptying in patients with gastric stasis syndrome

scientific article published on 01 January 1990

Gastric emptying rate and small bowel transit time in patients with irritable bowel syndrome determined with 99mTc-labeled pellets and scintigraphy

scientific article published on 01 December 1986

Genome-wide gene expression analysis of mucosal colonic biopsies and isolated colonocytes suggests a continuous inflammatory state in the lamina propria of patients with quiescent ulcerative colitis

scientific article published on 01 June 2010

How genetic testing can lead to targeted management of XIAP deficiency-related inflammatory bowel disease.

scientific article

IBD medications during pregnancy and lactation.

scientific article published on 30 July 2013

IBD: Can TNF inhibitors be administered during the third trimester?

scientific article published on 18 December 2012

IL-33 is upregulated in colonocytes of ulcerative colitis.

scientific article published on 11 November 2009

IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis.

scientific article published on 12 August 2014

Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.

scientific article

Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity

scientific article published on 10 March 2020

Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease

scientific article

Impact of feedback and monitoring on colonoscopy withdrawal times and polyp detection rates

scientific article published on June 2017

In vitro Superoxide Production by Peripheral Neutrophils from Patients with Inflammatory Bowel Disease

scientific article published on January 1994

Incidence and prevalence of Crohn's disease in the county of Copenhagen, 1962-87: a sixfold increase in incidence

scientific article published on July 1992

Incidence and prevalence of ulcerative colitis in Copenhagen county from 1962 to 1987.

scientific article published in December 1991

Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study.

scientific article published on 4 February 2016

Increased hepatic urea synthesis in patients with active inflammatory bowel disease

scientific article

Increased numbers of interleukin-15-expressing cells in active ulcerative colitis

scientific article published on 01 September 1996

Increased risk of atrial fibrillation and stroke during active stages of inflammatory bowel disease: a nationwide study

scientific article published on 09 October 2013

Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study.

scientific article published on 7 July 2017

Inflammatory Bowel Disease with Primary Sclerosing Cholangitis: a Danish Population-based Cohort Study 1977-2011.

scientific article published on 10 August 2017

Inflammatory bowel disease is associated with an increased risk of hospitalization for heart failure: a Danish Nationwide Cohort study

scientific article published on 22 July 2014

Inflammatory pathways of importance for management of inflammatory bowel disease

scientific article

Influence of smoking on colonic gene expression profile in Crohn's disease

scientific article

Inhibition of 5-lipoxygenase pathway of arachidonic acid metabolism in human neutrophils by sulfasalazine and 5-aminosalicylic acid.

scientific article

Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation

scientific article published on October 2014

Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

scientific article

Integrative transcriptomic and metabonomic molecular profiling of colonic mucosal biopsies indicates a unique molecular phenotype for ulcerative colitis

scientific article published on 27 October 2014

Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease

scientific article published in July 2001

Interleukin-15 and its role in chronic inflammatory diseases

scientific article published on 01 July 1998

Interleukin-2 receptor alpha and beta chain expression by circulating alpha beta and gamma delta T cells in inflammatory bowel disease

scientific article published on 01 February 1995

Interleukin-4 and 13 induce the expression and release of monocyte chemoattractant protein 1, interleukin-6 and stem cell factor from human detrusor smooth muscle cells: synergy with interleukin-1beta and tumor necrosis factor-alpha.

scientific article published in February 2006

Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier.

scientific article

Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2.

scientific article published on 5 February 2014

Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease.

scientific article published on 02 July 2013

Involvement of oxygen-derived free radicals in the pathogenesis of chronic inflammatory bowel disease ⬇️

scientific article published on December 15, 1991

Iron replacement therapy: do we need new guidelines?

scientific article

LFA-1 subunit expression in ulcerative colitis patients

scientific article published on 01 April 1996

MAP kinases in inflammatory bowel disease

scientific article published on 23 December 2010

Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review

scientific article published on June 2015

Managing vitamin D deficiency in inflammatory bowel disease

scientific article published on 07 January 2019

Mechanisms behind efficacy of tumor necrosis factor inhibitors in inflammatory bowel diseases

scientific article

Mesalamine in the treatment of Crohn disease?

scientific article published in April 2005

Mesalazine for maintenance of medically-induced remission in Crohn disease: a survey of a Cochrane review

scientific article published in August 2005

Metabonomics in Gastroenterology and Hepatology

scientific article published on 25 July 2019

Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology

scientific article published in February 2010

Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals

scientific article

Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

scientific article published on 16 October 2017

Methotrexate for inflammatory bowel disease: time for reconsideration

scientific article published on 21 March 2019

MicroRNAs in inflammatory bowel disease--pathogenesis, diagnostics and therapeutics

scientific article

Microarrays and Crohn's disease: collecting reliable information

scientific article

Microscopic colitis: a missed diagnosis?

scientific article

Mitogen activated protein kinases: a role in inflammatory bowel disease?

scientific article published on 30 September 2009

Mucosal healing in ulcerative colitis: pathophysiology and pharmacology.

scientific article published on January 2013

Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond

scientific article published on 29 December 2012

New strategies for treatment of inflammatory bowel disease

scientific article

Non-IBD and noninfectious colitis.

scientific article published on January 2008

Non-tropical sprue. Malignant diseases and mortality rate

scientific article

Novel Targeted Therapies for Inflammatory Bowel Disease

scientific article published on December 2016

Objective Quantification of Immune Cell Infiltrates and Epidermal Proliferation in Psoriatic Skin: A Comparison of Digital Image Analysis and Manual Counting.

scientific article published on 21 April 2015

Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis.

scientific article published on 07 June 2011

Pediatric tube system for collection of uncontaminated jejunal juice

scientific article published on 01 January 1983

Pharmacology and Optimization of Thiopurines and Methotrexate in Inflammatory Bowel Disease.

scientific article published on 09 August 2015

Pregnancy in ulcerative colitis

scientific article published on 01 September 1983

Prognosis after first-time myocardial infarction in patients with inflammatory bowel disease according to disease activity: nationwide cohort study

scientific article published on 14 October 2014

Proinflammatory cytokines in alcohol or gallstone induced acute pancreatitis. A prospective study.

scientific article

Protective effect of preexisting rotavirus-specific immunoglobulin A against naturally acquired rotavirus infection in children

scientific article published in January 1987

Proximal collagenous gastroenteritides: clinical management. A systematic review.

scientific article published on 10 April 2014

Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD.

scientific article published on 31 May 2018

Quantification of specific E. coli in gut mucosa from Crohn's disease patients

scientific article

Rational Management of Iron-Deficiency Anaemia in Inflammatory Bowel Disease

scientific article published on 13 January 2018

Recent advances using immunomodulators for inflammatory bowel disease

scientific article published on 13 February 2013

Recombinant human tumour necrosis factor increases cytosolic free calcium in murine fibroblasts and stimulates inositol phosphate formation in L-M and arachidonic acid release in 3T3 cells

scientific article published on January 1990

Rectal dialysate and fecal concentrations of neutrophil gelatinase-associated lipocalin, interleukin-8, and tumor necrosis factor-alpha in ulcerative colitis.

scientific article published on October 1999

Regulation of Laminin γ2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation

scientific article published on 23 June 2016

Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

scientific article published on 8 February 2017

Role of Vitamin D in the Natural History of Inflammatory Bowel Disease

scientific article published on 01 May 2018

SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

scientific article published on 18 February 2020

Safety of TNF-α inhibitors during IBD pregnancy: a systematic review

scientific article

Serum Concentration and Chemotactic Activity of E-selectin (CD62E) in Inflammatory Bowel Disease

scientific article published on January 1994

Serum antibodies to Bacteroides species in chronic inflammatory bowel disease

scientific article published on 01 September 1983

Serum antibodies to cow's milk folate-binding protein in patients with chronic inflammatory bowel disease

scientific article published on 01 January 1989

Serum from NSAID-treated patients attenuates the capacity of rat leukocytes to synthesize leukotriene B4

scientific article published on 01 January 1996

Serum interferon activity in inflammatory bowel disease. Arachidonic acid release and lipoxygenation activated by alpha-class interferon in human neutrophils

scientific article published on 01 April 1988

Soluble L-selectin levels predict survival in sepsis

scientific article published on 21 September 2002

Soluble interleukin-2 receptors in ulcerative colitis

scientific article published on January 1993

Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants.

scientific article published on March 2015

Sphingosine-1-Phosphate Signaling in Inflammatory Bowel Disease

scientific article published on 7 March 2017

Spontaneous aggregation of leukocytes in active ulcerative colitis might be ICAM-1 dependent

scientific article published in September 2004

Steady-state kinetics of 5-aminosalicylic acid and sulfapyridine during sulfasalazine prophylaxis in ulcerative colitis

scientific article published on 01 August 1986

Subcellular localization of intercellular adhesion molecule-1 in colonic mucosa in ulcerative colitis

scientific article

Sulfasalazine intolerance. A retrospective survey of the reasons for discontinuing treatment with sulfasalazine in patients with chronic inflammatory bowel disease

scientific article

Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease

scientific article published on 24 October 2019

Systematic review: coxibs, non-steroidal anti-inflammatory drugs or no cyclooxygenase inhibitors in gastroenterological high-risk patients?

scientific article

Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes

scientific article published on 11 December 2015

TNF-α-induced down-regulation of CDX2 suppresses MEP1A expression in colitis

scientific article published on 3 February 2012

Targeting JAK-STAT signal transduction in IBD

scientific article published on 23 July 2018

Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications.

scientific article published on 22 April 2008

Telomere dysfunction activates YAP1 to drive tissue inflammation

scientific article published on 21 September 2020

The antiinflammatory moiety of sulfasalazine, 5-aminosalicylic acid, is a radical scavenger

scientific article published on 01 June 1987

The circulating common gamma chain (CD132) in inflammatory bowel disease

scientific article published on 01 March 1998

The management of iron deficiency in inflammatory bowel disease--an online tool developed by the RAND/UCLA appropriateness method.

scientific article published on 17 September 2013

The role and advances of immunomodulator therapy for inflammatory bowel disease

scientific article published on 07 August 2014

The role of CDX2 in intestinal homeostasis and inflammation

scientific article

The role of cysteinyl leukotrienes in chronic inflammation and neoplasia of the intestine

scientific article published in January 2009

The safety of osmotically acting cathartics in colonic cleansing.

scientific article published on 24 August 2010

The treatment of inflammatory bowel disease with 6‐mercaptopurine or azathioprine ⬇️

scientific article published on November 1, 2001

Tissue-regenerating functions of coagulation factor XIII.

scientific article published on May 2013

Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia

scientific article

Transdermal nicotine treatment of ulcerative colitis: a survey of a Cochrane review

scientific article published in February 2006

Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury

scientific article published on 17 October 2013

Treatment response and colonic gene expression in patients with Crohn's disease

article

Tuft Cells and Their Role in Intestinal Diseases

Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease ⬇️

scientific article published on August 22, 2013

Tumor necrosis factor inhibitors for inflammatory bowel disease.

scientific article

Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis.

scientific article published on 31 October 2007

Use of biological molecules in the treatment of inflammatory bowel disease.

scientific article published on March 2011

Use of thiopurines in inflammatory bowel disease ⬇️

scientific article published on February 21, 2013

Which biological agents are most appropriate for ulcerative colitis?

scientific article published on 01 May 2014

Will novel oral formulations change the management of inflammatory bowel disease?

scientific article published on 11 March 2016

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

scientific article published on 28 November 2017

[Biological drugs in the treatment of immunoinflammatory diseases]

scientific article published on 01 June 2008

miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis ⬇️

scientific article published on July 21, 2013

pcaGoPromoter--an R package for biological and regulatory interpretation of principal components in genome-wide gene expression data

scientific article

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