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List of works by Florian Sennlaub

A regulatory domain is required for Foxn4 activity during retinogenesis

scientific article

ANGPTL4 modulates in vivo developmental and pathological angiogenesis

scholarly article by Elisa Gomez Perdiguero et al published May 2012 in Vascular Pharmacology

APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration

scientific article published on October 2015

Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-α.

scientific article published on 22 September 2016

Activation of CD36 inhibits and induces regression of inflammatory corneal neovascularization.

scientific article

Adaptive optics imaging of geographic atrophy

scientific article

Adaptive optics ophthalmoscopy: Application to age-related macular degeneration and vascular diseases

scientific article published on 17 July 2018

Age-related macular degeneration: therapeutic hopes

scientific article published on 01 February 2007

Altered astrocyte morphology and vascular development in dystrophin-Dp71-null mice.

scientific article published on 29 December 2015

Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells

scientific article

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

scientific article

Association of Choroidal Interleukin-17-Producing T Lymphocytes and Macrophages with Geographic Atrophy.

scientific article published on 10 June 2016

CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration

scientific article published on 02 December 2010

CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

scientific article published on 21 October 2013

CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-β-induced apoptosis

scientific article published on 08 January 2011

CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice

scientific article published on 01 January 2019

CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents

scientific article (publication date: February 2008)

CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits.

scientific article published on December 2010

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

scientific article

Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction.

scientific article published on 08 December 2016

Choroidal involution is a key component of oxygen-induced retinopathy

scientific article published on 05 August 2011

Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation.

scientific article published on 16 March 2018

Col4a1 mutation generates vascular abnormalities correlated with neuronal damage in a mouse model of HANAC syndrome

scientific article published on 2 January 2017

Comment on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration" by Luhmann et al. (Exp. Eye Res. 2013; 107: 80.doi: 10.1016).

scientific article published on 10 February 2013

Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation.

scientific article published on February 2017

Complement factor H and related proteins in age-related macular degeneration

scientific article published on 25 February 2014

Comprehensive analysis of mouse retinal mononuclear phagocytes.

scientific article published on 4 May 2017

Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation

scientific article

Cyclooxygenase-2 in human and experimental ischemic proliferative retinopathy

scientific article

Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions.

scientific article published on June 2013

Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

scientific article published on 19 June 2020

Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages

scientific article

Development of a novel noncompetitive antagonist of IL-1 receptor

scientific article published on 01 May 2008

Dominant role for calpain in thromboxane-induced neuromicrovascular endothelial cytotoxicity

scientific article

Dystrophin Dp71 gene deletion induces retinal vascular inflammation and capillary degeneration

scientific article

ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.

scientific article published on 15 March 2016

Effects of triamcinolone acetonide on vessels of the posterior segment of the eye.

scientific article

Epidemiology and pathophysiology of retinopathy of prematurity

scientific article

Erratum to: Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.

scientific article published on 19 December 2012

Evidence of the involvement of dystrophin Dp71 in corneal angiogenesis

scientific article published on 14 November 2019

Experimental Branch Retinal Vein Occlusion Induces Upstream Pericyte Loss and Vascular Destabilization

scientific article published on 24 July 2015

Further insights into GPR179: expression, localization, and associated pathogenic mechanisms leading to complete congenital stationary night blindness

scientific article

Genetic ablation of CD36 induces age-related corneal neovascularization

scientific article published on 01 October 2008

Gut microbiota influences pathological angiogenesis in obesity-driven choroidal neovascularization

scientific article

Hypercapnia prevents neovascularization via nitrative stress

scientific article published on 14 November 2005

Hypercapnia- and trans-arachidonic acid-induced retinal microvascular degeneration: implications in the genesis of retinopathy of prematurity

scientific article published on June 2006

Hypercapnia- and trans-arachidonic acid-induced retinal microvascular degeneration: implications in the genesis of retinopathy of prematurity

scientific article published in November 2007

Hyperoxic exposure leads to nitrative stress and ensuing microvascular degeneration and diminished brain mass and function in the immature subject.

scientific article published on 28 September 2006

IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis

scientific article published on 03 January 2020

Immunometabolic modulation of retinal inflammation by CD36 ligand

scientific article published on 09 September 2019

Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis

scientific article published on 12 June 2020

Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity

scientific article published in April 2003

Inducible nitric oxide synthase mediates retinal apoptosis in ischemic proliferative retinopathy.

scientific article

Inducible nitric oxide synthase mediates the change from retinal to vitreal neovascularization in ischemic retinopathy

scientific article

Inflammatory lipid mediators in ischemic retinopathy

scientific article

Insulin inhibits inflammation-induced cone death in retinal detachment

scientific article published on 26 November 2020

Interleukin-1 and ischemic brain injury in the newborn: development of a small molecule inhibitor of IL-1 receptor

scientific article

Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.

scientific article published on May 2011

Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma.

scientific article

Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration? ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Isomer-specific contractile effects of a series of synthetic f2-isoprostanes on retinal and cerebral microvasculature.

scientific article published in January 2004

Lebecetin, a C-type lectin, inhibits choroidal and retinal neovascularization.

scientific article published on 14 December 2016

Light-induced modifications of the outer retinal hyperreflective layers on spectral-domain optical coherence tomography in humans: an experimental study

scientific article published on 04 January 2021

Lipid-bloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice

scientific article published on 18 April 2008

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.

scientific article

Microglia and interleukin-1β in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A.

scientific article published on 13 June 2013

Microglia versus Monocytes: Distinct Roles in Degenerative Diseases of the Retina

scientific article published on 17 April 2020

Microglia/macrophages migrate through retinal epithelium barrier by a transcellular route in diabetic retinopathy: role of PKCζ in the Goto Kakizaki rat model

scientific article

Microvascular rarefaction and decreased angiogenesis in rats with fetal programming of hypertension associated with exposure to a low-protein diet in utero.

scientific article published on 21 July 2005

Mo-derived perivascular macrophage recruitment protects against endothelial cell death in retinal vein occlusion

scientific article published on 27 July 2019

Modifications to the classical rat aortic ring model to allow vascular degeneration studies

scientific article published on 21 January 2021

Modulation of pro-inflammatory gene expression by nuclear lysophosphatidic acid receptor type-1.

scientific article published on 7 July 2003

Neonatal hyperglycemia inhibits angiogenesis and induces inflammation and neuronal degeneration in the retina

scientific article

Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.

scientific article

Neural and angiogenic defects in eyes of transgenic mice expressing a dominant-negative FGF receptor in the pigmented cells

scientific article published in October 2000

Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome.

scientific article

Neuropilin-1-Expressing Microglia Are Associated With Nascent Retinal Vasculature Yet Dispensable for Developmental Angiogenesis

scientific article published on April 2016

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

scientific article published on 01 August 2020

New insights into the retinal circulation: inflammatory lipid mediators in ischemic retinopathy

scientific article

Nitric oxide synthase-II is expressed in severe corneal alkali burns and inhibits neovascularization

scientific article published in November 1999

On phagocytes and macular degeneration

scientific article published on 7 June 2017

Polymorphism in the microglial cell-mobilizing CX3CR1 gene is associated with survival in patients with glioblastoma.

scientific article

Potential role of microglia in retinal blood vessel formation

scientific article published in August 2006

Prevalence and risk factors for outer retinal layer damage after macula-off retinal detachment

scientific article published on 28 August 2019

Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent

scientific journal article

Protease nexin-1 regulates retinal vascular development

article

Protection of Glial Müller Cells by Dexamethasone in a Mouse Model of Surgically Induced Blood-Retinal Barrier Breakdown.

scientific article published on February 2017

Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina.

scientific article published on 31 July 2011

Redox-dependent effects of nitric oxide on microvascular integrity in oxygen-induced retinopathy.

scientific article published in December 2004

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life

scientific article

Review and expert opinion in age related macular degeneration. Focus on the pathophysiology, angiogenesis and pharmacological and clinical data

scientific article

Role of chemokines in the development of age-related macular degeneration

scientific article published on January 2010

Role of the chemokine receptor CX3CR1 in the mobilization of phagocytic retinal microglial cells

scientific article published on 27 May 2008

Single-stranded oligonucleotide-mediated in vivo gene repair in the rd1 retina.

scientific article published on 2 May 2007

Spectral-domain optical coherence tomography of the rodent eye: highlighting layers of the outer retina using signal averaging and comparison with histology

scientific article

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β.

scientific article published on 20 July 2016

The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination

scientific article published on 01 August 2020

The 3D Retinal Capillary Circulation in Pigs Reveals a Predominant Serial Organization.

scientific article published in November 2017

The Oxygen Paradox, the French Paradox, and age-related diseases.

scientific article

The familial dementia gene revisited: a missense mutation revealed by whole-exome sequencing identifies ITM2B as a candidate gene underlying a novel autosomal dominant retinal dystrophy in a large family.

scientific article

The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

scientific article published on 5 October 2008

Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice.

scientific article published on 2 September 2015

Thrombospondin-1 and Pathogenesis of Age-Related Macular Degeneration

scientific article published on 18 May 2015

Tissue factor enhances protease-activated receptor-2-mediated factor VIIa cell proliferative properties

scientific article

Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration

scientific article published on 27 November 2005

Understanding ischemic retinopathies: emerging concepts from oxygen-induced retinopathy.

scientific article published on 31 October 2009

Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration.

scientific article published on May 2015

VEGFR-1: a safe target for prophylaxis of retinopathy of prematurity?

scientific article published on 19 November 2003

Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness

scientific article

[Macular degeneration: retinal microglial cells are guilty]

scientific article published on 01 April 2008

[On the inflammatory origins of AMD]

scientific article published on 07 October 2020

[Pathophysiology of retinopathy of prematurity]

scientific article published on 11 May 2006

[Polymorphisms of complement factor genes and age-related macular degeneration in a German population]

scientific article published on 27 April 2009

trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature.

scientific article

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