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List of works by Chris M Grant

A quantitative and temporal map of proteostasis during heat shock in Saccharomyces cerevisiae

scientific article published on 16 January 2018

A single glutaredoxin or thioredoxin gene is essential for viability in the yeast Saccharomyces cerevisiae

scientific article published on 01 June 2000

A single inhibitory upstream open reading frame (uORF) is sufficient to regulate Candida albicans GCN4 translation in response to amino acid starvation conditions

scientific article published on 25 February 2014

Absolute protein quantification of the yeast chaperome under conditions of heat shock

scientific article published on 2 June 2016

Antioxidant activity of the yeast mitochondrial one-Cys peroxiredoxin is dependent on thioredoxin reductase and glutathione in vivo.

scientific article

Archetypal transcriptional blocks underpin yeast gene regulation in response to changes in growth conditions.

scientific article

Arsenite interferes with protein folding and triggers formation of protein aggregates in yeast

scientific article published on 03 September 2012

Autophagy protects against de novo formation of the [PSI+] prion in yeast

scientific article published on 21 October 2015

Butanol production in S. cerevisiae via a synthetic ABE pathway is enhanced by specific metabolic engineering and butanol resistance

scientific article

Candida albicans and three other Candida species contain an elongation factor structurally and functionally analogous to elongation factor 3

scientific article published in May 1991

Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors

scientific article published on 26 September 2003

Cytosolic thioredoxin system facilitates the import of mitochondrial small Tim proteins

scientific article published on 10 August 2012

Differential protein S-thiolation of glyceraldehyde-3-phosphate dehydrogenase isoenzymes influences sensitivity to oxidative stress

scientific article

Differential regulation of glutaredoxin gene expression in response to stress conditions in the yeast Saccharomyces cerevisiae

scientific article published on 01 January 2000

Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction Monitoring.

scientific article published on 10 January 2016

Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI+] prion formation.

scientific article

Distinct stress conditions result in aggregation of proteins with similar properties

scientific article

Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses

scientific article published on 27 October 2017

ER stress causes widespread protein aggregation and prion formation.

scientific article published on 19 June 2017

Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control

scientific article published on January 1994

Electrophoretic analysis of yeast proteins

scientific article published on January 1996

Endoplasmic reticulum (ER) stress-induced reactive oxygen species (ROS) are detrimental for the fitness of a thioredoxin reductase mutant

scientific article published on 05 June 2018

Errors in stop codon recognition in a temperature sensitive mutation of yeast

scientific article published on 01 November 1993

Gcn4 is required for the response to peroxide stress in the yeast Saccharomyces cerevisiae.

scientific article published on 16 April 2008

Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae

scientific article published on 27 October 2004

Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy.

scientific article published on 28 June 2011

Global analysis of protein aggregation in yeast during physiological conditions and arsenite stress.

scientific article

Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways

scientific article published on November 2005

Global mRNA selection mechanisms for translation initiation.

scientific article

Global translational responses to oxidative stress impact upon multiple levels of protein synthesis.

scientific article published on 18 July 2006

Glutathione and catalase provide overlapping defenses for protection against hydrogen peroxide in the yeast Saccharomyces cerevisiae.

scientific article

Glutathione is an essential metabolite required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae

scientific article published in May 1996

Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine

scientific article

Identification of a Saccharomyces cerevisiae mitochondrial-DNA which can act as a promoter tightly regulated by carbon source when placed in the nucleus

scientific article published on 01 February 1997

Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins

scientific article

Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

scientific article

Integrated multi-omics reveals common properties underlying stress granule and P-body formation

scientific article published on 21 October 2021

Involvement of the Saccharomyces cerevisiae UTH1 gene in the oxidative-stress response.

scientific article

Loss of mRNA surveillance pathways results in widespread protein aggregation

scientific article published in March 2018

Metabolic reconfiguration is a regulated response to oxidative stress.

scientific article published on January 2008

Methionine oxidation of Sup35 protein induces formation of the [PSI+] prion in a yeast peroxiredoxin mutant.

scientific article

Mistranslation induces the heat-shock response in the yeast Saccharomyces cerevisiae

scientific article published on 01 February 1989

Mistranslation of human phosphoglycerate kinase in yeast in the presence of paromomycin

scientific article published on 01 August 1994

Mitochondrial function is required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae

scientific article published on 01 June 1997

Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems

scientific article published on February 2003

Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae

scientific article published on July 2006

Overlapping roles of the cytoplasmic and mitochondrial redox regulatory systems in the yeast Saccharomyces cerevisiae

scientific article published on February 2005

Oxidant-specific regulation of protein synthesis in Candida albicans

scientific article published in April 2014

Oxidation of the yeast mitochondrial thioredoxin promotes cell death

scientific article published on 27 August 2012

Oxidative damage to proteins in yeast cells exposed to adaptive levels of H(2)O(2).

scientific article published in January 2003

Oxidative stress conditions increase the frequency of de novo formation of the yeast [PSI+] prion

scientific article

Protein S-thiolation targets glycolysis and protein synthesis in response to oxidative stress in the yeast Saccharomyces cerevisiae

scientific article

Puf3p induces translational repression of genes linked to oxidative stress

scientific article published on 25 October 2013

Quantitative analysis of chaperone network throughput in budding yeast.

scientific article published on 15 March 2013

Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in Saccharomyces cerevisiae

scientific article published on 16 February 2015

Redox Control of Exofacial Protein Thiols/Disulfides by Protein Disulfide Isomerase

scientific article published in Journal of Biological Chemistry

Regulation of Translation by Hydrogen Peroxide ⬇️

scientific article published on April 10, 2011

Regulation of protein S-thiolation by glutaredoxin 5 in the yeast Saccharomyces cerevisiae

scientific article published on 6 March 2002

Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions.

scientific article

Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides

scientific article

Rom2p, the Rho1 GTP/GDP exchange factor of Saccharomyces cerevisiae, can mediate stress responses via the Ras-cAMP pathway.

scientific article

Saccharomyces cerevisiae exhibits a yAP-1-mediated adaptive response to malondialdehyde

scientific article

Sequences 5' of the first upstream open reading frame in GCN4 mRNA are required for efficient translational reinitiation.

scientific article

Spermidine cures yeast of prions

scientific article published on 25 December 2015

Stationary-phase induction of GLR1 expression is mediated by the yAP-1 transcriptional regulatory protein in the yeast Saccharomyces cerevisiae.

scientific article

Stationary-phase regulation of the Saccharomyces cerevisiae SOD2 gene is dependent on additive effects of HAP2/3/4/5- and STRE-binding elements

scientific article

Sup35 methionine oxidation is a trigger for de novo [PSI(+)] prion formation

scientific article (publication date: 2015)

Synthesis and role of glutathione in protection against oxidative stress in yeast

scientific article

The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation

scientific article published on 14 May 2015

The adaptive response of anaerobically grown Saccharomyces cerevisiae to hydrogen peroxide is mediated by the Yap1 and Skn7 transcription factors

scientific article published on 15 September 2008

The allosuppressor gene SAL4 encodes a protein important for maintaining translational fidelity in Saccharomyces cerevisiae

scientific article published on 01 December 1988

The critical role of glutathione in maintenance of the mitochondrial genome

scientific article published on 29 September 2010

The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing

scientific article published on 01 September 1998

The essential and ancillary role of glutathione in Saccharomyces cerevisiae analysed using a grande gsh1 disruptant strain

scientific article published in April 2001

The freeze-thaw stress response of the yeast Saccharomyces cerevisiae is growth phase specific and is controlled by nutritional state via the RAS-cyclic AMP signal transduction pathway

scientific article

The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses.

scientific article

The non-stop decay mRNA surveillance pathway is required for oxidative stress tolerance

scientific article published on 2 May 2017

The response to heat shock and oxidative stress in Saccharomyces cerevisiae

scientific article published on 29 December 2011

The thioredoxin system protects ribosomes against stress-induced aggregation

scientific article

The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae

scientific article published on December 2009

The use of allosuppressor alleles of the SAL4 gene in the study of translational fidelity in Saccharomyces cerevisiae

scientific article published on 01 August 1991

The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response.

scientific article

The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species.

scientific article

The yeast peroxiredoxin Tsa1 protects against protein-aggregate-induced oxidative stress

scientific article

Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae

scientific article published in November 2002

Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae.

scientific article

Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: involvement of a respiration-related process for maximal sensitivity and adaptive response

scientific article published on February 1998

Unconventional Targeting of a Thiol Peroxidase to the Mitochondrial Intermembrane Space Facilitates Oxidative Protein Folding.

scientific article

Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast.

scientific article

Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for yAP-1 transcriptional regulation

scientific article published on 01 July 1996

Yeast mitochondrial glutathione is an essential antioxidant with mitochondrial thioredoxin providing a back-up system

scientific article

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