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List of works by Nick C. Fox

11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

scientific article published on 26 February 2010

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

scientific article published in February 2018

3D characterization of brain atrophy in Alzheimer's disease and mild cognitive impairment using tensor-based morphometry

scientific article published on 21 February 2008

A Comparison of Accelerated and Non-accelerated MRI Scans for Brain Volume and Boundary Shift Integral Measures of Volume Change: Evidence from the ADNI Dataset.

scientific article

A Novel MAPT Mutation Causing Corticobasal Syndrome Led by Progressive Apraxia of Speech

scientific article published on 16 September 2015

A cognitive chameleon: lessons from a novel MAPT mutation case.

scientific article

A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies

scientific article

A comparison of methods for the automated calculation of volumes and atrophy rates in the hippocampus.

scientific article

A comparison of voxel and surface based cortical thickness estimation methods

scientific article

A data-driven model of biomarker changes in sporadic Alzheimer's disease

scientific article

A decade of pre-diagnostic assessment in a case of familial Alzheimer's disease: tracking progression from asymptomatic to MCI and dementia.

scientific article published in February 2005

A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series

scientific article published on 29 January 2008

A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging

scientific article

A meta-analysis of hippocampal atrophy rates in Alzheimer's disease

scientific article published on 17 March 2008

A novel A781V mutation in the CSF1R gene causes hereditary diffuse leucoencephalopathy with axonal spheroids

scientific article published on 28 June 2013

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

A novel use of arterial spin labelling MRI to demonstrate focal hypoperfusion in individuals with posterior cortical atrophy: a multimodal imaging study

scientific article published on 5 January 2016

A peek behind the curtain: amyloid imaging, referrals, and specialist memory evaluations

scientific article published in January 2013

A population-based study of head injury, cognitive function and pathological markers

scientific article

A practical approach to diagnosing adult onset leukodystrophies

scientific article published on 19 December 2013

A presenilin 1 R278I mutation presenting with language impairment.

scientific article published in November 2004

A second family with familial AD and the V717L APP mutation has a later age at onset.

scientific article published in February 2006

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease

scientific article published on 11 March 2020

A systematic review and meta-analysis of CSF neurofilament protein levels as biomarkers in dementia.

scientific article published on January 2007

A volumetric magnetic resonance imaging study of the amygdala in frontotemporal lobar degeneration and Alzheimer's disease

scientific article published on 05 August 2005

A volumetric study of hippocampus and amygdala in depressed patients with subjective memory problems

scientific article published in January 2000

A voxel-based morphometry study of volumetric MRI in familial Alzheimer's disease

Accelerated vs. unaccelerated serial MRI based TBM-SyN measurements for clinical trials in Alzheimer's disease

scientific article published on 20 March 2015

Accelerating regional atrophy rates in the progression from normal aging to Alzheimer's disease

scientific article published on 18 July 2009

Acceleration of cortical thinning in familial Alzheimer's disease.

scientific article published on 14 December 2009

Acceleration of hippocampal atrophy rates in asymptomatic amyloidosis

scientific article published on 22 October 2015

Accuracy assessment of global and local atrophy measurement techniques with realistic simulated longitudinal Alzheimer's disease images

scientific article

Accuracy of dementia diagnosis: a direct comparison between radiologists and a computerized method

scientific article (publication date: November 2008)

Accurate automatic estimation of total intracranial volume: a nuisance variable with less nuisance

scientific article

Accurate registration of serial 3D MR brain images and its application to visualizing change in neurodegenerative disorders

scientific article

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

scientific article

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

scientific article published on 03 December 2019

Algorithms, atrophy and Alzheimer's disease: Cautionary tales for clinical trials

scientific article published on February 4, 2011

Alzheimer's disease due to an intronic presenilin-1 (PSEN1 intron 4) mutation: A clinicopathological study.

scientific article published in May 2000

Alzheimer's disease in the 100 years since Alzheimer's death

scientific article published on 4 November 2015

Amnestic mild cognitive impairment: structural MR imaging findings predictive of conversion to Alzheimer disease.

scientific article published on 22 February 2008

Amyloid load and cerebral atrophy in Alzheimer's disease: an 11C-PIB positron emission tomography study

scientific article published in July 2006

Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study

scientific article published on 25 October 2006

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

scientific article

Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

scientific article

An algorithmic approach to structural imaging in dementia

scientific article

An alternative method for estimating efficacy of the AN1792 vaccine for Alzheimer disease.

scientific article published in August 2008

An automated algorithm for the computation of brain volume change from sequential MRIs using an iterative principal component analysis and its evaluation for the assessment of whole-brain atrophy rates in patients with probable Alzheimer's disease

scientific article published on May 2004

An event-based model for disease progression and its application in familial Alzheimer's disease and Huntington's disease

scientific article

An unbiased longitudinal analysis framework for tracking white matter changes using diffusion tensor imaging with application to Alzheimer's disease

scientific article published on 28 January 2013

An unbiased, staged, multicentre, validation strategy for Alzheimer's disease CSF tau levels.

scientific article published on 11 December 2009

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Apolipoprotein e genotype modifies the phenotype of Alzheimer disease

scientific article published in January 2006

Application of automated medial temporal lobe atrophy scale to Alzheimer disease

scientific article

Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent?

article

Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge

scientific article published on 11 August 2015

Assessing the onset of structural change in familial Alzheimer's disease

scientific article published in February 2003

Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease

scientific article published on 02 December 2019

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

scientific article published on 16 February 2012

Atrophy of the hippocampal formation in early familial Alzheimer's disease. A longitudinal MRI study of at-risk members of a family with an amyloid precursor protein 717Val-Gly mutation

scientific article published in January 1996

Atrophy patterns in Alzheimer's disease and semantic dementia: a comparison of FreeSurfer and manual volumetric measurements.

scientific article published on 27 October 2009

Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials

scientific article

Atrophy rates of the cingulate gyrus and hippocampus in AD and FTLD.

scientific article published on 6 January 2006

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automated brain extraction using Multi-Atlas Propagation and Segmentation (MAPS)

Automated cross-sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease

scientific article

Automated hippocampal segmentation by regional fluid registration of serial MRI: validation and application in Alzheimer's disease

scientific article published in May 2001

Automated measurement of hippocampal atrophy using fluid-registered serial MRI in AD and controls.

scientific article published in July 2007

Automated quantification of caudate atrophy by local registration of serial MRI: evaluation and application in Huntington's disease.

scientific article published on 10 June 2009

Automated template-based hippocampal segmentations from MRI: the effects of 1.5T or 3T field strength on accuracy

scientific article

Automatic calculation of hippocampal atrophy rates using a hippocampal template and the boundary shift integral

scientific article published on 28 August 2006

Automatic classification of MR scans in Alzheimer's disease

scientific article published on 17 January 2008

Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias

scientific article published on September 2002

Autopsy-confirmed familial early-onset Alzheimer disease caused by the l153V presenilin 1 mutation

scientific article published in June 2001

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

scientific article

BRain health and healthy AgeINg in retired rugby union players, the BRAIN Study: study protocol for an observational study in the UK.

scientific article published on 26 December 2017

Baseline CSF p-tau levels independently predict progression of hippocampal atrophy in Alzheimer disease

scientific article

Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment

scientific article published on October 2007

Basic Visual Function and Cortical Thickness Patterns in Posterior Cortical Atrophy

scientific article published on 10 February 2011

Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis

scientific article

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data

scientific article

Biomarkers for Alzheimer's disease therapeutic trials

scientific article published on 02 December 2010

Brain MAPS: an automated, accurate and robust brain extraction technique using a template library

scientific article

Brain amyloid-beta fragment signatures in pathological ageing and Alzheimer's disease by hybrid immunoprecipitation mass spectrometry

scientific article published on 13 January 2015

Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study

Brain atrophy progression measured from registered serial MRI: validation and application to Alzheimer's disease

scientific article

Brain biopsy in dementia.

scientific article

Brain imaging in Alzheimer disease

scientific article

Brain-water diffusion coefficients reflect the severity of inherited prion disease.

scientific article

CANDID--Counselling and Diagnosis in Dementia: a national telemedicine service supporting the care of younger patients with dementia

scientific article published on June 1998

CHCHD10 Pro34Ser is not a highly penetrant pathogenic variant for amyotrophic lateral sclerosis and frontotemporal dementia

scientific article published on 11 September 2015

CSF neurogranin or tau distinguish typical and atypical Alzheimer disease

scientific article published on 11 January 2018

CSF synaptic protein concentrations are raised in those with atypical Alzheimer's disease but not frontotemporal dementia

scientific article published on 17 December 2019

Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes? Relation of the FAB to formal neuropsychological testing

scientific article published on August 2005

Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers

scientific article published on 16 November 2010

Cerebral and cerebellar atrophy on serial magnetic resonance imaging in an initially symptom free subject at risk of familial prion disease

scientific article published on October 4, 1997

Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration

scientific article published on 9 January 2013

Cerebral atrophy measurement in clinically isolated syndromes and relapsing remitting multiple sclerosis: a comparison of registration-based methods

scientific article

Cerebral atrophy measurements using Jacobian integration: comparison with the boundary shift integral

scientific article published on 3 May 2006

Cerebral microbleeds in familial Alzheimer's disease

scientific article published on 17 June 2011

Cerebrospinal fluid S100B correlates with brain atrophy in Alzheimer's disease

scientific article published in January 2003

Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic.

scientific article published on 20 March 2018

Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study

scientific article

Chromosome 14 familial Alzheimer's disease: the clinical and neuropathological characteristics of a family with a leucineright-arrowserine (L250S) substitution at codon 250 of the presenilin 1 gene

scientific article published on January 1, 1998

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

scientific article

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

scientific article

Clinical application of measurement of hippocampal atrophy in degenerative dementias

scientific article

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

scientific article

Clinical features of sporadic and familial Alzheimer's disease

scientific article published on December 1996

Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

scientific article

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease

scientific article published on 01 May 2019

Clinicopathological features of familial Alzheimer's disease associated with the M139V mutation in the presenilin 1 gene. Pedigree but not mutation specific age at onset provides evidence for a further genetic factor

scientific article

Cognition at age 70: Life course predictors and associations with brain pathologies

scientific article published on 30 October 2019

Combining short interval MRI in Alzheimer's disease: Implications for therapeutic trials

scientific article published on 22 September 2006

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

scientific article published on 05 November 2020

Comparison of phantom and registration scaling corrections using the ADNI cohort

scientific article

Computer-assisted imaging to assess brain structure in healthy and diseased brains

scientific article

Consensus classification of posterior cortical atrophy

scientific article published on March 2017

Consistent multi-time-point brain atrophy estimation from the boundary shift integral.

scientific article

Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy

scientific article published on 04 April 2012

Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study.

scientific article

Correction of differential intensity inhomogeneity in longitudinal MR images

scientific article

Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group

scientific article published on 20 September 2016

Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates

scientific article

Cortical thickness and voxel-based morphometry in posterior cortical atrophy and typical Alzheimer's disease

scientific article published on 25 September 2009

Cross-sectional cerebral volumetric differences and associations with estimated time to age-at-onset in familial Alzheimer's disease: Findings from the DIAN study

article

Data-driven models of dominantly-inherited Alzheimer's disease progression

scientific article published on 22 March 2018

Data-driven models of dominantly-inherited Alzheimer's disease progression

scholarly article published 19 January 2018

Defective emotion recognition in early HD is neuropsychologically and anatomically generic.

scientific article published on 6 March 2008

Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI.

scientific article published in August 2003

Delusions in frontotemporal lobar degeneration

scientific article published on 09 April 2009

Dementia prevention, intervention, and care.

scientific article

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

scientific article published on 29 July 2020

Dementia: Clinical Background

scholarly article published 20 October 2010

Dementias with Associated ‘Brain Swelling’

Description of a simple test for CADASIL disease and determination of mutation frequencies in sporadic ischaemic stroke and dementia patients

scientific article published on November 2000

Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force

scientific article published in July 2013

Detecting treatment effects on brain atrophy in relapsing remitting multiple sclerosis: sample size estimates

scientific article published on 25 October 2007

Development of selective verbal memory impairment secondary to a left thalamic infarct: a longitudinal case study.

scientific article

Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT

scientific article

Differential hippocampal shapes in posterior cortical atrophy patients: A comparison with control and typical AD subjects

scientific article published on 13 October 2015

Differential regional atrophy of the cingulate gyrus in Alzheimer disease: a volumetric MRI study.

scientific article published on 4 January 2006

Differentiating AD from aging using semiautomated measurement of hippocampal atrophy rates

scientific article published in October 2004

Diffusion imaging changes in grey matter in Alzheimer's disease: a potential marker of early neurodegeneration

scientific article published on July 2015

Disorders Mainly Affecting White Matter

Dissecting IWG-2 typical and atypical Alzheimer's disease: insights from cerebrospinal fluid analysis

scientific article published on 26 September 2015

Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation.

scientific article published on 17 August 2011

Distinct profiles of brain atrophy in frontotemporal lobar degeneration caused by progranulin and tau mutations

scientific article

Do symptoms of memory impairment correspond to cognitive impairment: a cross sectional study of a clinical cohort.

scientific article published on December 2006

Does Alzheimer's disease affect hippocampal asymmetry? Evidence from a cross-sectional and longitudinal volumetric MRI study

scientific article published on 22 March 2005

Does registration of serial MRI improve diagnosis of dementia?

scientific article published on 27 February 2010

EFNS task force: the use of neuroimaging in the diagnosis of dementia.

scientific article published on 20 August 2012

Early onset familial Alzheimer's disease: Mutation frequency in 31 families.

scientific article

Early-onset Alzheimer disease clinical variants: multivariate analyses of cortical thickness

scientific article

Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE ɛ4 allele

scientific article published on December 22, 2010

Effect of Spinal Manometers on Cerebrospinal Fluid Amyloid-β Concentration

scientific article published on 01 January 2017

Effect of age at onset on cortical thickness and cognition in posterior cortical atrophy

scientific article published on 25 April 2016

Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study

scientific article

Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.

scientific article published in May 2005

Effects of changing from non-accelerated to accelerated MRI for follow-up in brain atrophy measurement

scientific article

Erratum to: Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay

scientific article published on 23 February 2016

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

article

Exome sequencing reveals a novel partial deletion in the progranulin gene causing primary progressive aphasia

scientific article published on 31 July 2013

Familial Alzheimer's disease and inherited prion disease in the UK are poorly ascertained

scientific article published on 27 August 2010

Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta

scientific article published on 12 April 2019

Fast free-form deformation using graphics processing units

scientific article published on 8 October 2009

Frontotemporal dementia and its subtypes: a genome-wide association study

scientific article

Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features

scientific article

Functional connectivity in autosomal dominant and late-onset Alzheimer disease

scientific article

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic analysis of inherited leukodystrophies: genotype-phenotype correlations in the CSF1R gene

scientific article

Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease.

scientific article published on 4 September 2015

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genetic influences on atrophy patterns in familial Alzheimer's disease: a comparison of APP and PSEN1 mutations

scientific article published on January 2013

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

scientific article published on 15 March 2016

Genetic variability in CLU and its association with Alzheimer's disease

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease.

scientific article published in October 2004

Global gray matter changes in posterior cortical atrophy: a serial imaging study

scientific article

Gray matter atrophy rate as a marker of disease progression in AD.

scientific article published on 15 December 2010

HECTD2, a candidate susceptibility gene for Alzheimer's disease on 10q.

scientific article published on 15 September 2009

Haemodialysis and Cerebral Oedema

scientific article published on 01 February 2001

Head size, age and gender adjustment in MRI studies: a necessary nuisance?

scientific article published on 16 June 2010

Hippocampal atrophy rates in Alzheimer disease: added value over whole brain volume measures.

scientific article

How to Use This Book?

Identification of an important potential confound in CSF AD studies: aliquot volume

scientific article published in December 2013

Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay

scientific article published in December 2015

Imaging biomarkers in Alzheimer's disease.

scientific article published in October 2009

Imaging cadavers: cold FLAIR and noninvasive brain thermometry using CSF diffusion

scientific article

Imaging cerebral atrophy: normal ageing to Alzheimer's disease

scientific article published on January 2004

Imaging markers for Alzheimer disease: which vs how

scientific article

Imaging of onset and progression of Alzheimer's disease with voxel-compression mapping of serial magnetic resonance images.

scientific article published in July 2001

Imaging the onset and progression of Alzheimer's disease: implications for prevention trials

scientific article

Impact of apolipoprotein E4-cerebrospinal fluid β-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment

scientific article

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

scientific article published on 24 July 2013

Improved reliability of hippocampal atrophy rate measurement in mild cognitive impairment using fluid registration

scientific article published on 15 December 2006

Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation

scientific article published in The Lancet

Increased CSF neurogranin concentration is specific to Alzheimer disease

scientific article published on 29 January 2016

Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42.

scientific article published in December 2010

Increased hippocampal atrophy rates in AD over 6 months using serial MR imaging.

scientific article published on 26 March 2007

Increased rate of whole-brain atrophy over 6 months in early Huntington disease.

scientific article published in August 2006

Increased variability in reaction time is associated with amyloid beta pathology at age 70

scientific article published on 10 August 2020

Inflammatory changes in very early Alzheimer's disease: friend, foe, or don't know?

scientific article

Intensity non-uniformity correction using N3 on 3-T scanners with multichannel phased array coils

scientific article published on 30 October 2007

Interactive algorithms for the segmentation and quantitation of 3-D MRI brain scans.

scientific article published in May 1997

Intracranial Volume and Alzheimer Disease

scientific article published on 01 February 2000

Investigating the relationship between BMI across adulthood and late life brain pathologies

scientific article

Issues with threshold masking in voxel-based morphometry of atrophied brains

scientific article

Knight's move thinking? Mild cognitive impairment in a chess player.

scientific article published in February 2005

Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population.

scientific article published on 21 February 2013

LoAd: a locally adaptive cortical segmentation algorithm

scientific article published on 23 February 2011

Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders

scientific article

Long-term retrograde amnesia...the crucial role of the hippocampus

scientific article published on January 2001

Longitudinal MRI in progressive supranuclear palsy and multiple system atrophy: rates and regions of atrophy

scientific article published on 2 February 2006

Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: cross-validation of BSI, SIENA and SIENAX.

scientific article

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

scientific article published on 14 September 2018

Longitudinal diffusion tensor imaging in frontotemporal dementia.

scientific article

Longitudinal imaging in dementia.

scientific article

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease

scholarly article by Philip S J Weston et al published 20 February 2019 in Alzheimers Research & Therapy

Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions.

scientific article

Longitudinal patterns of regional change on volumetric MRI in frontotemporal lobar degeneration

scientific article published on January 2004

Longitudinal stability of MRI for mapping brain change using tensor-based morphometry

scientific article published on 15 February 2006

MIRIAD--Public release of a multiple time point Alzheimer's MR imaging dataset

scientific article published on 28 December 2012

MR image texture analysis applied to the diagnosis and tracking of Alzheimer's disease

scientific article published in June 1998

MRI derived brain atrophy in PSP and MSA-P. Determining sample size to detect treatment effects

scientific article

MRI visual rating scales in the diagnosis of dementia: evaluation in 184 post-mortem confirmed cases

scientific article published on March 2016

MRS shows abnormalities before symptoms in familial Alzheimer disease

scientific article published in March 2006

Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease

scientific article published on 28 March 2013

Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2

scientific article

Magnetic resonance imaging measures of brain atrophy in multiple sclerosis

scientific article

Magnetic resonance imaging predictors of cognition in mild cognitive impairment

scientific article

Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia

scientific article

Mapping the evolution of regional atrophy in Alzheimer's disease: unbiased analysis of fluid-registered serial MRI.

scientific article

Mapping the onset and progression of atrophy in familial frontotemporal lobar degeneration.

scientific article

Mapping the progression of progranulin-associated frontotemporal lobar degeneration

scientific article

Measurements of the amygdala and hippocampus in pathologically confirmed Alzheimer disease and frontotemporal lobar degeneration

scientific article published on October 2006

Measuring atrophy in Alzheimer disease: a serial MRI study over 6 and 12 months

scientific article published in July 2005

Measuring brain atrophy with a generalized formulation of the boundary shift integral

scientific article

Measuring disease progression in frontotemporal lobar degeneration: a clinical and MRI study.

scientific article

Memantine and brain atrophy in Alzheimer's disease: a 1-year randomized controlled trial

scientific article published in January 2012

Memory complaints and increased rates of brain atrophy: risk factors for mild cognitive impairment and Alzheimer's disease.

scientific article

Mere forgetfulness or early Alzheimer's disease?

scientific article published in April 2000

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

scientific article

Microglial activation and amyloid deposition in mild cognitive impairment: a PET study

scientific article

Modeling brain deformations in Alzheimer disease by fluid registration of serial 3D MR images

scientific article published in September 1998

Molecular nexopathies: a new paradigm of neurodegenerative disease

scientific article published on 19 July 2013

Motor features in posterior cortical atrophy and their imaging correlates

scientific article

NeuroGrid: Using Grid Technology to Advance Neuroscience

Neurofilament inclusion body disease: a new proteinopathy?

scientific article published on 22 July 2003

Neuroimaging in Dementia

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

scientific article

Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).

scientific article

Neuronal intranuclear inclusion disease is genetically heterogeneous

scientific article published on 10 August 2020

Neuropsychological correlates of whole brain atrophy in Alzheimer's disease

scientific article published on 10 March 2008

New developments in mild cognitive impairment and Alzheimer's disease

scientific article published on December 2006

No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.

scientific article published on 2 August 2011

Nonlinear Elastic Spline Registration: Evaluation with Longitudinal Huntington’s Disease Data

article

Normal Ageing

Nothing to say, something to sing: primary progressive dynamic aphasia

scientific article

Olfactory testing does not predict β-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort

scientific article published on 24 June 2020

Onset and progression of pathologic atrophy in Huntington disease: a longitudinal MR imaging study

scientific article published on 11 February 2010

Operationalizing hippocampal volume as an enrichment biomarker for amnestic mild cognitive impairment trials: effect of algorithm, test-retest variability, and cut point on trial cost, duration, and sample size

scientific article

Optimizing the design of clinical trials where the outcome is a rate. Can estimating a baseline rate in a run-in period increase efficiency?

scientific article published on August 2008

P2-158 Effect of galantamine treatment on brain atrophy as assessed by MRI in patients with mild cognitive impairment

Parietal lobe deficits in frontotemporal lobar degeneration caused by a mutation in the progranulin gene

scientific article published on April 2008

Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels

scientific article

Pathological substrate for regional distribution of increased atrophy rates in progressive supranuclear palsy.

scientific article

Patterns of atrophy in pathologically confirmed dementias: a voxelwise analysis

scientific article

Patterns of cortical thickness according to APOE genotype in Alzheimer's disease

scientific article published on 26 November 2009

Patterns of longitudinal brain atrophy in the logopenic variant of primary progressive aphasia

scientific article published on 08 February 2013

Phenomenological model of diffuse global and regional atrophy using finite-element methods

scientific article published in November 2006

Pitfalls in the use of voxel-based morphometry as a biomarker: examples from huntington disease

scientific article published on 24 December 2009

Posterior cerebral atrophy in the absence of medial temporal lobe atrophy in pathologically-confirmed Alzheimer's disease

scientific article published on 18 May 2011

Posterior cortical atrophy

article

Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial.

scientific article

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning

scientific article published on 11 February 2020

Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study.

scientific article published on 21 July 2017

Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis.

scientific article published on 4 February 2015

Presymptomatic cognitive deficits in individuals at risk of familial Alzheimer's disease. A longitudinal prospective study.

scientific article published in September 1998

Presymptomatic generalized brain atrophy in frontotemporal dementia caused by CHMP2B mutation

scientific article published on 7 February 2009

Presymptomatic hippocampal atrophy in Alzheimer's disease. A longitudinal MRI study

scientific article published in December 1996

Presymptomatic studies in genetic frontotemporal dementia.

scientific article published on 04 September 2013

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia

scientific article published on 01 November 2018

Primary Grey Matter Loss

scholarly article published 20 October 2010

Profiles of white matter tract pathology in frontotemporal dementia

scientific article

Pure progressive amnesia and the APPV717G mutation

scientific article published in October 2009

Qualitative changes in human γ-secretase underlie familial Alzheimer's disease

scientific article

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group

scientific article

Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy

scientific article published in February 2005

Quantitative magnetization transfer imaging in Alzheimer disease

scientific article published in September 2007

R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rate and acceleration of whole-brain atrophy in premanifest and early Huntington's disease

scientific article published on May 2010

Rates of hemispheric and lobar atrophy in the language variants of frontotemporal lobar degeneration

scientific article

Reduced cortical thickness in the posterior cingulate gyrus is characteristic of both typical and atypical Alzheimer's disease

scientific article published in January 2010

Regional brain volumes distinguish PSP, MSA-P, and PD: MRI-based clinico-radiological correlations

scientific article published in July 2006

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

scientific article

Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease

scientific article published in February 2009

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease

scientific article published on 25 September 2018

Revising the definition of Alzheimer's disease: a new lexicon.

scientific article published on 9 October 2010

Robust atrophy rate measurement in Alzheimer's disease using multi-site serial MRI: tissue-specific intensity normalization and parameter selection

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SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases

scientific article published on 20 June 2019

STEPS: Similarity and Truth Estimation for Propagated Segmentations and its application to hippocampal segmentation and brain parcelation

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Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest

scientific article published on 13 April 2019

Secondary prevention of Alzheimer's dementia: neuroimaging contributions

scientific article published on 30 October 2018

Seeing what alzheimer saw-with magnetic resonance microscopy

scientific article published in January 2000

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

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Serial magnetic resonance imaging of cerebral atrophy in preclinical Alzheimer's disease

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Serial volumetric MRI in Parkinsonian disorders

scientific article published on January 2009

Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease

scientific article published on 06 June 2020

Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia

scientific article published on 31 August 2016

Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration

scientific article published on 25 October 2017

Shining a light on posterior cortical atrophy

scientific article published on 28 December 2012

Short echo time proton magnetic resonance spectroscopy in Alzheimer's disease: a longitudinal multiple time point study

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Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease

scientific article published on 15 July 2020

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

scientific article published on 31 January 2018

Spontaneous ARIA (amyloid-related imaging abnormalities) and cerebral amyloid angiopathy related inflammation in presenilin 1-associated familial Alzheimer's disease

scientific article published in January 2015

Sporadic and familial dementia with ubiquitin-positive tau-negative inclusions: clinical features of one histopathological abnormality underlying frontotemporal lobar degeneration

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Standardization of analysis sets for reporting results from ADNI MRI data

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Stem cell therapy for Alzheimer's disease: hope or hype?

scientific article published on 15 December 2015

Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease

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Structural imaging markers for therapeutic trials in Alzheimer's disease.

scientific article published in April 2009

Structural magnetic resonance imaging in the practical assessment of dementia: beyond exclusion

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Structural magnetic resonance imaging-derived biomarkers for Alzheimer's disease

scientific article published on June 2007

Structural neuroanatomy of tinnitus and hyperacusis in semantic dementia

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Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis

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TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

scientific article published on 19 January 2014

Targeted recruitment using cerebrospinal fluid biomarkers: implications for Alzheimer's disease therapeutic trials

scientific article published in January 2013

Ten simple rules for reporting voxel-based morphometry studies.

scientific article published on 17 January 2008

The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods

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The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease

scientific article published on 21 March 2019

The G8 Dementia Research Summit--a starter for eight?

scientific article published in December 2013

The Toolbox

2010 article

The analysis of repeated 'direct' measures of change illustrated with an application in longitudinal imaging

scientific article published on November 2004

The application of serial MRI analysis techniques to the study of cerebral atrophy in late-onset dementia

scientific article published on March 2004

The boundary shift integral: an accurate and robust measure of cerebral volume changes from registered repeat MRI.

scientific article published in October 1997

The clinical and neuroanatomical phenotype of FUS associated frontotemporal lobar degeneration

scientific article published on 16 July 2010

The clinical profile of right temporal lobe atrophy

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The clinical use of structural MRI in Alzheimer disease

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The cultural context of visual hallucinations

scientific article published on February 2008

The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

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The diagnosis of young-onset dementia.

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The effect of APOE genotype on clinical phenotype in Alzheimer disease

scientific article published on 01 August 2006

The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial

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The heritability and genetics of frontotemporal lobar degeneration.

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The importance of group-wise registration in tract based spatial statistics study of neurodegeneration: a simulation study in Alzheimer's disease

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The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy

scientific article published on 24 April 2013

The natural history of Alzheimer disease: a longitudinal presymptomatic and symptomatic study of a familial cohort

scientific article published in November 2004

The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study

scientific article published on 18 September 2013

The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study

scientific article published in December 2009

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

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The search for early markers of AD: hippocampal atrophy and memory deficits

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Tracking atrophy progression in familial Alzheimer's disease: a serial MRI study

scientific article published in October 2006

Tracking progression in frontotemporal lobar degeneration: serial MRI in semantic dementia.

scientific article published on October 2008

Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease

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Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

scientific article published in Nature Communications

Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative

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Using nine degrees-of-freedom registration to correct for changes in voxel size in serial MRI studies

scientific article published in September 2004

Using serial registered brain magnetic resonance imaging to measure disease progression in Alzheimer disease: power calculations and estimates of sample size to detect treatment effects

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Using visual rating to diagnose dementia: a critical evaluation of MRI atrophy scales

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VBM signatures of abnormal eating behaviours in frontotemporal lobar degeneration

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Validation of next-generation sequencing technologies in genetic diagnosis of dementia

scientific article published on 31 August 2013

Vascular Dementia

scholarly article published 20 October 2010

Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls

scientific article published on 21 March 2013

Visual assessment of atrophy on magnetic resonance imaging in the diagnosis of pathologically confirmed young-onset dementias.

scientific article

Visual assessment of posterior atrophy development of a MRI rating scale

scientific article published on 31 July 2011

Visual ratings of atrophy in MCI: prediction of conversion and relationship with CSF biomarkers

scientific article published on 18 April 2012

Visual short-term memory binding deficit in familial Alzheimer's disease.

scientific article published on 6 February 2016

Visualisation and quantification of rates of atrophy in Alzheimer's disease.

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Visualizing the emergence of posterior cortical atrophy

scientific article published on 25 October 2011

Visuomotor integration deficits are common to familial and sporadic preclinical Alzheimer’s disease

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Volume changes in Alzheimer's disease and mild cognitive impairment: cognitive associations

scientific article published on 16 September 2009

Volumetric MRI and cognitive measures in Alzheimer disease : comparison of markers of progression

scientific article published on 18 February 2008

Voxel-based morphometry detects patterns of atrophy that help differentiate progressive supranuclear palsy and Parkinson's disease

article

Vulnerability to neuroleptic side effects in frontotemporal lobar degeneration.

scientific article published in January 2003

When, where, and how does Alzheimer's disease start?

scientific article published on November 6, 2012

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

article by Miguel Ángel Araque Caballero et al published 1 October 2018 in Brain

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease.

scientific article published on 9 May 2018

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

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White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy

scientific article published on 09 December 2016

White matter tract signatures of impaired social cognition in frontotemporal lobar degeneration

scientific article

White matter tract signatures of the progressive aphasias

scientific article published on 9 January 2013

Whole-brain atrophy as a measure of progression in premanifest and early Huntington's disease

scientific article published in April 2009

Whole-brain atrophy rate and cognitive decline: longitudinal MR study of memory clinic patients

scientific article published on 23 June 2008

Whole-brain atrophy rate in Alzheimer disease: identifying fast progressors.

scientific article published in May 2008

Why has therapy development for dementia failed in the last two decades?

scientific article published on 19 December 2015

Word-finding difficulty: a clinical analysis of the progressive aphasias

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