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List of works by Miguel Medina

A delta-catenin signaling pathway leading to dendritic protrusions

scientific article published on 22 September 2008

A longitudinal FDG-PET study of transgenic mice overexpressing GSK- 3β in the brain

scientific article published in February 2014

Additional mechanisms conferring genetic susceptibility to Alzheimer's disease

scientific article

An Overview of the Role of Lipofuscin in Age-Related Neurodegeneration

scientific article published on 05 July 2018

An Overview on the Clinical Development of Tau-Based Therapeutics

scientific article published on 11 April 2018

Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice

scientific article published on 25 June 2008

Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus

scientific article published on 20 September 2018

Bioactive prenylated phenyl derivatives derived from marine natural products: novel scaffolds for the design of BACE inhibitors

article published in 2014

Clinical Relevance of Specific Cognitive Complaints in Determining Mild Cognitive Impairment from Cognitively Normal States in a Study of Healthy Elderly Controls

scientific article published on 04 October 2016

Deconstructing GSK‐3: The Fine Regulation of Its Activity ⬇️

scientific article published on April 28, 2011

Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease

scientific article published on November 2005

Detecting Circulating MicroRNAs as Biomarkers in Alzheimer's Disease

scientific article published on 01 January 2018

Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.

scientific article published on 17 October 2005

Drosophila cathepsin B-like proteinase: a suggested role in yolk degradation

scientific article published in June 1988

Dual binding site acetylcholinesterase inhibitors: potential new disease-modifying agents for AD.

scientific article

Effects of commonly prescribed drugs on cognition and mild cognitive impairment in healthy elderly people

scientific article published on 26 June 2019

Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment

scientific article published on 13 November 2019

EuroTau: towing scientists to tau without tautology.

scientific article

Evidence for a new binding mode to GSK-3: allosteric regulation by the marine compound palinurin.

scientific article

Evidence for irreversible inhibition of glycogen synthase kinase-3β by tideglusib

scientific article

Expression of presenilin 1 in nervous system during rat development

scientific article published in August 1999

Further understanding of tau phosphorylation: implications for therapy.

scientific article published on 02 January 2015

Glycogen synthase kinase 3 phosphorylates recombinant human tau protein at serine-262 in the presence of heparin (or tubulin)

scientific article published on 01 September 1995

Glycogen synthase kinase-3 (GSK-3) inhibitors for the treatment of Alzheimer's disease.

scientific article published on January 2010

Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease.

scientific article

Hemizygosity of delta-catenin (CTNND2) is associated with severe mental retardation in cri-du-chat syndrome

scientific article (publication date: 15 January 2000)

Identification of protein kinases that modify specific epitopes

scientific article published on 01 November 1994

Is tau a prion-like protein?

scientific article published in January 2014

Long runs of homozygosity are associated with Alzheimer's disease

scientific article published on 24 February 2021

Longitudinal Assessment of a Transgenic Animal Model of Tauopathy by FDG-PET Imaging

scientific article published on 01 January 2014

Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases ⬇️

scientific article

MicroRNAs in Neurodegenerative Diseases.

scientific article published on 16 June 2017

Modifications of the 5' untranslated region of foot-and-mouth disease virus after prolonged persistence in cell culture

scientific article published on November 1992

Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies ⬇️

scientific article published on 05 October 2011

NP7 protects from cell death induced by oxidative stress in neuronal and glial midbrain cultures from parkin null mice

scientific article

Neuronal membrane cholesterol loss enhances amyloid peptide generation

scientific article published on December 2004

New Features about Tau Function and Dysfunction

scientific article

New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates--Nrf2 activators and GSK-3 inhibitors.

scientific article published on 24 January 2012

New insights into the role of glycogen synthase kinase-3 in Alzheimer's disease.

scientific article published on 08 October 2013

New perspectives on the role of tau in Alzheimer's disease. Implications for therapy.

scientific article published on 22 January 2014

Overcoming cell death and tau phosphorylation mediated by PI3K-inhibition: a cell assay to measure neuroprotection.

scientific article published on March 2011

Potent beta-amyloid modulators.

scientific article published on 06 March 2008

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

scientific article published on April 1997

Presenilin affects arm/beta-catenin localization and function in Drosophila

scientific article published in November 2000

Protein kinases involved in the phosphorylation of human tau protein in transfected COS-1 cells.

scientific article published on May 1996

Recent Developments in Tau-Based Therapeutics for Neurodegenerative Diseases ⬇️

scientific article published on January 1, 2011

Recent developments in tau-based therapeutics for Alzheimer's disease and related dementsia

scientific article published on 12 June 2015

RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability

scientific article

Role of tau N-terminal motif in the secretion of human tau by End Binding proteins

scientific article published in PLoS ONE

Secretion of full-length Tau or Tau fragments in cell culture models. Propagation of Tau in vivo and in vitro

scientific article published on 05 March 2018

Specific Features of Subjective Cognitive Decline Predict Faster Conversion to Mild Cognitive Impairment.

scientific article published on 8 March 2016

Strong buffering capacity of insect cells. Implications for the baculovirus expression system

scientific article

Tau Assembly into Filaments

scientific article published on 01 January 2018

Tauopathy Analysis in P301S Mouse Model of Alzheimer Disease Immunized With DNA and MVA Poxvirus-Based Vaccines Expressing Human Full-Length 4R2N or 3RC Tau Proteins

scientific article published on 13 March 2020

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

scientific article published on 01 March 2019

The in vitro formation of recombinant tau polymers: effect of phosphorylation and glycation.

scientific article published in April 1996

The need for better AD animal models

scientific article

The role of extracellular Tau in the spreading of neurofibrillary pathology.

scientific article published on 23 April 2014

The role of tau phosphorylation in transfected COS-1 cells

scientific article

The two species of the foot-and-mouth disease virus leader protein, expressed individually, exhibit the same activities

scientific article published in May 1993

Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation

scientific article

Toward common mechanisms for risk factors in Alzheimer's syndrome

scientific article published on 19 September 2017

Treatment of Alzheimer's disease with the GSK-3 inhibitor tideglusib: a pilot study.

scientific article

Understanding the relationship between GSK-3 and Alzheimer's disease: a focus on how GSK-3 can modulate synaptic plasticity processes

scientific article published on May 2013

Use of okadaic acid to identify relevant phosphoepitopes in pathology: a focus on neurodegeneration

scientific article published on 21 May 2013

Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP.

scientific article

delta-catenin is a nervous system-specific adherens junction protein which undergoes dynamic relocalization during development

scientific article published in May 2000

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