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List of works by Jukka Hartikka

A TaqMan reverse transcription polymerase chain reaction (RT-PCR) in vitro potency assay for plasmid-based vaccine products.

scientific article

A cytomegalovirus DNA vaccine induces antibodies that block viral entry into fibroblasts and epithelial cells.

scientific article

Adjuvants for plasmid DNA vaccines

scientific article

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

scientific article published on 01 February 1984

Comparison of nerve growth factor's effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro

scientific article

Comparison of rabbit and mouse models for persistence analysis of plasmid-based vaccines

scientific article published on 26 May 2006

Cyclic AMP promotes the survival of dopaminergic neurons in vitro and protects them from the toxic effects of MPP+

scientific article published in 1995

Cyclic AMP, but not basic FGF, increases the in vitro survival of mesencephalic dopaminergic neurons and protects them from MPP(+)-induced degeneration

scientific article published in June 1992

Development and characterization of lyophilized DNA vaccine formulations

scientific article published in January 2000

Development of septal cholinergic neurons in culture: plating density and glial cells modulate effects of NGF on survival, fiber growth, and expression of transmitter-specific enzymes

scientific article

Effect of thyroid hormone analogs on the activity of choline acetyltransferase in cultures of dissociated septal cells

scientific article published in June 1986

Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188.

scientific article published in November 2001

Enhancer and promoter chimeras in plasmids designed for intramuscular injection: a comparative in vivo and in vitro study

scientific article published on November 1998

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases

scientific article published on September 1989

Gangliosides alter morphology and growth of astrocytes and increase the activity of choline acetyltransferase in cultures of dissociated septal cells

scientific article published in August 1985

Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice

scientific article published on August 1993

I. Poloxamer-formulated plasmid DNA-based human cytomegalovirus vaccine: evaluation of plasmid DNA biodistribution/persistence and integration.

scientific article

II. Cationic lipid-formulated plasmid DNA-based Bacillus anthracis vaccine: evaluation of plasmid DNA persistence and integration potential.

scientific article published in October 2005

Inhibitors of Type IV Phosphodiesterases Reduce the Toxicity of MPTP in Substantia Nigra NeuronsIn Vivo

scientific article published in December 1995

Localization of nerve growth factor receptors in cholinergic neurons of the human basal forebrain

scientific article

Long-term regulation of serotonergic activity in the rat brain via activation of protein kinase A.

scientific article published on March 1993

Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons

scientific article published in January 1985

Novel, high expressing and antibiotic-controlled plasmid vectors designed for use in gene therapy

scientific article published in April 1996

Pharmacological activities in thermal proteins: relationships in molecular evolution

scientific article published on 01 January 1987

Physical characterization and in vivo evaluation of poloxamer-based DNA vaccine formulations

scientific article published in July 2008

Preclinical evaluation of Vaxfectin-adjuvanted Vero cell-derived seasonal split and pandemic whole virus influenza vaccines

scientific article

Preclinical evaluation of the immunogenicity and safety of plasmid DNA-based prophylactic vaccines for human cytomegalovirus.

scientific article published on 24 August 2012

Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.

scientific article published on December 1992

Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine

scientific article

Sodium phosphate enhances plasmid DNA expression in vivo

scientific article published on July 2000

Spatial-temporal patterns of gene expression in mouse skeletal muscle after injection of lacZ plasmid DNA.

scientific article

Vaxfectin enhances antigen specific antibody titers and maintains Th1 type immune responses to plasmid DNA immunization

scientific article published on 01 June 2001

Vaxfectin enhances the humoral immune response to plasmid DNA-encoded antigens

scientific article published on 01 February 2001

Vaxfectin, a cationic lipid-based adjuvant for protein-based influenza vaccines

scientific article

Vaxfectin: a versatile adjuvant for plasmid DNA- and protein-based vaccines

scientific article published on December 2010

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