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List of works by Mauro Sola-Penna

A Novel Naphthotriazolyl-4-oxoquinoline Derivative that Selectively Controls Breast Cancer Cells Survival Through the Induction of Apoptosis

scientific article published on 01 January 2018

A Novel Triazole Derivative Drug Presenting In Vitro and In Vivo Anticancer Properties

scientific article published on 01 January 2018

A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence.

scientific article

A radioassay for phosphofructokinase-1 activity in cell extracts and purified enzyme

scientific article published in January 2002

Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity

scientific article published on 21 September 2008

Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis

scientific article published on 12 November 2020

Amylin induces hypoglycemia in mice

scientific article published in March 2013

Antidiabetic activity of Sedum dendroideum: metabolic enzymes as putative targets for the bioactive flavonoid kaempferitrin

scientific article published on 10 May 2014

Betaine protects urea-induced denaturation of myosin subfragment-1.

scientific article published on 20 May 2008

Biosynthesis of O-N-acetylglucosamine-linked glycans in Trypanosoma cruzi. Characterization of the novel uridine diphospho-N-acetylglucosamine:polypeptide N-acetylglucosaminyltransferase-catalyzing formation of N-acetylglucosamine alpha1-->O-threoni

scientific article published in June 1998

Calcium influx: a possible role for insulin modulation of intracellular distribution and activity of 6-phosphofructo-1-kinase in human erythrocytes.

scientific article published on 24 August 2005

Calmodulin upregulates skeletal muscle 6-phosphofructo-1-kinase reversing the inhibitory effects of allosteric modulators

scientific article published on 27 February 2009

Carbohydrate protection of enzyme structure and function against guanidinium chloride treatment depends on the nature of carbohydrate and enzyme

scientific article published on 01 August 1997

Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer.

scientific article published in August 2003

Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes

scientific article published in April 2005

Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues.

scientific article

Clotrimazole inhibits and modulates heterologous association of the key glycolytic enzyme 6-phosphofructo-1-kinase

scientific article published on 14 January 2007

Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis

scientific article published on 22 April 2018

Clotrimazole potentiates the inhibitory effects of ATP on the key glycolytic enzyme 6-phosphofructo-1-kinase

scientific article published on 25 March 2010

Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis

scientific article

Counteracting effects of urea and methylamines in function and structure of skeletal muscle myosin.

scientific article published in December 2002

Design, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked-1H-Dibenzo[b,h]xanthenes as Inductors of ROS-Mediated Apoptosis in the Breast Cancer Cell Line MCF-7

scientific article published on 01 January 2019

Discrete Fourier Transform-Based Multivariate Image Analysis: Application to Modeling of Aromatase Inhibitory Activity

scientific article published on 3 January 2018

Effects of Food Additives on Immune Cells As Contributors to Body Weight Gain and Immune-Mediated Metabolic Dysregulation

scientific article published on 6 November 2017

Epinephrine modulates cellular distribution of muscle phosphofructokinase.

scientific article published in April 2003

Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

scientific article published on 18 April 2016

Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice

scientific article published on 11 February 2016

Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes.

scientific article published on 6 February 2010

Glucuronoxylomannan from Cryptococcus neoformans down-regulates the enzyme 6-phosphofructo-1-kinase of macrophages.

scientific article published on 9 March 2011

Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).

scientific article

Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma.

scientific article published on 7 August 2015

Identification of chicoric acid as a hypoglycemic agent from Ocimum gratissimum leaf extract in a biomonitoring in vivo study

scientific article published on 10 January 2014

Inhibition of yeast glutathione reductase by trehalose: possible implications in yeast survival and recovery from stress.

scientific article published in May 2004

Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms

scientific article published on 24 April 2018

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice.

scientific article

Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

scientific article

Mayaro virus infection alters glucose metabolism in cultured cells through activation of the enzyme 6-phosphofructo 1-kinase

scientific article published in November 2004

Metabolic regulation by lactate.

scientific article published on September 2008

Metformin reverses hexokinase and phosphofructokinase downregulation and intracellular distribution in the heart of diabetic mice

scientific article published on 23 June 2012

Microcapsules of alginate/chitosan containing magnetic nanoparticles for controlled release of insulin.

scientific article published on 14 July 2010

Modulation of 6-phosphofructo-1-kinase oligomeric equilibrium by calmodulin: formation of active dimers

scientific article published on 22 December 2005

Monosaccharides and Disaccharides Decrease the K m for Phosphorylation of a Membrane-Bound Enzyme ATPase ⬇️

scientific article published on July 1, 1991

Muscle-type 6-phosphofructo-1-kinase and aldolase associate conferring catalytic advantages for both enzymes.

scientific article

Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells

scientific article

Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway.

scientific article published on 28 March 2018

Opposing effects of two osmolytes--trehalose and glycerol--on thermal inactivation of rabbit muscle 6-phosphofructo-1-kinase.

scientific article published in January 2005

Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole

scientific article

Phosphofructokinase-P Modulates P44/42 MAPK Levels in HeLa Cells

scientific article published on 28 October 2016

Polymeric particles for the controlled release of human amylin

scientific article published on 28 January 2012

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

scientific article published on 29 June 2017

Protection against thermal denaturation by trehalose on the plasma membrane H+-ATPase from yeast. Synergetic effect between trehalose and phospholipid environment

scientific article published on 01 December 1999

Proteomic analysis of the secretions of Pseudallescheria boydii, a human fungal pathogen with unknown genome

scientific article published on 5 December 2011

Reference genes for quantitative PCR in the adipose tissue of mice with metabolic disease.

scientific article

Regulation of human erythrocyte metabolism by insulin: cellular distribution of 6-phosphofructo-1-kinase and its implication for red blood cell function.

scientific article published on 15 August 2005

Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism

scientific article

Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase.

scientific article

Rhodnius prolixus lipophorin: lipid composition and effect of high temperature on physiological role.

scientific article published on 29 January 2013

SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway

scientific article published on 11 December 2015

Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA, respectively

scientific article published on 10 December 2019

Serotonin modulates hepatic 6-phosphofructo-1-kinase in an insulin synergistic manner.

scientific article

Serotonin regulates 6-phosphofructo-1-kinase activity in a PLC–PKC–CaMK II- and Janus kinase-dependent signaling pathway ⬇️

scientific article published on September 26, 2012

Serotonin regulates an acyl-CoA-binding protein (ACBP) gene expression in the midgut of Rhodnius prolixus.

scientific article published on 15 January 2010

Serotonin stimulates mouse skeletal muscle 6-phosphofructo-1-kinase through tyrosine-phosphorylation of the enzyme altering its intracellular localization

scientific journal article

Stabilization against thermal inactivation promoted by sugars on enzyme structure and function: why is trehalose more effective than other sugars?

scientific article

Subversion of Schwann Cell Glucose Metabolism by Mycobacterium leprae

scientific article published on 23 August 2016

Subversion of Schwann cell glucose metabolism by Mycobacterium leprae

scientific article published on November 2016

The Use of NMR Metabolite Profiling and in vivo Hypoglycemic Assay for Comparison of Unfractionated Aqueous Leaf Extracts of Two Ocimum Species

scientific article

Therapeutic nanosystems for oral administration of insulin.

scientific article published on January 2014

Trehalose and glycerol stabilize and renature yeast inorganic pyrophosphatase inactivated by very high temperatures.

scientific article

Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster

scientific article

Urea increases tolerance of yeast inorganic pyrophosphatase activity to ethanol: the other side of urea interaction with proteins.

scientific article published in October 2001

p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+).

scientific article

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