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List of works by Timothy R. Walsh

1.12 Å resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2.

scientific article

A 1 year surveillance study of glycopeptide-intermediate Staphylococcus aureus strains in a French hospital

scientific article

A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease

scientific article published on February 2016

A clinical isolate of Aeromonas sobria with three chromosomally mediated inducible beta-lactamases: a cephalosporinase, a penicillinase and a third enzyme, displaying carbapenemase activity.

scientific article published in February 1995

A colistin crisis in India.

scientific article published on 30 January 2018

A framework for global surveillance of antibiotic resistance

scientific article published on 08 April 2011

A multi-center blinded study on the efficiency of phenotypic screening methods to detect glycopeptide intermediately susceptible Staphylococcus aureus (GISA) and heterogeneous GISA (h-GISA).

scientific article

A multicenter study evaluating the current strategies for isolating Staphylococcus aureus strains with reduced susceptibility to glycopeptides

scientific article published on 15 November 2006

A new approach to the inhibition of metallo-beta-lactamases.

scientific article

A novel metallo-beta-lactamase, Mbl1b, produced by the environmental bacterium Caulobacter crescentus

scientific article published in December 2001

A one-health approach to antimicrobial resistance

scientific article published on 01 August 2018

A promising target for treatment of multidrug-resistant bacterial infections.

scientific article published on 2 May 2011

Activity of AZD2563, a novel oxazolidinone, against Staphylococcus aureus strains with reduced susceptibility to vancomycin or linezolid

scientific article

Activity of mecillinam against Escherichia coli resistant to third-generation cephalosporins

scientific article published in January 2010

An Emerging Clone, KPC-2-Producing Klebsiella pneumoniae ST16, Associated with High Mortality Rates in a CC258 Endemic Setting

scientific article published on 12 November 2019

Analysis of AmpC beta-lactamase expression and sequence in biochemically atypical ceftazidime-resistant Enterobacteriaceae from paediatric patients

scientific article published on 10 March 2004

Analysis of Salmonella spp. with resistance to extended-spectrum cephalosporins and fluoroquinolones isolated in North America and Latin America: report from the SENTRY Antimicrobial Surveillance Program (1997-2004).

scientific article

Anthropogenic and environmental factors associated with high incidence of mcr-1 carriage in humans across China

article

Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis

scientific article published on 01 September 2018

Antibiotic resistance in acne - Authors' reply.

scientific article

Antibiotic resistance, stewardship, and consumption - Authors' reply

scientific article published on 01 February 2019

Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance

scientific article

Association of blaDHA-1 and qnrB genes carried by broad-host-range plasmids among isolates of Enterobacteriaceae at a Spanish hospital

article

Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms

scientific article published on 12 December 2017

Balkan NDM-1: escape or transplant?

scientific article published in March 2011

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

scientific article published on 16 September 2019

Biochemical characterization of the acquired metallo-beta-lactamase SPM-1 from Pseudomonas aeruginosa.

scientific article

Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases

scientific article published on May 2005

Carbapenem resistance in Klebsiella pneumoniae due to the New Delhi Metallo-β-lactamase

scientific article

Carriage of qnrA1 and qnrB2, blaCTX-M15, and complex class 1 integron in a clinical multiresistant Citrobacter freundii isolate.

scientific article published on 24 March 2010

Cefuroxime resistance in non-beta-lactamase Haemophilus influenzae is linked to mutations in ftsI.

scientific article

Characterization of IncA/C conjugative plasmid harboring bla TEM-52 and bla CTX-M-15 extended-spectrum β-lactamases in clinical isolates of Escherichia coli in Tunisia

scientific article

Characterization of a carbapenemase-producing clinical isolate of Bacteroides fragilis in Scandinavia: genetic analysis of a unique insertion sequence

scientific article published in January 2005

Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India

scientific article

Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital

scientific article published on 30 April 2007

Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low- and middle-income countries

scientific article published on 29 March 2021

Characterization of fluoroquinolone-resistant beta-hemolytic Streptococcus spp. isolated in North America and Europe including the first report of fluoroquinolone-resistant Streptococcus dysgalactiae subspecies equisimilis: report from the SENTRY An

scientific article published on 10 March 2006

Characterization of monomeric L1 metallo-beta -lactamase and the role of the N-terminal extension in negative cooperativity and antibiotic hydrolysis

scientific article

Characterization of plasmids in extensively drug-resistant acinetobacter strains isolated in India and Pakistan

scientific article

China bans colistin as a feed additive for animals

scientific article published on 19 September 2016

Clinical bacteriology in low-resource settings: today's solutions

scientific article

Clinical validation of the SensiTest™ Colistin, a broth microdilution based method to evaluate colistin MICs.

scientific article

Clinically significant carbapenemases: an update.

scientific article

Combating Global Antibiotic Resistance: Emerging One Health Concerns in Lower- and Middle-Income Countries

article

Combination Therapy Strategies Against Multiple-Resistant Streptococcus Suis.

scientific article

Combinatorial events of insertion sequences and ICE in Gram-negative bacteria

scientific article published on 29 July 2011

Combinatorial genetic evolution of multiresistance

scientific article

Comment on: Occurrence, prevalence and genetic environment of CTX-M beta-lactamases in Enterobacteriaceae from Indian hospitals

scientific article published on 8 February 2007

Comment on: Resistance gene naming and numbering: is it a new gene or not?

scientific article published on 3 June 2016

Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons

scientific article published on 02 June 2006

Comparative bactericidal activities of daptomycin and vancomycin against glycopeptide-intermediate Staphylococcus aureus (GISA) and heterogeneous GISA isolates

scientific article

Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones

scientific article published on 02 January 2020

Complete Sequence of p07-406, a 24,179-base-pair plasmid harboring the blaVIM-7 metallo-beta-lactamase gene in a Pseudomonas aeruginosa isolate from the United States

scientific article published on 30 June 2008

Complete Sequence of the FII Plasmid p42-2, Carrying blaCTX-M-55, oqxAB, fosA3, and floR from Escherichia coli

scientific article published on 11 April 2016

Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB

scientific article published on 17 August 2020

Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production

scientific article published on 6 February 2017

Copper Ions and Coordination Complexes as Novel Carbapenem Adjuvants.

scientific article published on 13 November 2017

Crystal Structure of Pseudomonas aeruginosa SPM-1 Provides Insights into Variable Zinc Affinity of Metallo-β-lactamases

scientific article published on 23 January 2006

Crystal Structure of the Mobile Metallo- -Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157

scientific article

Crystal Structures of Pseudomonas aeruginosa GIM-1: Active-Site Plasticity in Metallo- -Lactamases

scientific article

Crystal structures of VIM-1 complexes explain active site heterogeneity in VIM-class metallo-β-lactamases

scientific article published on 23 November 2018

Detection and dissemination of the colistin resistance gene, mcr-1, from isolates and faecal samples in China

scientific article published on 5 January 2017

Dextrin-colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections.

scientific article

Dissemination and diversity of metallo-beta-lactamases in Latin America: report from the SENTRY Antimicrobial Surveillance Program

scientific article published in January 2005

Dissemination of CTX-M-15 beta-lactamase genes carried on Inc FI and FII plasmids among clinical isolates of Escherichia coli in a university hospital in Istanbul, Turkey

scientific article published on 9 January 2008

Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study.

scientific article

Dissemination of genetically diverse NDM-1, -5, -7 producing-Gram-negative pathogens isolated from pediatric patients in Pakistan

scientific article published on 31 May 2019

Distribution and expression of beta-lactamase genes among Aeromonas spp

article

Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of blaNDM-1 in India, Sweden, and the United Kingdom

scientific article

Does broad-spectrum beta-lactam resistance due to NDM-1 herald the end of the antibiotic era for treatment of infections caused by Gram-negative bacteria?

scientific article published on 28 January 2011

Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA): a multinational prospective cohort study

scientific article published in April 2019

Effects of phenotype and genotype on methods for detection of extended-spectrum-beta-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae in Norway.

scientific article published on November 2006

Emergence and persistence of integron structures harbouring VIM genes in the Children's Memorial Health Institute, Warsaw, Poland, 1998-2006.

scientific article published on 18 December 2008

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

scientific article

Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh

scientific article published on 31 August 2019

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

scientific article (publication date: February 2016)

Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans

scientific article published on 27 May 2019

Emergence of the extended-spectrum beta-lactamase GES-1 in a Pseudomonas aeruginosa strain from Brazil: report from the SENTRY antimicrobial surveillance program

scientific article published in June 2004

Emerging Carriage of NDM-5 and MCR-1 in Escherichia coli From Healthy People in Multiple Regions in China: A Cross Sectional Observational Study

scientific article published on 04 December 2018

Emerging carbapenemases: a global perspective

scientific article published on November 1, 2010

Emerging epidemic of metallo-beta-lactamase-mediated resistances

scientific article published in February 2005

Emerging metallo-beta-lactamase-mediated resistances: a summary report from the worldwide SENTRY antimicrobial surveillance program.

scientific article

Endemic heteroresistant glycopeptide intermediate Staphylcoccus aureus (hGISA) comprising unrelated clonal types and not associated with vancomycin therapy

scientific article

Environmental dissemination of mcr-1 positive Enterobacteriaceae by Chrysomya spp. (common blowfly): An increasing public health risk

scientific article published on 16 November 2018

Enzyme kinetics and biochemical analysis of ImiS, the metallo-beta-lactamase from Aeromonas sobria 163a.

scientific article published in March 1996

Erratum for Liu et al., "Plasmid-Mediated Novel blaNDM-17 Gene Encoding a Carbapenemase with Enhanced Activity in a Sequence Type 48 Escherichia coli Strain".

scientific article published on 25 January 2018

Erratum for Yin et al., "Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli".

scientific article published on 15 August 2017

Escherichia coli CreBC is a global regulator of gene expression that responds to growth in minimal media

scientific article

Evaluation of a new Etest for detecting metallo-beta-lactamases in routine clinical testing

scientific article published on August 2002

Evaluation of a new Etest vancomycin-teicoplanin strip for detection of glycopeptide-intermediate Staphylococcus aureus (GISA), in particular, heterogeneous GISA.

scientific article published on 2 July 2008

Evaluation of current methods for detection of staphylococci with reduced susceptibility to glycopeptides

scientific article published on July 2001

Evaluation of the effectiveness of common hospital hand disinfectants against methicillin-resistant Staphylococcus aureus, glycopeptide-intermediate S. aureus, and heterogeneous glycopeptide-intermediate S. aureus

scientific article published in March 2009

Evidence for reduction in breakpoints used to determine vancomycin susceptibility in Staphylococcus aureus

scientific article published on September 2005

Evolution and dissemination of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae: epidemiology and molecular report from the SENTRY Antimicrobial Surveillance Program (1997-2003).

scientific article published in January 2005

Evolution of the ISCR3 group of ISCR elements

scientific article published on 28 July 2008

Expression and detection of hetero-vancomycin resistance in Staphylococcus aureus

scientific article published in November 1999

Expression of tcaA and mprF and glycopeptide resistance in clinical glycopeptide-intermediate Staphylococcus aureus (GISA) and heteroGISA strains

scientific article

Extended spectrum ß-lactamase-producing Escherichia coli among backyard poultry farms, farmers, and environments in Thailand

scientific article published on 01 June 2019

Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria.

scientific article published on 06 June 2012

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

scientific article published on 01 March 2020

First description of Klebsiella pneumoniae clinical isolates carrying both qnrA and qnrB genes in Portugal

scientific article published on 3 March 2010

First identification of clinical isolate of a Novel "NDM-4" producing Escherichia coli ST405 from urine sample in Pakistan.

scientific article

First isolation of bla(VIM-2) in Latin America: report from the SENTRY Antimicrobial Surveillance Program

scientific article published in April 2004

First report of mefA and msrA/msrB multidrug efflux pumps associated with blaTEM-1 β-lactamase in Enterococcus faecalis

scientific article published in December 2011

First report of the metallo-beta-lactamase SPM-1 in Europe.

scientific article published on 26 October 2009

Genetic & virulence profiling of ESBL-positive E. coli from nosocomial & veterinary sources

scientific article published on 18 February 2016

Genetic analysis of 17 genes in Staphylococcus aureus with reduced susceptibility to vancomycin (VISA) and heteroVISA.

scientific article

Genetic and biochemical characterization of a novel metallo-β-lactamase, TMB-1, from an Achromobacter xylosoxidans strain isolated in Tripoli, Libya

scientific article

Genetic and biochemical characterization of an acquired subgroup B3 metallo-β-lactamase gene, blaAIM-1, and its unique genetic context in Pseudomonas aeruginosa from Australia

scientific article

Genetic characterization of a novel metallo-beta-lactamase gene, blaIMP-13, harboured by a novel Tn5051-type transposon disseminating carbapenemase genes in Europe: report from the SENTRY worldwide antimicrobial surveillance programme.

scientific article published in September 2003

Genetic environment of colistin resistance genes mcr-1 and mcr-3 in Escherichia coli from one pig farm in China

scientific article published on 12 January 2019

Genetic linkage of the penicillinase gene, amp, and blrAB, encoding the regulator of beta-lactamase expression in Aeromonas spp

article

Global dissemination of a multidrug resistant Escherichia coli clone

scientific article published on 31 March 2014

Global spread of New Delhi metallo-β-lactamase 1

article

Hand hygiene does work

scientific article published on 01 November 2012

Heavy Metal Resistance Genes Are Associated with blaNDM-1- and blaCTX-M-15-Carrying Enterobacteriaceae.

scientific article

Heterogeneous and Flexible Transmission of mcr-1 in Hospital-Associated Escherichia coli.

scientific article

How to detect NDM-1 producers

scientific article published on December 2010

ISCR elements are key players in IncA/C plasmid evolution.

scientific article published on August 2010

ISCR elements: novel gene-capturing systems of the 21st century?

scientific article

ISCR2, another vehicle for bla(VEB) gene acquisition

scientific article published on 24 August 2009

Identification of IncA/C Plasmid Replication and Maintenance Genes and Development of a Plasmid Multilocus Sequence Typing Scheme

scientific article

Identification of carbapenem-resistant Pseudomonas aeruginosa in selected hospitals of the Gulf Cooperation Council States: dominance of high-risk clones in the region.

scientific article published on 17 April 2018

Identification of the novel tigecycline resistance gene tet(X6) and its variants in Myroides, Acinetobacter and Proteus of food animal origin

scientific article published on 18 February 2020

In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii

scientific article published on 01 April 2019

Induction of beta-lactamase production in Aeromonas hydrophila is responsive to beta-lactam-mediated changes in peptidoglycan composition.

scientific article published on 29 April 2010

Infection by and dissemination of NDM-5-producing Escherichia coli in China

scientific article published on 4 November 2015

Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1

scientific article published on 06 January 2017

Integrated aquaculture contributes to the transfer of mcr-1 between animals and humans via the aquaculture supply chain

scientific article published on 12 June 2019

Integron carrying a novel metallo-beta-lactamase gene, blaIMP-16, and a fused form of aminoglycoside-resistant gene aac(6')-30/aac(6')-Ib': report from the SENTRY Antimicrobial Surveillance Program.

scientific article published on December 2004

Inter-host Transmission of Carbapenemase-Producing Escherichia coli among Humans and Backyard Animals

scientific article published on 23 October 2019

Italian metallo-beta-lactamases: a national problem? Report from the SENTRY Antimicrobial Surveillance Programme.

scientific article

KPC-2-producing Klebsiella pneumoniae ST147 in a neonatal unit: Clonal isolates with differences in colistin susceptibility attributed to AcrAB-TolC pump

scientific article published on 16 January 2020

Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family

scientific article

MCR-1-producing Klebsiella pneumoniae outbreak in China.

scientific article published in June 2017

MDRO Beijing Consensus Meeting Report: Global burden of multidrug-resistant organisms' current antimicrobial resistance problems in Asia-Pacific

scientific article published on 8 November 2013

Mechanisms Involved in Acquisition of blaNDM Genes by IncA/C2 and IncFIIY Plasmids.

scientific article published on 25 April 2016

Metallo-beta-lactamases: the quiet before the storm?

scientific article

Molecular Insights into Functional Differences between mcr-3- and mcr-1-Mediated Colistin Resistance

scientific article published on 27 August 2018

Molecular analysis of the sequences surrounding blaOXA-45 reveals acquisition of this gene by Pseudomonas aeruginosa via a novel ISCR element, ISCR5

scientific article published on 8 December 2008

Molecular and biochemical characterization of OXA-45, an extended-spectrum class 2d' beta-lactamase in Pseudomonas aeruginosa.

scientific article published on September 2003

Molecular characterization of VIM-producing Klebsiella pneumoniae from Scandinavia reveals genetic relatedness with international clonal complexes encoding transferable multidrug resistance

scientific article published on 20 May 2011

Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase.

scientific article published on December 2004

Molecular characterization of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in the countries of the Gulf cooperation council: dominance of OXA-48 and NDM producers

scientific article

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii isolates in the Gulf Cooperation Council States: dominance of OXA-23-type producers

scientific article

Molecular epidemiology of metallo-beta-lactamase-producing Pseudomonas aeruginosa isolates from Norway and Sweden shows import of international clones and local clonal expansion

scientific article

Multicenter Clinical and Molecular Epidemiological Analysis of Bacteremia Due to Carbapenem-Resistant Enterobacteriaceae (CRE) in the CRE Epicenter of the United States

scientific article published on 6 February 2017

Multiplex PCR for detection of acquired carbapenemase genes

scientific article

NDM-1 polymicrobial infections including Vibrio cholerae

scientific article published in The Lancet

New Delhi metallo-β-lactamase 1 – Authors' reply

article

New Delhi metallo-β-lactamase-1: detection and prevention.

scientific article

Nosocomial outbreak of CTX-M-15-producing E. coli in Norway

scientific article published on 01 February 2007

Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli

scientific article

Novel Plasmid-Mediated tet(X5) Gene Conferring Resistance to Tigecycline, Eravacycline, and Omadacycline in a Clinical Acinetobacter baumannii Isolate

scientific article published on 20 December 2019

Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase

scientific article published on 6 July 2001

Novel partners with colistin to increase its in vivo therapeutic effectiveness and prevent the occurrence of colistin resistance in NDM- and MCR-co-producing Escherichia coli in a murine infection model

scientific article published on 01 January 2019

Occurrence and current frequency of CTX-M-type β-lactamases from a regional hospital in the South West of England

article

Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study

scientific article published on 17 November 2016

Origin of low mammalian cell toxicity in a class of highly active antimicrobial amphipathic helical peptides

scientific article published on 23 April 2008

Outbreak of Hypervirulent Multi-Drug Resistant Klebsiella variicola causing high mortality in neonates in Bangladesh

scientific article published on 01 March 2019

Over-expression, purification, and characterization of metallo-beta-lactamase ImiS from Aeromonas veronii bv. sobria

scientific article

Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics.

scientific article

Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases

scientific article published in March 2004

Pharmacodynamics of ceftazidime plus the serine beta-lactamase inhibitor AM-112 against Escherichia coli containing TEM-1 and CTX-M-1 beta-lactamases

scientific article published on November 2004

Plasmid carriage of bla NDM-1 in clinical Acinetobacter baumannii isolates from India

scientific article published on 21 April 2014

Plasmid location and molecular heterogeneity of the L1 and L2 beta-lactamase genes of Stenotrophomonas maltophilia.

scientific article published on February 2001

Plasmid typing and genetic context of AmpC β-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes: findings from a Spanish hospital 1999-2007.

scientific article

Plasmid-Mediated Novel blaNDM-17 Gene Encoding a Carbapenemase with Enhanced Activity in a Sequence Type 48 Escherichia coli Strain

scientific article published on 27 February 2017

Presence of VIM-Positive Pseudomonas Species in Chickens and Their Surrounding Environment.

scientific article published on 24 April 2017

Prevalence and Genetic Analysis of mcr-3-Positive Aeromonas Species from Humans, Retail Meat, and Environmental Water Samples

scientific article published on 27 August 2018

Prevalence and clinical burden of NDM-1 positive infections in pediatric and neonatal patients in Pakistan.

scientific article published on April 2015

Prevalence and risk factors for intestinal carriage of CTX-M-type ESBLs in Enterobacteriaceae from a Thai community.

scientific article published on 16 September 2017

Prevalence of SXT/R391-like integrative and conjugative elements carrying blaCMY-2 in Proteus mirabilis

scientific article published in 2011

Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study.

scientific article published on 27 January 2017

Profiling interactions of vaborbactam with metallo-β-lactamases

scientific article published on 17 May 2019

Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes

article

Pseudomonas aeruginosa strains harbouring an unusual blaVIM-4 gene cassette isolated from hospitalized children in Poland (1998-2001).

scientific article published on 28 January 2004

Redefining extended-spectrum beta-lactamases: balancing science and clinical need

scientific article published on 28 October 2008

Reduced expression of the atl autolysin gene and susceptibility to autolysis in clinical heterogeneous glycopeptide-intermediate Staphylococcus aureus (hGISA) and GISA strains

scientific article

Reply to “Genetic Contexts of blaNDM-1”.

scientific article published in November 2012

Resistance to antibiotics and biocides among non-fermenting Gram-negative bacteria

scientific article published in June 2001

Risk Factors for Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Carriage in Patients Admitted to Intensive Care Unit in a Tertiary Care Hospital in Thailand

scientific article published on 29 May 2019

Risk Factors for Gastrointestinal Colonization and Acquisition of Carbapenem-Resistant Gram-Negative Bacteria among Patients in Intensive Care Units in Thailand

scientific article published on 27 July 2018

Role of the 'cre/blr-tag' DNA sequence in regulation of gene expression by the Aeromonas hydrophila beta-lactamase regulator, BlrA.

scientific article published on 16 January 2004

Salmonella bloodstream infections: report from the SENTRY Antimicrobial Surveillance Program (1997-2001).

scientific article published in October 2003

Sequence analysis of the L1 metallo-beta-lactamase from Xanthomonas maltophilia

scientific article published in June 1994

Sequence analysis of two chromosomally mediated inducible beta-lactamases from Aeromonas sobria, strain 163a, one a class D penicillinase, the other an AmpC cephalosporinase.

scientific article

Spread of extensively resistant VIM-2-positive ST235 Pseudomonas aeruginosa in Belarus, Kazakhstan, and Russia: a longitudinal epidemiological and clinical study

scientific article

Strain-specific expression levels of pbp4 exist in isolates of glycopeptide-intermediate Staphylococcus aureus (GISA) and heterogeneous GISA.

scientific article published on August 2005

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

scientific article

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

scientific article published in April 2019

Susceptibility testing of Stenotrophomonas maltophilia to carbapenems

scientific article published in July 1997

Tackling antibiotic resistance

scientific article

The AmpC phenotype in Norwegian clinical isolates of Escherichia coli is associated with an acquired ISEcp1-like ampC element or hyperproduction of the endogenous AmpC.

scientific article published on 26 June 2008

The emergence of pan-resistant Gram-negative pathogens merits a rapid global political response

article

The emerging NDM carbapenemases

scientific article

The first metallo-beta-lactamase identified in norway is associated with a TniC-like transposon in a Pseudomonas aeruginosa isolate of sequence type 233 imported from Ghana

scientific article published on 17 November 2008

The new medical challenge: why NDM-1? Why Indian?

scientific article published on 01 February 2011

The polymyxin derivative NAB739 is synergistic with several antibiotics against polymyxin-resistant strains of Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii

scientific article published on 23 December 2018

The prevalence and mechanisms of vancomycin resistance in Staphylococcus aureus.

scientific article

Thermodynamics of RTA3 peptide binding to membranes and consequences for antimicrobial activity

scientific article

Toxin-antitoxin systems and their role in disseminating and maintaining antimicrobial resistance

scientific article published on 16 March 2017

VIM and IMP metallo-β-lactamases and other extended-spectrum β-lactamases in Escherichia coli and Klebsiella pneumoniae from environmental samples in a Tunisian hospital

scientific article

blaVIM-2-harboring integrons isolated in India, Russia, and the United States arise from an ancestral class 1 integron predating the formation of the 3' conserved sequence

scientific article published on 16 April 2007

blaVIM-7, an evolutionarily distinct metallo-beta-lactamase gene in a Pseudomonas aeruginosa isolate from the United States

scientific article

hGISA: seek and ye shall find

scientific article

mcr-1 in Enterobacteriaceae from Companion Animals, Beijing, China, 2012-2016.

scientific article published on April 2017

pUb6060: a broad-host-range, DNA polymerase-I-independent ColE2-like plasmid

scientific article published in March 2001

β-Lactamase production in key gram-negative pathogen isolates from the Arabian Peninsula

scientific article published on July 2013