List of works by Paul Christou

'Green revolution' genes encode mutant gibberellin response modulators.

scientific article

A golden era—pro-vitamin A enhancement in diverse crops

article

A novel carotenoid, 4-keto-α-carotene, as an unexpected by-product during genetic engineering of carotenogenesis in rice callus.

scientific article

A question of balance: achieving appropriate nutrient levels in biofortified staple crops.

scientific article published on 18 October 2013

A recombinant multimeric immunoglobulin expressed in rice shows assembly-dependent subcellular localization in endosperm cells

article published in 2004

A transgenic rice cell lineage expressing the oat arginine decarboxylase (adc) cDNA constitutively accumulates putrescine in callus and seeds but not in vegetative tissues

article

Abscisic acid and the herbicide safener cyprosulfamide cooperatively enhance abiotic stress tolerance in rice

An alternative strategy for sustainable pest resistance in genetically enhanced crops

scientific article

An in vitro system for the rapid functional characterization of genes involved in carotenoid biosynthesis and accumulation

scientific article published on 8 January 2014

Ascorbic acid synthesis and metabolism in maize are subject to complex and genotype-dependent feedback regulation during endosperm development

scientific article published on 11 July 2013

Bacillus thuringiensis: a century of research, development and commercial applications

scientific article published on 25 February 2011

Biofortification of crops with nutrients: factors affecting utilization and storage

scientific article published on 6 January 2017

Biofortification of plants with altered antioxidant content and composition: genetic engineering strategies

scientific article published on 13 September 2012

Biosafety and risk assessment framework for selectable marker genes in transgenic crop plants: a case of the science not supporting the politics

scientific article published on 14 April 2007

Biotechnology applied to grain legumes

Bottlenecks in carotenoid biosynthesis and accumulation in rice endosperm are influenced by the precursor-product balance

scientific article published on 7 April 2015

Building bridges: an integrated strategy for sustainable food production throughout the value chain

CRISPR/Cas9-induced monoallelic mutations in the cytosolic AGPase large subunit gene APL2 induce the ectopic expression of APL2 and the corresponding small subunit gene APS2b in rice leaves

scientific article published on 11 August 2018

Calling the tunes on transgenic crops: the case for regulatory harmony

Can microbicides turn the tide against HIV?

scientific article published on January 2010

Can plant biotechnology help break the HIV-malaria link?

scientific article published on 06 March 2014

Can the world afford to ignore biotechnology solutions that address food insecurity?

scientific article

Carotenoid-enriched transgenic corn delivers bioavailable carotenoids to poultry and protects them against coccidiosis

scientific article published on 2 April 2015

Cell type specific expression of a CaMV 35S-GUS gene in transgenic soybean plants

article

Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies

scholarly article

Chapter 27 Particle Bombardment

Characteristics of Genome Editing Mutations in Cereal Crops.

scientific article published on 16 September 2016

Cloning and Functional Characterization of the Maize (Zea mays L.) Carotenoid Epsilon Hydroxylase Gene

scientific article published on June 2015

Cloning and functional analysis of the promoters that upregulate carotenogenic gene expression during flower development in Gentiana lutea.

scientific article published on 27 December 2013

Cloning and functional characterization of the maize carotenoid isomerase and β-carotene hydroxylase genes and their regulation during endosperm maturation

scientific article

Combinatorial genetic transformation generates a library of metabolic phenotypes for the carotenoid pathway in maize

scientific article

Combinatorial genetic transformation of cereals and the creation of metabolic libraries for the carotenoid pathway

scientific article

Combined transcript, proteome, and metabolite analysis of transgenic maize seeds engineered for enhanced carotenoid synthesis reveals pleotropic effects in core metabolism

scientific article published on 20 March 2015

Constitutive expression of a barley Fe phytosiderophore transporter increases alkaline soil tolerance and results in iron partitioning between vegetative and storage tissues under stress.

scientific article published on 21 January 2012

Constitutive expression of soybean ferritin cDNA in transgenic wheat and rice results in increased iron levels in vegetative tissues but not in seeds

scientific article published on 01 December 2000

Constitutive versus seed specific expression in transgenic wheat: temporal and spatial control

Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.

scholarly article

Cotransformation frequencies of foreign genes in soybean cell cultures

article

Critical evaluation of strategies for mineral fortification of staple food crops

scientific article published on 15 August 2009

Dedifferentiation-mediated changes in transposition behavior make the Activator transposon an ideal tool for functional genomics in rice

Deletion of the C-terminal 138 amino acids of the wheat FKBP73 abrogates calmodulin binding, dimerization and male fertility in transgenic rice

scientific article published in March 2002

Detection of opines by colorimetric assay.

scientific article published in February 1987

Development of a novel gene transfer system for Cajanus cajan and expression of a monocot arginine decarboxylase cDNA in transformed cell lines

scientific article published in 2001

Development of an efficient transformation system for Catharanthus roseus cell cultures using particle bombardment

article

Direct DNA transfer using electric discharge particle acceleration (ACCELL™ technology)

EU legitimizes GM crop exclusion zones

EU-OSTID: a collection of transposon insertional mutants for functional genomics in rice.

scientific article published in September 2005

Effective control of yellow stem borer and rice leaf folder in transgenic rice indica varieties Basmati 370 and M 7 using the novel δ-endotoxin cry2A Bacillus thuringiensis gene

article by Shahina Bano Maqbool et al published 1998 in Molecular Breeding

Efficient recovery of recombinant proteins from cereal endosperm is affected by interaction with endogenous storage proteins

scientific article published on 17 September 2013

Endogenous enzyme activities and polyamine levels in diverse rice cultivars depend on the genetic background and are not affected by the presence of the hygromycin phosphotransferase selectable marker.

scientific article published on 17 July 2002

Endosperm-specific co-expression of recombinant soybean ferritin and Aspergillus phytase in maize results in significant increases in the levels of bioavailable iron

scientific article

Engineered maize as a source of astaxanthin: processing and application as fish feed.

scientific article published on 12 August 2016

Engineering complex metabolic pathways in plants.

scientific article published on 26 February 2014

Engineering metabolic pathways in plants by multigene transformation.

scientific article published on January 2013

Expression and immunolocalisation of the snowdrop lectin, GNA in transgenic rice plants.

scientific article published in September 1998

Expression of a heterologous S-adenosylmethionine decarboxylase cDNA in plants demonstrates that changes in S-adenosyl-L-methionine decarboxylase activity determine levels of the higher polyamines spermidine and spermine

scientific article published in August 2002

Expression of an engineered cysteine proteinase inhibitor (Oryzacystatin-IΔD86) for nematode resistance in transgenic rice plants

article

Expression of legumin and vicilin genes in pea mutants and the production of legumin in transgenic plants.

scientific article published in October 2001

Expression of multiple insecticidal genes confers broad resistance against a range of different rice pests

article

Expression of snowdrop lectin (GNA) in transgenic rice plants confers resistance to rice brown planthopper

scientific article

Expression of the insecticidal lectin from snowdrop (Galanthus nivalis agglutinin; GNA) in transgenic wheat plants: effects on predation by the grain aphid Sitobion avenae

article

Expression of two consecutive genes of a secondary metabolic pathway in transgenic tobacco: molecular diversity influences levels of expression and product accumulation

article

Fast quantitative method for the analysis of carotenoids in transgenic maize

scientific article published on 24 May 2013

Field trials and tribulations--making sense of the regulations for experimental field trials of transgenic crops in Europe

scientific article published on 30 January 2012

Freedom-to-operate analysis of a transgenic multivitamin corn variety.

scientific article published on 15 October 2015

From medicinal plants to medicines in plants: plant factories for the production of valuable pharmaceuticals

scientific article published in January 2013

Functional characterization of the Gentiana lutea zeaxanthin epoxidase (GlZEP) promoter in transgenic tomato plants

scientific article published in October 2012

Functional characterization of the recombinant HIV-neutralizing monoclonal antibody 2F5 produced in maize seeds

article

Functional expression of tropinone reductase I (trI) and hyoscyamine-6β-hydroxylase (h6h) from Hyoscyamus niger in Nicotiana tabacum

scientific article published in 2002

Going to ridiculous lengths—European coexistence regulations for GM crops

High-value products from transgenic maize

Identification of carotenoids using mass spectrometry

scientific article

Identification of line-specific strategies for improving carotenoid production in synthetic maize through data-driven mathematical modeling.

scientific article

Introns are key regulatory elements of rice tubulin expression

scientific article published on 19 November 2003

Knowledge-driven approaches for engineering complex metabolic pathways in plants

scientific article

Large-scale chromatin decondensation induced in a developmentally activated transgene locus.

scientific article published on 15 February 2005

Linear transgene constructs lacking vector backbone sequences generate low-copy-number transgenic plants with simple integration patterns

scientific article published on 01 February 2000

Linear transgene constructs lacking vector backbone sequences generate transgenic rice plants which accumulate higher levels of proteins conferring insect resistance

article

Maize plants: An ideal production platform for effective and safe molecular pharming

article

Matrix attachment regions increase transgene expression levels and stability in transgenic rice plants and their progeny

article

Metabolic engineering of ketocarotenoid biosynthesis in higher plants

scientific article published on 29 October 2008

Metabolic engineering of plant secondary products: which way forward?

scientific article

Mice fed on a diet enriched with genetically engineered multivitamin corn show no sub-acute toxic effects and no sub-chronic toxicity

scientific article published on 29 August 2012

Modulation of the polyamine biosynthetic pathway in transgenic rice confers tolerance to drought stress

scholarly article

Molecular Characteristics of Transgenic Wheat and the Effect on Transgene Expression

article

Molecular characterization of the Arginine decarboxylase gene family in rice

scientific article published on 16 January 2010

Molecular characterization of transforming plasmid rearrangements in transgenic rice reveals a recombination hotspot in the CaMV 35S promoter and confirms the predominance of microhomology mediated recombination

scientific article published in 1999

Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants

scientific article

Molecular farming in plants: host systems and expression technology

scientific article

Molecular pharming in cereal crops

Multiple traits of agronomic importance in transgenic indica rice plants: analysis of transgene integration patterns, expression levels and stability

Native and artificial reticuloplasmins co-accumulate in distinct domains of the endoplasmic reticulum and in post-endoplasmic reticulum compartments

scientific article

Nutritionally enhanced crops and food security: scientific achievements versus political expediency

scientific article

Nutritionally important carotenoids as consumer products

article published in 2014

Nutritious crops producing multiple carotenoids--a metabolic balancing act.

scientific article published on 06 September 2011

Over-expression of a cDNA for human ornithine decarboxylase in transgenic rice plants alters the polyamine pool in a tissue-specific manner

scientific article published in October 2001

Over-expression of the oat arginine decarboxylase cDNA in transgenic rice ( Oryza sativa L.) affects normal development patterns in vitro and results in putrescine accumulation in transgenic plants

article

Overexpression of the calcium-dependent protein kinase OsCDPK2 in transgenic rice is repressed by light in leaves and disrupts seed development

scientific article published on 01 December 2000

Overexpression of the wheat FK506-binding protein 73 (FKBP73) and the heat-induced wheat FKBP77 in transgenic wheat reveals different functions of the two isoforms

scientific article

Paradoxical EU agricultural policies on genetically engineered crops

scientific article published on 25 April 2013

Parameters Influencing Stable Transformation of Rice Immature Embryos and Recovery of Transgenic Plants using Electric Discharge Particle Acceleration

article

Particle bombardment and the genetic enhancement of crops: myths and realities

Particle-bombardment-mediated co-transformation of elite Chinese rice cultivars with genes conferring resistance to bacterial blight and sap-sucking insect pests

article

Patterns of CRISPR/Cas9 activity in plants, animals and microbes

scientific article

Pea Legumin Overexpressed in Wheat Endosperm Assembles into an Ordered Paracrystalline Matrix

scientific article published on 01 April 2001

Philosophy and practice of variety-independent gene transfer into recalcitrant crops

article

Plant biotechnology

article

Plant biotechnology: the importance of being accurate

scientific article published on 14 September 2009

Plant cells as pharmaceutical factories

scientific article published on January 2013

Plant genetic engineering and agricultural biotechnology 1983-2013.

scientific article

Plant-based production of biopharmaceuticals

scientific article published on April 2004

Plantibodies: applications, advantages and bottlenecks

scientific article

Plurality of opinion, scientific discourse and pseudoscience: an in depth analysis of the Séralini et al. study claiming that Roundup™ Ready corn or the herbicide Roundup™ cause cancer in rats

scientific article

Practical considerations for pharmaceutical antibody production in different crop systems

Production of Transgenic Rice (Oryza Sativa L.) Plants from Agronomically Important Indica and Japonica Varieties via Electric Discharge Particle Acceleration of Exogenous DNA into Immature Zygotic Embryos

article

Progress in plant metabolic engineering

article

Promoter diversity in multigene transformation

scientific article published on 31 March 2010

Promoter strength influences polyamine metabolism and morphogenic capacity in transgenic rice tissues expressing the oat adc cDNA constitutively.

scientific article published in February 2000

Realising the value of plant molecular pharming to benefit the poor in developing countries and emerging economies.

scientific article published on 14 October 2013

Recent developments and future prospects in insect pest control in transgenic crops

scientific article (publication date: June 2006)

Recombinant plant-derived pharmaceutical proteins: current technical and economic bottlenecks.

scientific article

Reconstruction of the astaxanthin biosynthesis pathway in rice endosperm reveals a metabolic bottleneck at the level of endogenous β-carotene hydroxylase activity

scientific article

Recovery of Chimeric Rice Plants from Dry Seed using Electric Discharge Particle Acceleration

article

Red Anthocyanins and Yellow Carotenoids Form the Color of Orange-Flower Gentian (Gentiana lutea L. var. aurantiaca)

scientific article

Reduction in the endogenous arginine decarboxylase transcript levels in rice leads to depletion of the putrescine and spermidine pools with no concomitant changes in the expression of downstream genes in the polyamine biosynthetic pathway

scientific article published on 24 July 2003

Resistance to green leafhopper (Nephotettix virescens) and brown planthopper (Nilaparvata lugens) in transgenic rice expressing snowdrop lectin (Galanthus nivalis agglutinin; GNA).

scientific article published in April 2000

Rice cell culture as an alternative production system for functional diagnostic and therapeutic antibodies

scientific article published on 01 January 1999

Seeds as a production system for molecular pharming applications: status and prospects.

scientific article published on January 2013

Simultaneous expression of Arabidopsis ρ-hydroxyphenylpyruvate dioxygenase and MPBQ methyltransferase in transgenic corn kernels triples the tocopherol content

Sowing the seeds of success: pharmaceutical proteins from plants.

scientific article

Spermine facilitates recovery from drought but does not confer drought tolerance in transgenic rice plants expressing Datura stramonium S-adenosylmethionine decarboxylase

scientific article published on 21 February 2009

Stable transgenes bear fruit

scientific article published on June 2008

Strategic patent analysis in plant biotechnology: terpenoid indole alkaloid metabolic engineering as a case study

scientific article published on February 2014

Strategies for variety-independent genetic transformation of important cereals, legumes and woody species utilizing particle bombardment

article

Synergistic metabolism in hybrid corn indicates bottlenecks in the carotenoid pathway and leads to the accumulation of extraordinary levels of the nutritionally important carotenoid zeaxanthin.

scientific article

Tagged Transcriptome Display (TTD) in indica rice using Ac transposition

scientific article published on 01 September 2001

Targeted transcriptomic and metabolic profiling reveals temporal bottlenecks in the maize carotenoid pathway that may be addressed by multigene engineering

scientific article published on 30 May 2013

The Arabidopsis ORANGE (AtOR) gene promotes carotenoid accumulation in transgenic corn hybrids derived from parental lines with limited carotenoid pools.

scientific article published on 17 March 2017

The Quest to Understand the Basis and Mechanisms that Control Expression of Introduced Transgenes in Crop Plants

scientific article published on July 2006

The Silencing of Carotenoid β-Hydroxylases by RNA Interference in Different Maize Genetic Backgrounds Increases the β-Carotene Content of the Endosperm.

scientific article published on 24 November 2017

The application of GMOs in agriculture and in food production for a better nutrition: two different scientific points of view

scientific article

The carotenoid cleavage dioxygenase CCD2 catalysing the synthesis of crocetin in spring crocuses and saffron is a plastidial enzyme.

scientific article published on 17 September 2015

The contribution of transgenic plants to better health through improved nutrition: opportunities and constraints

scientific article (publication date: 2013)

The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage

scientific article published on 14 October 2016

The genetic manipulation of medicinal and aromatic plants

scientific article published on 3 July 2007

The green fluorescent protein (GFP) as a vital screenable marker in rice transformation

The humanitarian impact of plant biotechnology: recent breakthroughs vs bottlenecks for adoption

scientific article published on 25 January 2010

The intracellular fate of a recombinant protein is tissue dependent

scientific article published on 21 April 2006

The maize streak virus coat protein transcription unit exhibits tissue-specific expression in transgenic rice

scientific article published in June 2000

The potential impact of plant biotechnology on the Millennium Development Goals

scientific article published on 20 January 2011

The potential of genetically enhanced plants to address food insecurity

scientific article

The production of recombinant pharmaceutical proteins in plants.

scientific article

The regulation of carotenoid pigmentation in flowers

scientific article published on 03 August 2010

Trace and traceability—a call for regulatory harmony

Transcriptional regulation of the rice arginine decarboxylase (Adc1) and S-adenosylmethionine decarboxylase (Samdc) genes by methyl jasmonate

scientific article published on 28 January 2010

Transformation of Plants with Multiple Cassettes Generates Simple Transgene Integration Patterns and High Expression Levels

article

Transformation of the tropane alkaloid-producing medicinal plant Hyoscyamus muticus by particle bombardment.

scientific article published in June 2000

Transformation technology

article

Transgene expression in rice engineered through particle bombardment: molecular factors controlling stable expression and transgene silencing

scientific article published in 1999

Transgene integration, organization and interaction in plants

scientific article

Transgenic cell lines as a useful tool to study the biochemistry of down-regulation of an endogenous rice gene using a heterologous diamine-oxidase cDNA

article

Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways

scholarly article

Transgenic plants for insect pest control: a forward looking scientific perspective.

scientific article

Transgenic rice as a system to study the stability of transgene expression: multiple heterologous transgenes show similar behaviour in diverse genetic backgrounds

article published in 2000

Transgenic rice as a vehicle for the production of the industrial enzyme transglutaminase

scientific article published in April 2004

Transgenic rice grains expressing a heterologous ρ-hydroxyphenylpyruvate dioxygenase shift tocopherol synthesis from the γ to the α isoform without increasing absolute tocopherol levels

scientific article published on 24 February 2012

Transgenic rice plants expressing the ferredoxin-like protein (AP1) from sweet pepper show enhanced resistance to Xanthomonas oryzae pv. oryzae

article

Transgenic strategies for the nutritional enhancement of plants

scientific article

Transgenic wheat plants expressing an oat arginine decarboxylase cDNA exhibit increases in polyamine content in vegetative tissue and seeds

article

Transposon Insertional Mutagenesis in Rice

scientific article published on 01 March 2001

Travel advice on the road to carotenoids in plants

article

Unexpected deposition patterns of recombinant proteins in post-endoplasmic reticulum compartments of wheat endosperm

scientific article

When more is better: multigene engineering in plants

scientific article published on 21 October 2009

Widely separated multiple transgene integration sites in wheat chromosomes are brought together at interphase

scientific article published on 01 December 2000

ZmPBF and ZmGAMYB transcription factors independently transactivate the promoter of the maize (Zea mays) β-carotene hydroxylase 2 gene

scientific article published on 04 January 2019

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